Iron metabolism in insects

Annual Review of Entomology

Volumn 47, Issue , 2002, Pages 535-559

  Nichol, Helen ^a   Law, John H ^a   Winzerling, Joy J ^a  

^a UNIVERSITY OF ARIZONA   (United States)

Author keywords

Ferritin; Insect; Iron; Iron regulatory protein; Transferrin

Indexed keywords

INSECT; IRON; METABOLISM;

DROSOPHILA MELANOGASTER; HEXAPODA; INSECTA; MELANOGASTER; VERTEBRATA;

FERRITIN; INSECT PROTEIN; IRON;

AMINO ACID SEQUENCE; ANIMAL; BIOSYNTHESIS; DROSOPHILA MELANOGASTER; GENE; GENETIC TRANSCRIPTION; GENETICS; HUMAN; INSECT; METABOLISM; MOLECULAR GENETICS; REVIEW; RNA TRANSLATION; TRANSPORT AT THE CELLULAR LEVEL;

AMINO ACID SEQUENCE; ANIMAL; BIOLOGICAL TRANSPORT; DROSOPHILA MELANOGASTER; FERRITIN; GENES, INSECT; HUMAN; INSECT PROTEINS; INSECTS; IRON; MOLECULAR SEQUENCE DATA; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, NON-P.H.S.; SUPPORT, U.S. GOV'T, P.H.S.; TRANSCRIPTION, GENETIC; TRANSLATION, GENETIC;

EID: 0036006842     PISSN: 00664170     EISSN: None     Source Type: Book Series    
DOI: 10.1146/annurev.ento.47.091201.145237     Document Type: Review

References (129)

