메뉴 건너뛰기




Volumn 39, Issue 3, 2002, Pages 187-196

Direct thrombin inhibitors

Author keywords

[No Author keywords available]

Indexed keywords

ARGATROBAN; HEPARIN; HEPARIN DERIVATIVE; HIRULOG; LEPIRUDIN; MELAGATRAN; SERINE PROTEINASE; THROMBIN; THROMBIN INHIBITOR; XIMELAGATRAN; ANTICOAGULANT AGENT;

EID: 0035992747     PISSN: 00371963     EISSN: None     Source Type: Journal    
DOI: 10.1053/shem.2002.34092     Document Type: Article
Times cited : (63)

References (81)
  • 2
    • 0028092111 scopus 로고
    • Hirudin in acute myocardial infarction: Safety report from the thrombolysis and Thrombin Inhibition in Myocardial Infarction (TIMI) 9A Trial
    • (1994) Circulation , vol.90 , pp. 1624-1630
    • Antman, E.1
  • 6
    • 0000466747 scopus 로고    scopus 로고
    • Efficacy and safety of subcutaneous melagatran and oral ximelagatran (pINN, formerly H376/95) as prophylaxis against thromboembolic complications following general abdominal surgery
    • abstr
    • (2001) Thromb Haemost , vol.86 , pp. 1020
    • Bergqvist, D.1    Holmdahl, L.2    Solhaug, J.-H.3
  • 15
    • 0003355483 scopus 로고    scopus 로고
    • Randomized, double-blind, comparison of ximelagatran, an oral direct thrombin inhibitor, and enoxaparin to prevent venous thromboembolism after total hip arthroplasty
    • abstr
    • (2001) Blood , vol.98 , Issue.SUPPL. 1
    • Colwell, C.1    Berkowitz, S.2    Davidson, B.3
  • 17
    • 0014191175 scopus 로고
    • Actions of thrombin and other coagulant and proteolytic enzymes on blood platelets
    • (1967) Nature , vol.216 , pp. 857-858
    • Davey, M.1    Luscher, E.2
  • 18
    • 0035251820 scopus 로고    scopus 로고
    • Effect of activated prothrombin complex concentrate or recombinant factor VIIa on the bleeding time and thrombus formation during anticoagulation with a direct thrombin inhibitor
    • (2001) Thromb Res , vol.101 , pp. 145-157
    • Elg, M.1    Carlsson, S.2    Gustafsson, D.3
  • 21
    • 0000735336 scopus 로고    scopus 로고
    • Effect of melagatran, the active form of the oral direct thrombin inhibitor, ximelagatran (p1NN, formerly H376/95), on activated partial thromboplastin time in orthopaedic surgery patients treated to prevent deep vein thrombosis and pulmonary embolism
    • abstr
    • (2001) Thromb Haemost , vol.86 , pp. 3093
    • Eriksson, U.1    Frison, L.2    Gustafsson, D.3
  • 22
    • 0000735336 scopus 로고    scopus 로고
    • The pharmacokinetics of melagatran, the active form of the oral direct thrombin inhibitor, ximelagatran (pINN, formerly H376/95), in orthopaedic surgery patients treated to prevent deep venous thrombosis and pulmonary embolism
    • abstr
    • (2001) Thromb Haemost , vol.86 , pp. 3092
    • Eriksson, U.1    Frison, L.2    Gustafsson, D.3
  • 23
    • 79960971646 scopus 로고    scopus 로고
    • The pharmacokinetics and pharmacodynamics of oral ximelagatran and subcutaneous melagatran in patients with severe renal impairment
    • abstr
    • (2001) Blood , vol.98 , Issue.SUPPL. 1
    • Eriksson, U.1    Samuelsson, O.2    Attman, P.-O.3
  • 24
    • 0024558370 scopus 로고
    • The roles of protein C and thrombomodulin in the regulation of blood coagulation
    • (1989) J Biol Chem , vol.264 , pp. 4743-4746
    • Esmon, C.1
  • 27
    • 0005844253 scopus 로고    scopus 로고
    • Bleeding effects of antithrombin drugs can be neutralized by activated FVIIa (NovoSeven) and combinations of other plasma-derived products
