Cyclin D1 as a proliferative marker regulating retinoblastoma phosphorylation in mouse lung epithelial cells

Cancer Letters

Volumn 168, Issue 2, 2001, Pages 165-172

  Mamay, Cynthia L ^a   Schauer, Irene E ^a   Rice, Pamela L ^a   Dwyer Nield, Lori D ^a   You, Ming ^b   Sclafani, Robert A ^a   Malkinson, Alvin M ^a  

^a UNIVERSITY OF COLORADO CANCER CENTER   (United States)

^b MEDICAL COLLEGE OF OHIO   (United States)

Author keywords

Cyclin D1; Mouse lung epithelial cells; Proliferative marker; Retinoblastoma phosphorylation

Indexed keywords

BUTYLCRESOL; CYCLIN D1; RETINOBLASTOMA PROTEIN; TUMOR EXTRACT;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER CELL CULTURE; CELL PROLIFERATION; EPITHELIUM CELL; GROWTH INHIBITION; HYPERPLASIA; LUNG ALVEOLUS EPITHELIUM; LUNG TUMOR; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN CONTENT; PROTEIN PHOSPHORYLATION; TUMOR CELL;

ANIMALS; BIOLOGICAL MARKERS; CELL DIVISION; CELL LINE; CYCLIN D1; EPITHELIAL CELLS; LUNG; MALE; MICE; MICE, INBRED BALB C; PHOSPHORYLATION; RETINOBLASTOMA PROTEIN;

EID: 0035954828     PISSN: 03043835     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-3835(01)00480-3     Document Type: Article

References (47)

1. The role of Rb in cell cycle control
2. Retinoblastoma protein switches the E2F site from positive to negative element
3. Cdk phosphorylation triggers sequential intramolecular interactions that progressively block Rb functions as cells move through G1
4. Cloning and characterization of murine p16INK4a and p15INK4b genes
5. Cyclin D- and E-dependent kinases and the p57(KIP2) inhibitor: Cooperative interactions in vivo
6. Altered structure and expression of the human retinoblastoma susceptibility gene in small cell lung cancer
7. Prognostic significance of cyclin D1 and retinoblastoma expression in combination with p53 abnormalities in primary, resected non-small cell lung cancers
8. Primary lung tumors in mice: An experimentally manipulable model of human adenocarcinoma
9. Multiple molecular alterations in mouse lung tumors
10. Expression of cell cycle proteins in 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-induced mouse lung tumors
11. INK4a in mouse lung tumors
12. Inactivation of the INK4A/ARF locus frequently coexists with TP53 mutations in non-small cell lung cancer
13. Homozygous codeletion and differential decreased expression of p15 INK4β, p16 INK4a-α and p16 INK4a-β in mouse lung tumor cells
14. Role of the cytosine DNA-methyltransferase and p16INK4α genes in the development of mouse lung tumors
15. Mechanisms of p16INK4A inactivation in non small-cell lung cancers
16. Cyclin D1 overexpression vs. retinoblastoma inactivation: Implications for growth control evasion in non-small cell and small cell lung cancer
17. Inhibition of lung cancer proliferation by antisense cyclin D
18. Mouse lung epithelial cell lines - Tools for the study of differentiation and the neoplastic phenotype
19. Cloned murine non-malignant, spontaneously transformed, and chemical tumor-derived cell lines related to the type 2 pneumocyte
20. Characterization of a neoplastic epithelial cell strain derived by dexamethasone treatment of cultured normal mouse type 2 pneumocytes
21. 32P]-GTP into a 45 kDa protein in lung tumors
22. Ki-ras activation and expression in transformed mouse lung cell lines
23. Prevention of butylated hydroxytoluene-induced lung damage in mice by cedar terpene administration
24. A single gene in BALB/cBy J mice with a major effect on susceptibility to urethane-induced pulmonary adenoma
25. Protein measurement with the folin phenol reagent
26. 8-Cl-Adenosine mediates 8-Cl-cAMP induced down-regulation of cAMP-dependent protein kinase in normal and neoplastic mouse lung epithelial cells by a cAMP-independent mechanism
27. Two potentially oncogenic cyclins, cyclin A and cyclin D1, share common properties of subunit configuration, tyrosine phosphorylation and physical association with the Rb protein
28. Differential control of cyclins D1 and D3 and the cdk inhibitor p27 KIP1 by diverse signaling pathways in Swiss 3T3 cells
29. Lung damage in mice following intraperitoneal injection of butylated hydroxytoluene
30. Lung injury induced by butylated hydroxytoluene: Cytodynamic and biochemical studies in mice
31. Metabolism and pulmonary toxicity of butylated hydroxytoluene (BHT)
32. Stimulation of DNA synthesis in mouse lung following intraperitoneal injection of butylated hydroxytoluene
33. Compensatory lung growth following partial pneumonectomy enhances lung tumorigenesis induced by 3-methylcholanthrene
34. Genetic variation in the proliferation of murine pulmonary type II cells: Basal rates and alterations following urethane treatment
35. Proliferating cell nuclear antigen (PCNA/Cyclin) immunocytochemistry as a labeling index in mouse lung tissues
36. Growth inhibition in G1 and altered expression of cyclin D1 and p27 kip-1 after forced connexin expression in lung and liver carcinoma cells
37. Cdkn2a encodes functional variation of p16INK4α but not p19ARF, which confers selection in mouse lung tumorigenesis
38. RAS and ERBB 2
39. The role of alveolar type 2 cells in the development and progression of pulmonary tumors in the A/J mouse
40. Ki-ras and p53 mutations are early and late events, respectively, in urethane-induced pulmonary carcinogenesis in A/J mice
41. Molecular comparison of human and mouse pulmonary adenocarcinomas
42. Reduced receptor expression for platelet-derived growth factor and epidermal growth factor in dividing mouse lung epithelial cells
43. Growth factors, cytokines and soluble forms of receptor molecules in cancer patients
44. Decreased expression of the type I isozyme of cAMP-dependent protein kinase in tumor cell lines of lung epithelial origin
45. Autocrine loops, signal transduction, and cell cycle abnormalities in the molecular biology of lung cancer
46. Growth inhibitory effect of anti-K-ras adenovirus on lung cancer cells
47. Adenovirus-mediated p53 gene transfer in advanced non-small-cell lung cancer