Differences in nucleotide specificity and catalytic mechanism between Vibrio harveyi aldehyde dehydrogenase and other members of the aldehyde dehydrogenase superfamily

Chemico-Biological Interactions

Volumn 130-132, Issue , 2001, Pages 29-38

  Zhang, Lei ^a   Ahvazi, Bijan ^a   Szittner, Rose ^a   Vrielink, Alice ^a   Meighen, Edward ^a  

^a MCGILL UNIVERSITY   (Canada)

Author keywords

General base; NADP+ specificity; V. harveyi ALDH

Indexed keywords

ALDEHYDE DEHYDROGENASE; ARGININE; ASPARAGINE; CYSTEINE; GLUTAMIC ACID; HISTIDINE; NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; THREONINE;

BINDING AFFINITY; CATALYSIS; CONFERENCE PAPER; ENZYME BINDING; ENZYME ISOLATION; ENZYME MECHANISM; ENZYME SPECIFICITY; ENZYME SUBSTRATE; NONHUMAN; VIBRIO HARVEYI;

ALDEHYDE DEHYDROGENASE; CATALYTIC DOMAIN; HYDROGEN BONDING; KINETICS; MODELS, MOLECULAR; NADP; POINT MUTATION; PROTEIN CONFORMATION; SUBSTRATE SPECIFICITY; VIBRIO;

BACTERIA (MICROORGANISMS); VIBRIO HARVEYI;

EID: 0035969892     PISSN: 00092797     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0009-2797(00)00219-2     Document Type: Conference Paper

References (15)

1. + (+)- specific fatty aldehyde dehydrogenase from Vibrio harveyi
2. Vibrio harveyi aldehyde dehydrogenase. Partial reversal of aldehyde oxidation and its possible role in the reduction of fatty acids for the bioluminescence reaction
3. + dependent aldehyde dehydrogenase from Vibrio harveyi. Structural implications for cofactor specificity and affinity
4. The first structure of an aldehyde dehydrogenase reveals novel interactions between NAD and the Rossmann fold
5. Structure of mitochondrial aldehyde dehydrogenase: The genetic component of ethanol aversion
6. Structure of betaine aldehyde dehydrogenase at 2.1 A resolution
7. Sheep liver cytosolic aldehyde dehydrogenase: The structure reveals the basis for the retinal specificity of class 1 aldehyde dehydrogenases
8. The structure of retinal dehydrogenase type II at 2.7 A resolution: Implications for retinal specificity
9. +-dependent aldehyde dehydrogenase from Streptococcus mutans
10. Change of nucleotide specificity and enhancement of catalytic efficiency in single point mutants of Vibrio harveyi aldehyde dehydrogenase
11. Relationships within the aldehyde dehydrogenase extended family
12. Aldehyde dehydrogenase catalytic mechanism. A Proposal
13. Three-dimensional structure of mitochondrial aldehyde dehydrogenase. Mechanistic implications
14. Involvement of glutamate 268 in the active site of human liver mitochondrial (class 2) aldehyde dehydrogenase as probed by site- directed mutagenesis
15. Differences in the roles of conserved glutamic acid residues in the active site of human class 3 and class 2 aldehyde dehydrogenases