Long-lasting increased excitability differs in dentate gyrus vs. CA1 in freely moving chronic epileptic rats after electrically induced status epilepticus

Hippocampus

Volumn 12, Issue 3, 2002, Pages 311-324

  Gorter, Jan A ^a,b   Van Vliet, Erwin A ^a   Aronica, Eleonora ^b,c   Lopes Da Silva, Fernando H ^a,b  

^a UNIVERSITY OF AMSTERDAM   (Netherlands)

^b STICHTING EPILEPSIE INSTELLINGEN NEDERLAND SEIN   (Netherlands)

^c UNIVERSITY OF AMSTERDAM   (Netherlands)

Author keywords

Electrical stimulation; Epilepsy; Field potential; Paired pulse response; Sprouting

Indexed keywords

KETAMINE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT; PARVALBUMIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; BRAIN NERVE CELL; BRAIN REGION; CELL GRANULE; CHRONICITY; CONTROLLED STUDY; DENTATE GYRUS; ELECTRIC POTENTIAL; EPILEPTIC STATE; EVOKED RESPONSE; GABAERGIC SYSTEM; IMMUNOREACTIVITY; LATENT PERIOD; MALE; MOSSY FIBER; NERVE CELL NETWORK; NERVE EXCITABILITY; NERVE STIMULATION; NONHUMAN; PRIORITY JOURNAL; RAT; RECURRENT DISEASE; REINNERVATION; REVIEW; SEIZURE; SURVIVAL; ANIMAL; ARTICLE; CHRONIC DISEASE; ELECTROENCEPHALOGRAPHY; ELECTROSTIMULATION; EPILEPSY; EXCITATORY POSTSYNAPTIC POTENTIAL; HIPPOCAMPUS; METHODOLOGY; PATHOPHYSIOLOGY; SPRAGUE DAWLEY RAT; STAINING; TIME;

ANIMAL; CHRONIC DISEASE; DENTATE GYRUS; ELECTRIC STIMULATION; ELECTROENCEPHALOGRAPHY; EPILEPSY; EXCITATORY POSTSYNAPTIC POTENTIALS; HIPPOCAMPUS; MALE; PARVALBUMINS; RATS; RATS, SPRAGUE-DAWLEY; STAINING AND LABELING; STATUS EPILEPTICUS; SUPPORT, NON-U.S. GOV'T; TIME FACTORS; ANIMALS;

EID: 0035986245     PISSN: 10509631     EISSN: None     Source Type: Journal    
DOI: 10.1002/hipo.1100     Document Type: Review

References (46)

