Role of substance P in the vascular response of nasal mucosa in nasal allergy

Annals of Otology, Rhinology and Laryngology

Volumn 105, Issue 8, 1996, Pages 648-653

  Konno, Akiyoshi ^a   Hanazawa, Toyoyuki ^a   Numata, Tsutomu ^a   Nagata, Hiroshi ^a   Terada, Nobuhisa ^a   Motosugi, Hideaki ^a  

^a CHIBA UNIVERSITY   (Japan)

Author keywords

mucosal blood flow; nasal airway resistance; nasal allergy; substance P.

Indexed keywords

CALCITONIN GENE RELATED PEPTIDE RECEPTOR; CAPSAICIN; SUBSTANCE P;

ADOLESCENT; ADULT; AIRWAY RESISTANCE; ANTIGEN ANTIBODY COMPLEX; ARTICLE; BLOOD VESSEL REACTIVITY; CLINICAL ARTICLE; DOSE RESPONSE; FEMALE; HUMAN; HUMAN TISSUE; IMMUNOREACTIVITY; MALE; NOSE ALLERGY; PRIORITY JOURNAL; SKIN TEST;

EID: 9444250472     PISSN: 00034894     EISSN: None     Source Type: Journal    
DOI: 10.1177/000348949610500811     Document Type: Article

References (25)

1. Lundblad L, Lundberg JM, Brodin E, Anggärd A. Origin and distribution of capsaicin-sensitive substance P-immunoreactive nerves in the nasal mucosa. Acta Otolaryngol (Stockh) 1983;96:485-93.
2. Stjärne P, Lundblad L, Anggärd A, Hökfelt T, Lundberg JM. Tachykinins and calcitonin gene-related peptide: coexistence in sensory nerves of the nasal mucosa and vascular effects compared to capsaicin. Cell Tissue Res 1989;256:439-46.
3. Uddman R, Malm L, Sundler F. Substance P-containing nerve fibers in the nasal mucosa. Arch Otorhinolaryngol 1983;238: 9-16.
4. Holtzer P. Local effector functions of capsaicin-sensitive sensory nerve endings: involvement of tachykinins, calcitonin gene-related peptide and other neuropeptides. Neuroscience 1988;24:739-68.
5. Lundblad L. Protective reflexes and vascular effects in the nasal mucosa elicited by activation of capsaicin sensitive substance P-immunoreactive trigeminal neurons. Acta Physiol Scand Suppl 1984(suppl 529).
6. Lundblad L, Anggärd A, Lundberg JM. Effects of antidromic trigeminal nerve stimulation in relation to parasympathetic vasodilatation in cat nasal mucosa. Acta Physiol Scand 1983;119: 7-13.
7. McCusker MT, Chung KF, Roberts NM, Barnes PJ. Effect of topical capsaicin on the cutaneous response to inflammatory mediators and to antigen in man. J Allergy Clin Immunol 1989; 83:118-24.
8. Konno A, Nagata H, Nomoto M, Motosugi H, Terada N. Role of capsaicin-sensitive trigeminal nerves in development of hyperreactive nasal symptoms in guinea pig model of nasal allergy. Ann Otol Rhinol Laryngol 1995;104:730-5.
9. Barnes PJ. Asthma as an axon reflex. Lancet 1986;ii:242-5.
10. Payan DG, Levine JD, Goetzl EJ. Modulation of immunity and hypersensitivity by sensory neuropeptides. J Immunol 1984;132:1601-4.
11. Braunstein G, Fajac I, Lacsonique J, Frossard N. Clinical and inflammatory responses to exogenous tachykinins in allergic rhinitis. Am Rev Respir Dis 1991;144:630-5.
12. Devillier P, Dessanges JF, Rakotosikanaka F, et al. Nasal response to substance P and methacholine in subjects with and without allergic rhinitis. Eur Respir J 1988;1:356-61.
13. Miadonna A, Tedeschi A, Leggieri E, et al. Activity of substance P on human skin and nasal airways. Ann Allergy 1988;61:220-3.
14. Nieber K, Baumgarten C, Witzel A, et al. The possible role of substance P in the allergic reaction, based on two different provocation models. Int Arch Allergy Appl Immunol 1991;94: 334-8.
15. Walker KB, Serwonska MH, Valone FH, et al. Distinctive patterns of release of neuroendocrine peptides after nasal challenge of allergic subjects with ryegrass antigen. J Clin Immunol 1988;8:108-13.
16. Wolf G, Loidt D, Saria A, Gamse R. Änderungen des nasalen Volumenstromes nach lokaler Applikation des Neuropeptides Substanz-P und von Capsaicin. Laryngol Rhinol Otol (Stuttg) 1987;66:412-5.
17. Okuda M. Fundamental and clinical studies on nasal allergy. Otologia Fukuoka 1974;20:297-344.
18. Olsson P, Bende M, Ohlin P. The laser Doppler flow meter for measuring microcirculation in human nasal mucosa. Acta Otolaryngol (Stockh) 1985;99:133-9.
19. Terada N, Ando H, Ito E, et al. Nasal allergy and leukotriene - kinetics of peptide leukotrienes and inflammatory cells in nasal lavage fluid after antigen challenge. J Otolaryngol Jpn 1989;92:1337-44.
20. Chaen T, Watanabe N, Mogi G, Mori K, Takeyama M. Substance P and vasoactive intestinal peptide in nasal secretions and plasma from patients with nasal allergy. Ann Otol Rhinol Laryngol 1993;102:16-21.
21. Tonnesen P, Hindberg I, Schaffalitzky de Mackadell OB, Mygind N. Effect of nasal allergen challenge on serotonin, substance P and vasoactive intestinal peptide in plasma and nasal secretions. Allergy 1988;43:310-7.
22. Foreman JC, Jordan CC, Oehme P, Renner H. Structure-activity relationship for some substance P-related peptides that cause wheal and flare reactions in human skin. J Physiol (Lond) 1983;335:449-65.
23. Hagermark O, Hokfelt T, Pernow B. Flare and itch induced by substance P in human skin. J Invest Dermatol 1978; 71:233-5.
24. Barnes PJ, Brown MJ, Dollery CT, Fuller RW, Heavey DJ, Ind RW. Histamine is released from skin by substance P but does not act as the final vasodilator in the axon reflex. Br J Pharmacol 1986;88:741-5.
25. Yamaguchi M. Mucosal blood volume in the human nose. Measurement with a spectrophotometric analysis. Pract Otol (Kyoto) 1991(suppl 44):1-39.