Otitis media

Expert Opinion on Pharmacotherapy

Volumn 3, Issue 8, 2002, Pages 1073-1090

  Pichichero, Michael E ^a   Casey, Janet R ^a  

^a UNIVERSITY OF ROCHESTER MEDICAL CENTER   (United States)

Author keywords

Aminopenicillins; Antibiotics; Cephalosporins; Fluoroquinolones; Macrolides; Otitis media

Indexed keywords

AMINOPENICILLIN; AMOXICILLIN; AMOXICILLIN PLUS CLAVULANIC ACID; AMPICILLIN; ANALGESIC AGENT; ANTIHISTAMINIC AGENT; ANTIINFECTIVE AGENT; ANTIINFLAMMATORY AGENT; AZITHROMYCIN; CEFACLOR; CEFADROXIL; CEFALEXIN; CEFPROZIL; CEFUROXIME AXETIL; CEPHALOSPORIN DERIVATIVE; CLINDAMYCIN; COTRIMOXAZOLE; DECONGESTIVE AGENT; KETOLIDE; LORACARBEF; MACROLIDE; PEDIAZOLE; PENICILLIN G; PENICILLIN V; PLACEBO; STEROID; SULFAFURAZOLE; SULFONAMIDE; TETRACYCLINE DERIVATIVE; UNINDEXED DRUG; ZITHTROMAX;

ADOLESCENT; ANTIBIOTIC PROPHYLAXIS; ANTIBIOTIC RESISTANCE; ANTIBIOTIC SENSITIVITY; ANTIMICROBIAL ACTIVITY; CHILD; CONTROLLED STUDY; DIARRHEA; DRUG ABSORPTION; DRUG EFFICACY; DRUG HALF LIFE; DRUG HYPERSENSITIVITY; DRUG MEGADOSE; DRUG PROTEIN BINDING; ERYTHEMA MULTIFORME; FOOD DRUG INTERACTION; HAEMOPHILUS INFLUENZAE; HUMAN; MORAXELLA CATARRHALIS; MYRINGOTOMY; OTITIS MEDIA; REVIEW; SERUM SICKNESS; STREPTOCOCCUS PNEUMONIAE; TOOTH COLOR; TOOTH DISEASE; ACUTE DISEASE; ADULT; CLASSIFICATION; CLINICAL TRIAL; DRUG ADMINISTRATION; EXPERT WITNESS; HOSPITALIZATION; INFANT; MICROBIOLOGY; PRESCHOOL CHILD; TREATMENT OUTCOME;

ACUTE DISEASE; ADOLESCENT; ADULT; ANTI-INFECTIVE AGENTS; CHILD, PRESCHOOL; CLINICAL TRIALS; DRUG ADMINISTRATION SCHEDULE; EXPERT TESTIMONY; HUMAN; INFANT; OTITIS MEDIA; SEVERITY OF ILLNESS INDEX; TREATMENT OUTCOME; HUMANS;

EID: 0035989227     PISSN: 14656566     EISSN: None     Source Type: Journal    
DOI: 10.1517/14656566.3.8.1073     Document Type: Review

References (144)

