메뉴 건너뛰기




Volumn 146, Issue 43, 2001, Pages 10-16

Drug development: Continuing application of newly developed methods for combinatorial chemistry and natural-product screening;Maßgeschneiderte nadeln aus dem kombinatorischen heuhaufen

Author keywords

[No Author keywords available]

Indexed keywords

4 [(4 BROMOPHENYL)(ETHOXYIMINO)METHYL] 1' [(2,4 DIMETHYL 3 PYRIDINYL)CARBONYL] 4' METHYL 1,4' BIPIPERIDINE; ACETYLCHOLINESTERASE; ALDEHYDE; ALPHA N ACETYLNONA DEXTRO ARGININE AMIDE; AMD 7049; HYDRAZIDE; N (6 AMINOHEXYL)GLYCYL N (3 GUANIDINOPROPYL)GLYCYL N (3 GUANIDINOPROPYL)GLYCYL N BENZYLGLYCYL N (3 GUANIDINOPROPYL)GLYCYL DEXTRO LYSYL DEXTRO LYSYL DEXTRO ARGINYL DEXTRO PROLINAMIDE; N [4 [[[6,7 DIHYDRO 2 (4 METHYLPHENYL) 5H BENZOCYCLOHEPTEN 8 YL]CARBONYL]AMINO]BENZYL] N,N DIMETHYL 2H TETRAHYDROPYRAN 4 AMINIUM CHLORIDE; NATURAL PRODUCT; PEPTIDE DERIVATIVE; POLYMER; UNCLASSIFIED DRUG;

EID: 0035950289     PISSN: 00317136     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (1)

References (29)
  • 2
    • 0001723417 scopus 로고    scopus 로고
    • Design kombinatorischer Leitstruktur-Bibliotheken
    • (1999) Angew. Chem. , vol.111 , Issue.24 , pp. 3962-3967
    • Teague, S.J.1
  • 4
    • 0031024171 scopus 로고    scopus 로고
    • Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings
    • (1997) Adv. Drug Delivery Rev. , vol.46 , Issue.1 , pp. 3-25
    • Lipinski, C.1
  • 5
    • 0035347869 scopus 로고    scopus 로고
    • Scaffold architecture and pharmacophoric properties of natural products and trade drugs: Application in the design of natural product-based combinatorial libraries
    • (2001) J. Comb. Chem. , vol.3 , Issue.3 , pp. 284-289
    • Lee, M.L.1    Schneider, G.2
  • 9
    • 0033964548 scopus 로고    scopus 로고
    • Traceless linking of indoles: General methodology and application to solid phase supported mannich and stille reactions
    • (2000) Synlett , Issue.1 , pp. 125-127
    • Kraxner, J.1    Arlt, J.2    Gmeiner, P.3
  • 11
    • 0035382954 scopus 로고    scopus 로고
    • Discovery of Novel Antibacterial Agents Active against methicillin-resistant staphylococcus aureus from combinatorial benzopyran libraries
    • (2001) ChemBioChem , vol.2 , Issue.6 , pp. 460-465
    • Nicolaou, K.C.1
  • 12
    • 0034700141 scopus 로고    scopus 로고
    • The design, synthesis, and evaluation of molecules that enable or enhance cellular uptake: Peptoid molecular transporters
    • (2000) Proc. Natl. Acad. Sci. USA , vol.97 , Issue.24 , pp. 13003-13008
    • Wender, P.A.1
  • 13
    • 20144365291 scopus 로고    scopus 로고
    • DNA-binding ligands from peptide libraries containing unnatural amino acids
    • (1998) Chem. Eur. J. , vol.4 , Issue.3 , pp. 425-433
    • Lescrinier, T.1
  • 14
    • 0032515908 scopus 로고    scopus 로고
    • A new class of HIV-1 Tat antagonist acting through Tat-TAR inhibition
    • (1998) Biochemistry , vol.37 , Issue.15 , pp. 5086-5095
    • Hamy, F.1
  • 15
    • 0033678653 scopus 로고    scopus 로고
    • Conjugation of arginine oligomers to cyclosporin A facilitates topical delivery and inhibition of inflammation
    • (2000) Nat. Med. , vol.6 , Issue.11 , pp. 1253-1257
    • Rothbard, J.B.1
  • 16
    • 0029911702 scopus 로고    scopus 로고
    • Anti-human immunodeficiency virus type 1 activity of an oligocationic compound mediated via Gp120 V3 Interactions
    • (1996) J. Virol. , vol.70 , Issue.5 , pp. 2825-2831
    • O'Brien, W.1
  • 17
    • 0030773515 scopus 로고    scopus 로고
    • A small-molecule inhibitor directed against the chemokine receptor CXCR4 prevents its use as an HIV-1 coreceptor
    • (1997) J. Exp. Med. , vol.186 , Issue.8 , pp. 1395-1400
    • Doranz, B.J.1
  • 19
    • 0035382539 scopus 로고    scopus 로고
    • Dynamic deconvolution of a pre-equilibrated dynamic combinatorial library of acetylcholinesterase inhibitors
    • (2001) ChemBioChem , vol.2 , Issue.6 , pp. 438-444
    • Bunyapaiboonsri, T.1
  • 21
    • 0034263911 scopus 로고    scopus 로고
    • Polymer-assisted solution phase synthesis of 2′-amino-2′-deoxyadenosines targeted at the NAD+-binding sites of parasite enzymes
    • (2000) J. Comb. Chem. , vol.2 , Issue.5 , pp. 537-544
    • Golisade, A.1
  • 23
    • 0000718603 scopus 로고    scopus 로고
    • Sequentielle nucleophile Substitution: Eine effiziente strategie zur synthese von substanzbibliotheken hoher diversität an festen trägern
    • (2000) Angew. Chem. , vol.112 , Issue.3 , pp. 565-567
    • Zaragoza, F.1    Stephensen, H.2
  • 24
    • 25544452566 scopus 로고    scopus 로고
    • Terminologie für die Anwendung temporär gebundener, löslichkeitsmodifizierender auxiliare in der kombinatorischen chemie - Ein kritischer kommentar
    • (2000) Angew. Chem. , vol.112 , Issue.22 , pp. 4203-4205
    • Link, A.1
  • 25
    • 0033583107 scopus 로고    scopus 로고
    • Liquid-phase synthesis with solid-phase workup: Application to multistep and combinatorial syntheses
    • (1999) J. Org. Chem. , vol.64 , Issue.6 , pp. 2110-2113
    • Perrier, H.1    Labelle, M.2
  • 26
    • 0001493280 scopus 로고    scopus 로고
    • Precipitons - Functional Protecting groups to facilitate product separation: Applications in isoxazoline synthesis
    • (2001) Angew. Chem. , vol.113 , Issue.10 , pp. 1927-1931
    • Bosanac, T.1    Yang, J.2    Wilcox, C.3
  • 27


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.