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Volumn 58, Issue SUPPL. 3, 1999, Pages 57-69

New oral chemotherapeutic agents for lung cancer

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; BEXAROTENE; CARBOPLATIN; CISPLATIN; CYCLOPHOSPHAMIDE; CYTOTOXIC AGENT; DOXORUBICIN; IRINOTECAN; MATRIX METALLOPROTEINASE INHIBITOR; NAVELBINE; PLATINUM; SATRAPLATIN; TANOMASTAT; TOPOTECAN; UFT; VINBLASTINE; VINCRISTINE; VINDESINE;

EID: 0033504003     PISSN: 00126667     EISSN: None     Source Type: Journal    
DOI: 10.2165/00003495-199958003-00009     Document Type: Conference Paper
Times cited : (13)

References (137)
  • 2
    • 0028843552 scopus 로고
    • Chemotherapy in non-small cell lung cancer: A meta-analysis using updated data on individual patients from 52 randomised clinical trials. Non-small cell lung cancer collaborative group
    • Anonymous. Chemotherapy in non-small cell lung cancer: a meta-analysis using updated data on individual patients from 52 randomised clinical trials. Non-small Cell Lung Cancer Collaborative Group. BMJ 1995; 311: 899-909
    • (1995) BMJ , vol.311 , pp. 899-909
  • 3
    • 0001773102 scopus 로고    scopus 로고
    • Mitomycin, ifosfamide and cisplatin in non-small cell lung cancer: 2. Results of a randomised trial in patients with extensive disease
    • Cullen MH, Woodroffe CM, Billingham L.J, et al. Mitomycin, ifosfamide and cisplatin in non-small cell lung cancer: 2. Results of a randomised trial in patients with extensive disease-Lung Cancer 1997; 18 Suppl. 1: 5
    • (1997) Lung Cancer , vol.18 , Issue.SUPPL. 1 , pp. 5
    • Cullen, M.H.1    Woodroffe, C.M.2    Billingham, L.J.3
  • 4
    • 0020854087 scopus 로고
    • On the receiving end-II. Linear analogue self-assessment (LASA) in evaluation of aspects of the quality of life of cancer patients receiving therapy
    • Coates A, Dillenbeck CF, McNeil DR, et al. On the receiving end-II. Linear analogue self-assessment (LASA) in evaluation of aspects of the quality of life of cancer patients receiving therapy. Eur J Cancer Clin Oncol 1983; 19: 1633-7
    • (1983) Eur J Cancer Clin Oncol , vol.19 , pp. 1633-1637
    • Coates, A.1    Dillenbeck, C.F.2    McNeil, D.R.3
  • 5
    • 0020699588 scopus 로고
    • On the receiving end-patient perception of the side-effects of cancer chemotherapy
    • Coates A, Abraham S, Kaye SB, et al. On the receiving end-patient perception of the side-effects of cancer chemotherapy. Eur J Cancer Clin Oncol 1983; 19: 203-8
    • (1983) Eur J Cancer Clin Oncol , vol.19 , pp. 203-208
    • Coates, A.1    Abraham, S.2    Kaye, S.B.3
  • 6
    • 0024337159 scopus 로고
    • Biochemical effects of Navelbine® on tubulin and associated proteins
    • Fellous A, Ohayon R, Vacassin T, et al. Biochemical effects of Navelbine® on tubulin and associated proteins. Semin Oncol 1989; 16 Suppl. 4:9-14
    • (1989) Semin Oncol , vol.16 , Issue.SUPPL. 4 , pp. 9-14
    • Fellous, A.1    Ohayon, R.2    Vacassin, T.3
  • 7
    • 0024474775 scopus 로고
    • The synthesis of Navelbine® - Prototype of a new series of vinblastine derivatives
    • Potier P. The synthesis of Navelbine® - prototype of a new series of vinblastine derivatives. Semin Oncol 1989; 16 Suppl. 4: 2-4
    • (1989) Semin Oncol , vol.16 , Issue.SUPPL. 4 , pp. 2-4
    • Potier, P.1
  • 8
    • 0024379852 scopus 로고
    • In situ analysis of the action of Navelbine on various types of microtubules using immunofluorescence
    • Binet S, Fellous A, Lataste H, et al. In situ analysis of the action of Navelbine on various types of microtubules using immunofluorescence. Semin Oncol 1989; 16 Suppl. 4: 5-8
    • (1989) Semin Oncol , vol.16 , Issue.SUPPL. 4 , pp. 5-8
    • Binet, S.1    Fellous, A.2    Lataste, H.3
  • 9
    • 0025160828 scopus 로고
    • Immunofluorescence study of the action of navelbine, vincristine and vinblastine on mitotic and axonal microtubules
    • Binet S, Chaineau E, Fellous A, et al. Immunofluorescence study of the action of navelbine, vincristine and vinblastine on mitotic and axonal microtubules. Int J Cancer 1990; 46: 262-6
    • (1990) Int J Cancer , vol.46 , pp. 262-266
    • Binet, S.1    Chaineau, E.2    Fellous, A.3
  • 10
    • 0024364114 scopus 로고
