Characterization of human plasma apolipoprotein E-containing lipoproteins in the high density lipoprotein size range: Focus on pre-β1- LpE, pre-β2-LpE, and α-LpE

Journal of Lipid Research

Volumn 38, Issue 1, 1997, Pages 35-48

  Krimbou, Larbi ^a   Tremblay, Michel ^a   Davignon, Jean ^a   Cohn, Jeffrey S ^a  

^a CLIN RESEARCH INSTITUTE OF MONTREAL   (Canada)

Author keywords

apoE phenotype; coronary artery disease; FPLC

Indexed keywords

APOLIPOPROTEIN E; HIGH DENSITY LIPOPROTEIN;

ARTICLE; CORONARY ARTERY DISEASE; ELECTROPHORETIC MOBILITY; GEL ELECTROPHORESIS; HUMAN; LIPID ANALYSIS; PARTICLE SIZE; PHENOTYPE; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN CONFORMATION;

ADULT; APOLIPOPROTEINS E; CHEMICAL FRACTIONATION; ELECTROPHORESIS, GEL, TWO-DIMENSIONAL; FEMALE; HIGH-DENSITY LIPOPROTEINS, PRE-BETA; HUMANS; LIPOPROTEINS, HDL; MALE; MIDDLE AGED;

EID: 0031036274     PISSN: 00222275     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (51)

