Aldehyde dehydrogenase catalytic mechanism: A proposal

Advances in Experimental Medicine and Biology

Volumn 463, Issue , 1999, Pages 53-59

  Hempel, J ^a   Perozich, J ^a   Chapman, T ^a   Rose, J ^a   Boesch, J S ^a   Liu, Z J ^a   Lindahl, R ^a   Wang, B C ^a  

^a UNIVERSITY OF PITTSBURGH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALDEHYDE DEHYDROGENASE; APOENZYME; BENZALDEHYDE; GLUTAMIC ACID; NICOTINAMIDE ADENINE DINUCLEOTIDE;

AMINO ACID SEQUENCE; AMINO TERMINAL SEQUENCE; CATALYSIS; CONFERENCE PAPER; CRYSTAL STRUCTURE; CRYSTALLOGRAPHY; ENZYME CONFORMATION; ENZYME KINETICS; ENZYME MECHANISM; ENZYME STRUCTURE; PRIORITY JOURNAL; PROTEIN QUATERNARY STRUCTURE; SITE DIRECTED MUTAGENESIS;

EID: 0033282375     PISSN: 00652598     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-1-4615-4735-8_7     Document Type: Conference Paper

References (16)

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4. Hydride transfer stereospecificity of rat liver aldehyde dehydrogenases
5. CoA- dependent methylmalonate-semialdehyde dehydrogenase, a unique member of the aldehyde dehydrogenase superfamily
6. The inactivation of aldehyde dehydrogenase by disulfiram in the presence of glutathione
7. Crystal structure of a class 3 aldehyde dehydrogenase at 2.6,Å resolution
8. The first structure of an aldehyde dehydrogenase reveals novel interactions between NAD and the Rossmann fold
9. Structure of a class I mammalian aldehyde dehydrogenase at 2.35Å resolution
10. Involvement of Glutamate 399 and Lysine 192 in the mechanism of human liver mitochondrial aldehyde dehydrogenase
11. The aldehyde dehydrogenase extended family: An overview
12. Relationships within the aldehyde dehydrogenase extended family
13. Preliminary crystallographic analysis of class 3 rat liver aldehyde dehydrogenase
14. Structure of mitochondrial aldehyde dehydrogenase: The genetic component of ethanol aversion
15. Critical glutamic acid residiues affecting the mechanism and nucleotide specificity of Vibrio harveyi aldehyde dehydrogenase
16. Involvement of Glutamate 268 in the acitive site of human liver mitochondrial aldehyde dehydrogenase as probed by site-directed mutagenesis