Intracellular chelation of iron by bipyridyl inhibits DNA virus replication: Ribonucleotide reductase maturation as a probe of intracellular iron pools

Journal of Biological Chemistry

Volumn 276, Issue 26, 2001, Pages 24301-24308

  Romeo, Annette M ^b   Christen, Linda ^b   Niles, Edward G ^b   Kosman, Daniel J ^a  

^a UNIVERSITY AT BUFFALO   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

BIOSYNTHESIS; CELLS; DNA; RNA; VIRUSES;

INTRACELLULAR CHELATION;

BIOCHEMISTRY;

2,2' BIPYRIDINE; BIPYRIDINE; CYCLOHEXIMIDE; CYTARABINE; HYDROXYUREA; IRON; IRON REGULATORY FACTOR; RIBONUCLEOTIDE REDUCTASE; VIRUS PROTEIN; DYES, REAGENTS, INDICATORS, MARKERS AND BUFFERS; IRON CHELATING AGENT; IRON REGULATORY PROTEIN 1; IRON SULFUR PROTEIN; RNA BINDING PROTEIN;

ANIMAL CELL; ARTICLE; CHELATION; CONTROLLED STUDY; DNA SYNTHESIS; DNA SYNTHESIS INHIBITION; ENZYME ACTIVITY; HERPES SIMPLEX VIRUS 1; IRON CHELATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN SYNTHESIS; RNA BINDING; VACCINIA VIRUS; VESICULAR STOMATITIS VIRUS; VIRUS INFECTION; VIRUS INHIBITION; VIRUS REPLICATION; ANIMAL; CELL LINE; CYTOPLASM; DRUG EFFECT; ENZYMOLOGY; GENETICS; GROWTH, DEVELOPMENT AND AGING; METABOLISM; VIRUS CULTURE;

ANIMALIA; DNA VIRUSES; HUMAN HERPESVIRUS 1; MAMMALIA; SIMPLEXVIRUS; VACCINIA VIRUS; VESICULAR STOMATITIS VIRUS;

2,2'-DIPYRIDYL; ANIMALS; CELL LINE; CYTOPLASM; HERPESVIRUS 1, HUMAN; INDICATORS AND REAGENTS; IRON; IRON CHELATING AGENTS; IRON REGULATORY PROTEIN 1; IRON-REGULATORY PROTEINS; IRON-SULFUR PROTEINS; PLAQUE ASSAY; RIBONUCLEOTIDE REDUCTASES; RNA-BINDING PROTEINS; VACCINIA VIRUS; VESICULAR STOMATITIS-INDIANA VIRUS; VIRAL PROTEINS; VIRUS REPLICATION;

EID: 0035968195     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M010806200     Document Type: Article

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