    • Pharmacokinetics and metabolism of Navelbine®
    • Krikorian A, Rahmani R, Bromet M, et al. Pharmacokinetics and metabolism of Navelbine®. Semin Oncol 1989; 16 Suppl. 4:21-5
    • (1989) Semin Oncol , vol.16 , Issue.SUPPL. 4 , pp. 21-25
    • Krikorian, A.1    Rahmani, R.2    Bromet, M.3
  • 11
    • 0019124123 scopus 로고
    • Comparative pharmacokinetics of vindesine, vincristine, and vinblastine in patients with cancer
    • Nelson R, Dyke RW, Root MA. Comparative pharmacokinetics of vindesine, vincristine, and vinblastine in patients with cancer. Cancer Treat Rev 1980; 7 Suppl. 1: 17-24
    • (1980) Cancer Treat Rev , vol.7 , Issue.SUPPL. 1 , pp. 17-24
    • Nelson, R.1    Dyke, R.W.2    Root, M.A.3
  • 12
    • 0020027577 scopus 로고
    • The comparative clinical pharmacology and pharmacokinetics of vindesine, vincristine, and vinblastine in human patients with cancer
    • Nelson R. The comparative clinical pharmacology and pharmacokinetics of vindesine, vincristine, and vinblastine in human patients with cancer. Med Pediatr Oncol 1982; 10: 115-27
    • (1982) Med Pediatr Oncol , vol.10 , pp. 115-127
    • Nelson, R.1
  • 13
    • 0027435310 scopus 로고
    • Pulmonary distribution of vinorelbine in patients with non-small cell lung cancer
    • Leveque D, Quoix E, Dumont P, et al. Pulmonary distribution of vinorelbine in patients with non-small cell lung cancer. Cancer Chemother Pharmacol 1993; 33: 176-8
    • (1993) Cancer Chemother Pharmacol , vol.33 , pp. 176-178
    • Leveque, D.1    Quoix, E.2    Dumont, P.3
  • 14
    • 0028154069 scopus 로고
    • Randomized study of vinorelbine and cisplatin versus vindesinc and cisplatin versus vinorelbine alone in advanced non-small-cell lung cancer: Results of a european multicenter trial including 612 patients
    • Le Chevalier T, Brisgand D, Douillard JY, et al. Randomized study of vinorelbine and cisplatin versus vindesinc and cisplatin versus vinorelbine alone in advanced non-small-cell lung cancer: results of a European multicenter trial including 612 patients. J Clin Oncol 1994; 12: 360-7
    • (1994) J Clin Oncol , vol.12 , pp. 360-367
    • Le Chevalier, T.1    Brisgand, D.2    Douillard, J.Y.3
  • 15
    • 0343744663 scopus 로고
    • Vincaleukoblastine III. Clinical trial with the oral preparation
    • Hodes M, Rohn R, Bond W. Vincaleukoblastine III. Clinical trial with the oral preparation. Cancer Chemother Rep 1961, 14: 129-38
    • (1961) Cancer Chemother Rep , vol.14 , pp. 129-138
    • Hodes, M.1    Rohn, R.2    Bond, W.3
  • 16
    • 0343744664 scopus 로고
    • Oral administration of vinblastine sulfate (NSC-49842) to cancer patients
    • Korst DR, Nixon JC. Oral administration of vinblastine sulfate (NSC-49842) to cancer patients. Cancer Chemother Rep 1965; 45: 53-6
    • (1965) Cancer Chemother Rep , vol.45 , pp. 53-56
    • Korst, D.R.1    Nixon, J.C.2
  • 18
    • 0014115486 scopus 로고
    • The response of Hodgkin's disease to treatment with oral vinblastine sulfate
    • Wilson HE, Louis J. The response of Hodgkin's disease to treatment with oral vinblastine sulfate. Ann Intern Med 1967; 67: 303-8
    • (1967) Ann Intern Med , vol.67 , pp. 303-308
    • Wilson, H.E.1    Louis, J.2
  • 19
    • 0029843025 scopus 로고    scopus 로고
    • Clinical pharmacokinetics of vinorelbine
    • Leveque D, Jehl F. Clinical pharmacokinetics of vinorelbine. Clin Pharmacokinet 1996; 31: 184-97
    • (1996) Clin Pharmacokinet , vol.31 , pp. 184-197
    • Leveque, D.1    Jehl, F.2
  • 20
    • 0025949951 scopus 로고
    • Pharmacokinetics of Navelbine after oral administration in cancer patients
    • Zhou XJ, Bore P, Monjanel S, et al. Pharmacokinetics of Navelbine after oral administration in cancer patients. Cancer Chemother Pharmacol 1991; 29: 66-70
    • (1991) Cancer Chemother Pharmacol , vol.29 , pp. 66-70
    • Zhou, X.J.1    Bore, P.2    Monjanel, S.3
  • 21
    • 0027987481 scopus 로고
    • Pharmacokinetic, bioavailability, and feasibility study of oral vinorelbine in patients with solid tumors
    • Rowinsky EK, Noe DA, Trump DL, et al. Pharmacokinetic, bioavailability, and feasibility study of oral vinorelbine in patients with solid tumors. J Clin Oncol 1994; 12: 1754-63
    • (1994) J Clin Oncol , vol.12 , pp. 1754-1763
