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Volumn 282, Issue 3, 1997, Pages 1253-1261

Butorphanol-mediated antinociception in mice: Partial agonist effects and Mu receptor involvement

Author keywords

[No Author keywords available]

Indexed keywords

3,4 DICHLORO N METHYL N [2 (1 PYRROLIDINYL)CYCLOHEXYL]BENZENEACETAMIDE METHANESULFONATE; BETA FUNALTREXAMINE; BUTORPHANOL TARTRATE; FENTANYL; KAPPA OPIATE RECEPTOR; MORPHINE SULFATE; MU OPIATE RECEPTOR; NALTREXONE; NALTRINDOLE; NORBINALTORPHIMINE;

EID: 0030931722     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (40)

References (56)
  • 1
    • 0009644628 scopus 로고
    • Some quantitative uses of drug antagonists
    • ARUNLAKSHANA, O. AND SCHILD, H. O.: Some quantitative uses of drug antagonists. Br. J. Pharmacol. 14: 48-58, 1959.
    • (1959) Br. J. Pharmacol. , vol.14 , pp. 48-58
    • Arunlakshana, O.1    Schild, H.O.2
  • 4
    • 0028284548 scopus 로고
    • Differential effects of systemically administered nor-binaltorphimine (nor-BNI) on κ-opioid agonists in the mouse writhing assay
    • BROADBEAR, J. H., NEGUS, S. S., BUTELMAN, E. R., DECOSTA, B. R. AND WOODS, J. H.: Differential effects of systemically administered nor-binaltorphimine (nor-BNI) on κ-opioid agonists in the mouse writhing assay. Psychopharmacology 115: 311-319, 1994.
    • (1994) Psychopharmacology , vol.115 , pp. 311-319
    • Broadbear, J.H.1    Negus, S.S.2    Butelman, E.R.3    Decosta, B.R.4    Woods, J.H.5
  • 5
    • 0021857608 scopus 로고
    • Stadol dependence: Another case
    • BROWN, G. R.: Stadol dependence: Another case. JAMA 254: 910, 1985.
    • (1985) JAMA , vol.254 , pp. 910
    • Brown, G.R.1
  • 6
    • 0028795667 scopus 로고
    • Butorphanol: Characterization of agonist and antagonist effects in rhesus monkeys
    • BUTELMAN, E. R., WINGER, G., ZERNIG, G. AND WOODS, J. H.: Butorphanol: Characterization of agonist and antagonist effects in rhesus monkeys. J. Pharmacol. Exp. Ther. 272: 845-853, 1995.
    • (1995) J. Pharmacol. Exp. Ther. , vol.272 , pp. 845-853
    • Butelman, E.R.1    Winger, G.2    Zernig, G.3    Woods, J.H.4
  • 7
    • 0027452629 scopus 로고
    • The opioid receptor binding of dezocine, morphine, fentanyl, butorphanol and nalbuphine
    • CHEN, J.-C., SMITH, E. R., CAHILL, M., COHEN, R. AND FISHMAN, J. B.: The opioid receptor binding of dezocine, morphine, fentanyl, butorphanol and nalbuphine. Life Sci. 52: 389-396, 1992.
    • (1992) Life Sci. , vol.52 , pp. 389-396
    • Chen, J.-C.1    Smith, E.R.2    Cahill, M.3    Cohen, R.4    Fishman, J.B.5
  • 8
    • 0002261078 scopus 로고
    • A method for determining loss of pain sensation
    • D'AMOUR, F. E. AND SMITH, D. L.: A method for determining loss of pain sensation. J Pharmacol. Exp. Ther. 72: 74-79, 1941.
    • (1941) J Pharmacol. Exp. Ther. , vol.72 , pp. 74-79
    • D'Amour, F.E.1    Smith, D.L.2
  • 9
    • 15444359380 scopus 로고
    • Behavioral and pharmacological factors in opioid analgesia
    • ed. by L. S. Seiden and R. L. Balster, Alan R. Liss, New York
    • DYKSTRA, L. A.: Behavioral and pharmacological factors in opioid analgesia. In Behavioral Pharmacology: The Current Status, ed. by L. S. Seiden and R. L. Balster, pp. 111-129, Alan R. Liss, New York, 1985.