1. Otitis media: Back to basics
2. Treatment of acute otitis media: A controlled study of 142 children
3. Amoxicillin or myringotomy or both for acute otitis media: Results of a randomized clinical trial
4. Penicillin-resistant Streptococcus pneumoniae in acute otitis media: Risk factors, susceptibility patterns and antimicrobial management
5. Final evidence report: Management of otitis media
6. Treatment failure in otitis media: An analysis
7. Persistent acute otitis media: II. Antimicrobial treatment
8. Pathogens isolated during treatment failures in otitis
9. Otitis media. Clinical observations, microbiology, and evaluation of therapy
10. Clinical efficacy of antimicrobial drugs for acute otitis media: Meta-analysis of 5400 children from thirty-three randomized trials
11. Acute otitis media; a new treatment strategy
12. Acute red ear in children: Controlled trial of non-antibiotic treatment in general practice
13. Are antibiotics indicated as initial treatment for children with acute otitis media? A meta-analysis
14. Natural history of untreated otitis media
15. Efficacy of fixed combination antibiotics versus separate components in otitis media. Effectiveness of erythromycin estrolate, triple sulfonamide, ampicillin, erythromycin estolate-triple sulfonamide, and with acute otitis media under two and one-half years of age
16. Therapy of acute otitis media: Myringotomy, antibiotics, or neither? A double blind study in children
17. Co-amoxiclav in recurrent acute otitis media: Placebo controlled study
18. Penicillin in acute otitis media: A double-blind placebo-controlled trial
19. Otitis media treatment in New Zealand general practice
20. Primary care based randomized, double blind trial of amoxicillin versus placebo for acute otitis media in children aged under 2 years
21. Diagnosis and antibiotic treatment of acute otitis media: Report from International Primary Care Network
22. Recurrent and persistent otitis media
23. Cefprozil treatment of persistent and recurrent acute otitis media
24. Efficacy of auralgan for treating ear pain in children with acute otitis media
25. Intranasal fluticasone propionate does not prevent acute otitis media during viral upper respiratory infection in children
26. Efficacy of amoxicillin with and without decongestant-antihistamine for otitis media with effusion in children. Results of a double-blind randomized trial
27. Evaluating the need, timing and best choice antibiotic therapy for acute otitis media and tonsillopharyngitis infections in children
28. Antibiotic-resistant Streptococcus pneumoniae in acute otitis media: Overview and update
29. Causative pathogens, antibiotic resistance and therapeutic considerations in acute otitis media
30. Prevalence of antimicrobial-resistant pathogens in middle ear fluid: Multinational study of 917 children with acute otitis media
31. Antimicrobial resistance among clinical isolates of Streptococcus pneumoniae in the United States during 1999-2000, including a comparison of resistance rates since 1994-1995
32. Six year multicenter surveillance of invasive pneumococcal infections in children
33. Management of infections caused by antibiotic-resistant Streptococcus pneumoniae
34. Activity of oral antibiotics in middle ear and sinus infections caused by penicillin-resistant Streptococcus pneumoniae: Implications for treatment
35. Increasing incidence of penicillin- and ampicillin-resistant middle ear pathogens
36. Confronting multidrug resistance. A role for each of us
37. Increased rate of isolation of penicillin-resistant Streptococcus pneumoniae in a children's hospital and in vitro susceptibilities to antibiotics of potential therapeutic use
38. Trends in antibiotic resistance of respiratory pathogens: An analysis and commentary on a collaborative surveillance study
39. The clinical relevance of invitro resistance to penicillin, ampicillin, amoxicillin and alternative agents for the treatment of community-acquired pneumonia caused by Streptococcus pneumoniae, catarrhalis
40. Acute otitis media: Part II. Treatment in an era of increasing antibiotic resistance
41. Comparative efficacy of ampicillin and trimethoprim-sulfamethoxazole in otitis media
42. A comparison between co-trimoxazole and amoxicillin in the treatment of acute otitis media in general practice
43. Trimethoprim-sulfamethoxazole v. amoxicillin in the treatment of acute otitis media
44. Twice-daily antibiotics in the treatment of acute otitis media: Trimethoprim-sulfamethoxazole versus amoxicillin-clavulanate
45. Trimethoprim-sulfamethoxazole compared with ampicillin in the treatment of acute otitis media
46. Cefdinir versus amoxicillin/clavulanic acid in the treatment of suppurative acute otitis media in children
47. Comparative trial of cefprozil versus amoxicillin clavulanate potassium in the treatment of children with acute otitis media with effusion
48. Cefprozil versus amoxicillin/clavulanate in the treatment of acute otitis media
49. Comparative study of the safety and efficacy of clarithromycin and amoxicillin-clavulanate in the treatment of acute otitis media in children
50. Efficacy of twice-daily dosing of amoxicillin/clavulanate in acute otitis media children
51. Comparative safety and efficacy of cefdinir versus amoxicillin/clavulanate acid for treatment of suppurative acute otitis media in children