1. Gordon, D., and B. M. Rifkind. 1989. Current concepts: high density lipoproteins: the clinical implications of recent studies. N. Engl. J. Med. 321: 1311-1315.
2. Brown, M. S., and J. L. Goldstein, 1983. Lipoprotein metabolism in the macrophage: implications for cholesterol deposition in atherosclerosis. Annu. Review Biochem. 52: 223-261.
3. Tall, A. R. 1990. Plasma high-density lipoproteins: metabolism and relationship to atherogenesis. J. Clin. Invest. 86: 379-384.
4. Fielding, C. J., and P. E. Fielding. 1995. Molecular physiology of reverse cholesterol transport. J. Lipid Res. 36: 211-228.
5. Patsch, J. R., J. B. Karlin, L. W. Scott, L. C. Smith, and A. M. Gotto, Jr. 1983. Inverse relationship between blood levels of high density lipoprotein subfraction 2 and magnitude of postprandial lipemia. Proc. Natl. Acad. Sci. USA. 80: 1449-1453.
6. Parthasarathy, S., J. Barnett, and L. G. Fong. 1990. High-density lipoprotein inhibits the oxidative modification of low-density lipoprotein. Biochim. Biophys. Acta. 1044: 275-283.
7. Cockerill, G. W., K-A. Rye, J. R. Gamble, M. A. Vadas, and P. J. Barter. 1995. High density lipoproteins inhibit cytokine-induced expression of endothelial cell adhesion molecules. Arterioscler. Thromb. Vasc. Biol. 15: 1987-1994.
8. von Eckardstein, A., Y. Huang, and G. Assman. 1994. Physiological role and clinical significance of high-density lipoprotein subclasses. Curr. Opin. Lipidol. 5: 404-416.
9. Leroy, A., J. Dallongeville and J-C. Fruchart. 1995. Apolipoprotein A-I-containing lipoproteins and atherosclerosis. Curr. Opin. Lipidol. 6: 281-285.
10. De Lalla, O. F., and J. W. Gofman. 1954. Ultracentrifugal analysis of serum lipoproteins. Methods Biochem. Anal. 1: 459-478.
11. Blanche, P. J., E. L. Gong, T. M. Forte, and A. V. Nicols. 1981. Characterization of human high-density lipoproteins by gradient gel electrophoresis. Biochim. Biophys. Acta. 665: 408-419.
12. Kunitake, S. T., K. J. La Sala, and J. P. Kane. 1985. Apolipoprotein A-I-containing lipoproteins with pre-beta electrophoretic mobility. J. Lipid Res. 26: 549-555.
13. Castro, G. R., and C.J. Fielding. 1988. Early incorporation of cell-derived cholesterol into pre-β-migrating HDL. Biochemistry. 27: 25-29.
14. Asztalos, B. F., C. H. Sloop, L. Wong, and P. S. Roheim. 1993. Two-dimensional electrophoresis of plasma lipoproteins: recognition of new apoA-I-containing subpopulations. Biochim. Biophys. Acta. 1169: 291-300.
15. 3. Eur. J. Biochem. 143: 467-476.
16. Cheung, M., and J. J. Albers. 1984. Characterization of lipoprotein particles by immunoaffinity chromatography: particles containing A-I and A-II and particles containing A-I but no A-II. J. Biol. Chem. 259: 12201-12209.
17. von Eckardstein, A., Y. Huang, S. Wu, A. S. Sarmadi, S. Schwartz, A. Steinmetz, and G. Assmann. 1995. Lipoproteins containing apolipoprotein A-IV but not apolipoprotein A-I take up and esterify cell-derived cholesterol in plasma. Arterioscler. Thromb. Vasc. Biol. 15: 1755-1763.
18. Mahley, R. W. 1988. Apolipoprotein E: cholesterol transport protein with expanding role in cell biology. Science. 240: 622-630.
19. Bersot, T. P., R. W. Mahley, M. S. Brown, and J. L. Goldstein. 1976. Interaction of swine lipoproteins with the low density lipoprotein receptor in human fibroblasts. J. Biol. Chem. 251: 2395-2398.
20. Kowal, R. C., J. Herz, J. L. Goldstein, V. Esser, and M. S. Brown. 1979. Low density lipoprotein receptor-related protein mediates uptake of cholesteryl esters derived from apoprotein E-enriched lipoproteins. Proc. Natl. Acad. Sci. USA. 86: 5810-5814.
21. Cohn, J. S., M. Tremblay, M. Amiot, D. Bouthillier, M. Roy, J. Genest, Jr., and J. Davignon. 1996. Plasma concentration of apolipoprotein E in intermediate-sized remnant-like lipoproteins in normolipidemic and hyperlipidemic subjects. Arterioscler. Thromb. Vasc. Biol. 16: 149-159.
22. Mahley, R. W., T. L. Innerarity, K. H. Weisgraber, and S. Y. Oh. 1979. Altered metabolism (in vivo and in vitro) of plasma lipoproteins after selective chemical modification of lysine residues of the apoproteins. J. Clin. Invest. 64: 743-750.
23. Thuren, T., K. H. Weisgraber, P. Sisson, and M. Waite. 1992. Role of apolipoprotein E in hepatic lipase-catalyzed hydrolysis of phospholipid in high-density lipoproteins. Biochemistry. 31: 2332-2338.
24. Mitchell, C. D., W. C. King, K. R. Applegate, T. Forte, J. A. Glomset, K. R. Norum, and E. Gjone. 1980. Characterization of apolipoprotein E-rich high density lipoproteins in familial lecithin:cholesterol acyltransferase deficiency. J. Lipid Res. 21: 625-634.
25. Zorich, N., A. Jonas, and H. J. Pownall. 1985. Activation of lecithin:cholesterol acyltransferase by human apolipoprotein E in discoidal complexes with lipids. J. Biol. Chem. 260: 8831-8837.
26. Yamashita, S., D. L. Sprecher, N. Sakai, Y. Matsuzawa, S. Tarui, and D. Y. Hui. 1990. Accumulation of apolipoprotein E-rich high density lipoproteins in hyperalphalipoproteinemic human subjects with plasma cholesteryl ester transfer protein deficiency. J. Clin. Invest. 86: 688-695.
27. Blum C. B. 1982. Dynamics of apolipoprotein E metabolism in humans. J. Lipid Res. 23: 1308-1316.
