Biosynthesis and secretion of pituitary hormones: Dynamics and regulation

Archives of Physiology and Biochemistry

Volumn 110, Issue 1-2, 2002, Pages 16-25

  Moore, Hsiao Ping H ^a   Andresen, J M ^a   Eaton, B A ^a   Grabe, M ^a   Haugwitz, M ^a   Wu, M M ^a   Machen, T E ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

ADP ribosylation factor 1; Corticotropin secretion; Golgi apparatus; Membrane remodeling; Membrane transport; pH regulation; Post translational protein processing; Prohormone; Secretory granules; Sorting

Indexed keywords

AVIDIN; CALCIUM ION; CELL PROTEIN; CORTICOTROPIN; HYPOPHYSIS HORMONE; PROOPIOMELANOCORTIN; SNARE PROTEIN; SYNAPTOTAGMIN; UNCLASSIFIED DRUG; VAMP4 PROTEIN; CALCIUM BINDING PROTEIN; MEMBRANE PROTEIN; NERVE PROTEIN; SYT4 PROTEIN, HUMAN;

ACIDIFICATION; BIOSYNTHESIS; CELL LINE; CELL MEMBRANE PERMEABILITY; CELL ORGANELLE; CONFERENCE PAPER; ENDOPLASMIC RETICULUM; EXOCYTOSIS; FLUORESCENCE; GOLGI COMPLEX; HORMONAL REGULATION; HORMONE RELEASE; HORMONE SYNTHESIS; HORMONE TRANSPORT; INTRACELLULAR TRANSPORT; MATHEMATICAL MODEL; NONHUMAN; PH MEASUREMENT; PROTEIN PROCESSING; PROTEIN TRANSPORT; SECRETORY GRANULE; ANIMAL; HUMAN; METABOLISM; REVIEW; SECRETION; SECRETORY VESICLE; TRANS GOLGI NETWORK;

ANIMAL; HUMAN; MEMBRANE GLYCOPROTEINS; NERVE TISSUE PROTEINS; PITUITARY HORMONES; SECRETORY VESICLES; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, NON-P.H.S.; SUPPORT, U.S. GOV'T, P.H.S.; TRANS-GOLGI NETWORK; ANIMALS; CALCIUM-BINDING PROTEINS; HUMANS; SYNAPTOTAGMINS;

EID: 0036000162     PISSN: 13813455     EISSN: None     Source Type: Journal    
DOI: 10.1076/apab.110.1.16.903     Document Type: Conference Paper

References (52)

1. Comparison between the natural postnatal maturation and the spermine-induced maturation of the rat intestine
2. Rab1 recruitment of p115 into a cis-SNARE complex: Programming budding COPII vesicles for fusion
3. Biogenesis of processing-competent secretory organelles in vitro
4. Protein sorting and secretion granule formation in regulated secretory cells
5. Sorting and storage during secretory granule biogenesis: Looking forward and looking backward
6. Thyrotropin induces the acidification of the secretory granules of parafollicular cells by increasing the chloride conductance of the granular membrane
7. Defective acidification of intracellular organelles in cystic fibrosis
8. Chronic obstructive pulmonary disease: New opportunities for drug development
9. A role for ADP-ribosylation factor 1, but not COP I, in secretory vesicle biogenesis from the trans-Golgi network
10. Constitutive and regulated secretion
11. +-ATPase in living cells
12. A biosynthetic regulated pathway in constitutive secretory cells
13. Phospholipase D stimulates release of nascent secretory vesicles from the trans-Golgi network
14. Mechanism of acidification of the trans-Golgi network (TGN)
15. Biogenesis of regulated exocytotic carriers in neuroendocrine cells
16. Deficits in memory and motor performance in synaptotagmin IV mutant mice
17. Distinct molecular events during secretory granule biogenesis revealed by sensitivities to brefeldin A
18. +-ATPase in regulating ATP-dependent endosome acidification
19. Regulation of organelle acidity
20. Two distinct intracellular pathways transport secretory and membrane glycoproteins to the surface of pituitary tumor cells
21. Out of the ER-out-fitters, escorts and guides
22. The internal pH and membrane potential of the insulin-secretory granule
23. Membrane fusion and exocytosis
24. Growth cone and dendrite dynamics in zebrafish embryos: Early events in synaptogenesis imaged in vivo
25. Effects of activated ADP-ribosylation factors on Golgi morphology require neither activation of phospholipase D1 nor recruitment of coatomer
26. COPII-cargo interactions direct protein sorting into ER-derived transport
27. Protein targeting via the 'constitutive-like' secretory pathway in isolated pancreatic islets: Passive sorting in the immature granule compartment
28. Synaptic function modulated by changes in the ratio of synaptotagmin I and IV
29. p200 ARF-GEP1: A Golgi-localized guanine nucleotide exchange protein whose Sec7 domain is targeted by the drug brefeldin A
30. Reduced temperature prevents transfer of a membrane glycoprotein to the cell surface but does not prevent terminal glycosylation
31. A subclass of proteins and sulfated macromolecules secreted by AtT-20 (mouse pituitary tumor) cells is sorted with adrenocorticotropin into dense secretory granules
32. Expressing a human proinsulin cDNA in a mouse ACTH secretory cell. Intracellular storage, proteolytic processing and secretion on stimulation
33. Brefeldin A inhibited activity of the sec7 domain of p200, a mammalian guanine nucleotide-exchange protein for ADP-ribosylation factors
34. Three-dimensional electron microscopy: Structure of the Golgi apparatus
35. Formation of secretion granules in the Golgi apparatus of pancreatic acinar cells of the rat
36. Tridimensional architecture of the Golgi apparatus and its components in mucous cells of Brunner's glands of the mouse
37. Autocrine loops, signal transduction, and cell cycle abnormalities in the molecular biology of lung cancer
38. Determinants of the pH of the Golgi complex
39. Synthesis and targeting of insulin-like growth factor-I to the hormone storage granules in an endocrine cell line
40. Ionic milieu controls the compartment-specific activation of pro-opiomelanocortin processing in AtT-20 cells
41. Proteolytic processing of pro-ACTH endorphin begins in the Golgi complex of pituitary corticotropes and AtT-20 cells
42. Targeting and activation of peptide hormones in the secretory pathway
43. Protein and lipid sorting from the trans-Golgi network to secretory granules-recent developments
44. Functional and biochemical analysis of the C2 domains of synaptotagmin IV
45. Secretory granule biogenesis: Rafting to the SNARE
46. Protein traffic from the secretory pathway to the endosomal system in pancreatic beta-cells
47. 2+ binding
48. Homotypic fusion of immature secretory granules during maturation requires syntaxin 6
49. Mechanisms of pH regulation in the regulated secretory pathway
50. Organelle pH studies using targeted avidin and fiuorescein-biotin
51. Studying organelle physiology using targeted avidin and fluorescein-biotin
52. The prohormone convertases PC1 and PC2 mediate distinct endoproteolytic cleavages in a strict temporal order during proopiomelanocortin biosynthetic processing