Differences in the roles of conserved glutamic acid residues in the active site of human class 3 and class 2 aldehyde dehydrogenases

Protein Science

Volumn 8, Issue 10, 1999, Pages 1922-1929

  Mann, Craig J ^a   Weiner, Henry ^a  

^a PURDUE UNIVERSITY   (United States)

Author keywords

Aldehyde dehydrogenase; Catalytic residues; NAD(H) conformation; Rate limiting step; Site directed mutagenesis

Indexed keywords

ALDEHYDE DEHYDROGENASE; ESTERASE; GLUTAMIC ACID; GLUTAMINE; ISOENZYME; MITOCHONDRIAL ENZYME; NICOTINAMIDE ADENINE DINUCLEOTIDE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE;

AMINO ACID SEQUENCE; ARTICLE; CONTROLLED STUDY; DEACYLATION; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME BINDING; ENZYME STRUCTURE; HUMAN; LIVER MITOCHONDRION; NONHUMAN; PRIORITY JOURNAL; RAT; STRUCTURE ACTIVITY RELATION;

EID: 0032872782     PISSN: 09618368     EISSN: None     Source Type: Journal    
DOI: 10.1110/ps.8.10.1922     Document Type: Article

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