The development of Cop 1 (Copaxone®), an innovative drug for the treatment of multiple sclerosis: Personal reflections

Immunology Letters

Volumn 50, Issue 1-2, 1996, Pages 1-15

  Arnon, Ruth ^a  

^a WEIZMANN INSTITUTE OF SCIENCE   (Israel)

Author keywords

Copaxone ; Immunospecific drug; Multiple sclerosis

Indexed keywords

GLATIRAMER;

ALLERGIC ENCEPHALOMYELITIS; CLINICAL TRIAL; GUINEA PIG; HUMAN; MAJOR HISTOCOMPATIBILITY COMPLEX; MULTIPLE SCLEROSIS; NONHUMAN; PHASE 3 CLINICAL TRIAL; PRIORITY JOURNAL; REVIEW; SUPPRESSOR CELL;

EID: 0030013545     PISSN: 01652478     EISSN: None     Source Type: Journal    
DOI: 10.1016/0165-2478(96)02506-0     Document Type: Short Survey

References (67)

1. Sela, M. (1969) Science 166, 1365-1374.
2. Arnon, R., Sela, M., Rachaman, E.S. and Shapiro, D. (1967) Eur. J. Biochem. 2, 80-83.
3. Teitelbaum, D., Arnon, R., Sela, M., Rabinsohn, Y. and Shapiro, D. (1973) Immunochemistry 10, 735-743.
4. Arnon, R., Crisp, E., Kelley, R., Ellison, G.W., Meyers, L.W. and Tourtellote, W.W. (1980) J. Neurol. Sci. 46, 179-186.
5. Rivers, T.M. and Schwenker., F.F. (1937) J. Exp. Med. 61, 689-702.
6. Bernard, C.C., Ledon, J. and Mackay, I.R. (1976) Eur. J. Immunol. 6, 655-660.
7. Ortiz-Ortiz, L. and Weigle, W.O. (1976) J. Exp. Med. 144, 604-616.
8. Paterson., P.Y. (1966) Adv. Immunol. 5, 131-208.
9. Shaw, C-M., Alvord, E.C., Fahlberg., W.J and Kies, M.W. (1962) J. Immunol. 89, 54-61.
10. Einstein, E.R., Chao, L.P. and Csejtey, J. (1972) Immunochemistry 9, 1013-1019.
11. Swanborg, R.H. (1974) J. Immunol. 114, 191-194.
12. Teitelbaum, D., Meshorer, A., Hirshfeld, T., Arnon, R. and Sela, M. (1971) Eur. J. Immunol. 1, 242-298.
13. Hirshfeld, H., Teitelbaum, D., Arnon, R. and Sela, M. (1970) FEBS Lett. 7, 317-320.
14. Webb, C., Teitelbaum, D., Arnon, R. and Sela, M. (1973) Eur. J. Immunol. 3, 279-286.
15. Teitelbaum, D., Aharoni, R., Sela, M. and Arnon, R. (1991) Proc. Natl. Acad. Sci. USA 88, 9528-9532.
16. Roboz-Einstein, E., Chao, L.-P., Csejtey, J. Kibler, R.F. and Shapira, R. (1972) Immunochemistry 91, 73-84.
17. Teitelbaum, D., Webb, C., Meshorer, A., Arnon, R. and Sela, M. (1973) Eur. J. Immunol. 3, 273-279.
18. Webb, C., Teitelbaum, D., Herz, A., Arnon, R. and Sela, M. (1976) Immunochemistry. 13, 333-332.
19. Lando, Z., Teitelbaum, D. and Arnon, R. (1979) Israel J. Med. Sci. 15, 868.
20. Teitelbaum, D., Webb, C., Bree, M., Meshorer, A., Arnon. R. and Sela, M. (1974) J. Clin. Immunol. Immunopathol. 3, 256-262.
21. Teitelbaum, D., Meshorer A., and Arnon, R. (1977) Israel Med. Sci. 13, 1038 (abstract).