52. Acute otitis media in children: A study of nasopharyngeal carriage of potential pathogens and therapeutic efficacy of cefixime and amoxicillin-clavulanate
53. Bacteriologic efficacies of oral azithromycin and oral cefaclor in treatment of acute otitis media in infants and young children
54. Efficacy and safety of amoxicillin/clavulanate (Augmentin) twice daily versus three times daily in the treatment of acute otitis media in children
55. Comparative evaluation of loracarbef and amoxicillin-clavulanate for acute otitis media
56. Comparative efficacy and safety of cefprozil and amoxicillin/clavulanate in the treatment of acute otitis media in children
57. Twice daily cefpodoxime proxetil compared with thrice daily amoxicillin/clavulanic acid for treatment of acute otitis media in children
58. Clinical comparison of cefuroxime axetil suspension and amoxicillin/clavulanate suspension in the treatment of pediatric patients with acute otitis media with effusion
59. Clinical and bacteriological efficacy of amoxicillin/clavulanate (Spektramox) and cefaclor (Kefolor) in children with recurrent AOM or therapy failure
60. Evaluation of amoxicillin clavulanate twice daily versus thrice daily in the treatment of otitis media in children
61. Amoxicillin-clavulanate potassium compared with cefaclor for acute otitis media in infants and children
62. Clinical efficacy of amoxicillin/clavulanic acid and cefaclor in acute otitis media
63. Efficacy of 20- versus 10-day antimicrobial treatment for acute otitis media
64. A randomized controlled trial of amoxicillin plus clavulanate compared with cefaclor for treatment of acute otitis media
65. Comparative safety and efficacy of clarithromycin and amoxicillin/clavulanate in the treatment of acute otitis media in children
66. Comparison of cefuroxime axetil, cefaclor, and amoxicillin-clavulanate potassium suspensions in acute otitis media in infants and children
67. Treatment of otitis media with cefuroxime axetil
68. Comparison of cefpod-oxime proxetil and cefixime in the treat-ment of acute otitis media in infants and children
69. Comparison of ceftriaxone and trimethoprim-sulfamethoxazole for acute otitis media
70. Comparative efficacies of erythromycin-sulfisoxazole and cefaclor in acute otitis media: A double blind randomized trial
71. A controlled trial of cefaclor versus amoxicillin for treatment of acute otitis media in early infancy
72. An open comparative study of the efficacy and safety of sultamicillin versus cefaclor in the treatment of acute otitis media in children
73. Comparison of cefaclor and trimethoprim-sulfamethoxazole in the treatment of acute otitis media
74. Multinational multicenter controlled trial comparing Ceftibuten with cefaclor for the treatment of acute otitis media
75. Comparison of the efficacy and tolerability of once daily Ceftibuten and twice-daily cefprozil in the treatment of children with acute otitis media
76. Comparative study of cefuroxime axetil suspension and amoxicillin syrup in the treatment of acute otitis media in general practice
77. Bacteriologic response to oral cephalosporins: Are established susceptibility breakpoints appropriate in the case of acute otitis media?
78. A trial comparing cefaclor with co-trimoxazole in the treatment of acute otitis media
79. Loracarbef (LY163892) versus amoxicillin-clavulanate in the treatment of bacterial acute otitis media with effusion
80. Comparative United States and European trials of loracarbef in the treatment of acute otitis media
81. Cefetamet pivoxil versus cefaclor in the treatment of acute otitis media in children
82. Cefaclor v amoxicillin in treatment of acute otitis media
83. Clarithromycin and cefaclor suspensions in the treatment of acute otitis media in children
84. Comparison of the efficacy, safety and acceptability of cefixime and amoxicillin/clavulanate in acute otitis media
85. Loracarbef versus clarithromycin in children with acute otitis media with effusion
86. Single-dose intramuscular ceftriaxone for acute otitis media in children
87. Microbiologic and clinical aspects of a trial of once daily cefixime compared with twice daily cefaclor for treatment of acute otitis media in infants and children
88. In vivo sensitivity test in otitis media: Efficacy of antibiotics
89. Bacteriologic and clinical efficacy of cefixime compared with amoxicillin in acute otitis media
90. Treatment of otitis media in children. A comparison between cefaclor and amoxicillin
91. Cefixime compared with amoxicillin for treatment of acute otitis media
92. Comparison of amoxicillin with second and third generation cephalosporins in the treatment of acute otitis media
93. Cefixime versus cefaclor in the treatment of acute otitis media in infants and children
94. A general practice comparative study of a new third-generation oral cephalosporin, cefixime, with amoxicillin in the treatment of acute paediatric otitis media
95. Cefixime in the treatment of respiratory and urinary tract infections
96. Comparative treatment trial of augmentin versus cefaclor for acute otitis media with effusion
97. Comparison of cefaclor and amoxicillin for acute otitis media with effusion
98. Efficacy of ceftibuten compared with amoxicillin for otitis media with effusion in infants and children
