Early mitochondrial dysfunction, superoxide anion production, and DNA degradation are associated with non-apoptotic death of human airway epithelial cells induced by Pseudomonas aeruginosa exotoxin A

American Journal of Respiratory Cell and Molecular Biology

Volumn 26, Issue 5, 2002, Pages 617-626

  Plotkowski, Maria Cristina ^a   Póvoa, Helvécio C C ^a   Zahm, Jean Marie ^a   Lizard, Gérard ^a   Pereira, Geraldo M B ^a   Tournier, Jean Marie ^a   Puchelle, Edith ^a  

^a STATE UNIVERSITY OF RIO DE JANEIRO   (Brazil)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIA (MICROORGANISMS); PSEUDOMONAS; PSEUDOMONAS AERUGINOSA;

BACTERIAL TOXIN; CASPASE; DNA; DNA FRAGMENT; ENZYME INHIBITOR; EXOTOXIN; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; SUPEROXIDE; TOXA PROTEIN, PSEUDOMONAS AERUGINOSA; VIRULENCE FACTOR;

APOPTOSIS; ARTICLE; BRONCHUS; CELL CULTURE; CELL DEATH; CELL MEMBRANE POTENTIAL; CELL SURVIVAL; DOSE RESPONSE; DRUG ANTAGONISM; DRUG EFFECT; EPITHELIUM CELL; HUMAN; INTRACELLULAR MEMBRANE; METABOLISM; MITOCHONDRION; NECROSIS; NOSE POLYP; PATHOLOGY; RESPIRATORY TRACT MUCOSA; ULTRASTRUCTURE;

ADP RIBOSE TRANSFERASES; APOPTOSIS; BACTERIAL TOXINS; BRONCHI; CASPASES; CELL DEATH; CELL SURVIVAL; CELLS, CULTURED; DNA; DNA FRAGMENTATION; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME INHIBITORS; EPITHELIAL CELLS; EXOTOXINS; HUMANS; INTRACELLULAR MEMBRANES; MEMBRANE POTENTIALS; MITOCHONDRIA; NASAL POLYPS; NECROSIS; RESPIRATORY MUCOSA; SUPEROXIDES; VIRULENCE FACTORS;

EID: 0036010529     PISSN: 10441549     EISSN: None     Source Type: Journal    
DOI: 10.1165/ajrcmb.26.5.4489     Document Type: Article

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