The role of prostaglandin E2 in the immunopathogenesis of experimental pulmonary tuberculosis

Immunology

Volumn 106, Issue 2, 2002, Pages 257-266

  Moreno, Javier Rangel ^b   García, Iris Estrada ^b   De La Luz García Hernández, María ^a   Leon, Diana Aguilar ^a   Marquez, Ricardo ^a   Pando, Rogelio Hernández ^a  

^a INSTITUTO NACIONAL DE CIENCIAS MÉDICAS Y NUTRICIÓN SALVADOR ZUBIRÁN   (Mexico)

^b INSTITUTO POLITÉCNICO NACIONAL   (Mexico)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLOOXYGENASE 2 INHIBITOR; GAMMA INTERFERON; INTERLEUKIN 1ALPHA; NIFLUMIC ACID; NITRIC OXIDE SYNTHASE; PROSTAGLANDIN E2; TUMOR NECROSIS FACTOR ALPHA; CYCLOOXYGENASE 1; CYCLOOXYGENASE 2; CYTOKINE; ISOENZYME; MEMBRANE PROTEIN; PROSTAGLANDIN SYNTHASE; PROSTAGLANDIN SYNTHASE INHIBITOR; PTGS1 PROTEIN, MOUSE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BACTERIAL GROWTH; CELLULAR IMMUNITY; CONTROLLED STUDY; DISEASE COURSE; GRANULOMA; IMMUNOHISTOCHEMISTRY; IMMUNOPATHOGENESIS; LUNG TUBERCULOSIS; MACROPHAGE ACTIVATION; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROSTAGLANDIN SYNTHESIS; PROTEIN EXPRESSION; ANIMAL; BAGG ALBINO MOUSE; BIOSYNTHESIS; DRUG ANTAGONISM; ENZYME LINKED IMMUNOSORBENT ASSAY; GENE EXPRESSION; GENETICS; IMMUNOLOGY; METABOLISM; PATHOLOGY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

ANIMALS; CYCLOOXYGENASE 1; CYCLOOXYGENASE 2; CYCLOOXYGENASE 2 INHIBITORS; CYCLOOXYGENASE INHIBITORS; CYTOKINES; DINOPROSTONE; DISEASE PROGRESSION; ENZYME-LINKED IMMUNOSORBENT ASSAY; GENE EXPRESSION; ISOENZYMES; MALE; MEMBRANE PROTEINS; MICE; MICE, INBRED BALB C; NIFLUMIC ACID; PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; TUBERCULOSIS, PULMONARY;

EID: 0036016998     PISSN: 00192805     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2567.2002.01403.x     Document Type: Article

References (29)

1. Lipid mediator networks in cell signaling: Update and impact of cytokines
2. A new view of prostaglandin E regulation of the immune response
3. Biochemistry of prostaglandin endoperoxidase H synthases (cyclooxygenases 1 and 2)
4. Induction of cyclooxygenase by interleukin 1 alpha
5. Synergistic and overlapping activities of tumor necrosis factor-α and IL-1
6. Lipopolysacharide induces prostaglandin H synthase-2 protein and mRNA in human alveolar macrophages and blood monocytes
7. Chronic infection due to Mycobacterium intracellulare in mice association with macrophage release of prostaglandin E2 and reversal by injection of indomethacin, muramyl dipeptide, or interferon-γ
8. Cyclic AMP as a mediator of prostaglandin E induced suppression of human natural killer cell activity
9. Prostaglandins modulate macrophage Ia expression
10. Prostaglandin E2 inhibits production of Th-1 lymphokines but not of Th-2 lymphokines
11. Prostaglandin E2 and dexamethasone inhibit IL-12 receptor expression and IL-12 responsiveness
12. Prostaglandin-E2 is a potent inhibitor of human interleukin 12 production
13. Sensitivity difference to the suppressive effect of prostaglandin E2 among mouse strains: A possible mechanism to polarize Th2 type response in BALB/c mice
14. Regulation of macrophage tumoricidal function: A role of prostaglandins of the E series
15. Release of tumor necrosis factor-α from macrophages. Enhancement and suppression are dose-dependently regulated by prostaglandin E2 and cyclic nucleotides
16. The pathogenesis of tuberculosis
17. Killing of virulent Mycobacterium tuberculosis by reactive nitrogen intermediates produced by activated macrophages
18. Type 2 cytokine gene activation and its relationship to extent of disease in patients with tuberculosis
19. Contribution of Th1 and Th2 cells to protection and pathology in experimental models of granulomatous disease
20. Correlation between kinetics of Th1/Th2 cells and pathology in a murine model of experimental pulmonary tuberculosis
21. Analysis of the local kinetics and localization of interleukin 1α, tumor necrosis factor α and transforming growth factor β during the course of experimental pulmonary tuberculosis
22. Interactions between hormone-mediated and vaccine mediated immunotherapy for pulmonary tuberculosis in BALB/c mice
23. Reagent for the single step simultaneous isolation of RNA, DNA and proteins from cells and tissue samples
24. Expression of nitric oxide synthase and nitro-tyrosine during the evolution of experimental pulmonary tuberculosis
25. T cell interleukin 17 induces stromal cells to produce proinflammatory and hematopoietic cytokines
26. 2 regulates inducible nitric oxide synthase in the murine macrophage cell line J774
27. MAP kinase pathways as a route for regulatory mechanisms of IL-10 and IL-4 which inhibit COX-2 expression in human monocytes
28. Differential sensitivities of human blood monocytes and alveolar macrophages to the inhibition of prostaglandin endoperoxide synthase 2 by interleukin 4
29. Essential fatty acids and immune response