    • (1985) Behavioral Pharmacology: The Current Status , pp. 111-129
    • Dykstra, L.A.1
  • 10
    • 0025050786 scopus 로고
    • Butorphanol, levallorphan, nalbuphine and nalorphine as antagonists in the squirrel monkey
    • DYKSTRA, L. A.: Butorphanol, levallorphan, nalbuphine and nalorphine as antagonists in the squirrel monkey. J. Pharmacol. Exp. Ther. 254: 245-252, 1990.
    • (1990) J. Pharmacol. Exp. Ther. , vol.254 , pp. 245-252
    • Dykstra, L.A.1
  • 12
    • 0023637786 scopus 로고
    • Kappa opioids in rhesus monkeys. I. Diuresis, sedation, analgesia and discriminative stimulus effects
    • DYKSTRA, L. A., GMEREK, D. E., WINGER, G. AND WOODS, J. H.: Kappa opioids in rhesus monkeys. I. Diuresis, sedation, analgesia and discriminative stimulus effects. J. Pharmacol. Exp. Ther. 242: 413-420, 1987a.
    • (1987) J. Pharmacol. Exp. Ther. , vol.242 , pp. 413-420
    • Dykstra, L.A.1    Gmerek, D.E.2    Winger, G.3    Woods, J.H.4
  • 13
    • 0023626436 scopus 로고
    • Kappa opioids in rhesus monkeys. II. Analysis of the antagonistic actions of quadazocine and β-funaltrexamine
    • DYKSTRA, L. A., GMEREK, D. E., WINGER, G. AND WOODS, J. H.: Kappa opioids in rhesus monkeys. II. Analysis of the antagonistic actions of quadazocine and β-funaltrexamine. J. Pharmacol. Exp. Ther. 242: 421-427, 1987b.
    • (1987) J. Pharmacol. Exp. Ther. , vol.242 , pp. 421-427
    • Dykstra, L.A.1    Gmerek, D.E.2    Winger, G.3    Woods, J.H.4
  • 16
    • 0018870893 scopus 로고
    • Interactions between narcotic agonists, partial agonists and antagonists evaluated by schedule-controlled behavior
    • HARRIS, R. A.: Interactions between narcotic agonists, partial agonists and antagonists evaluated by schedule-controlled behavior. J. Pharmacol. Exp. Ther. 213: 497-503, 1980.
    • (1980) J. Pharmacol. Exp. Ther. , vol.213 , pp. 497-503
    • Harris, R.A.1
  • 17
    • 0025766286 scopus 로고
    • Differential antagonism of U69,593- and bremazocine-induced antinociception by (-)-UPHIT: Evidence for kappa opioid receptor multiplicity in mice
    • HORAN, P., DECOSTA, B. R., RICE, K. C. AND PORRECA, F.: Differential antagonism of U69,593-and bremazocine-induced antinociception by (-)-UPHIT: Evidence for kappa opioid receptor multiplicity in mice. J. Pharmacol. Exp. Ther. 257: 1154-1161, 1991.
    • (1991) J. Pharmacol. Exp. Ther. , vol.257 , pp. 1154-1161
    • Horan, P.1    Decosta, B.R.2    Rice, K.C.3    Porreca, F.4
  • 18
    • 0024789811 scopus 로고
    • Comparative pharmacological and biochemical studies between butorphanol and morphine
    • HORAN, P. J. AND HO, I. K: Comparative pharmacological and biochemical studies between butorphanol and morphine. Pharmacol. Biochem. Behav. 34: 847-854, 1989.
