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Volumn 91, Issue 8, 2002, Pages 1817-1826
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The influence of lipids on stereoselective pharmacokinetics of halofantrine: Important implications in food-effect studies involving drugs that bind to lipoproteins
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Author keywords
Halofantrine; Hyperlipidemia; Lipids; Lipoproteins; Stereoselectivity
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Indexed keywords
ANTIMALARIAL AGENT;
ARACHIS OIL;
CHOLESTEROL;
HALOFANTRINE;
LIPID;
LIPOPROTEIN;
PHENANTHRENE DERIVATIVE;
PLASMA PROTEIN;
POLOXAMER;
TRIACYLGLYCEROL;
VEGETABLE OIL;
ANIMAL;
AREA UNDER THE CURVE;
ARTICLE;
BIOAVAILABILITY;
BLOOD;
CHEMISTRY;
COMPARATIVE STUDY;
FAT INTAKE;
FOOD DRUG INTERACTION;
HIGH PERFORMANCE LIQUID CHROMATOGRAPHY;
HYPERLIPIDEMIA;
INTRAVENOUS DRUG ADMINISTRATION;
LIPID METABOLISM;
MALE;
METABOLISM;
ORAL DRUG ADMINISTRATION;
PROTEIN BINDING;
RAT;
SPRAGUE DAWLEY RAT;
STEREOISOMERISM;
ANIMAL EXPERIMENT;
ANIMAL MODEL;
ANIMAL TISSUE;
CONTROLLED STUDY;
DRUG BIOAVAILABILITY;
DRUG BLOOD LEVEL;
DRUG CLEARANCE;
DRUG DISTRIBUTION;
DRUG PROTEIN BINDING;
NONHUMAN;
STEREOCHEMISTRY;
ADMINISTRATION, ORAL;
ANIMALS;
ANTIMALARIALS;
AREA UNDER CURVE;
BIOLOGICAL AVAILABILITY;
BLOOD PROTEINS;
CHOLESTEROL;
CHROMATOGRAPHY, HIGH PRESSURE LIQUID;
DIETARY FATS;
FOOD-DRUG INTERACTIONS;
HYPERLIPIDEMIAS;
INJECTIONS, INTRAVENOUS;
LIPID METABOLISM;
LIPIDS;
LIPOPROTEINS;
MALE;
PHENANTHRENES;
PLANT OILS;
POLOXAMER;
PROTEIN BINDING;
RATS;
RATS, SPRAGUE-DAWLEY;
STEREOISOMERISM;
TRIGLYCERIDES;
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EID: 0035991638
PISSN: 00223549
EISSN: None
Source Type: Journal
DOI: 10.1002/jps.10182 Document Type: Article |
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Times cited : (43)
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References (26)
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