Immunomodulatory effect of oxygen and pressure

Comparative Biochemistry and Physiology - A Molecular and Integrative Physiology

Volumn 132, Issue 1, 2002, Pages 193-197

  Van Den Blink, B ^a   Van Der Kleij, A J ^b   Versteeg, H H ^a   Peppelenbosch, M P ^a  

^a ACADEMIC MEDICAL CENTER   (Netherlands)

^b UNIVERSITY OF AMSTERDAM   (Netherlands)

Author keywords

Cytokines; Hyperbaric oxygenation; Lipopolysaccharides, Cell signaling; Macrophages; P38 MAP kinase; p42 44 MAP kinase; PD98059; SB203580

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; CYTOKINE; LIPOPOLYSACCHARIDE; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; OXYGEN; PROTEIN P42; PROTEIN P44; SYNAPTOPHYSIN; DIMETHYL SULFOXIDE; ENZYME INHIBITOR; FLAVONOID; IMIDAZOLE DERIVATIVE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE P38; PYRIDINE DERIVATIVE; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ATMOSPHERIC PRESSURE; CELL STIMULATION; CONFERENCE PAPER; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; DRUG EFFECT; HYPERBARIC OXYGEN; HYPERBARISM; HYPEROXIA; IMMUNOMODULATION; MACROPHAGE; MOUSE; NONHUMAN; OXYGEN TENSION; PRESSURE; ANIMAL; ARTICLE; CELL CULTURE; DRUG ANTAGONISM; ENZYMOLOGY; IMMUNOLOGY; METABOLISM;

MURINAE;

ANIMALS; CELLS, CULTURED; DIMETHYL SULFOXIDE; ENZYME INHIBITORS; FLAVONOIDS; HYPERBARIC OXYGENATION; IMIDAZOLES; LIPOPOLYSACCHARIDES; MACROPHAGES; MICE; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASES; OXYGEN; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PYRIDINES; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0036010232     PISSN: 10956433     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1095-6433(01)00547-5     Document Type: Conference Paper

References (16)

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3. The p38/RK mitogen-activated protein kinase pathway regulates interleukin-6 synthesis response to tumor necrosis factor
4. Both Erk and p38 kinases are necessary for cytokine gene transcription
5. SB 203580 is a specific inhibitor of a MAP kinase homologue, which is stimulated by cellular stresses and interleukin-1
6. Microgravity decreases c-fos induction and serum response element activity
7. Macrophages induce cellular immunity by activating Th1 cell responses and suppressing Th2 cell responses
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13. Pro-inflammatory cytokines and environmental stress cause p38 mitogen-activated protein kinase activation by dual phosphorylation on tyrosine and threonine
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15. p38 mitogen-activated protein kinase inhibition increases cytokine release by macrophages in vitro and during infection in vivo
16. Phospholipase A2 inhibitors and leukotriene synthesis inhibitors block TNF-induced NF-kappaB activation