CD1 - A new paradigm for antigen presentation and T cell activation

Clinical Immunology and Immunopathology

Volumn 87, Issue 1, 1998, Pages 8-14

  Sugita, Masahiko ^a   Moody, D Branch ^a   Jackman, Robin M ^a   Grant, Ethan P ^a   Rosat, Jean Pierre ^a   Behar, Samuel M ^a   Peters, Peter J ^b   Porcelli, Steven A ^a   Brenner, Michael B ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

^b UTRECHT UNIVERSITY   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

CD1 ANTIGEN; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2;

ANTIGEN EXPRESSION; ANTIGEN PRESENTATION; ARTICLE; HUMAN; IMMUNOREGULATION; INTRACELLULAR TRANSPORT; MAJOR HISTOCOMPATIBILITY COMPLEX; NONHUMAN; PRIORITY JOURNAL; PROTEIN TARGETING; SIGNAL TRANSDUCTION; T LYMPHOCYTE ACTIVATION;

EID: 0031901420     PISSN: 00901229     EISSN: None     Source Type: Journal    
DOI: 10.1006/clin.1997.4500     Document Type: Article

References (41)

1. Germain R. N., Margulies D. H. The biochemistry and cell biology of antigen processing and presentation. Annu. Rev. Immunol. 11:1993;403-450.
2. Heemels M-T., Ploegh H. Generation, translocation, and presentation of MHC class I-restricted peptides. Annu. Rev. Biochem. 64:1995;463-491.
3. Cresswell P. Assembly, transport, and function of MHC class II molecules. Annu. Rev. Immunol. 12:1994;259-293.
4. Fling S. P., Arp B., Pious D. HLA-DMA and -DMB genes are both required for MHC class II/peptide complex formation in antigen presenting cells. Nature. 368:1994;554-558.
5. Burmeister W. P., Huber A. H., Bjorkman P. J. Crystal structure of the complex of rat neonatal Fc receptor with Fc. Nature. 372:1994;379-383.
6. Blumberg, R. S. Gerdes, D. Chott, A. Porcelli, S. A. Balk, S. P. 1995, Structure and function of the CD1 family of MHC-like cell surface proteins, Immunol. Rev. 147, 5, 29, 1995.
7. Burmeister W. P., Gastinel L. N., Simister N. E., Blum M. L., Bjorkman P. J. Crystal structure at 2.2 Å resolution of the MHC-related neonatal Fc receptor. Nature. 372:1994;336-343.
8. Porcelli S. A. The CD1 family: A third lineage of antigen-presenting molecules. Adv. Immunol. 59:1995;1-98.
9. -cytolytic T lymphocytes. Nature. 341:1989;447-450.
10. Faure F., Jitsukawa S., Miossec C., Hercend T. CD1c as a target recognition structure for human T lymphocytes: Analysis with peripheral blood γ/δ cells. Eur. J. Immunol. 20:1990;703-706.
11. Sugita M., Kumagai S., Ota M., Inoko H., Tsuji K., Imura H. Demonstration of the requirement for self antigen in the activation of autoreactive T cells. Int. Immunol. 4:1992;119-124.
12. Calabi F., Milstein C. A novel family of human major histocompatibility complex-related genes not mapping to chromosome 6. Nature. 323:1986;540-543.
13. Albertson D. G., Fishpool R., Sherrington P., Nacheva E., Milstein C. Sensitive and high resolutionin situhybridization to human chromosomes using biotin labelled probes: Assignment of the human thymocyte CD1 antigen genes to chromosome 1. EMBO J. 7:1988;2801-2805.
14. Zeng Z. H., Castaño A. R., Segelke B. W., Stura E. A., Peterson P. A., Wilson I. A. Crystal structure of mouse CD1: An MHC-like fold with a large hydrophobic binding groove. Science. 277:1997;339-345.
15. Bjorkman P. J., Saper M. A., Samraoui B., Bennett W. S., Strominger J. L., Wiley D. C. Structure of the human class I histocompatibility antigen, HLA-A2. Nature. 329:1987;506-512.
16. Bjorkman P. J., Saper M. A., Samraoui B., Bennett W. S., Strominger J. L., Wiley D. C. The foreign antigen binding site and T cell recognition regions of class I histocompatibility antigens. Nature. 329:1987;512-518.
17. Moody D. B., Sugita M., Peters P. J., Brenner M. B., Porcelli S. A. The CD1-restricted T cell response to mycobacteria. Res. Immunol. 147:1996;550-559.
18. -T lymphocytes to a microbial antigen. Nature. 360:1992;593-597.
19. +T cells. Nature. 372:1994;691-694.