    • Rowinsky, E.K.1    Noe, D.A.2    Trump, D.L.3
  • 22
    • 0024591753 scopus 로고
    • Pharmacokinetics of a new anticancer drug, navelbine, in patients
    • Bore P, Rahmani R, Van Cantfort J, et al. Pharmacokinetics of a new anticancer drug, navelbine, in patients. Cancer Chemother Pharmacol 1989; 23: 247-51
    • (1989) Cancer Chemother Pharmacol , vol.23 , pp. 247-251
    • Bore, P.1    Rahmani, R.2    Van Cantfort, J.3
  • 23
    • 0025904173 scopus 로고
    • Pharmacokinetic and preliminary metabolic fate of navelbine in humans as determined by high performance liquid chromatography
    • Jehl F, Quoix E, Leveque D, et al. Pharmacokinetic and preliminary metabolic fate of navelbine in humans as determined by high performance liquid Chromatography. Cancer Res 1991; 51: 2073-6
    • (1991) Cancer Res , vol.51 , pp. 2073-2076
    • Jehl, F.1    Quoix, E.2    Leveque, D.3
  • 24
    • 0027996614 scopus 로고
    • The clinical pharmacokinetics of vinorelbine (navelbine)
    • Wargin WA, Lucas VS. The clinical pharmacokinetics of vinorelbine (navelbine). Semin Oncol 1994; 21 Suppl. 10: 21-7
    • (1994) Semin Oncol , vol.21 , Issue.SUPPL. 10 , pp. 21-27
    • Wargin, W.A.1    Lucas, V.S.2
  • 25
    • 0007769152 scopus 로고
    • Phase I trial of escalating doses of orally administered Navelbine. Pt II. Clinical results
    • Favre R, Delgado M, Besenval M. Phase I trial of escalating doses of orally administered Navelbine. Pt II. Clinical results. Proc Am Soc Clin Oncol 1989; 8: 64A
    • (1989) Proc Am Soc Clin Oncol , vol.8
    • Favre, R.1    Delgado, M.2    Besenval, M.3
  • 26
    • 0007812281 scopus 로고
    • Phase I trial of escalating doses of orally administered Navelbine. Pt I. Pharmacokinetics
    • Rahmani R, Bore P, Cano JP. Phase I trial of escalating doses of orally administered Navelbine. Pt I. Pharmacokinetics. Proc Am Soc Clin Oncol 1989; 8: 74A
    • (1989) Proc Am Soc Clin Oncol , vol.8
    • Rahmani, R.1    Bore, P.2    Cano, J.P.3
  • 27
    • 0026199875 scopus 로고
    • 3H]navelbine in patients: Comparative pharmacokinetics using radioactive and radioimmunologic determination methods
    • 3H]Navelbine in patients: comparative pharmacokinetics using radioactive and radioimmunologic determination methods. Anticancer Drugs 1991; 2: 405-10
    • (1991) Anticancer Drugs , vol.2 , pp. 405-410
    • Rahmani, R.1    Zhou, X.J.2    Bore, P.3
  • 28
    • 84912874846 scopus 로고
    • Clinical results of a study of the absolute bioavailability and pharmacokinetics of weekly vinorelbine liquid-filled soft gelatin capsules at full therapeutic doses in patients with solid tumors
    • Lucas S, Donehower R, Rowinsky E. Clinical results of a study of the absolute bioavailability and pharmacokinetics of weekly vinorelbine liquid-filled soft gelatin capsules at full therapeutic doses in patients with solid tumors. Proc Am Soc Clin Oncol 1992; 11: 287A
    • (1992) Proc Am Soc Clin Oncol , vol.11
    • Lucas, S.1    Donehower, R.2    Rowinsky, E.3
  • 29
    • 0028064823 scopus 로고
    • Relative bioavailability of two oral formulations of navelbine in cancer patients
    • Zhou XJ, Zhou-Pan XR, Favre R, et al. Relative bioavailability of two oral formulations of navelbine in cancer patients. Biopharm Drug Dispos 1994; 15: 577-86
    • (1994) Biopharm Drug Dispos , vol.15 , pp. 577-586
    • Zhou, X.J.1    Zhou-Pan, X.R.2    Favre, R.3
  • 30
    • 0028931164 scopus 로고
    • Multicenter phase Il study of weekly oral vinorelbine fur stage IV non-small-cell lung cancer
    • Vokes EE, Rosenberg RK, Jahanzeb M, et al. Multicenter phase Il study of weekly oral vinorelbine fur stage IV non-small-cell lung cancer. J Clin Oncol 1995; 13: 637-44
    • (1995) J Clin Oncol , vol.13 , pp. 637-644
    • Vokes, E.E.1    Rosenberg, R.K.2    Jahanzeb, M.3
  • 31
    • 0025910655 scopus 로고
    • A phase II study of Navelbine (vinorelbine) in the treatment of non-small-cell lung cancer
    • Depierre A, Lemarie E, Dabouis G, et al. A Phase II study of Navelbine (vinorelbine) in the treatment of non-small-cell lung cancer. Am J Clin Oncol 1991; 14: 115-9
    • (1991) Am J Clin Oncol , vol.14 , pp. 115-119
    • Depierre, A.1    Lemarie, E.2    Dabouis, G.3