    • (1989) Pharmacol. Biochem. Behav. , vol.34 , pp. 847-854
    • Horan, P.J.1    Ho, I.K.2
  • 19
    • 0025944090 scopus 로고
    • The physical dependence liability of butorphanol: A comparative study with morphine
    • HORAN, P. J. AND HO, I. K.: The physical dependence liability of butorphanol: A comparative study with morphine. Eur. J. Pharmacol. 203: 387-391, 1991.
    • (1991) Eur. J. Pharmacol. , vol.203 , pp. 387-391
    • Horan, P.J.1    Ho, I.K.2
  • 20
    • 0018363404 scopus 로고
    • Analgesic effectiveness of the narcotic agonist-antagonists
    • HOUDE, R. W.: Analgesic effectiveness of the narcotic agonist-antagonists. Br. J. Clin. Pharmacol. 7: 297S-308S, 1979.
    • (1979) Br. J. Clin. Pharmacol. , vol.7
    • Houde, R.W.1
  • 22
    • 0028197263 scopus 로고
    • Epidural morphine with butorphanol in pediatric patients
    • LAWHORN, C. D. AND BROWN, R. E., JR.: Epidural morphine with butorphanol in pediatric patients. J. Clin. Anesth. 6: 91-94, 1994.
    • (1994) J. Clin. Anesth. , vol.6 , pp. 91-94
    • Lawhorn, C.D.1    Brown Jr., R.E.2
  • 23
    • 0025796796 scopus 로고
    • Epidural morphine with butorphanol for postoperative analgesia after cesarean delivery
    • LAWHORN, C. D., MCNITT, J. D., FIBUCH, E. E., JOYCE, J. T. AND LEADLEY, R. J., JR.: Epidural morphine with butorphanol for postoperative analgesia after cesarean delivery. Anesth. Analges. 72: 53-57, 1991.
    • (1991) Anesth. Analges. , vol.72 , pp. 53-57
    • Lawhorn, C.D.1    Mcnitt, J.D.2    Fibuch, E.E.3    Joyce, J.T.4    Leadley Jr., R.J.5
  • 24
    • 0020681060 scopus 로고
    • Evidence that nalorphine, butorphanol and oxilorphan are partial agonists at a κ-opioid receptor
    • LEANDER, J. D.: Evidence that nalorphine, butorphanol and oxilorphan are partial agonists at a κ-opioid receptor. Eur. J. Pharmacol. 86: 467-470, 1983a.
    • (1983) Eur. J. Pharmacol. , vol.86 , pp. 467-470
    • Leander, J.D.1
  • 25
    • 0020693721 scopus 로고
    • A kappa opioid effect: Increased urination in the rat
    • LEANDER, J. D.: A kappa opioid effect: Increased urination in the rat. J. Pharmacol. Exp. Ther. 224: 89-94, 1983b.
    • (1983) J. Pharmacol. Exp. Ther. , vol.224 , pp. 89-94
    • Leander, J.D.1
  • 26
    • 0023030720 scopus 로고
    • The contribution of intrinsic activity to the action of opioids in vitro
    • MILLER, L., SHAW, J. S. AND WHITING, E. M.: The contribution of intrinsic activity to the action of opioids in vitro. Br. J. Pharmacol. 87: 595-601, 1986.
    • (1986) Br. J. Pharmacol. , vol.87 , pp. 595-601
    • Miller, L.1    Shaw, J.S.2    Whiting, E.M.3
  • 27
    • 0029993262 scopus 로고    scopus 로고
    • Contribution of individual differences to discriminative stimulus, antinociceptive, and rate decreasing effects of opioids. Importance of the drugs intrinsic efficacy at the mu receptor
    • MORGAN, D. AND PICKER, M.: Contribution of individual differences to discriminative stimulus, antinociceptive, and rate decreasing effects of opioids. Importance of the drugs intrinsic efficacy at the mu receptor. Behav. Pharmacol. 7: 261-275, 1996.
