Microsomal Triglyceride Transfer Protein Binding and Lipid Transfer Activities Are Independent of Each Other, but Both are Required for Secretion of Apolipoprotein B Lipoproteins from Liver Cells

Journal of Biological Chemistry

Volumn 276, Issue 30, 2001, Pages 28606-28612

  Liang, Jun Shan ^a   Ginsberg, Henry N ^a  

^a NONE

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL ORGANS; CELLS; DNA; LIPIDS; POLYPEPTIDES; PROTEINS;

BINDING SITES;

BIOCHEMISTRY;

AMINO ACID; APOLIPOPROTEIN B; APOLIPOPROTEIN B100; APOLIPOPROTEIN B13; APOLIPOPROTEIN B16BETA; APOLIPOPROTEIN B34; APOLIPOPROTEIN B42; CHAPERONE; COMPLEMENTARY DNA; LIPID; LIPOPROTEIN; MICROSOMAL TRIGLYCERIDE TRANSFER PROTEIN; POLYPEPTIDE; PROTEASOME; UNCLASSIFIED DRUG; PEPTIDE; TRIACYLGLYCEROL;

AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; BETA SHEET; BINDING AFFINITY; BINDING SITE; CELL STRAIN HEPG2; CONTROLLED STUDY; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; LIPID TRANSPORT; LIVER CELL; NONHUMAN; PEPTIDE SYNTHESIS; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN LIPID INTERACTION; PROTEIN PROTEIN INTERACTION; PROTEIN SECRETION; ANIMAL; CHEMISTRY; CHO CELL; GENE DELETION; HAMSTER; LIPID METABOLISM; LIVER; LIVER MICROSOME; METABOLISM; PROTEIN BINDING; PROTEIN SECONDARY STRUCTURE; PROTEIN TERTIARY STRUCTURE; SECRETION; SERODIAGNOSIS;

ANIMALIA;

ANIMALS; APOLIPOPROTEINS B; CHO CELLS; CRICETINAE; DNA, COMPLEMENTARY; GENE DELETION; HUMANS; LIPID METABOLISM; LIVER; MICROSOMES, LIVER; PEPTIDES; PRECIPITIN TESTS; PROTEIN BINDING; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; TRANSFECTION; TRIGLYCERIDES;

EID: 0035958947     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M100294200     Document Type: Article

References (37)