22. Wisniewski, H.M. and Keith, A.B. (1977) Ann. Neurol. 1, 144-148.
23. Keith, A.B., Arnon, R., Teitelbaum, D., Caspary, A. and Wisniewski, H.M. (1979) J. Neurol. Sci. 42, 267-274.
24. Abramsky, O., Teitelbaum, D. and Arnon, R. (1977) J. Neurol. Sci. 31, 433-438.
25. Bornstein, M.B. (1963) Natl. Cancer Inst. Monogr. 11, 197-214.
26. Bornstein, M.B. and Johnson, K.P. (1992) in: Treatment of Multiple Sclerosis. (A. Rudick and D.E. Goodkin, Eds.) pp. 173-198. Springer Verlag, Heidelberg.
27. Bornstein, M.B., Miller, A.L., Teitelbaum, D., Arnon, R. and Sela, M. (1982) Ann. Neurol. 11, 317-319.
28. Bornstein, M., Miller, A., Slagle, S., Weitzman, M., Crystal, H., Drexler, E., Keilson, M., Merriam, A., Wassertheil-Smoller, S., Spada, V., Arnon, R., Jacobsohn, I., Teitelbaum, T., and Sela, M. (1987) New Engl. J. Med. 317, 408-414.
29. Bornstein, M.B., Miller, A., Slagle, S., Weitzman, M., Crystal, H., Drexler, E., Keilson, M., Merriam, A., Wassertheil-Smoller, S., Spada, V., Weiss, W., Arnon, R., Jacobsohn, I., Teitelbaum, D. and Sela, M. (1988) Neurology. 38 (Suppl. 2), 66-69.
30. Bornstein, M.B., Slagle, S., Weitzman, M.B., Crystal, H., Merriam, A.E., Wassertheil-Smoller, S., Spada, V., Weiss, W., Miller, A.E., Drexler, E., Keilson, M., Appel, S.H., Rolak, L., Arnon, R., Sela, M., Jacobsohn, I. and Teitelbaum, D. (1990) in: Handbook of Multiple Sclerosis (S.B. Cook, ed.) pp. 469-480. Marcel Dekker Inc. NY.
31. Abramsky, O., Teitelbaum, D. and Arnon, R. (1977) Eur. J. Immunol. 7, 213-217.
32. Abramsky, O., Teitelbaum, D., Webb, C. and Arnon, R. (1975) J. Neuropathol. Exp. Neurol. 34, 36-45.
33. Abramsky, O., Webb, C., Teitelbaum, D. and Arnon, R. (1975) Neurology 25, 1154-1159.
34. Abramsky, O., Webb, C., Teitelbaum, D. and Arnon, R. (1975) J. Neurol. Sci. 26, 13-20.
35. Tiwari, J.L. and Terasaki, P.I. (1985) In: Multiple sclerosis in HLA and disease association. (J.E. Tiwari and P.I. Terasaki, eds.) pp. 152-167. Springer-Verlag, New York.
36. Stone, S.H., Lerner E.M., and Goode, J.H. Jr. (1969) Proc. Soc. Exp. Biol. Med. 132, 341-344.
37. Webb, C., Teitelbaum, D., Arnon, R. and Sela, M. (1973) Immunol. Commun. 2, 185-192.
38. Teitelbaum, D., Webb, C., Arnon, R., and Sela, M. (1977) Cell. Immunol. 29, 265-271.
39. Teitelbaum D. and Arnon, R. (1981) J. Immunogenet. 8, 107-112.
40. Lando, Z., Teitelbaum, D. and Arnon, R. (1979) Immunogenetics 9, 435-442.
41. Lando, Z., Teitelbaum, D. and Arnon, R. (1979) J. Immunol. 123, 2156-2160.
42. Swierkosz, J.E. and Swanborg, R.H. (1975) J. Immunol. 115, 631-633.
43. Bernard, C.C.A. (1977) Clin. Exp. Immunol. 29, 100-109.
