Elimination of virus-specific cytotoxic T cells in the liver

Critical Reviews in Immunology

Volumn 22, Issue 1, 2002, Pages 1-11

  Dennert, Gunther ^a  

^a UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

Author keywords

Fas; Hepatitis; Liver; T cell apoptosis; Tolerance

Indexed keywords

FAS ANTIBODY; FAS LIGAND; INTERLEUKIN 2;

ANTIGEN EXPRESSION; ANTIGEN PRESENTING CELL; CELL DEATH; CELL SPECIFICITY; CELLULAR IMMUNITY; CYTOKINE PRODUCTION; CYTOTOXIC T LYMPHOCYTE; IMMUNE RESPONSE; IMMUNOLOGICAL TOLERANCE; LIVER; NONHUMAN; PRIORITY JOURNAL; REVIEW; T LYMPHOCYTE ACTIVATION; VIRUS INFECTION; ANIMAL; APOPTOSIS; CYTOTOXICITY; HEPATITIS; HUMAN; IMMUNOLOGY; METABOLISM; PATHOLOGY; VIROLOGY;

ANIMAL; APOPTOSIS; CYTOTOXICITY, IMMUNOLOGIC; HEPATITIS; HUMAN; LIVER; SUPPORT, U.S. GOV'T, P.H.S.; T-LYMPHOCYTES, CYTOTOXIC; ANIMALS; HUMANS;

EID: 0036022185     PISSN: 10408401     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (65)

1. Induction of immunological tolerance by porcine liver allografts
2. Reversal of transplantation immunity by liver grafting
3. Murine liver allograft transplantation, tolerance and donor cell chimerism
4. Risks and benefits of weaning immunosuppression in liver transplant recipients, long-term follow-up
5. Combined transplantation of liver and kidney from the same donor protects the kidney from rejection and improves kidney graft survival
6. Transplantation unresponsiveness induced by liver allografts in mouse strains with various histocompatibility disparities
7. To kill or to cure, options in host defense against viral infection
8. Immunopathology of hepatitis C
9. Hepatitis B virus immunopathogenesis
10. b in the liver
11. + T cells results in antigen-specific T-cell tolerance
12. Hepatic suppression of sensitization to antigen absorbed into the portal system
13. Kupffer cell blockade inhibits induction of tolerance by the portal venous route
14. Evidence that an OX-2-positive cell can inhibit the stimulation of type 1 cytokine production by bone marrow-derived B7-1 (and B7-2)-positive dendritic cells
15. Are dendritic cells the key to liver transplant tolerance?
16. Local control of the immune response in the liver
17. Age-related variation in the proportion and activity of murine liver natural killer cells and their cytotoxicity against regenerating hepatocytes
18. + T cells in patients with malignancy
19. Ontogeny and development of extrathymic T cells in mouse liver
20. + T cells are present within a population of intermediate TCR cells
21. + cells, new clues to their origin, specificity, and function
22. Widespread and selective induction of major histocompatibility complex-determined antigens in vivo by gamma interferon
23. NK cell receptors
24. CDI - A new paradigm for antigen presentation and T cell activation
25. NK cells cause liver injury and facilitate the induction of T cell-mediated immunity to a viral liver infection
26. Fas and tumor necrosis factor receptor 1-dependent but not perforin-dependent pathways cause injury in livers infected with an adenovirus construct in mice
27. A distinct IL-18-induced pathway to fully activate NK T lymphocytes independently from TCR engagement
28. Increased interleukin 4 and immunoglobulin E production in transgenic mice overexpressing NK1 T cells
29. + alpha beta T cells activated by IL-12 as a major effector in inhibition of experimental tumor metastasis
30. + T lymphocytes but fail to promote survival
31. Apoptosis within spontaneously accepted mouse liver allografts, evidence for deletion of cytotoxic T cells and implications for tolerance induction
32. Distinct organ-dependent mechanisms for the control of murine cytomegalovirus infection by natural killer cells
33. Requirement for natural killer cell-produced interferon gamma in defense against murine cytomegalovirus infection and enhancement of this defense pathway by interleukin 12 administration
34. + effector function against intracellular infection
35. + T cells induces monocyte chemoattractant protein-1 in early listeriosis
36. + T cells in the Plasmodium yoelii model
37. MHC class I-restricted cytotoxic T lymphocytes to viral antigens destroy hepatocytes in mice infected with E1-deleted recombinant adenoviruses
38. Long-term humoral and cellular immunity induced by a single immunization with replication-defective adenovirus recombinant vector
39. Cytotoxic T-lymphocyte target proteins and their major histocompatibility complex class I restriction in response to adenovirus vectors delivered to mouse liver
40. Cytotoxic T lymphocyte responses to proteins encoded by heterologous transgenes transferred in vivo by adenoviral vectors
41. + T cells within the liver
42. Strange brew, T cells in the liver
43. Antigen presentation by liver cells controls intrahepatic T cell trapping, whereas bone marrow-derived cells preferentially promote intrahepatic T cell apoptosis
44. The T cell chemoattractant IFN-inducible protein 10 is essential in host defense against viral-induced neurologic disease
45. Expression of Mig (monokine induced by interferon-gamma) is important in T lymphocyte recruitment and host defense following viral infection of the central nervous system
46. Upregulation of class I major histocompatibility complex antigens by interferon gamma is necessary for T-cell-mediated elimination of recombinant adenovirus-infected hepatocytes in vivo
47. Expression of class I and class II major histocompatibility complex antigens on human hepatocytes
48. Fas(CD95)/FasL interactions required for programmed cell death after T-cell activation
49. Cell-autonomous Fas (CD95)/Fas-ligand interaction mediates activation-induced apoptosis in T-cell hybridomas
50. Essential roles of the Fas ligand in the development of hepatitis
51. CD95 (Fas) may control the expansion of activated T cells after elimination of bacteria in murine listeriosis
52. Fas (CD95) participates in peripheral T cell deletion and associated apoptosis in vivo
53. Fasmediated apoptosis causes elimination of virus-specific cytotoxic T cells in the virus-infected liver
54. CD40 activation induces apoptosis in cultured human hepatocytes via induction of cell surface Fas ligand expression and amplifies Fasmediated hepatocyte death during allograft rejection
55. Involvement of the CD95 (APO-1/Fas) receptor and ligand in liver damage
56. + T cell development in CD3 zeta-deficient mice
57. Fas and perforin pathways as major mechanisms of T cell-mediated cytotoxicity
58. Cytolytic T-cell cytotoxicity is mediated through perforin and Fas lyric pathways
59. + cells and evidence of usage of T and NK cell receptors
60. Fas-mediated suicide of tumor-reactive T cells following activation by specific tumor, selective rescue by caspase inhibition
61. Herpes simplex virus type 1 infection of activated cytotoxic T cells, induction of fratricide as a mechanism of viral immune evasion
62. Induction of apoptosis in mature T cells by tumour necrosis factor
63. + cells in liver damage and viral control during persistent hepatitis B virus infection
64. Impaired antibody synthesis in patients with chronic hepatitis B infection
65. Lamivudine treatment can restore T cell responsiveness in chronic hepatitis B