Change of nucleotide specificity and enhancement of catalytic efficiency in single point mutants of Vibrio harveyi aldehyde dehydrogenase

Biochemistry

Volumn 38, Issue 35, 1999, Pages 11440-11447

  Zhang, Lei ^a   Ahvazi, Bijan ^a   Szittner, Rose ^a   Vrielink, Alice ^a   Meighen, Edward ^a  

^a MCGILL UNIVERSITY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ALDEHYDE DEHYDROGENASE; NICOTINAMIDE ADENINE DINUCLEOTIDE; NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE;

ARTICLE; CONFORMATIONAL TRANSITION; ENZYME CONFORMATION; ENZYME INACTIVATION; ENZYME ISOLATION; HYDROGEN BOND; MOLECULAR INTERACTION; NONHUMAN; NUCLEOTIDE SEQUENCE; POINT MUTATION; PRIORITY JOURNAL; STRUCTURE ACTIVITY RELATION; VIBRIO HARVEYI;

ADENINE NUCLEOTIDES; ADENOSINE DIPHOSPHATE; ADENOSINE MONOPHOSPHATE; ALDEHYDE DEHYDROGENASE; AMINO ACID SEQUENCE; CATALYSIS; ENZYME ACTIVATION; ENZYME INHIBITORS; ENZYME STABILITY; HEAT; HYDROGEN-ION CONCENTRATION; KINETICS; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; NAD; NADP; NICOTINAMIDE MONONUCLEOTIDE; POINT MUTATION; SUBSTRATE SPECIFICITY; VIBRIO;

BACTERIA (MICROORGANISMS); FELIS CATUS; VIBRIO HARVEYI;

EID: 0033621096     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi991101g     Document Type: Article

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