1. The genome sequence of Drosophila melanogaster
2. Post-transcriptional regulation of H-ferritin mRNA
3. Transferrin, the transferrin receptor, and the uptake of iron by cells
4. Iron transport across biologic membranes
5. Structure, function, and evolution of ferritins
6. Isolation and molecular cloning of transferrin from the tobacco hornworm, Manduca sexta
7. Aconitase as iron-sulfur protein, enzyme, and iron-regulatory protein
8. Identification and isolation of a 45-kDa calcium-dependent lactoferrin receptor from rat hepatocytes
9. Structural and functional relationships of human ferritin H and L chains deduced from cDNA clones
10. Multiple mechanisms of iron-induced ferritin synthesis in HeLa cells
11. Friedreich's ataxia: Autosomal recessive disease caused by an intronic GAA triplet repeat expansion
12. Musca domestica hemolymph ferritin
13. Iron-responsive elements: Regulatory RNA sequences that control mRNA levels and translation
14. Isolation and properties of Drosophila melanogaster ferritin: Molecular cloning of a cDNA that encodes one subunit, and localization of the gene on the third chromosome
15. Thyrotropin and adenosine 3′,5′-monophosphate stimulate the activity of the ferritin-H promoter
16. Transcriptional regulation of ferritin H messenger RNA levels in FRTL rat thyroid cells by thyrotropin
17. Characterization of a ferritin isolated from the midgut epithelial cells of a homopteran insect, Philaenus spumarius L
18. Sialic acid and the microheterogeneity of human serum ferritin
19. Finding the hairpin in the haystack: Searching for RNA motifs
20. Differences in the regulation of messenger RNA for housekeeping and specialized-cell ferritin. A comparison of three distinct ferritin complementary DNAs, the corresponding subunits, and identification of the first processed in amphibia
21. Multiple red cell ferritin mRNAs, which code for an abundant protein in the embryonic cell type, analyzed by cDNA sequence and by primer extension of the 5′-untranslated regions
22. Ferritins of Schistosoma mansoni: Sequence comparison and expression in female and male worms
23. Positional cloning of zebrafish ferroportin1 identifies a conserved vertebrate iron exporter
24. Ferritin acts as the most abundant binding protein for snowdrop lectin in the midgut of rice brown planthoppers (Nilaparvata lugens)
25. Organization of the ferritin genes in Drosophila melanogaster
26. Isolation and characterization of mosquito ferritin and cloning of a cDNA that encodes one subunit
27. Iron regulatory proteins, iron responsive elements and iron homeostasis
28. A novel MHC class I-like gene is mutated in patients with hereditary haemochromatosis
29. Early embryonic lethality of H ferritin gene deletion in mice
30. Microcytic anaemia mice have a mutation in Nramp2, a candidate iron transporter gene
31. The immunosuppressive human placental ferritin subunit p43 is produced by activated CD4+ lymphocytes
32. Cockroach transferrin closely resembles vertebrate transferrins in its metal ion-binding properties: A spectroscopic study
33. Drosophila melanogaster ferritin: cDNA encoding a light chain homologue, temporal and tissue specific expression of both subunit types
34. Iron availability dramatically alters the distribution of ferritin subunit messages in Drosophila melanogaster
35. Ferritin. IX. Increase of the protein apoferritin in the gastrointestinal mucosa as a direct response to iron feeding. The function of ferritin in the regulation of iron absorption
36. Iron regulatory protein prevents binding of the 43S translation pre-initiation complex to ferritin and eALAS mRNAs
37. Translational regulation of mammalian and Drosophila citric acid cycle enzymes via iron-responsive elements
38. Cloning and characterization of a mammalian proton-coupled metal-ion transporter
39. Characterization and chromosomal mapping of the human gene for SFT, a stimulator of Fe transport
40. Regulation of genes of iron metabolism by the iron-response proteins
41. Regulation of the iron regulatory proteins by reactive nitrogen and oxygen species
42. Molecular control of vertebrate iron metabolism: mRNA-based regulatory circuits operated by iron, nitric oxide, and oxidative stress
43. A juvenile hormone-repressible transferrin-like protein from the bean bug, Riptortus clavatus: cDNA sequence analysis and protein identification during diapause and vitellogenesis
44. Purification and cDNA cloning of ferritin from the hepatopancreas of the freshwater crayfish Pacifastacus leniusculus
45. An atypical iron-responsive element (IRE) within crayfish ferritin mRNA and an iron regulatory protein 1 (IRP1)-like protein from crayfish hepatopancreas
46. Iron binding proteins and their roles in the tobacco hornworm Manduca sexta (L)
47. Iron-dependent oxidation, ubiquitination, and degradation of iron regulatory protein 2: Implications for degradation of oxidized proteins
48. Transferrin in a cockroach: Molecular cloning, characterization, and suppression by juvenile hormone
49. High levels of ferritin and its iron in fetal bovine serum
50. Molecular cloning of transferrin receptor 2
51. Loops and bulge/loops in iron responsive element isoforms influence iron regulatory protein binding
52. Characterization of an insect ferritin subunit synthesized in a cell-free system
53. Cloning and expression of a ferritin subunit for Galleria mellonella
54. Succinate dehydrogenase b mRNA of Drosophila melanogaster has a functional iron-responsive element in its 5′untranslated region
55. Molecular characterization of an insect transferrin and its selective incorporation into eggs during oogenesis
56. Identification of the ferroxidase centre in ferritin
57. Extremely elevated serum ferritin levels in a university hospital: Associated diseases and clinical significance
58. Structural requirements of iron-responsive elements for binding of the protein involved in both transferrin receptor and ferritin mRNA post-transcriptional regulation
59. Transferrin receptor is necessary for development of erythrocytes and the nervous system
60. A human mitochondrial ferritin encoded by an intronless gene
61. Yeast mitochondrial protein, Nfs1p, coordinately regulates iron-sulfur cluster proteins, cellular iron uptake, and iron distribution