    • (1996) Behav. Pharmacol. , vol.7 , pp. 261-275
    • Morgan, D.1    Picker, M.2
  • 28
    • 0027495926 scopus 로고
    • Effects of opioid agonists selective for mu, kappa and delta opioid receptors on schedule-controlled responding in rhesus monkeys: Antagonism by quadazocine
    • NEGUS, S. S., BURKE, T. F., MEDZIHRADSKY, F. AND WOODS, J. H.: Effects of opioid agonists selective for mu, kappa and delta opioid receptors on schedule-controlled responding in rhesus monkeys: Antagonism by quadazocine. J. Pharmacol. Exp. Ther. 267: 896-903, 1993.
    • (1993) J. Pharmacol. Exp. Ther. , vol.267 , pp. 896-903
    • Negus, S.S.1    Burke, T.F.2    Medzihradsky, F.3    Woods, J.H.4
  • 29
    • 0016671314 scopus 로고
    • Quantification of the analgesic activity of narcotic antagonists by a modified hot-plate procedure
    • O'CALLAGHAN, J. P. AND HOLTZMAN, S. G.: Quantification of the analgesic activity of narcotic antagonists by a modified hot-plate procedure. J. Pharmacol. Exp. Ther. 192: 497-505, 1975.
    • (1975) J. Pharmacol. Exp. Ther. , vol.192 , pp. 497-505
    • O'Callaghan, J.P.1    Holtzman, S.G.2
  • 30
    • 0025337573 scopus 로고
    • Butorphanol's efficacy at mu and kappa opioid receptors: Inferences based on schedule-controlled behavior of nontolerant and morphine-tolerant rats and on the responding of rate under a drug discrimination procedure
    • PICKER, M. J., NEGUS, S. S. AND CRAFT, R. M.: Butorphanol's efficacy at mu and kappa opioid receptors: Inferences based on schedule-controlled behavior of nontolerant and morphine-tolerant rats and on the responding of rate under a drug discrimination procedure. Pharmacol. Biochem. Behav. 36: 563-568, 1990.
    • (1990) Pharmacol. Biochem. Behav. , vol.36 , pp. 563-568
    • Picker, M.J.1    Negus, S.S.2    Craft, R.M.3
  • 31
    • 0030006381 scopus 로고    scopus 로고
    • Opioids and rate of positively reinforced behavior: Differential antagonism by naltrexone
    • PITTS, R. C., WEST, J. P., MORGAN, D., DYKSTRA, L. A. AND PICKER, M. J.: Opioids and rate of positively reinforced behavior: Differential antagonism by naltrexone. Behav. Pharmacol. 7: 205-215, 1996.
    • (1996) Behav. Pharmacol. , vol.7 , pp. 205-215
    • Pitts, R.C.1    West, J.P.2    Morgan, D.3    Dykstra, L.A.4    Picker, M.J.5
  • 32
    • 0021215268 scopus 로고
    • Roles of mu, delta and kappa opioid receptors in spinal and supraspinal mediation of gastrointestinal transit effects and hot-plate analgesia in the mouse
    • PORRECA, F., MOSBERG, H. I., HURST, R., HRUBY, V. J. AND BURKS, T. F.: Roles of mu, delta and kappa opioid receptors in spinal and supraspinal mediation of gastrointestinal transit effects and hot-plate analgesia in the mouse. J. Pharmacol. Exp. Ther. 230: 341-348, 1984.
    • (1984) J. Pharmacol. Exp. Ther. , vol.230 , pp. 341-348
    • Porreca, F.1    Mosberg, H.I.2    Hurst, R.3    Hruby, V.J.4    Burks, T.F.5
  • 33
    • 0023139286 scopus 로고
    • Binaltorphimine and nor-binaltorphimine: Potent and selective κ-opioid receptor antagonists
    • PORTOGHESE, P. S., LIPKOWSKI, A. W. AND TAKEMORI, A. E.: Binaltorphimine and nor-binaltorphimine: Potent and selective κ-opioid receptor antagonists. Life Sci. 40: 1287-1292, 1987.