  • 32
    • 10144246570 scopus 로고    scopus 로고
    • Randomized trial of vinorelbine compared with fluorouracil plus leucovorin in patients with stage IV non-small-cell lung cancer
    • Crawford J, O'Rourke M, Schiller JH, et al. Randomized trial of vinorelbine compared with fluorouracil plus leucovorin in patients with stage IV non-small-cell lung cancer. J Clin Oncol 1996; 14: 2774-84
    • (1996) J Clin Oncol , vol.14 , pp. 2774-2784
    • Crawford, J.1    O'Rourke, M.2    Schiller, J.H.3
  • 33
    • 4244097603 scopus 로고
    • Oral navelbine in women with previously treated advanced breast cancer: A US multicenler phase II trial
    • Spicer D, McCaskill-Stevens W, Oken M, et al. Oral Navelbine in women with previously treated advanced breast cancer: a US multicenler Phase II trial. Proc Am Soc Clin Oncol 1994; 13: 76A
    • (1994) Proc Am Soc Clin Oncol , vol.13
    • Spicer, D.1    McCaskill-Stevens, W.2    Oken, M.3
  • 34
    • 4243682012 scopus 로고
    • Results of a study of the effect of food on the bioavailability and pharmacokinetics of Navelbine® liquid-filled soft gelatin capsules
    • Lucas S, Rowinsky E, Wargin W. Results of a study of the effect of food on the bioavailability and pharmacokinetics of Navelbine® liquid-filled soft gelatin capsules. Proc Am Soc Clin Oncol 1993; 12: 160A
    • (1993) Proc Am Soc Clin Oncol , vol.12
    • Lucas, S.1    Rowinsky, E.2    Wargin, W.3
  • 35
    • 0029820708 scopus 로고    scopus 로고
    • The effects of food and divided dosing on the hioavailahility of oral vinorelbine
    • Rowinsky EK, Lucas VS, Hsieh AL, et al. The effects of food and divided dosing on the hioavailahility of oral vinorelbine. Cancer Chemother Pharmacol 1996; 39: 9-16
    • (1996) Cancer Chemother Pharmacol , vol.39 , pp. 9-16
    • Rowinsky, E.K.1    Lucas, V.S.2    Hsieh, A.L.3
  • 36
    • 0029048587 scopus 로고
    • Oral vinorelbine (navelbine) in the treatment of advanced breast cancer
    • Winer EP, Chu L, Spicer DV. Oral vinorelbine (navelbine) in the treatment of advanced breast cancer. Semin Oncol 1995; 22 Suppl. 5: 72-8
    • (1995) Semin Oncol , vol.22 , Issue.SUPPL. 5 , pp. 72-78
    • Winer, E.P.1    Chu, L.2    Spicer, D.V.3
  • 37
    • 0343744658 scopus 로고
    • Pharmacokinetics of vinorelbine in breast cancer patients with liver metastases
    • Robieux I, Sorio R, Vitali V, et al. Pharmacokinetics of vinorelbine in breast cancer patients with liver metastases. Proc Am Soc Clin Oncol 1995; 14: 458A
    • (1995) Proc Am Soc Clin Oncol , vol.14
    • Robieux, I.1    Sorio, R.2    Vitali, V.3
  • 38
    • 37049053957 scopus 로고
    • Inhibition of cell division in Escherichia coli by electrolysis products from a platinum electrode
    • Rosenberg B, Van Camp L, Krigas T. Inhibition of cell division in Escherichia coli by electrolysis products from a platinum electrode. Nature 1965; 205: 698-9
    • (1965) Nature , vol.205 , pp. 698-699
    • Rosenberg, B.1    Van Camp, L.2    Krigas, T.3
  • 39
    • 0014216382 scopus 로고
    • The inhibition of growth or cell division in Escherichia coli by different ionic species of platinum (IV) complexes
    • Rosenberg B, Van Camp L, Grimley EB, et al. The inhibition of growth or cell division in Escherichia coli by different ionic species of platinum (IV) complexes. J Biol Chem 1967; 242: 1347-52
    • (1967) J Biol Chem , vol.242 , pp. 1347-1352
    • Rosenberg, B.1    Van Camp, L.2    Grimley, E.B.3
  • 40
    • 0014691619 scopus 로고
    • Platinum compounds: A new class of potent antitumor agents
    • Rosenberg B, Van Camp L, Trosko JE, et al. Platinum compounds: a new class of potent antitumor agents. Nature 1969; 222: 385-6
    • (1969) Nature , vol.222 , pp. 385-386
    • Rosenberg, B.1    Van Camp, L.2    Trosko, J.E.3
  • 41
    • 0016210403 scopus 로고
    • Diammine-dichloroplatinum: A phase I study showing responses in testicular and other tumors
    • Higby DJ, Wallace HJ, Albert DJ, et al. Diammine-dichloroplatinum: a Phase I study showing responses in testicular and other tumors. Cancer 1974; 33: 1219-25
    • (1974) Cancer , vol.33 , pp. 1219-1225
    • Higby, D.J.1    Wallace, H.J.2    Albert, D.J.3
  • 42
    • 0010458213 scopus 로고
