The absence of factor V Leiden mutation in Malays with recurrent spontaneous abortions

Australian and New Zealand Journal of Obstetrics and Gynaecology

Volumn 42, Issue 2, 2002, Pages 164-166

  Yusoff, Narazah Mohd ^a   Abdullah, Wan Zaidah ^a   Ghazali, Selamah ^a   Othman, Mohd Shukri ^a   Baba, Abdul Aziz ^a   Abdullah, Norazmi ^b   Isa, Mohd Nizam ^a   Chong, Chan Li ^b,c  

^a SCHOOL OF PHYSICS   (Malaysia)

^b UNIVERSITY OF HONG KONG   (Hong Kong)

^c Department of Pathology ^*  (Malaysia)

Author keywords

[No Author keywords available]

Indexed keywords

BLOOD CLOTTING FACTOR 5 LEIDEN; GENE PRODUCT; BLOOD CLOTTING FACTOR 5;

ANAMNESIS; ARTICLE; CASE CONTROL STUDY; CONTROLLED STUDY; DISEASE ASSOCIATION; FEMALE; FIRST TRIMESTER PREGNANCY; GENE AMPLIFICATION; GENE MUTATION; HUMAN; MAJOR CLINICAL STUDY; MALAYSIA; PARITY; PATHOGENESIS; PEDIATRIC HOSPITAL; POLYMERASE CHAIN REACTION; PREVALENCE; PRIORITY JOURNAL; PROSPECTIVE STUDY; PROTEIN DEGRADATION; RECURRENT ABORTION; SECOND TRIMESTER PREGNANCY; SPONTANEOUS ABORTION; UNIVERSITY HOSPITAL; ADOLESCENT; ADULT; ALLELE; COMPARATIVE STUDY; GENETIC PREDISPOSITION; GENETICS; INCIDENCE; MOLECULAR GENETICS; NUCLEOTIDE SEQUENCE; POINT MUTATION; PREGNANCY; RECURRENT DISEASE; REFERENCE VALUE; RISK FACTOR;

ABORTION, HABITUAL; ADOLESCENT; ADULT; ALLELES; BASE SEQUENCE; CASE-CONTROL STUDIES; FACTOR V; FEMALE; GENETIC PREDISPOSITION TO DISEASE; HUMANS; INCIDENCE; MALAYSIA; MOLECULAR SEQUENCE DATA; POINT MUTATION; POLYMERASE CHAIN REACTION; PREGNANCY; PREGNANCY TRIMESTER, FIRST; PREGNANCY TRIMESTER, SECOND; PROSPECTIVE STUDIES; RECURRENCE; REFERENCE VALUES; RISK FACTORS;

EID: 0035985241     PISSN: 00048666     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.0004-8666.2002.00164.x     Document Type: Article

References (15)

1. Familial thrombophilia due to a previously unrecognized mechanism characterized by poor anticoagulant response to activated protein C: Prediction of a cofactor to activated protein C
2. Mutation in blood coagulation factor V associated with resistance to activated protein C
3. The population genetics of factor V Leiden (Arg506 Gln)
4. Resistance to Activated Protein C and Arg 506 Gln Factor V mutation are uncommon in eastern Asian populations
5. High risk of thrombosis in patients homozygous for factor V Leiden (activated protein C resistance)
6. Activated protein C resistance: A study among 60 thromboembolic patients in the Singapore population
7. Activated protein C resistance can be associated with recurrent fetal loss
8. Placental thrombosis and second trimester miscarriage in association with activated protein C resistance
9. Factor V Leiden is associated with repeated and recurrent unexplained fetal loss
10. First-trimester repeated abortion is not associated with activated protein C resistance
11. The factor V Leiden mutation is not a common cause of recurrent miscarriage
12. Factor V as a risk factor for miscarriage and reduced fertility
13. A simple 15-minute PCR sample preparation from whole blood
14. The factor V Leiden mutation in Japanese couples with recurrent spontaneous abortion
15. Fetal carriers of the factor V Leiden mutation are prone to miscarriage and placental infarction