    • abstr
    • (2001) Thromb Haemost , vol.86 , pp. 2614
    • Fareed, J.1    Walenga, J.2    Bender, N.3
  • 28
    • 0005844254 scopus 로고    scopus 로고
    • Randomized, double-blind comparative study of ximelagatran (pINN, formerly H 376/95), an oral direct thrombin inhibitor, and warfarin to prevent venous thromboembolism (VTE) after total knee arthroplasty
    • abstr
    • (2001) Thromb Haemost , vol.86 , pp. 44
    • Francis, C.1    Davidson, B.2    Berkowitz, S.3
  • 33
  • 36
    • 0035829034 scopus 로고    scopus 로고
    • Comparison of the oral direct thrombin inhibitor ximelagatran with enoxaparin as prophylaxis against venous thromboembolism after total knee replacement
    • (2001) Arch Intern Med , vol.161 , pp. 2215-2221
    • Heit, J.1    Colwell, C.2    Francis, C.3
  • 39
    • 0025981535 scopus 로고
    • The influence of infusions of 1-desamino-8-D-arginine vasopressin (DDAVP) in vivo on the anticoagulant effect of recombinant hirudin (CGP39393) in vitro
    • (1991) Thromb Haemost , vol.65 , pp. 64-66
    • Ibbotson, I.1    Grant, P.2    Kerry, R.3
  • 40
    • 79960970655 scopus 로고    scopus 로고
    • Dosage adjustment of argatroban justified in combination with glycoprotein IIb/IIIa receptor antagonist: Laboratory and clinical implications
    • abstr
    • (2001) Blood , vol.98 , Issue.SUPPL. 1
    • Iqbal, O.1    Lewis, B.2    Ahmad, D.3
  • 44
    • 0028243705 scopus 로고
    • Immunoglobulin G from patients with heparin-induced thrombocytopenia binds to a complex of heparin and platelet factor 4
    • (1994) Blood , vol.83 , pp. 3232-3239
    • Kelton, J.1    Smith, J.2    Warkentin, T.3
  • 47
    • 4244106685 scopus 로고    scopus 로고
    • Argatroban use in patients with heparin-induced thrombocytopenia during percutaneous coronary intervention
    • abstr
    • (2000) Chest , vol.11 , Issue.SUPPL. , pp. 216
    • Lewis, B.1    Cohen, M.2    Leya, F.3
  • 48
    • 0003237268 scopus 로고    scopus 로고
    • Argatroban anticoagulation during initial and repeat percutaneous coronary intervention (PCI) in patients with heparin-induced thrombocytopenia
    • abstr
    • (2000) Am J Cardiol , vol.86 , Issue.SUPPL. 8A
    • Lewis, B.1    Cohen, M.2    Moses, J.3
  • 49
    • 0000078830 scopus 로고    scopus 로고
    • Results of phase 2/3 trial of argatroban anticoagulation during PTCA of patients with heparin-induced thrombocytopenia (HIT)
    • abstr
    • (1997) Circulation , vol.96 , Issue.SUPPL. , pp. 217
    • Lewis, B.1    Matthai, W.2    Grassman, E.D.3
  • 53
    • 0027442550 scopus 로고
    • Heparin-induced thrombocytopenia (HIT): An overview of 230 patients treated with Orgaran (Org 10172)
    • (1993) Thromb Haemost , vol.70 , pp. 554-561
    • Magnani, H.1
  • 57
    • 79960970693 scopus 로고    scopus 로고
    • Argatroban use in patients with a history of heparin-induced thrombocytopenia who require acute anticoagulation
    • abstr
    • (2001) Blood , vol.98 , Issue.SUPPL. 1
    • Matthai, W.J.1    Hursting, M.2    Lewis, B.3
  • 60
    • 7144253804 scopus 로고    scopus 로고
    • Randomized comparison of direct thrombin inhibition versus heparin in conjunction with fibrinolytic therapy for acute myocardial infarction
    • (1998) J Am Coll Cardiol , vol.31 , pp. 1493-1498
    • Metz, B.1    White, H.2    Granger, C.3
