Pharmacokinetics in the elderly;Pharmacocinétique chez le sujet âgé

Revue des Maladies Respiratoires

Volumn 19, Issue 3, 2002, Pages 356-362

  Pehourcq F ^a   Molimard, M ^a  

^a HÔPITAL PELLEGRIN   (France)

Author keywords

Elderly; Pharmacokinetics

Indexed keywords

ACEBUTOLOL; ALPHA GLOBULIN; AMIODARONE; ANTIASTHMATIC AGENT; ANTIBIOTIC AGENT; ANTIDEPRESSANT AGENT; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; BETA GLOBULIN; CARBAMAZEPINE; CEPHALOSPORIN DERIVATIVE; CHLORDIAZEPOXIDE; CREATININE; CYTOCHROME P450; DIGOXIN; HIGH DENSITY LIPOPROTEIN; IMIPRAMINE; IMMUNOGLOBULIN; LEVODOPA; LOW DENSITY LIPOPROTEIN; MACROLIDE; MORPHINE; PENICILLIN G; PHENAZONE; PHENOTHIAZINE DERIVATIVE; PROPRANOLOL; QUINOLONE DERIVATIVE; TUBERCULOSTATIC AGENT; UNINDEXED DRUG; VERAPAMIL; VERY LOW DENSITY LIPOPROTEIN;

AGED; DOSE CALCULATION; DRUG ABSORPTION; DRUG CLEARANCE; DRUG DISTRIBUTION; DRUG ELIMINATION; DRUG EXCRETION; DRUG METABOLISM; ELDERLY CARE; HUMAN; KIDNEY CLEARANCE; KIDNEY FUNCTION; NEPHROTOXICITY; REVIEW; ABSORPTION; AGE; TISSUE DISTRIBUTION;

ABSORPTION; AGE FACTORS; AGED; HUMANS; TISSUE DISTRIBUTION;

EID: 0036063899     PISSN: 07618425     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (53)

1. Pharmacokinetic and pharmacodynamic changes in the elderly
2. Systemic activity of orally administered L-dopa in the elderly Parkinson patient
3. Gastric emptying rate and the systemic availability of levodopa in the elderly parkinsonian patient
4. Contribution of individual differences in gastric emptying to variability in plasma propranolol concentrations
5. The effect of ageing on the hepatic clearance of propranolol
6. Pharmacologie du sujet âgé
7. Kinetic study of serum penicillin concentrations after single doses of benzathine and benthamine penicillins in young and old people
8. The pharmacokinetics of cefuroxime in the elderly
9. The use of intramuscular cefoperazone versus intramuscular ceftriaxone in patients with nursing-home acquired pneumonia
10. Clinical pharmacology
11. Pharmacokinetics and pharmacodynamics of thiopentone
12. Amitriptyline disposition in young and elderly normal men
13. Acetaminophen kinetics in the elderly
14. Measurement and analysis of unbound drug concentrations
15. Age-related changes in protein binding of drugs
16. The classification of drugs on the basis of the drug-binding site on human serum albumin
17. Reduced serum albumin concentration in the elderly: A report from the Boston Collaborative Drug Surveillance Program
18. Pharmacokinetic changes in aging
19. Pharmacogeriatics
20. Age and cytochrome P450-linked drug metabolism in humans: An analysis of 226 subjects with equal histopathologic conditions
21. Drug metabolism in the elderly
22. Antipyrine kinetics in the elderly: Prediction of age-related changes in benzodiazepine oxidizing capacity
23. Metabolism of thioridazine in the elderly
24. Imipramine and desipramine disposition in the elderly
25. Drug therapy: Drug disposition in old age
26. Acetaminophen kinetics in the elderly
27. Single and multiple dose pharmacokinetics of acetaminophen (paracetamol) in polymedicated very old patients with rheumatic pain
28. Pharmacokinetics of metoprolol in healthy, elderly, non-smoking individuals after a single dose and two weeks of treatment
29. Protein binding and disposition of lignocaine in the elderly
30. Aging and drug disposition: An update
31. Effects of age and cigarette smoking on propranolol disposition
32. Impaired enzyme induction by rifampicin in the elderly
33. Aging and drug interactions. I. Effect of cimetidine and smoking on the oxidation of theophylline and cortisol in healthy men
34. Cimetidine impairs clearance of antipyrine and desmethyldiazepam in the elderly
35. Factors affecting the response to inhibition of drug metabolism by cimetidinedose response and sensitivity of elderly and induced subjects
36. The effect of age on creatinine clearance in men: A cross-sectional and longitudinal study
37. Pharmacokinetics in the elderly
38. Plasma levels and renal excretion of phenytoin and its metabolites in patients with renal failure
39. Plasma 10-hydroxynortriptyline in elderly depressed patients
40. Pharmacokinetic studies in elderly people. Are they necessary?
41. Clinical Pharmacokinetics of antibacterial drugs in the elderly. Implications for selection and dosage
42. Quinolones in the elderly
43. Quinolones in the aged
44. Clinical pharmacokinetic properties of the macrolide antibiotics. Effects of age and various pathophysiological states (Part II)
45. Roxithromycin. An update of its antimicrobial activity, pharmacokinetic properties and therapeutic use
46. Pharmacokinetics of cefotaxime and desacetylcefotaxime in elderly patients
47. Influence of age on the pharmacokinetics of ceftazidime in acutely ill adult patients
48. Clinical pharmacokinetics of the antituberculosis drugs
49. Pharmacokinetics of isoniazide: Influence of age
50. Pharmacokinetic studies of rifampicine in the elderly
51. Clinical pharmacokinetics of bambuterol
52. Drug treatment of asthma in the elderly