The role of neurotrophins in the pathogenesis of asthma and related diseases: Allergy and asthma as prototypic neuro-immune diseases?

Clinical and Experimental Allergy

Volumn 32, Issue 9, 2002, Pages 1266-1268

  Nockher, W A ^a   Renz, H ^a  

^a PHILIPPS UNIVERSITY MARBURG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ALLERGEN; BRAIN DERIVED NEUROTROPHIC FACTOR; INTERLEUKIN 4; NERVE GROWTH FACTOR; NEUROTROPHIN; NEUROTROPHIN 3; NEUROTROPHIN RECEPTOR; PROTEIN TYROSINE KINASE;

ALLERGIC ASTHMA; ALLERGIC DISEASE; ALLERGIC RHINITIS; ANGIONEUROTIC EDEMA; ATOPIC DERMATITIS; CELL DIFFERENTIATION; CELL INFILTRATION; CELL PROLIFERATION; CELL SURVIVAL; DIMERIZATION; DISEASE ASSOCIATION; EDITORIAL; HUMAN; IMMUNOCOMPETENT CELL; IMMUNOREGULATION; MEMORY CELL; NERVE CELL; NERVE CELL PLASTICITY; NEUROIMMUNOLOGY; NONHUMAN; PATHOGENESIS; PATHOPHYSIOLOGY; PHENOTYPE; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RECEPTOR BINDING; RESPIRATORY TRACT INFLAMMATION; RHINOCONJUNCTIVITIS; SMOOTH MUSCLE TONE; TARGET CELL; URTICARIA;

ASTHMA; BRONCHI; HUMANS; HYPERSENSITIVITY, IMMEDIATE; NERVE GROWTH FACTORS; NEUROIMMUNOMODULATION; RECEPTORS, NERVE GROWTH FACTOR;

EID: 0036042053     PISSN: 09547894     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2745.2002.01489.x     Document Type: Editorial

References (30)

1. Neurotrophins: To cleave or not to cleave
2. Physiology of neurotrophins
3. Neurotrophin signal transduction in the nervous system
4. Circulating nerve growth factor levels are increased in humans with allergic diseases and asthma
5. Stress and atopic eczema
6. Neurotrophins are increased in bronchoalveolar lavage fluid after segmental allergen provocation
7. Nerve growth factor expression and release in allergic inflammatory disease of the upper airways
8. Activated human T cells, B cells, and monocyte produce brain-derived neurotrophic factor in vitro and in inflammatory brain lesions: A neuroprotective role of inflammation?
9. The role of neurotrophins in bronchial asthma
10. Role of nerve growth factor in a mouse model of allergic airway inflammation and asthma
11. Cellular sources of enhanced brain-derived neurotrophic factor production in mouse model of allergic inflammation
12. Neurotrophin and neurotrophin receptor expression in alveolar macrophages: An immunocytochemical study
13. Human eosinophils produce neurotrophins and secrete nerve growth factor on immunologic stimuli
14. Mast cells differentially express and release active high molecular weight neurotrophins
15. The role of neurotrophins in allergic bronchial asthma
16. Expression of neurotrophins and their receptors in human bone marrow
17. Activation of the specific neurotrophin receptors TrkA, TrkB and TrKC influences the function of eosinophils
18. Control of nerve growth and plasticity
19. Nerve growth factor-induced phenotypic switch in guinea pig airway sensory neurons
20. Targeted mutation of the gene encoding the low affinity NGF receptor p75 leads to deficits in the peripheral sensory nervous system
21. Hyperinnervation of the airways in transgenic mice overexpressing nerve growth factor
22. Neurokinin A is the predominant tachykinin in human bronchoalveolar lavage fluid in normal and asthmatic subjects
23. Differential regulation of substance P by all members of the nerve growth factor family of neurotrophins in avian dorsal root ganglia throughout development
24. Sensory nerves promote ozone-induced lung inflammation in mice
25. Nerve growth factor or IL-3 induces more IL-13 production from basophils of allergic subjects than from basophils of nonallergic subjects
26. Nerve growth factor is an autocrine survival factor for memory B lymphocytes
27. NGF rescues human B lymphocytes from anti-IgM induced apoptosis by activation of PKCzeta
28. Nerve growth factor prevents apoptosis of cord blood-derived human cultured mast cells synergistically with stem cell factor
29. Ligand activation of nerve growth factor receptor TrkA protects monocytes from apoptosis
30. Abundant production of brain-derived neurotrophic factor by adult visceral epithelia