Prevalence of Type II diabetes mellitus and insulin resistance in parents of women with polycystic ovary syndrome

Diabetologia

Volumn 45, Issue 7, 2002, Pages 959-964

  Sir Petermann, T ^a   Angel, B ^b   Maliqueo, M ^b   Carvajal, F ^b   Santos, J ^b   Perez Bravo F ^b  

^a UNIVERSITY OF CHILE   (Chile)

^b UNIVERSITY OF CHILE   (Chile)

Author keywords

Family study; Insulin resistance; Polycystic ovary syndrome; Type II diabetes

Indexed keywords

C PEPTIDE; INSULIN; SEX HORMONE BINDING GLOBULIN;

ADULT; ARTICLE; BODY MASS; CLINICAL FEATURE; COHORT ANALYSIS; CONTROLLED STUDY; FEMALE; GLUCOSE BLOOD LEVEL; GLUCOSE TOLERANCE; HIGH RISK POPULATION; HUMAN; INSULIN BLOOD LEVEL; INSULIN RESISTANCE; MAJOR CLINICAL STUDY; METABOLIC DISORDER; METABOLIC PARAMETERS; NON INSULIN DEPENDENT DIABETES MELLITUS; ORAL GLUCOSE TOLERANCE TEST; OVARY POLYCYSTIC DISEASE; PRIORITY JOURNAL; WORLD HEALTH ORGANIZATION; ADOLESCENT; BLOOD; BODY CONSTITUTION; FATHER; GENETICS; GLUCOSE TOLERANCE TEST; MALE; METABOLISM; MOTHER; PREVALENCE; REFERENCE VALUE;

ADOLESCENT; ADULT; BLOOD GLUCOSE; BODY CONSTITUTION; DIABETES MELLITUS, NON-INSULIN-DEPENDENT; FATHERS; FEMALE; GLUCOSE TOLERANCE TEST; HUMAN; INSULIN; INSULIN RESISTANCE; MALE; MOTHERS; POLYCYSTIC OVARY SYNDROME; PREVALENCE; REFERENCE VALUES; SUPPORT, NON-U.S. GOV'T; DIABETES MELLITUS, TYPE 2; HUMANS;

EID: 0036020279     PISSN: 0012186X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00125-002-0836-3     Document Type: Article

References (47)

1. Epidemiology of infertility and polycystic ovarian disease: Endocrinological and demographic studies
2. Polycystic ovary syndrome as a form of functional ovarian hyperandrogenism due to dysregulation of androgen secretion
3. Polycystic ovary syndrome
4. Prevalence of the polycystic ovary syndrome in unselected black and white women of the southeastern United States: A prospective study
5. Diagnostic criteria for polycystic ovary syndrome: Towards a rational approach
6. Disturbances in insulin secretion and sensitivity in women with the polycystic ovary syndrome
7. Characterization of groups of hyperandrogenic women with acanthosis nigricans, impaired glucose tolerance, and/or hyperinsulinemia
8. Profound peripheral insulin resistance, independent of obesity, in polycystic ovary syndrome
9. Insulin resistance and the polycystic ovary syndrome: Mechanism and implications for pathogenesis
10. Prevalence of impaired glucose tolerance and diabetes in women with polycystic ovary syndrome
11. Prevalence and predictors of risk for Type II diabetes mellitus and impaired glucose tolerance in polycystic ovary syndrome: A prospective, controlled study in 254 affected women
12. Defects in beta-cell function in functional ovarian hyperandrogenism
13. Insulin secretory defects in polycystic ovary syndrome. Relationship to insulin sensitivity and family history of non-insulin-dependent diabetes mellitus
14. Obesity and glucose intolerance in androgen excess
15. Polycystic ovary syndrome (PCOS): Arguably the most common endocrinopathy is associated with significant morbidity in women
16. Hereditary factors in the Stein-Leventhal syndrome
17. Polycystic ovarian disease: Heritability and heterogeneity
18. Phenotype and genotype in polycystic ovary syndrome
19. The genetic basis of polycystic ovary syndrome
20. Familial clustering in the polycystic ovarian syndrome
21. Genetic dissection of complex traits
22. A twin study of polycystic ovary syndrome
23. Evidence for a single gene effect causing polycystic ovaries and male pattern baldness
24. Evidence for a genetic basis for hyperandrogenemia in polycystic ovary syndrome
25. Hyperinsulinemia is common in family members of women with polycystic ovary syndrome
26. Heritability of insulin secretion and insulin action in women with polycystic ovary syndrome and their first degree relatives
27. Prevalence of metabolic disorders among family members of patients with polycystic ovary syndrome
28. Migraine and depression: Association and familial transmission
29. Do hyperandrogenic women with normal menses have polycystic ovary syndrome?
30. Homeostasis model assessment: Insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man
31. Insulin sensitivity indices obtained from oral glucose tolerance testing: Comparison with the euglycemic insulin clamp
32. Defining the genetic contribution of Type II diabetes mellitus
33. Heritability of pancreatic β- cell function among nondiabetic members of caucasian familial Type II diabetic kindreds
34. Diabetes prevalence and risk factors in polycystic ovary syndrome
35. Impaired glucose tolerance-prevalence and conversion to NIDDM
36. Regulation of sex hormone binding globulin (SHBG) production in Hep G2 cells by insulin
37. Pathophysiology of sex hormone binding globulin (SHBG): Relation to insulin
38. A direct effect of hyperinsulinemia on serum sex hormone-binding globulin levels in obese women with polycystic ovary syndrome
39. Response of sex hormone binding globulin and insulin-like growth factor binding protein-1 to an oral glucose tolerance test in obese women with polycystic ovary syndrome before and after calorie restriction
40. Low Sex-Hormone-Binding Globulin concentration as independent risk factor for development of NIDDM
41. The development of the polycystic ovary syndrome: Family history as a risk factor
42. Prevalence of polycystic ovary syndrome (PCOS) in first-degree relatives of patients with PCOS
43. Male pattern baldness is not associated with established cardiovascular risk factors in the general population
44. Polycystic ovaries are inherited as an autosomal dominant trait: Analysis of 29 polycystic ovary syndrome and 10 control families
45. Early androgenic alopecia as a marker of insulin resistance
46. Screening for diabetes in general practice: Cross sectional population study