Restoration of T cell-specific V(D)J recombination in DNA-PKcs-/- mice by ionizing radiation: The effects on survival, development, and tumorigenesis

Acta Biochimica et Biophysica Sinica

Volumn 34, Issue 2, 2002, Pages 149-157

  Li, Xiao Ling ^a   Shen, Shou Rong ^a   Wang, Sa ^b   Ouyang, Hong Hai ^b   Li, Gloria C ^b  

^a Central South University   (China)

^b MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

Author keywords

Apoptosis; DNA DSB repair; DNA PKcs; Tumorigenesis; V(D)J recombination

Indexed keywords

DNA DEPENDENT PROTEIN KINASE; T LYMPHOCYTE RECEPTOR; DNA BINDING PROTEIN; LYMPHOCYTE ANTIGEN RECEPTOR; PROTEIN SERINE THREONINE KINASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CARCINOGENESIS; CELL MATURATION; CELL MUTANT; CELL SURVIVAL; COLONY FORMATION; CONTROLLED STUDY; DNA DAMAGE; DNA REPAIR; EMBRYO; ENZYME DEFICIENCY; FIBROBLAST CULTURE; GAMMA RADIATION; GENETIC RECOMBINATION; IONIZING RADIATION; MOUSE; NEWBORN; NONHUMAN; NULL CELL; RADIATION DOSE; RADIATION EXPOSURE; RADIOSENSITIVITY; T LYMPHOCYTE; ANIMAL; APOPTOSIS; B LYMPHOCYTE; C57BL MOUSE; CELL DIVISION; CELL LINE; CYTOLOGY; FEMALE; GENE REARRANGEMENT; GENETICS; IMMUNOGLOBULIN STRUCTURE; IMMUNOGLOBULIN VARIABLE REGION; LYMPHOMA; MALE; METABOLISM; MOUSE MUTANT; MOUSE STRAIN; MUTATION; RADIATION INJURY; RADIATION RESPONSE; SURVIVAL; THYMOMA;

ANIMALIA;

ANIMALS; ANIMALS, NEWBORN; APOPTOSIS; B-LYMPHOCYTES; CELL DIVISION; CELL LINE; DNA-ACTIVATED PROTEIN KINASE; DNA-BINDING PROTEINS; DOSE-RESPONSE RELATIONSHIP, RADIATION; FEMALE; GAMMA RAYS; GENE REARRANGEMENT, T-LYMPHOCYTE; IMMUNOGLOBULIN JOINING REGION; IMMUNOGLOBULIN VARIABLE REGION; LYMPHOMA; MALE; MICE; MICE, INBRED C57BL; MICE, INBRED STRAINS; MICE, KNOCKOUT; MUTATION; NEOPLASMS, RADIATION-INDUCED; PROTEIN-SERINE-THREONINE KINASES; RECEPTORS, ANTIGEN, T-CELL, ALPHA-BETA; SURVIVAL ANALYSIS; THYMUS NEOPLASMS;

EID: 0036035710     PISSN: 05829879     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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