Structural and functional properties of two mutants of lecithin- cholesterol acyltransferase (T123I and N228K)

Journal of Biological Chemistry

Volumn 273, Issue 49, 1998, Pages 32561-32567

  Adimoolam, Shanthi ^a   Jin, Lihua ^a   Grabbe, Edith ^b   Shieh, Jeng Jong ^b   Jonas, Ana ^a  

^a UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

^b MONSANTO COMPANY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PHOSPHATIDYLCHOLINE STEROL ACYLTRANSFERASE;

ARTICLE; CHO CELL; CONFORMATIONAL TRANSITION; ENZYME ACTIVATION; ENZYME CONFORMATION; ENZYME GLYCOSYLATION; ENZYME INDUCTION; ENZYME SPECIFICITY; EQUILIBRIUM CONSTANT; GENE MUTATION; MOLECULAR STABILITY; NONHUMAN; PRIORITY JOURNAL;

ANIMALS; BASE SEQUENCE; CIRCULAR DICHROISM; COS CELLS; CRICETINAE; CRICETULUS; DNA PRIMERS; HUMANS; KINETICS; MUTAGENESIS; PHOSPHATIDYLCHOLINE-STEROL O-ACYLTRANSFERASE; PROTEIN CONFORMATION; SPECTROMETRY, FLUORESCENCE; STRUCTURE-ACTIVITY RELATIONSHIP; SURFACE PLASMON RESONANCE;

CRICETINAE; CRICETULUS GRISEUS;

EID: 0032484133     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.273.49.32561     Document Type: Article

References (42)