    • Antitumor, toxic and biochemical properties of cisplatin and eight other platinum complexes
    • Prestayko AW, editor. New York: Academic Press
    • Harrap KR, Jones M, Wilkinson CR, et al. Antitumor, toxic and biochemical properties of cisplatin and eight other platinum complexes. In: Prestayko AW, editor. Cisplatin: current status and new developments. New York: Academic Press, 1980: 193-212
    • (1980) Cisplatin: Current Status and New Developments , pp. 193-212
    • Harrap, K.R.1    Jones, M.2    Wilkinson, C.R.3
  • 43
    • 0024553731 scopus 로고
    • A phase I clinical and pharmacokinetic study of carhoplatin and autologous bone marrow support
    • Shea TC, Flaherty M, Elias A, et al. A Phase I clinical and pharmacokinetic study of carhoplatin and autologous bone marrow support. J Clin Oncol 1989; 7: 651-61
    • (1989) J Clin Oncol , vol.7 , pp. 651-661
    • Shea, T.C.1    Flaherty, M.2    Elias, A.3
  • 44
    • 0026045712 scopus 로고
    • Platinum coordination complexes which circumvent cisplatin resistance
    • Harrap KR, Kelland LR, Jones M, et al. Platinum coordination complexes which circumvent cisplatin resistance. Adv Enzyme Regul 1991; 31: 31-43
    • (1991) Adv Enzyme Regul , vol.31 , pp. 31-43
    • Harrap, K.R.1    Kelland, L.R.2    Jones, M.3
  • 45
    • 0005741390 scopus 로고
    • A novel class of orally active platinum IV coordination complexes which circumvent cisplatin resistance in vitro
    • Harrap KR, Murrer BA, Giandomenico C, et al. A novel class of orally active platinum IV coordination complexes which circumvent cisplatin resistance in vitro. Proc Am Assoc Cancer Res 1991; 32: 428A
    • (1991) Proc Am Assoc Cancer Res , vol.32
    • Harrap, K.R.1    Murrer, B.A.2    Giandomenico, C.3
  • 46
    • 0005702667 scopus 로고
    • New platinum drugs capable of oral administration
    • Harrap KR, Morgan SE, Murrer BA, et al. New platinum drugs capable of oral administration. Ann Oncol 1992; 3 Suppl. 1: 116A
    • (1992) Ann Oncol , vol.3 , Issue.SUPPL. 1
    • Harrap, K.R.1    Morgan, S.E.2    Murrer, B.A.3
  • 48
    • 0342873980 scopus 로고
    • Structure-activity relationships in a series of novel platinum (II) and platinum (IV) ammine/amine complexes evaluated against a panel of human ovarian carcinoma cell lines
    • Kelland LR, Murrer BA, Abel G, et al. Structure-activity relationships in a series of novel platinum (II) and platinum (IV) ammine/amine complexes evaluated against a panel of human ovarian carcinoma cell lines. J Cell Pharmacol 1991; 2: 331-42
    • (1991) J Cell Pharmacol , vol.2 , pp. 331-342
    • Kelland, L.R.1    Murrer, B.A.2    Abel, G.3
  • 49
    • 0026665349 scopus 로고
    • Sensitivity to novel platinum compounds of panels of human lung cancer cell lines with acquired and inherent resistance to cisplatin
    • Twentyman PR, Wright KA, Mistry P, et al. Sensitivity to novel platinum compounds of panels of human lung cancer cell lines with acquired and inherent resistance to cisplatin. Cancer Res 1992; 52: 5674-80
    • (1992) Cancer Res , vol.52 , pp. 5674-5680
    • Twentyman, P.R.1    Wright, K.A.2    Mistry, P.3
  • 50
    • 24844434234 scopus 로고
    • Circumvention of transport-mediated acquired cisplalin resistance in human cancer cell lines by the orally active platinum drug, Bis-acetatoammine dichloro(cyclohexylamine) platinum (IV) (JM216)
    • Kelland LR, Mellish KJ, Abel G, et al. Circumvention of transport-mediated acquired cisplalin resistance in human cancer cell lines by the orally active platinum drug, Bis-acetatoammine dichloro(cyclohexylamine) platinum (IV) (JM216). Proc Am Assoc Cancer Res 1993; 34: 400A
    • (1993) Proc Am Assoc Cancer Res , vol.34
    • Kelland, L.R.1    Mellish, K.J.2    Abel, G.3
  • 51
    • 0027275229 scopus 로고
    • In vitro platinum drug chemosensitivity of human cervical squamous cell carcinoma cell lines with intrinsic and acquired resistance to cisplatin
    • Mellish KJ, Kelland LR, Harrap KR In vitro platinum drug chemosensitivity of human cervical squamous cell carcinoma cell lines with intrinsic and acquired resistance to cisplatin. Br J Cancer 1993; 63: 240-50
    • (1993) Br J Cancer , vol.63 , pp. 240-250
    • Mellish, K.J.1    Kelland, L.R.2    Harrap, K.R.3