  • 61
    • 0028117846 scopus 로고
    • Safety observations from the pilot phase of the randomized r-Hirudin for improvement of thrombolysis (HIT-III) study: A study of the Arbeitsgemeinschaft Leitender Kardolischer Krankenhausartze (ALKK)
    • (1994) Circulation , vol.90 , pp. 1638-1642
    • Neuhaus, K.-L.1    Von Essen, R.2    Tebbe, U.3
  • 62
    • 0343580449 scopus 로고    scopus 로고
    • Comparison of the effects of two doses of recombinant hirudin compared with heparin in patients with acute myocardial ischemia without ST elevation: A pilot study
    • (1997) Circulation , vol.96 , pp. 769-777
  • 63
    • 0033528281 scopus 로고    scopus 로고
    • Effects of recombinant hirudin (lepirudin) compared with heparin on death, myocardial infarction, refractory angina, and revascularization procedures in patients with myocardial infarction without ST elevation: A randomized trial
    • (1999) Lancet , vol.353 , pp. 429-438
  • 65
    • 0003326416 scopus 로고    scopus 로고
    • A long-term follow-up of ximelagatran as an oral anticoagulant for the prevention of stroke and systemic embolism in patients with atrial fibrillation
    • abstr
    • (2001) Blood , vol.98 , Issue.SUPPL. 1
    • Petersen, P.1
  • 67
    • 79960970777 scopus 로고    scopus 로고
    • Lack of effect of obesity on the pharmacokinetics and pharmacodynamics of melagatran after oral administration of ximelagatran
    • abstr
    • (2001) Blood , vol.98 , Issue.SUPPL. 1
    • Sarich, T.1    Teng, R.2    Peters, G.3
  • 68
    • 0002981196 scopus 로고    scopus 로고
    • THRIVE 1: Efficacy and tolerability of the novel, oral direct thrombin inhibitor ximelagatran compared with standard therapy for the treatment of acute deep vein thrombosis
    • abstr
    • (2001) Blood , vol.98 , Issue.SUPPL. 1
    • Schulman, S.1    Wahlander, K.2    Gustafsson, D.3
  • 69
    • 0033527370 scopus 로고    scopus 로고
    • Generation of anti-hirudin antibodies in heparin-induced thrombocytopenic patients treated with r-hirudin
    • (1999) Circulation , vol.100 , pp. 1528-1532
    • Song, X.1    Huhle, G.2    Wang, L.3
  • 72
    • 0034049121 scopus 로고    scopus 로고
    • The pharmacokinetics and pharmacodynamics of argatroban: Effects of age, gender, and hepatic or renal dysfunction
    • (2000) Pharmacotherapy , vol.20 , pp. 318-329
    • Swan, S.1    Hursting, M.2
  • 73
    • 0029835392 scopus 로고    scopus 로고
    • A comparison of recombinant hirudin with heparin for the treatment of acute coronary syndromes
    • (1996) N Engl J Med , vol.335 , pp. 775-782
  • 74
    • 0028037517 scopus 로고
    • Randomized trial of intravenous heparin versus recombinant hirudin for acute coronary syndrome
    • (1994) Circulation , vol.90 , pp. 1631-1637
  • 79
    • 0025146426 scopus 로고
    • Clot-bound thrombin is protected from inhibition by heparin-antithrombin III but is susceptible to inactivation by antithrombin III-independent inhibitors
    • (1990) J Clin Invest , vol.86 , pp. 385-391
    • Weitz, J.1    Hudoba, M.2    Massel, D.3
  • 80
    • 0030771823 scopus 로고    scopus 로고
    • Randomized, double-blind comparison of hirulog versus heparin in patients receiving streptokinase and aspirin for acute myocardial infarction (HERO)
    • (1997) Circulation , vol.96 , pp. 2155-2161
    • White, H.1    Aylward, P.2    Frey, M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.