Age-related differences in sensitivity to the antinociceptive effects of kappa opioids in adult male rats

Psychopharmacology

Volumn 162, Issue 3, 2002, Pages 255-264

  Smith, Mark A ^a   French, Adam M ^a  

^a DAVIDSON COLLEGE   (United States)

Author keywords

Age; Analgesia; Antinociception; Kappa; Opioid; Pain; Spiradoline

Indexed keywords

3,4 DICHLORO N METHYL N [2 (1 PYRROLIDINYL)CYCLOHEXYL]BENZENEACETAMIDE; BUTORPHANOL; HOT WATER; KAPPA OPIATE RECEPTOR; N METHYL N [7 (1 PYRROLIDINYL) 1 OXASPIRO[4.5]DEC 8 YL]BENZENEACETAMIDE; NALBUPHINE; OPIATE; SPIRADOLINE; ANALGESIC AGENT; BENZENEACETAMIDE DERIVATIVE; NARCOTIC ANALGESIC AGENT; PYRROLIDINE DERIVATIVE;

AGE; AGED; ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANTINOCICEPTION; ARTICLE; CONTROLLED STUDY; DRUG ANTAGONISM; DRUG EFFECT; DRUG EFFICACY; DRUG POTENTIATION; DRUG SENSITIVITY; HIGH TEMPERATURE; IMMOBILIZATION; LATENT PERIOD; LOW TEMPERATURE; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; TAIL; TEMPERATURE SENSITIVITY; WATER TEMPERATURE; ANALYSIS OF VARIANCE; ANIMAL; COLD; COMPARATIVE STUDY; DOSE RESPONSE; FISCHER 344 RAT; PAIN; PAIN ASSESSMENT; PATHOPHYSIOLOGY; PHYSIOLOGY; REACTION TIME;

3,4-DICHLORO-N-METHYL-N-(2-(1-PYRROLIDINYL)-CYCLOHEXYL)-BENZENEACETAMIDE, (TRANS)-ISOMER; AGE FACTORS; ANALGESICS; ANALGESICS, NON-NARCOTIC; ANALGESICS, OPIOID; ANALYSIS OF VARIANCE; ANIMAL; BUTORPHANOL; COLD; COMPARATIVE STUDY; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG SYNERGISM; MALE; NALBUPHINE; PAIN; PAIN MEASUREMENT; PYRROLIDINES; RATS; RATS, INBRED F344; REACTION TIME; RECEPTORS, OPIOID, KAPPA; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, P.H.S.; ANIMALS; BENZENEACETAMIDES;

EID: 0036020323     PISSN: 00333158     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00213-002-1102-6     Document Type: Article

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