28. Huang, Y., A. von Eckardstein, S. Wu, N. Maeda, and G. Assmann. 1994. A plasma lipoprotein containing only apolipoprotein E and with γ mobility on electrophoresis releases cholesterol from cells. Proc. Natl. Acad. Sci. USA. 91: 1834-1838.
29. Huang, Y., A. von Eckardstein, S. Wu, and G. Assmann. 1995. Effects of the apolipoprotein E polymorphism on uptake and transfer of cell-derived cholesterol in plasma. J. Clin. Invest. 96: 2693-2701.
30. 4. Nature. 227: 680-685.
31. Salacinski, P. R., C. McLean, J. E. Sykes, V. V. Clement-Jones, and P. J. Lowry. 1981. Iodination of proteins, glycoproteins, and peptides using a solid-phase oxidizing agent, 1,3,4,6-tetrachloro-3 alpha, 6 alpha-diphenyl glycoluril (lodogen). Anal. Biochem. 117: 136-146.
32. Young, S. C., J. L. Witztum, D. C. Casal, L. K. Curtiss, and S. Bernstein. 1986. Conservation of the low density lipoprotein-receptor domain of apoprotein B demonstrated by new monoclonal antibody, MB47. Arteriosclerosis. 6: 178-188.
33. Hill, J. S., and P. H. Pritchard. 1990. Improved phenotyping of apolipoprotein E: application to population frequency distribution. Clin. Chem. 36: 1871-1874.
34. Francone, O. L., A. Gurakar, and C. Fielding. 1989. Distribution and functions of lecithin : cholesterol acyltransferase and cholesteryl ester transfer protein in plasma lipoproteins. Evidence for a functional unit containing these activities together with apolipoproteins A-I and D that catalyzes the esterification and transfer of cell-derived cholesterol. J. Biol. Chem. 264: 7066-7072.
35. von Eckardstein, A., Y. Huang, S. Wu, H. Funke, G. Noseda, and G. Assmann. 1995. Reverse cholesterol transport in plasma of patients with different forms of familial HDL deficiency. Arterioscler. Thromb. Vasc. Biol. 15: 691-703.
36. Castro, G. R., and C. J. Fielding. 1984. Evidence for the distribution of apolipoprotein E between lipoprotein classes in human normocholesterolemic plasma and for the origin of unassociated apolipoprotein E (Lp-E). J. Lipid Res. 25: 58-67.
37. Miida, T., M. Kawano, C. J. Fielding, and P. E. Fielding. 1992. Regulation of the concentration of preβ high-density lipoprotein in normal plasma by cell membranes and lecithin-cholesterol acyltransferase activity. Biochemistry. 31: 11112-11117.
38. Francone, O. L., C. J. Fielding, and P. E. Fielding. 1990. Distribution of cell-derived cholesterol among plasma lipoproteins: a comparison of three techniques. J. Lipid Res. 31: 2195-2200.
39. Davidson, W. S., D. L. Sparks, S. Lund-Katz, and M. C. Phillips, 1994. The molecular basis for the difference in charge between pre-β-and α-migrating high density lipoproteins. J. Biol. Chem. 269: 8959-8965.
40. Lund-Katz, S., K. H. Weisgraber, R. W. Mahley, and M. C. Phillips. 1993. Conformation of apolipoprotein E in lipoproteins. J. Biol. Chem. 268: 23008-23015.
41. Fielding, C. J., G. R. Castro, C. Donner, P. E. Fielding, and G. M. Reaven. 1986. Distribution of apolipoprotein E in the plasma of insulin-dependent and non-insulin-dependent diabetics and its relation to cholesterol net transport. J. Lipid Res. 27: 1052-1061.
42. Fielding, C. J., J. Frohlich, K. Moser, and P. E. Fielding. 1982. Promotion of sterol efflux and net transport by apolipoprotein E in lecithin:cholesterol acyltransferase deficiency. Metabolism. 31: 1023-1028.
43. Mahley, R. W., T. L. Innerarity, K. H. Weisgraber, and D. L. Fry. 1977. Canine hyperlipoproteinemia and atherosclerosis. Accumulation of lipid by aortic medial cells in vivo and in vitro. Am. J. Pathol. 87: 205-225.
44. Gibson, J. C., and W. V. Brown. 1988. Effect of lipoprotein lipase and hepatic triglyceride lipase activity on the distribution of apolipoprotein E among the plasma lipoproteins. Atherosclerosis. 75: 45-55.
45. Mahley, R. W., T. L. Innerarity, and K. H. Weisgraber. 1980. Alterations in metabolic activity of plasma lipoproteins following selective chemical modification of the apoproteins. Ann. NY Acad. Sci. 348: 265-277.
46. Thuren, T., R. W. Wilcox, P. Sisson, and M. Waite. 1991. Hepatic lipase hydrolysis of lipid monolayers. Regulation by apolipoproteins. J. Biol. Chem. 266: 4853-4861.
47. Evans, G. F., W. R. Bensch, L. D. Apelgren, D. Bailey, R. F. Kauffman, T. F. Bumol, and S. H. Zuckerman. 1994. Inhibition of cholesteryl ester transfer protein in normocholesterolemic and hypercholesterolemic hamsters: effect on HDL subspecies, quantity, and apolipoprotein distribution. J. Lipid Res. 35: 1634-1645.
48. Marcel, Y. L., C. Vézina, D. Emond, R. B. Verdery, and R. W. Milne. 1981. High density lipoprotein subfractions isolated by heparin-Sepharose affinity chromatography and their role in cholesteryl ester transfer to very low density lipoproteins. J. Lipid Res. 22: 1198-1205.
49. Marcel, Y. L., C. Vézina and R. W. Milne. 1983. Cholesteryl ester and apolipoprotein E transfer between human high density lipoproteins and chylomicrons. Biochim. Biophys. Acta. 750: 411-417.
50. Saxena, U., E. Ferguson, and C. L. Bisgaier. 1993. Apolipoprotein E modulates low density lipoprotein retention by lipoprotein lipase anchored to the subendothelial matrix. J. Biol. Chem. 268: 14812-14819.
51. Wilson, H. M., J. C. Patel, D. Russell, and E. R. Skinner. 1993. Alterations in the concentration of an apolipoprotein E-containing subfraction of plasma high density lipoprotein in coronary heart disease. Clin. Chim. Acta. 220: 175-187.