  • 52
    • 0027207136 scopus 로고
    • Preclinical antitumor activity of orally administered platinum (IV) complexes
    • Rose WC, Crosswell AR, Schurig JE, et al. Preclinical antitumor activity of orally administered platinum (IV) complexes. Cancer Chermother Pharmacol 1993; 32: 197-203
    • (1993) Cancer Chermother Pharmacol , vol.32 , pp. 197-203
    • Rose, W.C.1    Crosswell, A.R.2    Schurig, J.E.3
  • 53
    • 0029069670 scopus 로고
    • Initiatives with platinum- and quinazoline-hased antitumor molecules - Fourteenth Bruce F. Cain memorial award lecture
    • Harrap KR. Initiatives with platinum- and quinazoline-hased antitumor molecules - Fourteenth Bruce F. Cain Memorial Award Lecture. Cancer Res 1995; 55: 2761-8
    • (1995) Cancer Res , vol.55 , pp. 2761-2768
    • Harrap, K.R.1
  • 55
    • 0026692952 scopus 로고
    • Mechanism-related circumvention of acquired cis-diamminedichloroplatinum(II) resistance using two pairs of human ovarian carcinoma cell lines by ammine/amine platinum(IV) dicarboxylates
    • Kelland LR, Mistry P, Abel G, et al. Mechanism-related circumvention of acquired cis-diamminedichloroplatinum(II) resistance using two pairs of human ovarian carcinoma cell lines by ammine/amine platinum(IV) dicarboxylates. Cancer Res 1992; 52: 3857-64
    • (1992) Cancer Res , vol.52 , pp. 3857-3864
    • Kelland, L.R.1    Mistry, P.2    Abel, G.3
  • 56
    • 0026504232 scopus 로고
    • Ammine/amine platinum(IV) dicarboxylate complexes: A novel class of platinum complex exhibiting selective cytotoxicity to intrinsically cisplatin-resistant human ovarian carcinoma cells lines
    • Kelland LR, Murrer BA, Abel G, et al. Ammine/amine platinum(IV) dicarboxylate complexes: a novel class of platinum complex exhibiting selective cytotoxicity to intrinsically cisplatin-resistant human ovarian carcinoma cells lines. Cancer Res 1992; 52: 822-8
    • (1992) Cancer Res , vol.52 , pp. 822-828
    • Kelland, L.R.1    Murrer, B.A.2    Abel, G.3
  • 57
    • 0028025381 scopus 로고
    • Schedule dependency of orally administered bis-acetato-ammine-dichlorocyclohexytamine-platinum(IV) (JM216) in vivo
    • McKeage MJ, Kelland LR, Boxall FE, et al. Schedule dependency of orally administered bis-acetato-ammine-dichlorocyclohexytamine-platinum(IV) (JM216) in vivo. Cancer Res 1994; 54: 4118-22
    • (1994) Cancer Res , vol.54 , pp. 4118-4122
    • McKeage, M.J.1    Kelland, L.R.2    Boxall, F.E.3
  • 58
    • 0028345821 scopus 로고
    • Preclinical toxicology and tissue platinum distribution of novel oral antitumor platinum complexes: Ammine/amine platinum (IV) dicarboxylates
    • McKeage MJ, Morgan SE, Boxall FE, et al. Preclinical toxicology and tissue platinum distribution of novel oral antitumor platinum complexes: ammine/amine platinum (IV) dicarboxylates. Cancer Chemother Pharmacol 1994; 33: 497-503
    • (1994) Cancer Chemother Pharmacol , vol.33 , pp. 497-503
    • McKeage, M.J.1    Morgan, S.E.2    Boxall, F.E.3
  • 59
    • 0027215201 scopus 로고
    • Lack of nephrotoxicity of oral ammine/amine platinum(IV) dicarboxylate complexes in rodents
    • McKeage MJ, Morgan SE, Boxall FE, et al. Lack of nephrotoxicity of oral ammine/amine platinum(IV) dicarboxylate complexes in rodents. Br J Cancer 1993; 67: 996-1000
    • (1993) Br J Cancer , vol.67 , pp. 996-1000
    • McKeage, M.J.1    Morgan, S.E.2    Boxall, F.E.3
  • 60
    • 0029758018 scopus 로고    scopus 로고
    • Metabolism, protein binding and in vivo activity of the oral platinum drug JM216 and its hiotransformation products
    • Raynaud FI, Boxall FE, Goddard P, et al. Metabolism, protein binding and in vivo activity of the oral platinum drug JM216 and its hiotransformation products. Anticancer Res 1996; 16: 1857-62
    • (1996) Anticancer Res , vol.16 , pp. 1857-1862
    • Raynaud, F.I.1    Boxall, F.E.2    Goddard, P.3
  • 61
    • 0029089517 scopus 로고
    • A phase I and pharmacology study of an oral platinum complex, JM216: Dose-dependent pharmacokinetics with single-dose administration
    • McKeage MJ, Mistry P, Ward J, et al. A Phase I and pharmacology study of an oral platinum complex, JM216: dose-dependent pharmacokinetics with single-dose administration. Cancer Chemother Pharmacol 1995; 36: 451-8
