Integrin αvβ1 is a receptor for Foot-and-mouth disease virus

Journal of Virology

Volumn 76, Issue 3, 2002, Pages 935-941

  Jackson, Terry ^a   Mould, A Paul ^a   Sheppard, Dean ^a   King, Andrew M Q ^a  

^a INSTITUTE FOR ANIMAL HEALTH   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA5 BETA1 INTEGRIN RECEPTOR; ALPHA5 INTEGRIN; AMINO ACID; BETA1 INTEGRIN; DIMER; INTEGRIN RECEPTOR; LIGAND; UNCLASSIFIED DRUG; ALPHAVBETA5 INTEGRIN; ALPHAVBETA6 INTEGRIN; ARGINYL-GLYCYL-ASPARTIC ACID; ARGINYLGLYCYLASPARTIC ACID; CALCIUM; CAPSID PROTEIN; CD51 ANTIGEN; DIVALENT CATION; FIBRONECTIN RECEPTOR; INTEGRIN; INTEGRIN ALPHAVBETA1; LEUKOCYTE ANTIGEN; MAGNESIUM; MANGANESE; OLIGOPEPTIDE; TUMOR ANTIGEN; VIRUS RECEPTOR; VITRONECTIN RECEPTOR; VP1 PROTEIN, FOOT AND MOUTH DISEASE VIRUS; VP1 PROTEIN, FOOT-AND-MOUTH DISEASE VIRUS;

AMINO ACID SEQUENCE; ANIMAL CELL; ARTICLE; BINDING AFFINITY; BINDING SITE; CHIMERA; CHO CELL; CONCENTRATION RESPONSE; CONTROLLED STUDY; FOOT AND MOUTH DISEASE; FOOT AND MOUTH DISEASE VIRUS; LIGAND BINDING; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN MOTIF; SEQUENCE ANALYSIS; VIRUS CELL INTERACTION; ANIMAL; CELL LINE; GENETICS; HAMSTER; HUMAN; METABOLISM; VIRUS CAPSID;

ANIMALS; ANTIGENS, CD; ANTIGENS, CD29; ANTIGENS, NEOPLASM; CALCIUM; CAPSID; CAPSID PROTEINS; CATIONS, DIVALENT; CELL LINE; CHO CELLS; CRICETINAE; FOOT-AND-MOUTH DISEASE VIRUS; HUMANS; INTEGRIN ALPHAV; INTEGRINS; MAGNESIUM; MANGANESE; OLIGOPEPTIDES; RECEPTORS, FIBRONECTIN; RECEPTORS, VIRUS; RECEPTORS, VITRONECTIN;

EID: 0036007134     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/JVI.76.3.935-941.2002     Document Type: Article

References (61)