    • (1987) Life Sci. , vol.40 , pp. 1287-1292
    • Portoghese, P.S.1    Lipkowski, A.W.2    Takemori, A.E.3
  • 34
    • 0023931559 scopus 로고
    • Naltrindole, a highly selective and potent non-peptide δ-opioid receptor antagonist
    • PORTOGHESE, P. S., SULTANA, M. AND TAKEMORI, A. E.: Naltrindole, a highly selective and potent non-peptide δ-opioid receptor antagonist. Eur. J. Pharmacol. 146: 185-186, 1988.
    • (1988) Eur. J. Pharmacol. , vol.146 , pp. 185-186
    • Portoghese, P.S.1    Sultana, M.2    Takemori, A.E.3
  • 35
    • 0027940660 scopus 로고
    • Drug discrimination assessment of agonist-antagonist opioids in humans: A three-choice saline-hydromorphonebutorphanol procedure
    • PRESTON, K. L. AND BIGELOW, G. E.: Drug discrimination assessment of agonist-antagonist opioids in humans: A three-choice saline-hydromorphonebutorphanol procedure. J. Pharmacol. Exp. Ther. 271: 48-60, 1994.
    • (1994) J. Pharmacol. Exp. Ther. , vol.271 , pp. 48-60
    • Preston, K.L.1    Bigelow, G.E.2
  • 36
    • 0020391631 scopus 로고
    • Important concepts of receptor theory
    • RUFFOLO, R. R.: Important concepts of receptor theory. J. Auton. Pharmacol. 2: 277-295, 1982.
    • (1982) J. Auton. Pharmacol. , vol.2 , pp. 277-295
    • Ruffolo, R.R.1
  • 37
    • 0021276596 scopus 로고
    • Morphine-like discriminative stimulus effects of buprenorphine and demethoxybuprenorphine in rats: Quantitative antagonism by naloxone
    • SHANNON, H. E., CONE, E. J. AND GORODETZKY, C. W.; Morphine-like discriminative stimulus effects of buprenorphine and demethoxybuprenorphine in rats: Quantitative antagonism by naloxone. J. Pharmacol. Exp. Ther. 229: 768-774, 1986.
    • (1986) J. Pharmacol. Exp. Ther. , vol.229 , pp. 768-774
    • Shannon, H.E.1    Cone, E.J.2    Gorodetzky, C.W.3
  • 39
    • 0028785534 scopus 로고
    • Examination of the kappa agonist and antagonist properties of opioids in the rat drug discrimination procedure: Influence of training dose and intrinsic efficacy
    • SMITH, M. A. AND PICKER, M. J.: Examination of the kappa agonist and antagonist properties of opioids in the rat drug discrimination procedure: Influence of training dose and intrinsic efficacy. Behav. Pharmacol. 6: 703-717, 1995.
    • (1995) Behav. Pharmacol. , vol.6 , pp. 703-717
    • Smith, M.A.1    Picker, M.J.2
  • 40
    • 0021769987 scopus 로고
    • Nonmedical use of butorphanol and diphenhydramine
    • SMITH, S. G. AND DAVIS, W. M.: Nonmedical use of butorphanol and diphenhydramine. JAMA 252: 1010, 1984.
    • (1984) JAMA , vol.252 , pp. 1010
    • Smith, S.G.1    Davis, W.M.2
  • 41
    • 0025815771 scopus 로고
    • Differential antagonism of delta opioid agonists by naltrindole and its benzofuran analog (NTB) in mice: Evidence for delta opioid receptor subtypes
    • SOFUOGLU, M., PORTOGHESE, P. S. AND TAKEMORI, A. E.: Differential antagonism of delta opioid agonists by naltrindole and its benzofuran analog (NTB) in mice: Evidence for delta opioid receptor subtypes. J. Pharmacol. Exp. Ther. 257: 676-680, 1991.
