Beyond the catalytic core of ALDH: A web of important residues begins to emerge

Chemico-Biological Interactions

Volumn 130-132, Issue , 2001, Pages 39-46

  Hempel, John ^a   Lindahl, Ronald ^b   Perozich, John ^a   Wang, Bi Cheng ^c   Kuo, Ingrid ^a   Nicholas, Hugh ^d  

^a UNIVERSITY OF PITTSBURGH   (United States)

^b UNIVERSITY OF SOUTH DAKOTA   (United States)

^c University of Georgia ^*  (United States)

^d CARNEGIE MELLON UNIVERSITY   (United States)

Author keywords

Aldehyde dehydrogenase; Aspartic acid; Catalytic center; Folding; Glutamic acid; Phenylalanine; Proline; Second tier residues; Site directed mutagenesis

Indexed keywords

ALDEHYDE DEHYDROGENASE; ASPARTIC ACID; GLUTAMIC ACID; MUTANT PROTEIN; PHENYLALANINE; PROLINE;

AMINO ACID SUBSTITUTION; CATALYSIS; CONFERENCE PAPER; ENZYME ANALYSIS; ENZYME KINETICS; ENZYME STRUCTURE; NONHUMAN; PROTEIN FOLDING; SITE DIRECTED MUTAGENESIS;

ALDEHYDE DEHYDROGENASE; AMINO ACID MOTIFS; ANIMALS; CATALYTIC DOMAIN; HUMANS; KINETICS; MODELS, MOLECULAR; MUTAGENESIS, SITE-DIRECTED; PROTEIN FOLDING; RATS; RECOMBINANT PROTEINS;

EID: 0035969885     PISSN: 00092797     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0009-2797(00)00220-9     Document Type: Conference Paper

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