1. Norum, K. R., and Gjone, E. (1967) Scand. J. Clin. Lab. Invest. 20, 231-243
2. Skretting, G., Blomhoff, J. P., Solheim, J., and Prydz, H. (1992) FEBS Lett. 309, 307-310
3. Kuivenhoven, J. A., Pritchard, H., Hill, J., Frohlich, J., Assmann, G., and Kastelein, J. (1997) J. Lipid Res. 38, 191-205
4. Glomset, J. A., Assmann, G., Gjone, E., and Nurum, K. R. (1989) in The Metabolic and Molecular Bases of Inherited Disease (Scriver, C. R., Beaudet, A. L., Sly, W. S., Stanbury, J. B., Wyngaarden, J. B., and Fredrickson, D. S., eds) pp. 1933-1951, McGraw-Hill Inc., New York
5. Assmann, G., von Eckardstein, A., and Funke, H. (1991) Curr. Opin. Lipidol. 2, 110-117
6. Carlson, L. A., and Holmquist, L. (1983) Acta Med. Scand. 213, 177-182
7. Klein, H.-G., Lohse, P., Duverger, N., Albers, J. J., Rader, D. J., Zech, L. A., Santamarina-Fojo, S., and Brewer, H. B., Jr. (1993) J. Lipid Res. 34, 49-58
8. Qu, S., Fan, H., Blanco-Vaca, F., and Pownall, H. J. (1995) J. Lipid Res. 36, 967-974
9. Klein, H.-G., Duverger, N., Albers, J. J., Marcovina, S. M., Brewer, H. B., Jr., and Santamarina-Fojo, S. (1995) J. Biol. Chem. 270, 9443-9447
10. O, K., Hill, J. S., Wang, X., and Pritchard, H. P. (1993) J. Lipid Res. 34, 81-88
11. Funke, H., von Eckardstein, A., Pritchard, H. P., Albers, J. J., Kastelein, J. J. P., Droste, C., and Assmann, G. (1991) Proc. Natl. Acad. Sci. U. S. A. 88, 4855-4859
12. Gotoda, T., Yamada, N., Murase, T., Sakuma, M., Murayama, N., Shimano, H., Kozaki, K., Albers, J. J., Yazaki, Y., and Akanuma, Y. (1991) Lancet 338, 778-781
13. Ho, S. N., Hunt, H. D., Horton, R. M., Pullen, J. K., and Pease, L. R. (1989) Gene (Amst.) 77, 51-59
14. Adimoolam, S., Lee, Y.-P., and Jonas, A. (1998) Biochem. Biophys. Res. Commun. 243, 337-341
15. Lee, Y.-P., Adimoolam, S., Liu, M., Subbaiah, P. V., Glenn, K., and Jonas, A. (1997) Biochim. Biophys. Acta 1344, 250-261
16. Kriegler, M. (1990) in Gene Transfer and Expression (Kriegler, M., ed) pp. 96-102, W. H. Freeman & Co., New York
17. Adimoolam, S., and Jonas, A. (1997) Biochem. Biophys. Res. Commun. 232, 783-787
18. Matz, C. E., and Jonas, A. (1982) J. Biol. Chem. 257, 4535-4540
19. Schumaker, V. N., and Puppione, D. L. (1986) Methods Enzymol. 128, 155-170
20. Stokke, K. T., and Norum, K. R. (1971) Scand. J. Clin. Lab. Invest. 27, 21-27
21. Bonelli, F. S., and Jonas, A. (1989) J. Biol. Chem. 264, 14723-14728
22. Jin, L., Lee, Y.-P., and Jonas, A. (1997) J. Lipid Res. 38, 1085-1093
23. Schimke, R. T. (1986) Cancer (Phila.) 57, 1912-1917
24. Andrade, M. A., Chacon, P., Merelo, J. J., and Moran, F. (1993) Protein Eng. 6, 383-390
25. Malmquist, M. (1993) Nature 361, 186-187
26. Jonas, A., Zorich, N. L., Kezdy, K. E., and Trick, W. E. (1987) J. Biol. Chem. 262, 3969-3974
27. McLean, J., Fielding, C., Drayna, D., Dieplinger, H., Baer, B., Kohr, W., Henzel, W., and Lawn, R. (1986) Proc. Natl. Acad. Sci. U. S. A. 83, 2335-2339
28. Francone, O. L., and Fielding, C. J. (1991) Proc. Natl. Acad, Sci. U. S. A. 88, 1716-1720
29. Peelman, F., Vinaimont, N., Verhee, A., Vanloo, B., Verschelde, J.-L., Labeur, C., Seguret-Mace, S., Duverger, N., Hutchinson, G., Vandekerckhove, J., Tavernier, J., and Rosseneu, M. (1998) Protein Sci. 7, 587-599
30. Wang, J., Gebre, A. K., Anderson, R. A., and Parks, J. S. (1997) J. Biol. Chem. 272, 280-286
31. Fielding, C. J., and Fielding, P. E. (1995) J. Lipid Res. 36, 211-228
32. Peelman, F., Goethals, M., Vanloo, B., Labeur, C., Brasseur, R., Vandekerckhove, J., and Rosseneu, M. (1997) Eur. J. Biochem. 249, 708-715
33. Jonas, A., Bolin, D. J., and Bonelli, F. S. (1992) in High Density Lipoproteins and Atherosclerosis III (Miller, N. E., and Tall, A. R., eds) pp. 67-75, Elsevier Science Publishers B. V., Amsterdam
34. Bolin, D. J., and Jonas, A. (1994) J. Biol. Chem. 269, 7429-7434
35. Bolin, D. J., and Jonas, A. (1996) J. Biol. Chem. 271, 19152-19158
36. Lowe, M. E. (1994) Gastroenterology 107, 1524-1536
37. van Tilbeurgh, H., Egloff, M., Martinez, C., Rugani, N., Verger, R., and Cambillau, C. (1993) Nature 362, 814-820
38. Minnich, A., Collet, X., Roghani, A., Cladaras, C., Hamilton, R. L., Fielding, C. J., and Zannis, V. I. (1992) J. Biol. Chem. 267, 16553-16560
39. Sorci-Thomas, M., Kearns, M. W., and Lee, J. P. (1993) J. Biol. Chem. 268, 21403-21409
40. Sorci-Thomas, M. G., Curtiss, L., Parks, J. S., Thomas, M. J., Kearns, M. W., and Landrum, M. (1998) J. Biol. Chem. 273, 11776-11782
41. Jauhiainen, M., and Dolphin, P. J. (1986) J. Biol. Chem. 261, 7032-7043
42. Jain, M. K., Rogers, J., Jahagirdar, D. V., Marecek, J. F., and Ramirez, F. (1986) Biochim. Biophys. Acta 860, 435-447