In vitro inhibition of cytidine triphosphate synthetase activity by cyclopentenyl cytosine in paediatric acute lymphocytic leukaemia

British Journal of Haematology

Volumn 110, Issue 1, 2000, Pages 161-169

  Verschuur, Arnauld C ^a   Van Gennip, Albert H ^a   Leen, Rene ^a   Meinsma, Rutger ^a   Voute, P A ^a   Van Kuilenburg, André B P ^a  

^a UNIVERSITY OF AMSTERDAM   (Netherlands)

Author keywords

ALL; CTP synthetase; Cyclopentenyl; Cytosine; Ribonucleotides

Indexed keywords

1 (4,5 DIHYDROXY 3 HYDROXYMETHYL 2 CYCLOPENTEN 1 YL)CYTOSINE; CYTIDINE TRIPHOSPHATE; MESSENGER RNA; RIBONUCLEOTIDE; SYNTHETASE; URIDINE;

ACUTE LYMPHOCYTIC LEUKEMIA; ARTICLE; CHILD; CONTROLLED STUDY; CYTOSTASIS; DOSE RESPONSE; ENZYME ACTIVITY; ENZYME INHIBITION; HUMAN; HUMAN CELL; ISOTOPE LABELING; LEUKEMIA CELL; LEUKOCYTE COUNT; LYMPHOBLAST; LYMPHOCYTE; MAJOR CLINICAL STUDY; PRIORITY JOURNAL; PYRIMIDINE SYNTHESIS;

ADULT; ANTIGENS, CD34; CARBON-NITROGEN LIGASES; CASE-CONTROL STUDIES; CELLS, CULTURED; CHILD; CHILD, PRESCHOOL; CYTIDINE; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME INHIBITORS; FEMALE; HEMATOPOIETIC STEM CELLS; HUMANS; LEUKEMIA, LYMPHOCYTIC, ACUTE, L1; LYMPHOCYTES; MALE; RIBONUCLEOTIDES; RNA, MESSENGER; STATISTICS, NONPARAMETRIC;

EID: 0033871566     PISSN: 00071048     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2141.2000.02136.x     Document Type: Article

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