99. Duration of effusion after antibiotic treatment for acute otitis media: Comparison of cefaclor and amoxicillin
100. A comparative evaluation of cefaclor and amoxicillin in the treatment of acute otitis media
101. A randomized controlled trial of cefaclor compared with trimethoprim-sulfamethoxazole for treatment of acute otitis media
102. Cefaclor in treatment of otitis media and pharyngitis in children
103. Randomized, open label, multicenter trial of cefixime compared with amoxicillin for treatment of acute otitis media with effusion
104. Multicenter controlled trial comparing ceftibuten with amoxicillin/clavulanate in the empiric treatment of acute otitis media
105. Cefpodoxime proxetil compared with amoxicillin-clavulanate for the treatment of otitis media
106. Efficacy of cefixime in the treatment of acute otitis media in children
107. Double-blind comparison of cefixime and cefaclor in the treatment of acute otitis media in children
108. Evaluation of five days of cefaclor versus ten days of amoxicillin therapy in acute otitis media
109. Cefixime versus amoxicillin in the treatment of acute otitis media in infants and children
110. Cefetamet pivoxil in pediatric otitis media
111. Cefixime versus cefaclor in the treatment of acute otitis media in children: A randomized, comparative study
112. A randomized, observer-blind trial of amoxicillin/clavulanate versus cefaclor in the treatment of children with acute otitis media
113. Cefuroxime axetil in the treatment of acute otitis media in children
114. Comparison of once daily cefpodoxime proxetil suspension and thrice daily cefaclor suspension in the treatment of acute otitis media in children
115. Comparison of cefaclor and cefuroxime axetil in the treatment of acute otitis media with effusion in children who failed amoxicillin therapy
116. Single intramuscular dose of ceftriaxone as compared to 7-day amoxicillin therapy for acute otitis media in children. A double blind clinical trial
117. Quantitative comparison of adverse reactions to cefaclor versus amoxicillin in surveillance study
118. Concentrations of cefpodoxime in plasma and lung tissue after a single oral dose of cefpodoxime proxetil
119. Pharmacodynamics and pharmacokinetics of cefdinir, an oral extended-spectrum cephalosporin
120. Clarithromycin versus amoxicillin suspensions in the treatment of pediatric patients with acute otitis media
121. Acute otitis media in older children and adults treated with phenoxymethyl penicillin or erythromycin stearate. Bacteriological and immunological aspects
122. Comparative trial of 3-day azithromycin versus 10-day amoxicillin/clavulanate potassium in the treatment of children with acute otitis media
123. Comparative trial of 3 days of azithromycin versus 10 days of clarithromycin in the treatment of children with acute otitis media with effusion
124. A multicenter, open label trial of azithromycin versus amoxicillin/clavulanate for the management of acute otitis media in children
125. A comparative study of clarithromycin and amoxicillin suspensions in the treatment of pediatric patients with acute otitis media
126. Bacteriologic and clinical efficacy of amoxicillin/clavulanate versus azithromycin in acute otitis media
127. Comparison of azithromycin and co-amoxiclav in the treatment of otitis media in children
128. Azithromycin: 3-day versus 5-day course in the treatment of respiratory tract infections in children
129. A multicenter, randomized, open label comparison of azithromycin and amoxicillin/clavulanate in acute otitis media among children attending day care or school
130. A multicenter, open label trial of azithromycin for the treatment of children with acute otitis media
131. A multicenter, double blind comparison of azithromycin and amoxicillin/clavulanate for the treatment of acute otitis media in children
132. A comparative study of azithromycin and amoxicillin in paediatric patients with acute otitis media
133. An open comparative study of azithromycin and roxithromycin in the treatment of acute upper respiratory tract infections
134. Azithromycin in upper respiratory tract infections: A clinical trial in children with otitis media
135. Comparative safety and efficacy of clarithromycin and azithromycin suspensions in the short course treatment of children with acute otitis media
136. An open study to compare azithromycin with cefaclor in the treatment of children with acute otitis media
137. Multicentre evaluation of azithromycin in comparison with co-amoxiclav for the treatment of acute otitis media in children
138. Acute otitis media: Management and surveillance in an era of pneumococcal resistance - A report from the Drug-resistant Streptococcus pneumoniae Therapeutic Working Group
139. Controversies in the medical management of persistent and recurrent acute otitis media
140. Microbiologic efficacy of antibacterial drugs for acute otitis media
141. Shortened course of antibiotic therapy for acute otitis media, sinusitis and tonsillopharyngitis
142. Treatment of acute otitis media with a shortened course of antibiotics: A meta-analysis
143. Short course antibiotic therapy for respiratory infections: A review of the evidence
144. A prospective observational study of 5-, 7-, and 10-day antibiotic treatment for acute otitis media