1. GABAergic cells are the major postsynaptic targets of mossy fibers in the rat hippocampus
2. Upregulation of metabotropic glutamate receptor subtype mGluR3 and mGluR5 in reactive astrocytes in a rat model of mesial temporal lobe epilepsy
3. Functional anatomy of spontaneous seizures in a rat model of limbic epilepsy
4. Network properties of the dentate gyrus in epileptic rats with hilar neuron loss and granule cell axon reorganization
5. Neuron loss, granule cell axon reorganization, and functional changes in the dentate gyrus of epileptic kainate-treated rats
6. Zinc-induced collapse of augmented inhibition by GABA in a temporal lobe epilepsy model
7. Septotemporal variation of the supragranular projection of the mossy fiber pathway in the dentate gyrus of normal and kindled rats
8. Long-term loss of paired pulse inhibition in the kainic acid-lesioned hippocampus of the rat
9. Sprouting of GABAergic and mossy fiber axons in dentate gyrus following intrahippocampal kainate in the rat
10. Preferential neuronal loss in layer III of the medial entorhinal cortex in rat models of temporal lobe epilepsy
11. Newly formed excitatory pathways provide a substrate for hyperexcitability in experimental temporal lobe epilepsy
12. Spatio-temporal evolution of cell death in the hippocampus and entorhinal cortex in the post-status epilepticus model
13. Progression of spontaneous seizures after status epilepticus is associated with mossy fibre sprouting and extensive bilateral loss of hilar parvalbumin and somatostatin-immunoreactive neurons
14. Kainic acid-induced seizures enhance dentate gyrus inhibition by downregulation of GABA(B) receptors
15. The dentate gyrus as a regulated gate for the propagation of epileptiform activity
16. Assessment of inhibition and epileptiform activity in the septal dentate gyrus of freely behaving rats during the first week after kainate treatment
17. Altered hippocampal gene expression prior to the onset of spontaneous seizures in the rat post status epilepticus model
18. Hippocampal plasticity involves extensive gene induction and multiple cellular mechanisms
19. Changes in local evoked potentials in the rat hippocampus (CA1) during kindling epileptogenesis
20. Decrease in GABA immunoreactivity and alteration of GABA metabolism after kindling in the rat hippocampus
21. A long-lasting decrease in the inhibitory effect of GABA on glutamate responses of hippocampal pyramidal neurons induced by kindling epileptogenesis
22. Hippocampal kindling leads to different changes in paired-pulse depression of local evoked field potentials in CA1 area and in fascia dentata
23. Characterization of target cells for aberrant mossy fiber collaterals in the dentate gyrus of epileptic rat
24. Self-sustaining limbic status epilepticus induced by "continuous" hippocampal stimulation: Electrographic and behavioral characteristics
25. The dentate gyrus as a control point for seizures in the hippocampus and beyond
26. Changes in excitatory neurotransmission in the CA1 region and dentate gyrus in a chronic model of temporal lobe epilepsy
27. Delayed cell death in the contralateral hippocampus following kainate injection into the CA3 subfield
28. Ontogeny of altered synaptic function in a rat model of chronic temporal lobe epilepsy
29. Changes in inhibitory neurotransmission in the CA1 region and dentate gyrus in a chronic model of temporal lobe epilepsy
30. Alteration in dentate neuronal activities associated with perforant path kindling. III. Enhancement of synaptic inhibition
31. In contrast to kindled seizures, the frequency of spontaneous epilepsy in the limbic status model correlates with greater aberrant fascia dentata N-methyl-D-aspartate, AMPA and GABA(A) receptors
32. Circuit mechanisms of seizures in the pilocarpine model of chronic epilepsy: Cell loss and mossy fiber sprouting
33. The balance between excitation and inhibition in dentate granule cells and its role in epilepsy
34. A new model of chronic temporal lobe epilepsy induced by electrical stimulation of the amygdala in rat
35. Increased number of synaptic GABA(A) receptors underlies potentiation at hippocampal inhibitory synapses
36. Axonal sprouting of CA1 pyramidal cells in hyperexcitable hippocampal slices of kainate-treated rats
37. Activation of the NMDA receptor: A correlate in the dentate gyrus field potential and its relationship to long-term potentiation and kindling
38. Regional heterogeneity of pathophysiological alterations in CA1 and dentate gyrus in a chronic model of temporal lobe epilepsy
39. A simplified Timm stain procedure compatible with formaldehyde fixation and routine paraffin embedding of rat brain
40. Permanently altered hippocampal structure, excitability, and inhibition after experimental status epilepticus in the rat: The "dormant basket cell" hypothesis and its possible relevance to temporal lobe epilepsy
41. Possible functional consequences of synaptic reorganization in the dentate gyrus of kainate-treated rats
42. Dentate granule cells form novel basal dendrites in a rat model of temporal lobe epilepsy
43. Long-term structural and functional alterations induced in the hippocampus by kindling: Implications for memory dysfunction and the development of epilepsy
44. Opposite changes in GABAA receptor function in the CA1-3 area and fascia dentata of kindled rat hippocampus
45. Chronic epilepsy with damage restricted to the hippocampus: Possible mechanisms
46. Electrographic seizures and new recurrent excitatory circuits in the dentate gyrus of hippocampal slices from kainate-treated epileptic rats