HBV X protein targets HIV Tat-binding protein 1

Virology

Volumn 283, Issue 1, 2001, Pages 110-120

  Barak, Orr ^a   Aronheim, Ami ^b   Shaul, Yosef ^a  

^a WEIZMANN INSTITUTE OF SCIENCE   (Israel)

^b TECHNION ISRAEL INSTITUTE OF TECHNOLOGY   (Israel)

Author keywords

19S; AAA protein family; HBV pX; HCC; Sos recruitment system (SRS); Transcription

Indexed keywords

BINDING PROTEIN; HEPATITIS B VIRUS X PROTEIN; PROTEASOME; PROTEIN SUG 1; TAT BINDING PROTEIN 1; UNCLASSIFIED DRUG; VIRUS LARGE T ANTIGEN; VIRUS PROTEIN;

ADENOVIRUS; ARTICLE; GENE TARGETING; HEPATITIS B VIRUS; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS; LIVER CELL CARCINOMA; NONHUMAN; PRIORITY JOURNAL; PROTEIN MOTIF; PROTEIN PROTEIN INTERACTION; PROTEIN TARGETING; VIRUS CELL INTERACTION; VIRUS PARTICLE; VIRUS TRANSCRIPTION;

EID: 0035946294     PISSN: 00426822     EISSN: None     Source Type: Journal    
DOI: 10.1006/viro.2001.0883     Document Type: Article

References (55)

1. Improved efficiency sos recruitment system: Expression of the mammalian GAP reduces isolation of Ras GTPase false positives
2. Membrane targeting of the nucleotide exchange factor Sos is sufficient for activating the Ras signaling pathway
3. Isolation of an AP-1 repressor by a novel method for detecting protein-protein interactions
4. Three tumor-suppressor regions on chromosome 11p identified by high-resolution deletion mapping in human non-small-cell lung cancer
5. Sequence analysis of the AAA protein family
6. Human RPB5, a subunit shared by eukaryotic nuclear RNA polymerases, binds human hepatitis B virus X protein and may play a role in X transactivation
7. The hepatitis B virus X-associated protein, XAP3, is a protein kinase C-binding protein
8. Hepatitis B virus-induced hepatocellular carcinoma: Possible roles for HBx
9. PA700, an ATP-dependent activator of the 20 S proteasome, is an ATPase containing multiple members of a nucleotide-binding protein family
10. The X protein of hepatitis B virus has a ribo/deoxy ATPase activity
11. HBV transcription repression in response to genotoxic stress is p53-dependent and abrogated by pX
12. A novel genetic system to detect protein-protein interactions
13. SUG1, a putative transcriptional mediator and subunit of the PA700 proteasome regulatory complex, is a DNA helicase
14. The regulatory particle of the Saccharomyces cerevisiae proteasome
15. Adenovirus early region 1A protein binds to mammalian SUG1 - A regulatory component of the proteasome
16. pX, the HBV-encoded coactivator, suppresses the phenotypes of TBP and TAFII250 mutants
17. Hepatitis B virus pX targets TFIIB in transcription coactivation
18. The X protein of hepatitis B virus coactivates potent activation domains
19. pX, the HBV-encoded coactivator, interacts with components of the transcription machinery and stimulates transcription in a TAF-independent manner
20. Localization of genes encoding two human one-domain members of the AAA family: PSMC5 (the thyroid hormone receptor-interacting protein, TRIP1) and PSMC3 (the Tat-binding protein, TBP1)
21. Hepatitis B virus X protein is both a substrate and a potential inhibitor of the proteasome complex
22. Proteasome complex as a potential cellular target of hepatitis B virus X protein
23. Hepatitis B virus X protein inhibits nucleotide excision repair
24. A multiprotein mediator of transcriptional activation and its interaction with the C-terminal repeat domain of RNA polymerase II
25. Activation of Src family kinases by hepatitis B virus HBx protein and coupled signaling to Ras
26. XAP2, a novel hepatitis B virus X-associated protein that inhibits X transactivation
27. Hepatitis B virus X protein interacts with a probable cellular DNA repair protein
28. Hepatitis B virus X protein is a transcriptional modulator that communicates with transcription factor IIB and the RNA polymerase II subunit 5
29. HBV X protein alters the DNA binding specificity of CREB and ATF-2 by protein-protein interactions
30. SUG1, a component of the 26S proteasome, is an ATPase stimulated by specific RNAs
31. Multiple mammalian proteasomal ATPases, but not proteasome itself, are associated with TATA-binding protein and a novel transcriptional activator, TIP120
32. A cDNA for a protein that interacts with the human immunodeficiency virus Tat transactivator
33. The type 1 human immunodeficiency virus Tat binding protein is a transcriptional activator belonging to an additional family of evolutionarily conserved genes
34. p53 binds and represses the HBV enhancer: An adjacent enhancer element can reverse the transcription effect of p53
35. Induction of the Tat-binding protein 1 gene accompanies the disabling of oncogenic erbB receptor tyrosine kinases
36. The hepatitis B pX protein promotes dimerization and DNA binding of cellular basic region/leucine zipper proteins by targeting the conserved basic region
37. Hepatitis B virus transactivator protein, HBx, associates with the components of TFIIH and stimulates the DNA helicase activity of TFIIH
38. Identification of the gal4 suppressor Sug1 as a subunit of the yeast 26S proteasome
39. Two-codon insertion mutations of the HBx define two separate regions necessary for its trans-activation function
40. The 19S regulatory complex of the proteasome functions independently of proteolysis in nucleotide excision repair
41. Subcellular localization, stoichiometry, and protein levels of 26S proteasome subunits in yeast
42. Functional overlap of sequences that activate transcription and signal ubiquitin-mediated proteolysis
43. Identification of a set of yeast genes coding for a novel family of putative ATPases with high similarity to constituents of the 26S protease complex
44. HIV-1 Tat inhibits the 20 S proteasome and its 11 S regulator-mediated activation
45. Loss of heterozygosity on chromosome 11p13 in primary bladder carcinoma
46. Cytosol is the prime compartment of hepatitis B virus X protein where it colocalizes with the proteasome
47. Alterations in a yeast protein resembling HIV Tat-binding protein relieve requirement for an acidic activation domain in GAL4
48. A highly conserved ATPase protein as a mediator between acidic activation domains and the TATA-binding protein
49. Three sites of the hepatitis B virus X protein cooperatively interact with cellular proteins
50. Differential ligand-dependent interactions between the AF-2 activating domain of nuclear receptors and the putative transcriptional intermediary factors mSUG1 and TIF1
51. Hepatitis B virus X protein inhibits p53 sequence-specific DNA binding, transcriptional activity, and association with transcription factor ERCC3
52. The XPB subunit of repair/transcription factor TFIIH directly interacts with SUG1, a subunit of the 26S proteasome and putative transcription factor
53. Direct association and nuclear import of the hepatitis B virus X protein with the NF-kappaB inhibitor IkappaBalpha
54. The hepatitis B virus X protein targets the basic region-leucine zipper domain of CREB
55. Structural and functional characterization of interaction between hepatitis B virus X protein and the proteasome complex