Expression of Nedd5, a mammalian septin, in human brain tumors

Journal of Neuro-Oncology

Volumn 57, Issue 3, 2002, Pages 169-177

  Sakai, Keiichi ^a   Kurimoto, Masanori ^a   Tsugu, Atsushi ^a   Hubbard, Sherri L ^a   Trimble, William S ^a   Rutka, James T ^b  

^a Arthur and Sonia Labatt Brain Tumour Research Centre   (Canada)

^b HOSPITAL FOR SICK CHILDREN   (Canada)

Author keywords

Astrocytoma; Cell division; Cytokinesis; Mitosis; Nedd5; Septins

Indexed keywords

CYTOSKELETON PROTEIN; GUANOSINE TRIPHOSPHATASE; COMPLEMENTARY DNA; F ACTIN; MEVINOLIN; NEDD5 PROTEIN; NOCODAZOLE; SEPTIN; UNCLASSIFIED DRUG;

ARTICLE; ASTROCYTOMA; BRAIN TUMOR; CELL CULTURE; CELL CYCLE G2 PHASE; CELL CYCLE S PHASE; CELL DIVISION; CHEMISTRY; CYTOLOGY; FLOW CYTOMETRY; GENE EXPRESSION REGULATION; GENETICS; HUMAN; MITOSIS; NEUROECTODERM TUMOR; NUCLEIC ACID PROBE; PHYSIOLOGY; ACTIN FILAMENT; ASTROCYTOMA CELL; BIOACCUMULATION; CELL CYCLE; CELL CYCLE G1 PHASE; CELL GROWTH; CELL NUCLEUS; CELL POPULATION; CELL STRUCTURE; CELL SYNCHRONIZATION; CELLULAR DISTRIBUTION; CLONE; CONTROLLED STUDY; CYTOKINESIS; DNA VECTOR; GENETIC TRANSFECTION; HUMAN CELL; IMMUNOCYTOCHEMISTRY; INHIBITION KINETICS; NORTHERN BLOTTING; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; STAINING; TUMOR CELL CULTURE; TUMOR CELL LINE; WESTERN BLOTTING;

ANTISENSE ELEMENTS (GENETICS); ASTROCYTOMA; BRAIN NEOPLASMS; CELL DIVISION; CYTOSKELETAL PROTEINS; FLOW CYTOMETRY; G2 PHASE; GENE EXPRESSION REGULATION, NEOPLASTIC; GTP PHOSPHOHYDROLASES; HUMANS; MITOSIS; NEUROECTODERMAL TUMORS, PRIMITIVE; S PHASE; TUMOR CELLS, CULTURED; HUMAN; SUPPORT, NON-U.S. GOV'T;

EID: 0035990083     PISSN: 0167594X     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1015721801075     Document Type: Article

References (35)

1. Cytokinesis: An emerging unified theory for eukaryotes?
2. Immunofluorescence localization of the Saccharomyces cerevisiae CDC12 gene product to the vicinity of the 10-nm filaments in the mother-bud neck
3. The septins: Roles in cytokinesis and other processes
4. Septin scaffolds and cleavage planes in Saccharomyces
5. Compartmentalization of the cell cortex by septins is required for maintenance of cell polarity in yeast
6. Plasma membrane compartmentalization in yeast by messenger RNA transport and a septin diffusion barrier
7. Septins: Cytoskeletal polymers or signalling GTPases?
8. The Drosophila peanut gene is required for cytokinesis and encodes a protein similar to yeast putative bud neck filament proteins
9. Nedd5, a mammalian septin, is a novel cytoskeletal component interacting with actin-based structures
10. Identification of a developmentally regulated septin and involvement of the septins in spore formation in Saccharomyces cerevisiae
11. Localization and possible functions of Drosophila septins
12. Subunit composition, protein interactions, and structures of the mammalian brain sec6/8 complex and septin filaments
13. The septin CDCrel-1 binds syntaxin and inhibits exocytosis
14. MSF (MLL septin-like fusion), a fusion partner gene of MLL, in a therapy-related acute myeloid leukemia with a t(11; 17)(q23; q25)
15. Genomic and expression analyses of alternatively spliced transcripts of the MLL septin-like fusion gene (MSF) that map to a 17q25 region of loss in breast and ovarian tumors
16. A human gene similar to Drosophila melanogaster peanut maps to the DiGeorge syndrome region of 22q11
17. Identification of septins in neurofibrillary tangles in Alzheimer's disease
18. A novel mitochondrial septin-like protein, ARTS, mediates apoptosis dependent on its P-loop motif
19. Establishment and characterization of a cell line from a human gliosarcoma
20. Establishment and characterization of five cell lines derived from human malignant gliomas
21. Cyclins and cyclin-dependent kinase expression in human astrocytoma cell lines
22. Characterization of the mammalian septin H5: Distinct patterns of cytoskeletal and membrane association from other septin proteins
23. A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity
24. Tight control of gene expression in mammalian cells by tetracycline-responsive promoters
25. Identification of a set of genes with developmentally down-regulated expression in the mouse brain
26. Phosphorylation of a new brain-specific septin, G-septin, by cGMP-dependent protein kinase
27. Septin-dependent assembly of a cell cycle-regulatory module in Saccharomyces cerevisiae
28. Genetic control of the cell division cycle in yeast. IV. Genes controlling bud emergence and cytokinesis
29. Loss of filamentous ring in cytokinesis-defective mutants of budding yeast
30. A purified Drosophila septin complex forms filaments and exhibits GTPase activity
31. Cellular morphogenesis in the Saccharomyces cerevisiae cell cycle: Localization of the CDC3 gene product and the timing of events at the budding site
32. A new 82-kD barbed end-capping protein (radixin) localized in the cell-to-cell adherens junction: Purification and characterization
33. Isolation and mapping of a human septin gene to a region on chromosome 17q, commonly deleted in sporadic epithelial ovarian tumors
34. The septins are required for the mitosis-specific activation of the Gin4 kinase
35. Molecular cytogenetic analysis of medulloblastomas and supratentorial primitive neuroectodermal tumors by using conventional banding, comparative genomic hybridization, and spectral karyotyping