1. Wetterau, J. R., and Zilversmit, D. B. (1985) Chem. Phys. Lipids 38, 205-222
2. Wetterau, J. R., and Zilversmit, D. B. (1986) Biochim. Biophys. Acta 875, 610-617
3. Wetterau, J. R., Combs, K. A., McLean, L. R., Spinner, S. N., and Aggerbeck, L. P. (1991) Biochemistry 30, 9728-9735
4. Gordon, D. A., Jamil, H., Sharp, D., Mullaney, D., Yao, Z., Gregg, R. E., and Wetterau, J. (1994) Proc. Natl. Acad. Sci. U. S. A. 91, 7628-7632
5. Leiper, J. M., Bayliss, J. D., Pease, R. J., Brett, D. J., Scott, J., and Shoulders, C. C. (1994) J. Biol. Chem. 269, 21951-21954
6. Gretch, D. G., Sturley, S. L., Wang, L., Lipton, B. A., Dunning, A., Grunwald, K. A. A., Wetterau, J. R., Yao, Z., Talmud, P., and Attie, A. D. (1996) J. Biol. Chem. 271, 8682-8691
7. Gordon, D. A., Wetterau, J. R., and Gregg, R. E. (1995) Trends Cell Biol. 5, 317-321
8. Benoist F, and Grand-Perret, T. (1997) J. Biol. Chem. 272, 20435-20442
9. Wang, S, McLeod, R. S., Gordon, D. A., and Yao, Z. (1996) J. Biol. Chem. 271, 14124-14133
10. Jamil, H., Gordon, D. A., Eustice, D. C., Brooks, C. M., Dickson, J. K., Jr, Chen, Y., Ricci, B., Chu, C. H., Harrity, T. W., Ciosek, C. P., Jr, Biller, S. A., Gregg, R. E., and Wetterau, J. R. (1996) Proc. Natl. Acad. Sci. U. S. A. 93, 11991-11995
11. Gordon, D. A., Jamil, H., Gregg, R. E., Olofsson, S. O., and Boren, J. (1996) J. Biol. Chem. 271, 33047-33053
12. Zhou, M., Fisher, E. A., and Ginsberg, H. N. (1998) J. Biol. Chem. 273, 24649-24653
13. Raabe, M., Flynn, L. M., Zlot, C. H., Wong, J. S., Veniant, M. M., Hamilton, R. L., and Young, S. G. (1998) Proc. Natl. Acad. Sci. U. S. A. 95, 8686-8691
14. Chang, B. H., Liao, W., Li, L., Nakamuta, M., Mack, D., and Chan, L. (1999) J. Biol. Chem. 274, 6051-6055
15. Tietge, U. J., Bakillah, A., Maugeais, C., Tsukamoto, K., Hussain, M., and Rader, D. J. (1999) J. Lipid Res. 40, 2134-2139
16. Taghibiglou, C., Carpentier, A., Van Iderstine, S. C., Chen, B., Rudy, D., Aiton, A., Lewis, G. F., and Adeli, K. (2000) J. Biol. Chem. 275, 8416-8425
17. Segrest, J. P., Jones, M. K., Mishra, V. K., Anantharamaiah, G. M., and Garber, D. W. (1994) Arterioscler. Thromb. 14, 1674-1685
18. Swift, L. L. (1995) J. Lipid Res. 36, 395-406
19. Boren, J., Rustaeus, S., and Olofsson, S. O. (1994) J. Biol. Chem. 269, 25879-25888
20. Mc Leod, R. S., Wang, Y., Wang, S., Rusinol, A., Links, P., and Yao, Z. (1996) J. Biol. Chem. 271, 18445-18455
21. Liang, J. S., Wu, X. U., Jiang, H. S., Zhou, M. Y., Yang, H. Y., Angkeow, P., Huang, L. S., Sturley, S. L., and Ginsberg, H. N. (1998) J. Biol. Chem. 273, 35216-35221
22. Wu, X., Zhou, M., Huang, L. S., Wetterau, J., and Ginsberg, H. N. (1996) J. Biol. Chem. 271, 10277-10281
23. Patel, S. B., and Grundy, S. M. (1996) J. Biol. Chem. 271, 18686-18694
24. Hussain, M. M., Bakillah, A., Nayak, N., and Shelness, G. S. (1998) J. Biol. Chem. 273, 25612-25615
25. Bakillah, A., Jamil, H., and Hussain, M. M. (1998) Biochemistry 37, 3727-3734
26. Mann, C. J., Anderson, T. A., Read, J., Chester, S. A., Harrison, G. B., Köchl, S., Ritchie, P. J., Bradbury, P., Hussain, F. S., Amey, J., Vanloo, B., Rosseneu, M., Infante, R., Hancock, J. M., Levitt, D. G., Banaszak, L. J., Scott, J., and Shoulders, C. C. (1999) J. Mol. Biol. 285, 391-408
27. Bradbury, P., Mann, C. J., Köchl, S., Anderson, T. A., Chester, S. A., Hancock, J. M., Ritchie, P. J., Amey, J., Harrison, G. B., Levitt, D. G., Banaszak, L. J., Scott, J., and Shoulders, C. C. (1999) J. Biol. Chem. 274, 3159-3164
28. Haghpassand, M., Wilder, D., and Moberly, J. B. (1996) J. Lipid Res. 37, 1468-1480
29. Dixon, J. L., and Ginsberg, H. N. (1993) J. Lipid Res. 34, 167-179
30. Heinemann, T., Metzger, S., Fisher, E. A., Breslow, J. L., and Huang, L.-S. (1994) J. Lipid Res. 35, 2200-2211
31. Huang, X. F., and Shelness, G. S. (1997) J. Biol. Chem. 272, 31872-31876
32. Tran, K., Boren, J., Macri, J., Wang, Y., McLeod, R., Avramoglu, R. K., Adeli, K., and Yao, Z. (1998) J. Biol. Chem. 273, 7244-7251
33. Mitchell, D. M., Zhou, M., Pariyarath, R., Wang, H., Aitchison, J. D., Ginsberg, H. N., and Fisher, E. A. (1998) Proc. Natl. Acad. Sci. U. S. A. 95, 14733-14738
34. Fisher, E. A., Zhou, M., Mitchell, D. M., Wu, X., Omura, S., Wang, H., Goldberg, A. L., and Ginsberg, H. N. (1997) J. Biol. Chem. 272, 20427-20434
35. Davis, R. A. (1999) Biochim. Biophys. Acta 1440, 1-31
36. Wetteau, J. R., Aggerbeck, L. P., Bouma, M. E., Eisenberg, C., Munk, A., Hermier, M., Schmitz, J., Rader, D. J., and Gregg, R. E. (1992) Science 258, 999-1001
37. Bakillah, A., Nayak, N., Saxena, U., Medford, R. M., and Hussain, M. M. (2000) Biochemistry 39, 4892-4899