Synthesis of sulfaphenazole derivatives and their use as inhibitors and tools for comparing the active sites of human liver cytochromes P450 of the 2C subfamily

Journal of Medicinal Chemistry

Volumn 44, Issue 22, 2001, Pages 3622-3631

  Ha Duong, N T ^a   Dijols, S ^a   Marques Soares, C ^a   Minoletti, C ^a   Dansette, P M ^a   Mansuy, D ^a  

^a UNIVERSITÉ PARIS DESCARTES   (France)

Author keywords

[No Author keywords available]

Indexed keywords

AMMONIA; CYTOCHROME C2; CYTOCHROME P450; HYDROGEN; SULFAPHENAZOLE;

ALKYLATION; ARTICLE; ENZYME ACTIVE SITE; HUMAN; LIVER; LIVER MICROSOME; SYNTHESIS;

ARYL HYDROCARBON HYDROXYLASES; BINDING SITES; CYTOCHROME P-450 ENZYME SYSTEM; ENZYME INHIBITORS; HUMANS; LIVER; MICROSOMES; MIXED FUNCTION OXYGENASES; RECOMBINANT PROTEINS; STEROID 16-ALPHA-HYDROXYLASE; STEROID HYDROXYLASES; STRUCTURE-ACTIVITY RELATIONSHIP; SULFAPHENAZOLE; SULFONAMIDES; YEASTS;

EID: 0035950125     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm010861y     Document Type: Article

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