Cross-resistance to five glucocorticoids in childhood acute lymphoblastic and non-lymphoblastic leukemia samples tested by the MTT assay: Preliminary report

Acta Biochimica Polonica

Volumn 49, Issue 1, 2002, Pages 93-98

  Styczyński, Jan ^a,i   Wysocki, Mariusz ^a   Dȩbski, Robert ^a   Balwierz, Walentyna ^b   Rokicka Milewska, Roma ^c   Matysiak, Michal ^c   Balcerska, Anna ^d   Kowalczyk, Jerzy ^e   Wachowiak, Jacek ^f   Sońta Jakimczyk, Danuta ^g   Chybicka, Alicja ^h  

^a NICOLAUS COPERNICUS UNIVERSITY   (Poland)

^b JAGIELLONIAN UNIVERSITY MEDICAL COLLEGE   (Poland)

^c MEDICAL UNIVERSITY OF WARSAW   (Poland)

^d MEDICAL UNIVERSITY OF GDANSK   (Poland)

^e MEDICAL UNIVERSITY OF LUBLIN   (Poland)

^f POZNAN UNIVERSITY OF MEDICAL SCIENCES   (Poland)

^g MEDICAL UNIVERSITY OF SILESIA   (Poland)

^h WROCLAW MEDICAL UNIVERSITY   (Poland)

ⁱ NONE   (Poland)

Author keywords

Acute leukemia; ALL; AML; Cross resistance; Glucocorticoid resistance; MTT assay; Sensitivity

Indexed keywords

GLUCOCORTICOID; TETRAZOLIUM; THIAZOLE DERIVATIVE; THIAZOLYL BLUE;

ACUTE LYMPHOCYTIC LEUKEMIA; ACUTE NONLYMPHOCYTIC LEUKEMIA; ADOLESCENT; ARTICLE; CHILD; DRUG RESISTANCE; FEMALE; HUMAN; INFANT; MALE; PRESCHOOL CHILD;

ADOLESCENT; CHILD; CHILD, PRESCHOOL; DRUG RESISTANCE, NEOPLASM; FEMALE; GLUCOCORTICOIDS; HUMANS; INFANT; LEUKEMIA, LYMPHOCYTIC, ACUTE; LEUKEMIA, NONLYMPHOCYTIC, ACUTE; MALE; TETRAZOLIUM SALTS; THIAZOLES;

EID: 0036047446     PISSN: 0001527X     EISSN: None     Source Type: Journal    
DOI: 10.18388/abp.2002_3825     Document Type: Article

References (17)

1. Kaspers, G.J., Pieters, R., Klumper, E., De Waal, F.C. & Veerman, A.J. (1994) Glucocorticoid resistance in childhood leukemia. Leuk. Lymphoma 13, 187-201.
2. Schrappe, M., Reiter, A., Ludwig, W.D., Harbott, J., Zimmermann, M., Hiddemann, W., Niemeyer, C., Henze, G., Feldges, A., Zintl, F., Kornhuber, B., Ritter, J., Welte, K., Gadner, H. & Riehm, H. (2000) Improved outcome in childhood acute lymphoblastic leukemia despite reduced use of anthracyclines and cranial radiotherapy: Results of trial ALL-BFM 90. German-Austrian-Swiss ALL-BFM Study Group. Blood 95, 3310-3322.
3. Kofler, R. (2000) The molecular basis of glucocorticoid-induced apoptosis of lymphoblastic leukemia cells. Histochem. Cell Biol. 114, 1-7.
4. Longui, C.A., Vottero, A., Adamson, P.C., Cole, D.E., Kino, T., Monte, O. & Chrousos, G.P. (2000) Low glucocorticoid receptor alpha/beta ratio in T-cell lymphoblastic leukemia. Hormone Metab. Res. 32, 401-406.
5. Gruol, D.J., Vo, Q.D. & Zee, M.C. (1999) Profound differences in the transport of steroids by two mouse P-glycoproteins. Biochem. Pharmacol. 58, 1191-1199.
6. Hala, M., Hartmann, B.L., Bock, G., Geley, S. & Kofler, R. (1999) Glucocorticoid-receptor-gene defects and resistance to glucocorticoid-induced apoptosis in human leukemic cell lines. Int. J. Cancer 68, 663-668.
7. 6-methylguanine-DNA methyl-transferase gene by glucocorticoid hormone. Oncogene 18, 525-532.
8. Creagh, E.M., Sheehan, D. & Cotter, T.G. (2000) Heat shock proteins - modulators of apoptosis in tumour cells. Leukemia 14, 1161-1173.
9. Ito, C., Evans, W.E., McNinch, L., Coustan-Smith, E., Mahmoud, H., Pui, C.H. & Campana, D. (1996) Comparative cytotoxicity of dexamethasone and prednisolone in childhood acute lymphoblastic leukemia. J. Clin. Oncol. 14, 2370-2376.
10. Kaspers, G.J., Veerman, A.J., Popp-Snijders, C., Lomecky, M., Van Zantwijk, C.H., Swinkels, L.M., Van Wering, E.R. & Pieters, R. (1996) Comparison of the antileukemic activity in vitro of dexamethasone and prednisolone in childhood acute lymphoblastic leukemia. Med. Pediatr. Oncol. 27, 114-121.
11. Mihal, V., Hajduch, M., Noskova, V., Feketova, G., Jess, K., Gojova, L., Kasparek, I., Stary, J., Blazek, B., Pospisilova, D. & Novak, Z. (1999) Differential antileukemic activity of prednisolone and dexamethasone in freshly isolated leukemic cells. Adv. Exp. Med. Biol. 457, 461-471.
12. Styczyński, J., Pieters, R., Huismans, D.R., Schuurhuis, G.J., Wysocki, M. & Veerman, A.J.P. (2000) In vitro drug resistance profiles in adult versus childhood acute lymphoblastic leukaemia. Br. J. Haematol. 110, 813-818.
13. DeRijk, R. & Sternberg, E.M. (1997) Corticosteroid resistance and disease. Ann. Med. 29, 79-82.
14. Lamberts, S.W.J., Huizinga, A.T.M., De Lange, P., De Jong, F.H. & Koper, J.W. (1996) Clinical aspects of glucocorticoid resistance. Steroids 61, 157-160.
15. Hongo, T., Yamada, S., Yajima, S., Watanabe, C., Fuji, Y., Kawasaki, H., Yazaki, M., Hanada, R. & Horikoshi, Y. (1999) Biological characteristics and prognostic value of in vitro three-drug resistance to prednisolone, L-asparaginase, and vincristine in childhood acute lymphoblastic leukemia. Int. J. Hematol. 70, 268-277.
16. Schwartz, C.L., Thompson, E.B., Gelber, R.D., Young, M.L., Chilton, D., Cohen, H.J. & Sallan, S.E. (2001) Improved response with higher corticosteroid dose in children with acute lymphoblastic leukemia. J. Clin. Oncol. 19, 1040-1046.
17. Zwaan, C.M., Kaspers, G.J.L., Pieters, R., Ramakers-Van Woerden, N.L., Den Boer, M.L., Wunsche, R., Rottier, M.M.A., Hahlen, K., Van Wering, E., Janka-Schaub, G.E., Creutzig, U. & Veerman, A.J.P. (2000) Cellular drug resistance profiles in childhood acute myeloid leukemia: Differences between FAB types and comparison with acute lymphoblastic leukemia. Blood 96, 2879-2886.