    • (1995) Cancer Chemother Pharmacol , vol.36 , pp. 451-458
    • McKeage, M.J.1    Mistry, P.2    Ward, J.3
  • 62
    • 0030742993 scopus 로고    scopus 로고
    • Phase 1 and pharmacokinetic study of an oral platinum complex given daily for 5 days in patients with cancer
    • McKeage MJ, Raynaud F, Ward J, et al. Phase 1 and pharmacokinetic study of an oral platinum complex given daily for 5 days in patients with cancer. J Clin Oncol 1997; 15: 2691-700
    • (1997) J Clin Oncol , vol.15 , pp. 2691-2700
    • McKeage, M.J.1    Raynaud, F.2    Ward, J.3
  • 63
    • 0031159653 scopus 로고    scopus 로고
    • Phase II trial of the oral platinum complex JM216 in non-small cell lung cancer: An EORTC early clinical studies group investigation
    • Judson I, Cerny T, Epelbaum R, et al. Phase II trial of the oral platinum complex JM216 in non-small cell lung cancer: an EORTC early clinical studies group investigation. Ann Oncol 1997; 8: 604-6
    • (1997) Ann Oncol , vol.8 , pp. 604-606
    • Judson, I.1    Cerny, T.2    Epelbaum, R.3
  • 64
    • 41549110421 scopus 로고    scopus 로고
    • Randomized phase II study of oral JM2 16 versus intravenous cisplatin in non-small cell lung cancer: Preliminary results
    • Fokkema E, Lunenberg J, van Putten JWG, et al. Randomized Phase II study of oral JM2 16 versus intravenous cisplatin in non-small cell lung cancer: preliminary results. Proc Am Soc Clin Oncol 1998; 17: 83A
    • (1998) Proc Am Soc Clin Oncol , vol.17
    • Fokkema, E.1    Lunenberg, J.2    Van Putten, J.W.G.3
  • 65
    • 0010267330 scopus 로고    scopus 로고
    • A phase II study of oral platinum JM-216 as first-line treatment in small cell lung cancer
    • Groen HJM, Smit EF, Bauer J, A Phase II study of oral platinum JM-216 as first-line treatment in small cell lung cancer. Proc Am Soc Clin Oncol 1996; 15: 378A
    • (1996) Proc Am Soc Clin Oncol , vol.15
    • Groen, H.J.M.1    Smit, E.F.2    Bauer, J.3
  • 66
    • 0026580034 scopus 로고
    • Effects of concomitant eisplatin and radiotherapy on inoperable non-small-cell lung cancer
    • Schaake-Koning C, van den Bogaert W, Dalesio O, et al. Effects of concomitant eisplatin and radiotherapy on inoperable non-small-cell lung cancer. N Engl J Med 1992; 326: 524-30
    • (1992) N Engl J Med , vol.326 , pp. 524-530
    • Schaake-Koning, C.1    Van Den Bogaert, W.2    Dalesio, O.3
  • 67
    • 0031446578 scopus 로고    scopus 로고
    • Oral platinum analogue JM216, a radiosensitizer in oxic murine cells
    • van de Vaart PJ, Klaren HM, Hofland I, et al. Oral platinum analogue JM216, a radiosensitizer in oxic murine cells. Int J Radiat Biol 1997; 72: 675-83
    • (1997) Int J Radiat Biol , vol.72 , pp. 675-683
    • Van De Vaart, P.J.1    Klaren, H.M.2    Hofland, I.3
  • 68
    • 0008062845 scopus 로고    scopus 로고
    • Oral JM-216 plus concomitant radiotherapy for patients with advanced malignancies of the chest
    • Hoffman P, Mauer A, Haraf D. et al. Oral JM-216 plus concomitant radiotherapy for patients with advanced malignancies of the chest. Proc Am Soc Clin Oncol 1998; 17: 488A
    • (1998) Proc Am Soc Clin Oncol , vol.17
    • Hoffman, P.1    Mauer, A.2    Haraf D Et, A.3
  • 69
    • 0014895176 scopus 로고
    • Preliminary pharmacologic and clinical evaluation of camptothecin sodium (NSC 100880)
    • Gottlieb JA, Guarino AM, Call JB, et al. Preliminary pharmacologic and clinical evaluation of camptothecin sodium (NSC 100880). Cancer Chemother Rep 1970; 54: 461-70
    • (1970) Cancer Chemother Rep , vol.54 , pp. 461-470
    • Gottlieb, J.A.1    Guarino, A.M.2    Call, J.B.3
  • 70
    • 0015378084 scopus 로고
    • Phase I clinical trial of weekly and daily treatment with camptothecin (NSC 100880): Correlation with preclinical studies
    • Muggia FM, Creaven PJ, Hansen HH, et al. Phase I clinical trial of weekly and daily treatment with camptothecin (NSC 100880): correlation with preclinical studies. Cancer Chemother Rep 1972; 56: 515-21
    • (1972) Cancer Chemother Rep , vol.56 , pp. 515-521
    • Muggia, F.M.1    Creaven, P.J.2    Hansen, H.H.3
  • 71
    • 0029791237 scopus 로고    scopus 로고
    • New promising anticancer agents in development: What comes next?
