Discovery of a new class of p38 kinase inhibitors

Bioorganic and Medicinal Chemistry Letters

Volumn 10, Issue 18, 2000, Pages 2047-2050

  Dumas, Jacques ^a   Sibley, Robert ^a   Riedl, Bernd ^a   Monahan, Mary Katherine ^a   Lee, Wendy ^a   Lowinger, Timothy B ^a   Redman, Anikó M ^a   Johnson, Jeffrey S ^a   Kingery Wood, Jill ^a   Scott, William J ^a   Smith, Roger A ^a   Bobko, Mark ^a   Schoenleber, Robert ^a   Ranges, Gerald E ^a   Housley, Timothy J ^a   Bhargava, Ajay ^a   Wilhelm, Scott M ^a   Shrikhande, Alka ^a  

^a BAYER CORPORATION   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

INTERLEUKIN 1; INTERLEUKIN 6; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; RECOMBINANT TUMOR NECROSIS FACTOR ALPHA;

ARTICLE; CHONDROSARCOMA; CYTOKINE PRODUCTION; DRUG SYNTHESIS; HUMAN; HUMAN CELL; SIGNAL TRANSDUCTION; STRUCTURE ACTIVITY RELATION;

ANTIRHEUMATIC AGENTS; COMBINATORIAL CHEMISTRY TECHNIQUES; ENZYME INHIBITORS; HETEROCYCLIC COMPOUNDS; HUMANS; HYDROCARBONS, CHLORINATED; INHIBITORY CONCENTRATION 50; MITOGEN-ACTIVATED PROTEIN KINASES; OSTEOPOROSIS; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHENYLUREA COMPOUNDS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0033813234     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(00)00270-5     Document Type: Article

References (24)