Phospholipase A2 inhibitors and leukotriene synthesis inhibitors block TNF-induced NF-κB activation

Cytokine

Volumn 11, Issue 2, 1999, Pages 104-110

  Van Puijenbroek, André A F L ^a,c   Wissink, Sacha ^a   Van der Saag, Paul T ^a   Peppelenbosch, Maikel P ^a,b  

^a HUBRECHT INSTITUTE   (Netherlands)

^b ACADEMIC MEDICAL CENTER   (Netherlands)

^c NETHERLANDS CANCER INSTITUTE   (Netherlands)

Author keywords

5 Lipoxygenase; Arachidonic acid; NF B; Phospholipase A2; Tumour necrosis factor

Indexed keywords

3 [3 TERT BUTYLTHIO 1 (4 CHLOROBENZYL) 5 ISOPROPYL 2 INDOLYL] 2,2 DIMETHYLPROPIONIC ACID; 4 BROMOPHENACYL BROMIDE; ARACHIDONIC ACID; LEUKOTRIENE; LIPOXYGENASE INHIBITOR; LYMPHOTOXIN; NORDIHYDROGUAIARETIC ACID; PHOSPHOLIPASE A2 INHIBITOR; TUMOR NECROSIS FACTOR; TUMOR NECROSIS FACTOR RECEPTOR; 4-BROMOPHENACYL BROMIDE; 5-LIPOXYGENASE-ACTIVATING PROTEIN; ACETOPHENONE DERIVATIVE; ARACHIDONATE 5 LIPOXYGENASE; ARACHIDONATE 5 LIPOXYGENASE ACTIVATING PROTEIN; CARRIER PROTEIN; ENZYME INHIBITOR; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDOLE DERIVATIVE; LEUKOTRIENE RECEPTOR BLOCKING AGENT; MEMBRANE PROTEIN; PHOSPHOLIPASE A; TUMOR NECROSIS FACTOR ALPHA;

ARACHIDONIC ACID METABOLISM; ARTICLE; CELL CULTURE; DNA BINDING; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROMOTER REGION; PROTO ONCOGENE; SIGNAL TRANSDUCTION; TRANSACTIVATION; CELL LINE; DRUG ANTAGONISM; DRUG EFFECT; LEUKEMIA CELL LINE; METABOLISM;

ACETOPHENONES; ARACHIDONATE 5-LIPOXYGENASE; ARACHIDONIC ACID; CARRIER PROTEINS; CELL LINE; ENZYME INHIBITORS; HUMANS; INDOLES; JURKAT CELLS; LEUKOTRIENE ANTAGONISTS; LIPOXYGENASE INHIBITORS; MEMBRANE PROTEINS; NF-KAPPA B; NORDIHYDROGUAIARETIC ACID; PHOSPHOLIPASES A; TRANSCRIPTION, GENETIC; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0033068161     PISSN: 10434666     EISSN: None     Source Type: Journal    
DOI: 10.1006/cyto.1998.0404     Document Type: Article

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