Overexpression of parathyroid hormone-related protein causes hypercalcemia but not bone metastases in a murine model of mammary tumorigenesis

Journal of Bone and Mineral Research

Volumn 17, Issue 7, 2002, Pages 1164-1170

  Wysolmerski, John J ^a   Dann, Pamela R ^a   Zelazny, Edward ^a   Dunbar, Maureen E ^b   Insogna, Karl L ^a   Guise, Theresa A ^c   Perkins, Archibald S ^a,d  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b PENNSYLVANIA STATE UNIVERSITY   (United States)

^c UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO   (United States)

^d YALE UNIVERSITY   (United States)

Author keywords

Bone metastases; Breast cancer; Chemical carcinogen; Parathyroid hormone related protein; Transgenic mice

Indexed keywords

DIMETHYLBENZ[A]ANTHRACENE; PARATHYROID HORMONE RELATED PROTEIN; PEPTIDE HORMONE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BONE METASTASIS; BREAST CARCINOGENESIS; BREAST CARCINOMA; CANCER CELL CULTURE; CONTROLLED STUDY; FEMALE; GENE OVEREXPRESSION; HORMONE ACTION; HYPERCALCEMIA; METASTASIS; MOUSE; MOUSE STRAIN; NONHUMAN; OSTEOLYSIS; PROTEIN BLOOD LEVEL; STRAIN DIFFERENCE; TRANSGENE; TRANSGENIC MOUSE; WILD TYPE; ANIMAL; BLOOD; BONE TUMOR; CELL CULTURE; DISEASE MODEL; EXPERIMENTAL NEOPLASM; GENE EXPRESSION; GENETICS; MALE; PATHOPHYSIOLOGY;

ANIMAL; BONE NEOPLASMS; DISEASE MODELS, ANIMAL; FEMALE; GENE EXPRESSION; HYPERCALCEMIA; MALE; MAMMARY NEOPLASMS, EXPERIMENTAL; MICE; MICE, TRANSGENIC; NEOPLASM METASTASIS; PEPTIDE HORMONES; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, NON-P.H.S.; SUPPORT, U.S. GOV'T, P.H.S.; TUMOR CELLS, CULTURED; ANIMALS; PARATHYROID HORMONE-RELATED PROTEIN;

EID: 0035991229     PISSN: 08840431     EISSN: None     Source Type: Journal    
DOI: 10.1359/jbmr.2002.17.7.1164     Document Type: Article

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