1. The early pathogenesis of foot-and-mouth disease virus in pigs infected by contact: A quantitative time-course study using TaqMan RT-PCR
2. Monoclonal antibody 9EG7 defines a novel β1 integrin epitope induced by soluble ligand and manganese, but inhibited by calcium
3. Distinctive features of foot-and-mouth disease virus, a member of the picornavirus family: Aspects of virus protein synthesis, protein processing and structure
4. Antibodies to the vitronectin receptor (integrin αvβ3) inhibit binding and infection of foot-and-mouth disease virus to cultured cells
5. The integrin β1 subunit associates with the vitronectin receptor αv subunit to form a novel vitronectin receptor in a human embryonic kidney cell line
6. Expression of the β6 integrin subunit in development, neoplasia and tissue repair suggests a role in epithelial remodelling
7. Restricted distribution of integrin β6 messenger RNA in primate epithelial tissues
8. A pathogenesis study of foot-and-mouth disease virus in cattle, using in situ hybridisation
9. A preliminary study of the pathogenesis of foot-and-mouth disease virus, using in situ hybridisation
10. The pathogenesis of natural and stimulated natural foot-and-mouth disease virus infection in cattle
11. Perturbations in the surface structure of A22 Iraq foot-and-mouth disease virus accompanying coupled changes in host cell specificity and antigenicity
12. Distribution of integrin cell adhesion receptors in normal and malignant lung tissue
13. Integrin α5β1-mediated adenovirus infection is enhanced by the integrin-activating antibody TS2/16
14. Integrin cytoplasmic interactions and bidirectional transmembrane signalling
15. The structure and function of a foot-and-mouth disease virus-oligosaccharide receptor complex
16. Integrin signalling
17. Keratinocytes in human wounds express alpha v beta 6 integrin
18. A biochemical characterization of the binding of osteopontin to integrins αvβ1 and αvβ5
19. Suppression of integrin activation: A novel function of a Ras/Raf-initiated MAP kinase pathway
20. Integrins: Versatility, modulation, and signaling in cell adhesion
21. Efficient infection of cells in culture by type O foot-and mouth disease virus requires binding to cell surface heparan sulfate
22. Foot-and mouth disease virus is a ligand for the high-affinity binding conformation of integrin α5β1: Influence of the leucine residue within the RGDL motif on selectivity of integrin binding
23. Arginine-glycine-aspartic acid-specific binding by foot-and-mouth disease virus to the purified integrin αvβ3 in vitro
24. The epithelial integrin αvβ6 is a receptor for foot-and-mouth disease virus
25. Calcium as a potential physiological regulator of integrin-mediated cell adhesion
26. Definition of an unexpected ligand recognition motif for αvβ6 integrin
27. Two conformations of the integrin A-domain (I-domain): A pathway for activation?
28. Integrin αvβ1 is an adenovirus coreceptor
29. 2+-complexed crystal structures
30. Structure of a major immunogenic site on foot-and-mouth disease virus
31. αvβ1 is a receptor for vitronectin and fibronectin, and acts with α5β1 to mediate spreading on fibronectin
32. Antibody-complexed foot-and-mouth disease virus, but not poliovirus, can infect cells via the Fc receptor
33. RGD sequence of foot-and-mouth disease virus is essential for infecting cells via the natural receptor but can be bypassed by an antibody-dependent enhancement pathway
34. Evidence for at least 4 antigenic sites on type foot-and-mouth disease virus involved in neutralization; identification by single and multiple monoclonal antibody-resistant mutants
35. Distribution of integrin cell adhesion receptors in normal bronchial epithelial cells and lung cancer cells in vitro and in vivo
36. Role of the cytoplasmic domain of the β-subunit of integrin αvβ6 in infection by foot-and mouth disease virus
37. Regulation of integrin α5β1-fibronectin interactions by divalent cations
38. 2-terminal repeats of the a subunit
39. Identification of a novel anti-integrin monoclonal antibody that recognises a ligand-induced binding site epitope on the β1 subunit
40. Interactions between growth factors and integrins: Latent forms of transforming growth factor-β are ligands for the integrin αvβ1
41. The integrin αvβ6 binds and activates latent TGFβ1: A mechanism for regulating pulmonary inflammation and fibrosis
42. Foot-and-mouth disease virus virulent for cattle utilizes the integrin αvβ3 as its receptor
43. Integrin αvβ3 (vitronectin receptor) is a candidate receptor for the virulent echovirus 9 strain Barty
44. Cell-surface interactions of echovirus 22
45. Entry of coxsackievirus A9 into host cells: Specific interactions with αvβ3 integrin, the vitronectin receptor
46. Tissue culture adaption of foot-and-mouth disease virus selects viruses that bind to heparin and are attenuated in cattle
47. Persistent infection with foot-and-mouth disease virus
48. Isolation and characterization of Chinese hamster ovary cell variants deficient in the expression of the fibronectin receptor
49. Transforming growth factor β differentially regulates expression of integrin subunits in a guinea pig airway epithelial cells
50. Adhesion receptors of the immune system
51. Changing ligand binding specificities of αvβ1 and αvβ3 integrins by swapping a short diverse sequence of the β subunit
52. Human parechovirus 1 utilizes integrin αvβ3 and αvβ1 as receptors
53. A novel fibronectin receptor with an unexpected subunit composition (αvβ1)
54. Role of the integrin αvβ6 in cell attachment to fibronectin
55. Integrins αvβ3 and αvβ5 promote adenovirus internalization but not virus attachment
56. Integrin αvβ5 selectively promotes adenovirus mediated cell membrane permeabilization
57. Neutralization of foot-and-mouth disease virus can be mediated through any of at least three antigenic sites
58. Crystal structure of the extracellular segment of integrin αvβ3
59. The localization of persistent foot-and-mouth disease virus in the epithelial cells of the soft palate and pharynx
60. The αvβ1 integrin functions as a fibronectin receptor but does not support fibronectin matrix assembly and cell migration on fibronectin
61. Integrin activation by R-ras