20. Sieling P. A., Chatterjee D., Porcelli S. A., Prigozy T. I., Mazzaccaro R. J., Soriano T., Bloom B. R., Brenner M. B., Kronenberg M., Brennan P. J., Modlin R. L. CD1-restricted T cell recognition of microbial lipoglycan antigens. Science. 269:1995;227-230.
21. Beckman E. M., Melián A., Behar S. M., Sieling P. A., Chatterjee D., Furlong S. T., Matsumoto R., Rosat J. P., Modlin R. L., Porcelli S. A. CD1c restricts responses of mycobacteria-specific T cells. Evidence for antigen presentation by a second member of the human CD1 family. J. Immunol. 157:1996;2795-2803.
22. Moody D. B., Reinhold B. B., Guy M. R., Beckman E. M., Frederique D. F., Furlong S. T., Ye S., Reinhold V. N., Sieling P. A., Modlin R. L., Besra G. S., Porcelli S. A. Structural requirements for glycolipid antigen recognition by CD1b-restricted T cells. Science. 278:1997;283-286.
23. Sugita M., Jackman R. M., van Donselaar E., Behar S. M., Rogers R. A., Peters P. J., Brenner M. B., Porcelli S. A. Cytoplasmic tail-dependent localization of CD1b antigen-presenting molecules to MIICs. Science. 273:1996;349-352.
24. Peters P. J., Neefjes J. J., Oorschot V., Ploegh H. L., Geuze H. J. Segregation of MHC class II molecules from MHC class I molecules in the Golgi complex for transport to lysosomal compartments. Nature. 349:1991;669-675.
25. Sanderson F., Kleijmeer M. J., Kelly A., Verwoerd D., Tulp A., Neefjes J. J., Geuze H. J., Trowsdale J. Accumulation of HLA-DM, a regulator of antigen presentation, in MHC class II compartments. Science. 266:1994;1566-1569.
26. Prigozy T. I., Sieling P. A., Clemens D., Stewart P. L., Behar S. M., Porcelli S. A., Brenner M. B., Modlin R. L., Kronenberg M. The mannose receptor delivers lipoglycan antigens to endosomes for presentation to T cells by CD1b molecules. Immunity. 6:1997;187-197.
27. Anderson K. S., Cresswell P. A role for calnexin (IP90) in the assembly of class II MHC molecules. EMBO J. 13:1994;675-682.
28. Sugita M., Brenner M. B. An unstable β2-microglobulin: Major histocompatibility complex class I heavy chain intermediate dissociates from calnexin and then is stabilized by binding peptide. J. Exp. Med. 180:1994;2163-2171.
29. Sugita M., Porcelli S. A., Brenner M. B. Assembly and retention of CD1b heavy chains in the endoplasmic reticulum. J. Immunol. 159:1997;2358-2365.
30. Pearse B. M. F., Robinson M. S. Clathrin, adaptors, and sorting. Annu. Rev. Cell Biol. 6:1990;151-171.
31. Trowbridge I. S., Collawn J. F., Hopkins C. R. Signal-dependent membrane protein trafficking in the endocytic pathway. Annu. Rev. Cell Biol. 9:1993;129-161.
32. Sandoval I. V., Bakke O. Targeting of membrane proteins to endosomes and lysosomes. Trends Cell Biol. 4:1994;292-297.
33. Lindstedt R., Liljedahl M., Péléraux A., Peterson P. A., Karlsson L. The MHC class II molecule H2-M is targeted to an endosomal compartment by a tyrosine-based targeting motif. Immunity. 3:1995;561-572.
34. Sugita M., Brenner M. B. Association of the invariant chain with major histocompatibility complex class I molecules directs trafficking to endocytic compartments. J. Biol. Chem. 270:1995;1443-1448.
35. 2-microglobulin heterodimers, specificity, and influence of the MHC peptide-binding groove. J. Immunol. 157:1996;4503-4510.
36. +T lymphocytes. Science. 268:1995;863-865.
37. -T cells in mice and humans. J. Exp. Med. 180:1994;1097-1106.
38. -T cells. J. Exp. Med. 186:1997;109-120.
39. -cells: B-7 independent costimulation of CD1 restricted cells. J. Exp. Med. 182:1995;2007-2018.
40. June C. H., Bluestone J. A., Nadler L. M., Thompson C. B. The B7 and CD28 receptor families. Immunol. Today. 15:1994;321-330.
41. Stenger S., Mazzaccaro R. J., Uyemura K., Cho S., Barnes P. F., Rosat J.-P., sette A., Brenner M. B., Porcelli S. A., Bloom B. R., Modlin R. L. Differential effects of cytolytic T cell subsets on intracellular infection. Science. 276:1997;1684-1687.