Extracellular ATP and UTP activate the protein kinase B/Akt cascade via the P2Y2 purinoceptor in renal mesangial cells

British Journal of Pharmacology

Volumn 136, Issue 4, 2002, Pages 520-529

  Huwiler, Andrea ^a   Rölz, Waltraud ^a   Dorsch, Simone ^a   Ren, Shuyu ^a   Pfeilschifter, Josef ^a  

^a UNIVERSITY HOSPITAL FRANKFURT   (Germany)

Author keywords

Apoptosis; ATP; Mesangial cell; PDK; PI 3 kinase; Protein kinase B Akt; UTP

Indexed keywords

ADENOSINE TRIPHOSPHATE; AKT1 PROTEIN, RAT; ARACHIDONIC ACID; ISOENZYME; ONCOPROTEIN; PERTUSSIS TOXIN; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; PROTEIN SERINE THREONINE KINASE; PROTEIN TYROSINE KINASE; PURINE P2 RECEPTOR; PURINE P2Y2 RECEPTOR; SURAMIN; URIDINE TRIPHOSPHATE; 2 MORPHOLINO 8 PHENYLCHROMONE; INHIBITORY GUANINE NUCLEOTIDE BINDING PROTEIN; NUCLEOTIDE DERIVATIVE; PROTEIN KINASE INHIBITOR; PURINE ANTAGONIST; PURINE P2Y RECEPTOR; SERINE; THREONINE;

ANALYSIS OF VARIANCE; ANIMAL; APOPTOSIS; ARTICLE; CELL CULTURE; CELL DIVISION; CYTOLOGY; DRUG EFFECT; ENZYME ACTIVATION; EXTRACELLULAR SPACE; MESANGIUM; METABOLISM; PHYSIOLOGY; RAT; WESTERN BLOTTING; ANIMAL CELL; CELL STIMULATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; KIDNEY CELL; MESANGIUM CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ADENOSINE TRIPHOSPHATE; ANALYSIS OF VARIANCE; ANIMALS; APOPTOSIS; ARACHIDONIC ACID; BLOTTING, WESTERN; CELL DIVISION; CELLS, CULTURED; ENZYME ACTIVATION; EXTRACELLULAR SPACE; GLOMERULAR MESANGIUM; ISOENZYMES; PERTUSSIS TOXIN; PROTEIN-SERINE-THREONINE KINASES; PROTEIN-TYROSINE KINASES; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-AKT; RATS; RECEPTORS, PURINERGIC P2; SURAMIN; URIDINE TRIPHOSPHATE; ANIMAL; PROTEIN-TYROSINE KINASE; SUPPORT, NON-U.S. GOV'T;

EID: 0035984934     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0704748     Document Type: Article

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