Superior effect of 9-cis retinoic acid (RA) compared with all-trans RA and 13-cis RA on the inhibition of clonogenic cell growth and the induction of apoptosis in OCI/AML-2 subclones: Is the p53 pathway involved?

British Journal of Haematology

Volumn 118, Issue 2, 2002, Pages 401-410

  Koistinen, Pirjo ^a,b   Zheng, Aiping ^a   Säily, Marjaana ^a   Siitonen, Timo ^a   Mäntymaa, Pentti ^a   Savolainen, Eeva Riitta ^a  

^a OULU UNIVERSITY HOSPITAL   (Finland)

^b UNIVERSITY OF OULU   (Finland)

Author keywords

AML; Apoptosis; bcl 2; p53; Retinoids

Indexed keywords

ALITRETINOIN; ISOTRETINOIN; PROTEIN BCL 2; PROTEIN P53; RETINOIC ACID; RETINOIC ACID RECEPTOR ALPHA;

ACUTE GRANULOCYTIC LEUKEMIA; APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CANCER INHIBITION; CELL CLONE; CELL GROWTH; CELL NUCLEUS; CELL TRANSPORT; CLONOGENESIS; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; CYTOSOL; DRUG EFFECT; DRUG MECHANISM; DRUG POTENCY; GROWTH INHIBITION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN CONFORMATION; PROTEIN TRANSPORT;

ANTINEOPLASTIC AGENTS; APOPTOSIS; BLOTTING, WESTERN; CELL COUNT; CELL DIVISION; DOSE-RESPONSE RELATIONSHIP, DRUG; FLOW CYTOMETRY; FLUORESCENCE; HUMANS; ISOTRETINOIN; LEUKEMIA, MYELOCYTIC, ACUTE; PROTO-ONCOGENE PROTEINS C-BCL-2; RECEPTORS, RETINOIC ACID; TRETINOIN; TUMOR CELLS, CULTURED; TUMOR SUPPRESSOR PROTEIN P53;

EID: 0036039409     PISSN: 00071048     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2141.2002.03743.x     Document Type: Article

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