Fractional hepatic de novo lipogenesis in healthy subjects during near-continuous oral nutrition and bed rest: A comparison with published data in artificially fed, critically ill patients

Clinical Nutrition

Volumn 21, Issue 4, 2002, Pages 345-350

  Minehira, K ^a   Tappy, L ^a   Chiolero, R ^b   Vladimirova, V ^c   Berger, M M ^b   Revelly, J P ^b   Schwarz, J M ^c  

^a University of Lausanne Medical Center   (Switzerland)

^b LAUSANNE UNIVERSITY HOSPITAL   (Switzerland)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Critical illness; Healthy subjects; Lipogenesis; Liver

Indexed keywords

ACETIC ACID; CARBOHYDRATE; CARBON 13; PALMITIC ACID; VERY LOW DENSITY LIPOPROTEIN; CARBON; DIAGNOSTIC AGENT; INSULIN; LIPID;

ADULT; AGED; ARTICLE; ARTIFICIAL FEEDING; BED REST; BRAIN INJURY; CONTROLLED STUDY; CRITICAL ILLNESS; ENTERIC FEEDING; ESOPHAGUS CANCER; FEMALE; HUMAN; HUMAN EXPERIMENT; ISOTOPE LABELING; LIPOGENESIS; LIVER METABOLISM; MALE; MULTIPLE TRAUMA; NORMAL HUMAN; PHYSICAL ACTIVITY; PUBLISHING; RADIOISOTOPE DISTRIBUTION; SUBARACHNOID HEMORRHAGE; SUBDURAL HEMATOMA; THORAX INJURY; BIOSYNTHESIS; CALORIMETRY; CARBOHYDRATE DIET; GLUCOSE BLOOD LEVEL; LIPID METABOLISM; LIVER; METABOLISM; MIDDLE AGED; RADIOIMMUNOASSAY; TIME;

ADULT; BED REST; BLOOD GLUCOSE; CALORIMETRY, INDIRECT; CARBON ISOTOPES; CRITICAL ILLNESS; DIETARY CARBOHYDRATES; ENTERAL NUTRITION; FEMALE; HUMANS; INSULIN; LIPID METABOLISM; LIPIDS; LIVER; MALE; MIDDLE AGED; RADIOIMMUNOASSAY; TIME FACTORS;

EID: 0036022718     PISSN: 02615614     EISSN: None     Source Type: Journal    
DOI: 10.1054/clnu.2002.0559     Document Type: Article

References (20)

1. Regulation of hepatic de novo lipogenesis in humans
2. Human fatty acid synthesis is stimulated by a eucaloric low fat, high carbohydrate diet
3. Mechanisms of action of beta-glucan in postprandial glucose metabolism in healthy men
4. Human fatty acid synthesis is reduced after the substitution of dietary starch for sugar
5. Sterol regulatory element binding protein-1c is a major mediator of insulin action on the hepatic expression of glucokinase and lipogenesis-related genes
6. Glucose and insulin function through two distinct transcription factors to stimulate expression of lipogenic enzyme genes in liver
7. Hepatic and whole-body fat synthesis in humans during carbohydrate overfeeding
8. Effects of isoenergetic glucose-based or lipid-based parenteral nutrition on glucose metabolism, de novo lipogenesis, and respiratory gas exchanges in critically ill patients
9. Effects of enteral carbohydrates on de novo lipogenesis in critically ill patients
10. Measurement of de novo hepatic lipogenesis in humans using stable isotopes
11. Estimation of energy expenditure, net carbohydrate utilization, and net fat oxidation and synthesis by indirect calorimetry; evaluation of errors with special reference to the detailed composition of foods
12. Hepatic de novo lipogenesis after liver transplantation
13. Decreased IRS-2 and increased SREBP-1c lead to mixed insulin resistance and sensitivity in livers of lipodystrophic and ob/ob mice
14. Metabolism and nutritional support
15. Energy metabolism in sepsis and injury
16. Evidence for two classes of cytokines that stimulate hepatic lipogenesis: Relationships among tumor necrosis factor, interleukin-1 and interferon-alpha
17. Hepatic and peripheral glucose metabolism in intensive care patients receiving continuous high- or low-carbohydrate enteral nutrition
18. Isoform 1c of sterol regulatory element binding protein is less active than isoform 1a in livers of transgenic mice and in cultured cells
19. Relationship between carbohydrate-induced hypertriglyceridemia and fatty acid synthesis in lean and obese subjects
20. The biochemistry of energy expenditure