    • (1991) J. Pharmacol. Exp. Ther. , vol.257 , pp. 676-680
    • Sofuoglu, M.1    Portoghese, P.S.2    Takemori, A.E.3
  • 42
    • 0027949077 scopus 로고
    • Evidence that nor-binaltorphimine can function as an antagonist at multiple opioid receptor subtypes
    • SPANAGEL, R., ALMEIDA, O. F. X. AND SHIPPENBERG, T. S.: Evidence that nor-binaltorphimine can function as an antagonist at multiple opioid receptor subtypes. Eur. J. Pharmacol. 264: 157-162, 1994.
    • (1994) Eur. J. Pharmacol. , vol.264 , pp. 157-162
    • Spanagel, R.1    Almeida, O.F.X.2    Shippenberg, T.S.3
  • 43
    • 0015896090 scopus 로고
    • Determination of pharmacological constants: Use of narcotic antagonists to characterize analgesic receptors
    • Narcotic Antagonists, ed. by M. C. Braude, L. S. Harris, E. L. May, J. P. Smith and J. E. Villarreal. Raven Press, New York
    • TAKEMORI, A. E.: Determination of pharmacological constants: Use of narcotic antagonists to characterize analgesic receptors. In Narcotic Antagonists, ed. by M. C. Braude, L. S. Harris, E. L. May, J. P. Smith and J. E. Villarreal. Advances in Biochemical Psychopharmacology, Vol. 8, pp. 335-344, Raven Press, New York, 1974.
    • (1974) Advances in Biochemical Psychopharmacology , vol.8 , pp. 335-344
    • Takemori, A.E.1
  • 44
    • 0019427430 scopus 로고
    • The irreversible narcotic antagonistic and reversible agonistic properties of the fumaramate methyl ester derivative of naltrexone
    • TAKEMORI, A. E., LARSON, D. L. AND PORTOGHESE, P. S.: The irreversible narcotic antagonistic and reversible agonistic properties of the fumaramate methyl ester derivative of naltrexone. Eur. J. Pharmacol. 76: 445-451, 1981.
    • (1981) Eur. J. Pharmacol. , vol.76 , pp. 445-451
    • Takemori, A.E.1    Larson, D.L.2    Portoghese, P.S.3
  • 45
    • 0021137625 scopus 로고
    • Comparative antagonism by naltrexone and naloxone of μ, κ, and δ agonists
    • TAKEMORI, A. E. AND PORTOGHESE, P. S.: Comparative antagonism by naltrexone and naloxone of μ, κ, and δ agonists. Eur. J. Pharmacol. 104: 101-104, 1984.
    • (1984) Eur. J. Pharmacol. , vol.104 , pp. 101-104
    • Takemori, A.E.1    Portoghese, P.S.2
  • 46
    • 0023704417 scopus 로고
    • Respiratory effects of high-dose butorphanol
    • TALBERT, R. L., PETERS, J. I., SORRELS, S. C. AND SIMMONS, R. S.: Respiratory effects of high-dose butorphanol. Acute Care 12: (suppl. 1) 47-56, 1988.
    • (1988) Acute Care , vol.12 , Issue.1 SUPPL. , pp. 47-56
    • Talbert, R.L.1    Peters, J.I.2    Sorrels, S.C.3    Simmons, R.S.4
  • 47
    • 0018655874 scopus 로고
    • 2 and receptor differentiation: A statistical analysis of competitive antagonism
    • 2 and receptor differentiation: A statistical analysis of competitive antagonism. Life Sci. 25: 637-654, 1979.
    • (1979) Life Sci. , vol.25 , pp. 637-654
    • Tallarida, R.J.1    Cowan, A.2    Adler, M.W.3
  • 49
    • 0020080750 scopus 로고
    • Differentiation of potent μ-and κ-opiate agonists using heat and pressure antinociceptive profiles and combined potency analysis
    • UPTON, N., SEWELL, R. D. E. AND SPENCER, P. S. J.: Differentiation of potent μ-and κ-opiate agonists using heat and pressure antinociceptive profiles and combined potency analysis. Eur. J. Pharmacol. 78: 421-429, 1982.
