Pathogenesis of refractory secondary hyperparathyroidism

Kidney International, Supplement

Volumn 61, Issue 80, 2002, Pages

  Rodriguez, Mariano ^a   Canalejo, Antonio ^a   Garfia, Bartolome ^a   Aguilera, Escolastico ^a   Almaden, Yolanda ^a  

^a HOSPITAL UNIVERSITARIO REINA SOFÍA   (Spain)

Author keywords

Calcitrol; Nodular hyperplasia; Parathyroid homone; Uremia; Vitamin D receptor

Indexed keywords

CALCITRIOL; CALCIUM SENSING RECEPTOR; PARATHYROID HORMONE; TRANSFORMING GROWTH FACTOR ALPHA; VITAMIN D RECEPTOR;

CALCIUM BLOOD LEVEL; CELL PROLIFERATION; CONFERENCE PAPER; HEMODIALYSIS; HORMONE SYNTHESIS; HUMAN; HYPERPHOSPHATEMIA; HYPOCALCEMIA; KIDNEY FAILURE; NODULAR HYPERPLASIA; NONHUMAN; PARATHYROID HORMONE RELEASE; PARATHYROIDECTOMY; PATHOGENESIS; PHOSPHATE BLOOD LEVEL; PRIORITY JOURNAL; PROTEIN EXPRESSION; RECEPTOR DENSITY; SECONDARY HYPERPARATHYROIDISM; UREMIA; HYPERPLASIA; PARATHYROID GLAND; PATHOLOGY; PATHOPHYSIOLOGY; REVIEW;

HUMANS; HYPERPARATHYROIDISM, SECONDARY; HYPERPLASIA; PARATHYROID GLANDS;

EID: 0035999940     PISSN: 00986577     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1523-1755.61.s80.26.x     Document Type: Conference Paper

References (56)

1. Marked suppression of secondary hyperparathyroidism by intravenous administration of 1,25-dihydroxy-cholecalciferol in uremic patients
2. Prospective trial of pulse oral versus intravenous calcitriol treatment of hyperparathroidism in ESRD
3. Low-dose intravenous calcitriol treatment of secondary hyperparathyroidism in hemodialysis patients
4. Reduction of functioning parathyroid cell mass by ethanol injection in chronic dialysis patients
5. Secondary hyperparathyroidism in chronic haemodialysis patients: A clinico-pathological study
6. Short and long-term efficacy of total parathyroidectomy with immediate autografting compared with subtotal parathyroidectomy in hemodialysis patients
7. 3 receptor density is associated with a more severe form of parathyroid hyperplasia in chronic uremic patients
8. +-sensing receptor in primary and uremic secondary hyperparathyroidism
9. Depressed expression of calcium receptor in parathyroid gland tissue of patients with primary or secondary uremic hyperparathyroidism
10. The effect of longterm intravenous calcitriol administration on parathyroid function in hemodialysis patients
11. Treatment of hyperparathyroidism - Why is it crucial to control serum phosphate?
12. Parathyroid function as a determinant of the response to calcitriol treatment in the hemodialysis patient
13. Relationship between the concentration and rate of change of calcium and serum intact parathyroid hormone levels in normal humans
14. Evidence for both abnormal set point of calcium and adaptation to serum calcium in hemodialysis patients with secondary hyperparathyroidism
15. The pathogenesis of parathyroid gland hyperplasia in chronic renal failure
16. The hyperparathyroidism of chronic renal failure: A disorder of growth
17. Relationship between external and cytoplasmic calcium concentrations, parathyroid hormone release and weight of parathyroid glands in human hyperparathyroidism
18. High phosphorus directly stimulates parathyroid hormone secretion and synthesis by human parathyroid tissue in vitro
19. The in vitro effect of calcitriol on parathyroid cell proliferation and apoptosis
20. DNA repair and recovery of RNA synthesis in uremic patients
21. Histopathology, pathophysiology, and indications for surgical treatment of renal hyperparathyroidism
22. Parathyroidectomy in chronic renal failure
23. Nodular foci in parathyroid adenomas and hyperplasias: An immunohistochemical analysis of proliferative activity
24. DNA ploidy pattern of parathyroid parenchymal cells in renal secondary hyperparathyroidism with relapse
25. Expression of proliferating cell nuclear antigens in parathyroid glands of renal hyperparathyroidism
26. Recurrent renal hyperparathyroidism and DNA analysis of autografted parathyroid tissue
27. Monoclonality of parathyroid tumors in chronic renal failure and in primary parathyroid hyperplasia
28. Clonal analysis of nodular parathyroid hyperplasia in renal hyperparathyroidism
29. Genetic abnormalities in parathyroid nodules of uremic patients
30. Differential loss of heterozygosity in familial, sporadic, and uremic hyperparathyroidism
31. Progression of uremic hyperparathyroidism involves allelic loss on chromosome 11
32. Novel clonal chromosomal defects identified by comparative genomic hybridization and molecular allotyping in refractory hyperparathyroidism of uremia
33. Structural analysis of gene marker loci on chromosomes 10 and 11 in primary and secondary uraemic hyperparathyroidism
34. Parathyroid cell proliferation in normal and chronic renal failure rats. The effects of calcium, phosphate, and vitamin D
35. The calcimimetic compound NPS R-568 suppresses parathyroid cell proliferation in rats with renal insufficiency. Control of parathyroid cell growth via a calcium receptor
36. 3 inhibits parathyroid cell proliferation in experimental uremia
37. Influence of calcium and 1,25-dihydroxycholecalciferol on proliferation and proto-oncogene expression in primary cultures of bovine parathyroid cells
38. Regulation of parathyroid hormone synthesis in chronic renal failure in rats
39. Association between vitamin D receptor gene polymorphism and relative hypoparathyroidism in patients with chronic renal failure
40. 3 receptors in peripheral blood mononuclear cells from patients with renal insufficiency
41. The BsmI vitamin D-recptor polymorphism and secondary hyperparathyroidism
42. Influence of vitamin D receptor genotype on bone mass changes after renal transplantation
43. Vitamin D receptor alleles b, a, and T: Risk factors for sporadic primary hyperparathyroidism (HPT) but not HPT of uremia of MEN 1
44. Direct effect of phosphorus on parathyroid hormone secretion from whole rat parathyroid glands in vitro
45. High phosphorus diet increases preproPTH mRNA independent of calcium and calcitriol in normal rats
46. Effect of serum phosphate on parathyroid hormone secretion during hemodialysis
47. Effect of phosphate on PTH secretion in vivo
48. Prevention of enhanced parathyroid hormone secretion, synthesis and hyperplasia by mild dietary phosphorus restriction in early chronic renal failure in rats: Possible direct role of phosphorus
49. Phosphorus restriction prevents parathyroid gland growth: High phosphorus directly stimulates PTH secretion in vitro
50. The effect of high phosphorus diet on the parathyroid cell cycle
51. Decreased calcium-sensing receptor expression in hyperplastic parathyroid glands of uremic rats: Role of dietary phosphate
52. Parathyroid hyperplasia in uremic rats precedes down-regulation of the calcium receptor
53. (WAF1) and transforming growth factor-α mediate dietary phosphate regulation of parathyroid cell growth
54. Acidic fibroblast growth factor autocrine system as a mediator of calcium-regulated parathyroid cell growth
55. Proliferation of parathyroid cells negatively correlates with expression of parathyroid hormone-related protein in secondary parathyroid hyperplasia
56. De novo expression of transforming growth factor-a in parathyroid gland tissue of patients with primary or secondary uraemic hyperparathyroidism