62. CCC1 is a transporter that mediates vacuolar iron storage in yeast
63. Maturation of cellular Fe-S proteins: An essential function of mitochondria
64. Drosophila ferritin mRNA: Alternative RNA splicing regulates the presence of the iron-responsive element
65. Apoferritin in the vacuolar system of insect hemocytes
66. Vacuolar apoferritin synthesis by the fat body of an insect (Calpodes ethlius)
67. The induction and distribution of an insect ferritin - A new function for the endoplasmic reticulum
68. Iron economy in insects
69. Gene structure and polymorphism of an invertebrate nitric oxide synthase gene
70. The mosquito Anopheles stephensi limits malaria parasite development with inducible synthesis of nitric oxide
71. A mono-sited transferrin from a representative deuterostome: The ascidian Pyura stolonifera (subphylum Urochordata)
72. An iron-regulated ferric reductase associated with the absorption of dietary iron
73. A novel duodenal iron-regulated transporter, IREG 1, implicated in the basolateral transfer of iron to the circulation
74. The hairpin loop but not the bulged C of the iron responsive element is essential for high affinity binding to iron regulatory protein-1
75. Translational regulation in vivo of the Drosophila melanogaster mRNA encoding succinate dehydrogenase iron protein via iron responsive elements
76. IRP-1 binding to ferritin mRNA prevents the recruitment of the small ribosomal subunit by the cap-binding complex elF4F
77. Iron-regulatory protein-1 (IRP-1) is highly conserved in two invertebrate species - Characterization of IRP-1 homologues in Drosophila melanogaster and Caenorhabditis elegans
78. The ferritin genes: Their response to iron status
79. Conservation of ferritin heavy subunit gene structure: Implications for the regulation of ferritin gene expression
80. The aconitase function of iron regulatory protein 1. Genetic studies in yeast implicate its role in iron-mediated redox regulation
81. Structural properties of secreted/serum ferritins from the human, rat, and horse
82. Secreted ferritin subunits are of two kinds in insects: Molecular cloning of cDNAs encoding two major subunits of secreted ferritin from Calpodes ethlius
83. The characterization of ferritin in an insect
84. The localization of ferritin in insects
85. The nitric oxide-cGMP pathway may mediate communication between sensory afferents and projection neurons in the antennal lobe of Manduca sexta
86. Metallochaperones, an intracellular shuttle service for metal ions
87. Nitric oxide signaling to iron-regulatory protein: Direct control of ferritin mRNA translation and transferrin receptor mRNA stability in transfected fibroblasts
88. Rapid responses to oxidative stress mediated by iron regulatory protein
89. Activation of iron regulatory protein-1 by oxidative stress in vitro
90. Differences in the regulation of iron regulatory protein-1 (IRP-1) by extra- and intracellular oxidative stress
91. Ribosomal pausing and scanning arrest as mechanisms of translational regulation from cap-distal iron-responsive elements
92. Structure and location of a ferritin gene of the yellow fever mosquito Aedes aegypti
93. Manduca sexta hemolymph ferritin: cDNA sequence and mRNA expression
94. Transcriptional control is relevant in the modulation of mosquito ferritin synthesis by iron
95. Differential regulation of IRP1 and IRP2 by nitric oxide in rat hepatoma cells
96. Organization and function of the inorganic constituents of nuclei
97. The yeast frataxin homologue mediates mitochondrial iron efflux. Evidence for a mitochondrial iron cycle
98. Iron storage in Saccharomyces cerevisiae
99. The visualization of apoferritin in the secretory pathway of vertebrate liver cells
100. The iron loaded cell - The cytopathology of iron storage
101. malvolio, the Drosophila homologue of mouse NRAMP-1 (Bcg), is expressed in macrophages and in the nervous system and is required for normal taste behaviour
102. The mRNA-binding protein which controls ferritin and transferrin receptor expression is conserved during evolution
103. Human serum ferritin G-peptide is recognized by anti-L ferritin subunit antibodies and concanavalin A
104. Translational control of ferritin synthesis by iron in embryonic reticulocytes of the bullfrog
105. The Berkeley Drosophila genome project gene disruption project: Single P-element insertions mutating 25% of vital Drosophila genes
106. The ferritin family of iron storage proteins
107. Differential iron regulation of intracellular and secreted ferritins produced by rat hepatoma cells
108. Three novel families of miniature inverted-repeat transposable elements are associated with genes of the yellow fever mosquito, Aedes aegypti
109. The sequence of the human genome
110. cDNA cloning and deduced amino acid sequence of two ferritins: Soma ferritin and yolk ferritin, from the snail Lymnaea stagnalis L.
111. Nitrogen monoxide activates iron regulatory protein 1 RNA-binding activity by two possible mechanisms: Effect on the [4Fe-4S] cluster and iron mobilization from cells
112. Biochemical properties of canine serum ferritin: Iron content and nonbinding to concanavalin A
113. The development of awareness of iron-withholding defense
114. Pathways for the regulation of macrophage iron metabolism by the anti-inflammatory cytokines II-4 and II-13
115. Translational regulation via iron-responsive elements by the nitric oxide/NO-synthase pathway
116. Immune response and iron metabolism
117. Iron transport
118. Drosophila melanogaster transferrin. Cloning, deduced protein sequence, expression during the life cycle, gene localization and up-regulation on bacterial infection
119. Mosquito transferrin, an acute-phase protein that is up-regulated upon infection
120. Molecular cloning and characterization of a cDNA encoding a transferrin homolog from Bombyx mori
121. Increased levels of microsomal albumin-mRNA in the liver of nephrotic rats
122. Manduca sexta IRP1: Molecular characterization and in vivo response to iron
123. Repression of Manduca sexta ferritin synthesis by IRP1/IRE interaction
124. Cloning and molecular characterization of two mosquito iron regulatory proteins
125. Cloning and structural characterization of porcine heart aconitase