    • (1982) Eur. J. Pharmacol. , vol.78 , pp. 421-429
    • Upton, N.1    Sewell, R.D.E.2    Spencer, P.S.J.3
  • 50
    • 0026144199 scopus 로고
    • Butorphanol tartrate (Stadol): A review
    • VOGELSANG, J. AND HAYES, S. R.: Butorphanol tartrate (Stadol): A review. J. Post Anesth. Nursing 6: 129-135, 1991.
    • (1991) J. Post Anesth. Nursing , vol.6 , pp. 129-135
    • Vogelsang, J.1    Hayes, S.R.2
  • 51
    • 0028172305 scopus 로고
    • 2 analysis for naltrexone antagonism of discriminative stimulus and analgesic effects of opiate agonists in rats
    • 2 analysis for naltrexone antagonism of discriminative stimulus and analgesic effects of opiate agonists in rats. J. Pharmacol. Exp. Ther. 271: 959-968, 1994.
    • (1994) J. Pharmacol. Exp. Ther. , vol.271 , pp. 959-968
    • Walker, E.A.1    Makhay, M.M.2    House, J.D.3    Young, A.M.4
  • 52
    • 0020051193 scopus 로고
    • Pharmacological characterization in vivo of the novel opiate, β-funaltrexamine
    • WARD, S. J., PORTOGHESE, P. S. AND TAKEMORI, A. E.: Pharmacological characterization in vivo of the novel opiate, β-funaltrexamine. J. Pharmacol. Exp. Ther. 220: 494-498, 1982.
    • (1982) J. Pharmacol. Exp. Ther. , vol.220 , pp. 494-498
    • Ward, S.J.1    Portoghese, P.S.2    Takemori, A.E.3
  • 53
    • 0020684011 scopus 로고
    • Relative involvement of mu, kappa and delta receptor mechanisms in opiate-mediated antinociception in mice
    • WARD, S. J. AND TAKEMORI, A. E.: Relative involvement of mu, kappa and delta receptor mechanisms in opiate-mediated antinociception in mice. J. Pharmacol. Exp. Ther. 224: 525-530, 1983.
    • (1983) J. Pharmacol. Exp. Ther. , vol.224 , pp. 525-530
    • Ward, S.J.1    Takemori, A.E.2
  • 54
    • 0022468256 scopus 로고
    • Quantitative analysis of naloxone antagonism of the discriminative stimulus properties of morphine in the pigeon
    • WESSINGER, W. D. AND MCMILLAN, D. E.: Quantitative analysis of naloxone antagonism of the discriminative stimulus properties of morphine in the pigeon. Pharmacol. Biochem. Behav. 25: 209-214, 1986.
    • (1986) Pharmacol. Biochem. Behav. , vol.25 , pp. 209-214
    • Wessinger, W.D.1    Mcmillan, D.E.2
  • 55
    • 0026769789 scopus 로고
    • Discriminative stimulus effects of morphine: Effects of training dose on agonist and antagonist effects of mu opioids
    • YOUNG, A. M., MASAKI, M. A. AND GEULA, C.: Discriminative stimulus effects of morphine: Effects of training dose on agonist and antagonist effects of mu opioids. J. Pharmacol. Exp. Ther. 261: 246-257, 1992.
    • (1992) J. Pharmacol. Exp. Ther. , vol.261 , pp. 246-257
    • Young, A.M.1    Masaki, M.A.2    Geula, C.3
  • 56
    • 0023234142 scopus 로고
    • Use of β-funaltrexamine to determine mu opioid receptor involvement in the analgesic activity of various opioid ligands
    • ZIMMERMAN, D. M., LEANDER, J. D., REEL, J. K. AND HYNES, M. D.: Use of β-funaltrexamine to determine mu opioid receptor involvement in the analgesic activity of various opioid ligands. J. Pharmacol. Exp. Ther. 241: 374-378, 1987.
    • (1987) J. Pharmacol. Exp. Ther. , vol.241 , pp. 374-378
    • Zimmerman, D.M.1    Leander, J.D.2    Reel, J.K.3    Hynes, M.D.4


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