44. Lando, Z., Teitelbaum, D. and Arnon, R. (1980) Nature 287, 551-552.
45. Aharoni, R., Teitelbaum, D. and Arnon, R. (1993) Eur. J. Immunol. 23, 17-25.
46. Lando, Z., Dori, Y., Teitelbaum, D. and Arnon, R. (1981) J. Immunol. 127, 1915-1919.
47. Lando, Z., Teitelbaum, D. and Arnon, R. (1981) J. Immunol. 126, 1526-1528.
48. Lando, Z, Dori, Y., Teitelbaum, D. and Arnon, R. (1982) J. Neurol. Sci. 53, 113-123.
49. Bornstein, M.B., Miller, A., Slagle, S., Weitzman, M., Drexler, E., Keilson, M., Spada, V., Weiss, W., Appel, S., Rolak, L., Harati, Y., Brown, S., Arnon, R. Jacobsohn, I., Teitelbaum, D. and Sela, M. (1991) Neurology 41, 533-539.
50. Zinkernagel, R. (1993) Int. Arch. Allergy Immunol. 100, 8-11.
51. Arnon, R., Teitelbaum, D. (1993) Int. Arch. Allergy Immunol. 100, 2-7.
52. Webb, C., Teitelbaum, D., Abramsky, O., Arnon, R. and Sela, M. (1974) Lancet ii, 66-68.
53. Teitelbaum, D., Aharoni, R., Arnon, R. and Sela, M. (1988) Proc. Natl. Acad. Sci. USA 85, 9724-9728.
54. Teitelbaum, D., Milo, R., Arnon, R. and Sela, M. (1992) Proc. Natl. Acad. Sci. USA 89, 137-141.
55. Mozes, E., Dayan, M., Zisman, E., Brocke, S., Licht, A. and Pecht, I. (1989) EMBO J. 8 4049-4052
56. Fridkis-Hareli, M., Teitelbaum, D., Gurevich, E., Pecht, I., Brautbar, C., Oh Joong, K., Brenner, T., Arnon, R. and Sela, M. (1994) Proc. Natl. Acad. Sci. USA 91, 4872-4876.
57. Fridkis-Hareli, M., Teitelbaum, D., Arnon, R. and Sela, M. (1995) Cell. Immunol. 163, 229-236.
58. Fridkis-Hareli, M., Teitelbaum, D., Kerlero de Rosbo, N., Arnon, R. and Sela, M. (1994) J. Neurochem. 63 (Suppl. 1), 561.
59. Kerlero de Rosbo, N., Mendel, I. and Ben-Nun, A. (1995) Eur. J. Immunol. 25, 985-993.
60. Tuohy, V. K., Lu, Z., Sobel, R.A., Laursen, R.A. and Lees, M.B. (1989) J. Immunol. 142, 1523-1527.
61. Greer, J. M., Kuchroo., V.K., Sobel, R.A. and Lees, M.B. (1992) J. Immunol. 149, 783-788.
62. Teitelbaum, D., Fridkis-Hareli, M. Arnon, R. and Sela, M. (1995) J. Neuroimmunol., in press.
63. Ben-Nun, A., Mendel, I., Bakimer, R., Fridkis-Hareli, M., Teitelbaum, T., Arnon, R., Sela, M. and Kerlero de Rosbo, N. (1995) J. Neurol., in press.
64. Arnon, R., Sela, M. and Teitelbaum, D. (1995) Neurol. Suppl., in press.
65. K.P. Johnson, Brooks, B.R., Cohen, J.A., Ford, C.C., Goldstein, J., Lisak, R.P., Myers, L.W., Panitech, H.S., Rose, J.W., Schiffer, R.B., Vollmer, T., Weiner, L.P. and Wollinsky, J.S. (1995) Neurology 45, 1268-1276.
66. Arnon, R. and Teitelbaum, D. (1994) Ther. Immunol. 1, 65-70.
67. Aharoni, R., Teitelbaum, D., Arnon, R. and Puri, J. (1991) Nature 351, 147-150.