    • Verweij J. New promising anticancer agents in development: what comes next? Cancer Chemother Pharmacol 1996; 38 Suppl.: S3-S10
    • (1996) Cancer Chemother Pharmacol , vol.38 , Issue.SUPPL.
    • Verweij, J.1
  • 72
    • 0015407723 scopus 로고
    • Plasma camptothecin (NSC-100880) levels during a 5-day course of treatment: Relation to dose and toxicity
    • Creaven PJ, Allen LM, Muggia FM. Plasma camptothecin (NSC-100880) levels during a 5-day course of treatment: relation to dose and toxicity. Cancer Chemother Rep 1972; 56: 573-8
    • (1972) Cancer Chemother Rep , vol.56 , pp. 573-578
    • Creaven, P.J.1    Allen, L.M.2    Muggia, F.M.3
  • 73
    • 0015291595 scopus 로고
    • Phase II study of camptothecin (NSC-100880) in the treatment of advanced gastrointestinal cancer
    • Moertel CCG, Schult AJ, Reitemeier RJ, et al. Phase II study of camptothecin (NSC-100880) in the treatment of advanced gastrointestinal cancer. Cancer Chemother Rev 1972; 56: 95-101
    • (1972) Cancer Chemother Rev , vol.56 , pp. 95-101
    • Moertel, C.C.G.1    Schult, A.J.2    Reitemeier, R.J.3
  • 74
    • 0021506823 scopus 로고
    • Characterisation of size variant of type I DNA topoisomerase isolated from calf thymus
    • Schmitt B, Buhre U, Vosberg HP. Characterisation of size variant of type I DNA topoisomerase isolated from calf thymus. Eur J Biochem 1984; 144: 127-34
    • (1984) Eur J Biochem , vol.144 , pp. 127-134
    • Schmitt, B.1    Buhre, U.2    Vosberg, H.P.3
  • 75
    • 0000482574 scopus 로고
    • Human DNA topoisomerase I is encoded by a single-copy gene that maps to chromosome region 20q 12-13.2
    • Juan C, Hwang J, Liu LF, et al. Human DNA topoisomerase I is encoded by a single-copy gene that maps to chromosome region 20q 12-13.2. Proc Natl Acad Sci USA 1988; 85: 8910-3
    • (1988) Proc Natl Acad Sci USA , vol.85 , pp. 8910-8913
    • Juan, C.1    Hwang, J.2    Liu, L.F.3
  • 76
    • 0015692519 scopus 로고
    • Effects of camptothecin on the breakage and repair of DNA during the cell cycle
    • Horwitz SB, Horwitz MS. Effects of camptothecin on the breakage and repair of DNA during the cell cycle. Cancer Res 1973; 33: 2834-6
    • (1973) Cancer Res , vol.33 , pp. 2834-2836
    • Horwitz, S.B.1    Horwitz, M.S.2
  • 77
    • 0022340594 scopus 로고
    • Camptothecin induces protein-limited DNA breaks via mammalian DNA topoisomerase I
    • Hsiang YH, Hertzberg R, Hecht S, et al. Camptothecin induces protein-limited DNA breaks via mammalian DNA topoisomerase I. J Biol Chem 1985; 260: 14873-8
    • (1985) J Biol Chem , vol.260 , pp. 14873-14878
    • Hsiang, Y.H.1    Hertzberg, R.2    Hecht, S.3
  • 78
    • 0023136543 scopus 로고
    • Relationship between the intracellular effects of camptothecin and the inhibition of DNA topoisomerase I in cultured L1210 cells
    • Mattern MR, Mong SM, Bartus HF, et al. Relationship between the intracellular effects of camptothecin and the inhibition of DNA topoisomerase I in cultured L1210 cells. Cancer Res 1987; 47: 1793-8
    • (1987) Cancer Res , vol.47 , pp. 1793-1798
    • Mattern, M.R.1    Mong, S.M.2    Bartus, H.F.3
  • 79
    • 0024420685 scopus 로고
    • Arrest of replication forks by drug stabilized topoisomerase-I-DNA cleavahle complexes as a mechanism of cell killing by camptothecin
    • Hsiang YH, Lihou MG, Liu LF. Arrest of replication forks by drug stabilized topoisomerase-I-DNA cleavahle complexes as a mechanism of cell killing by camptothecin. Cancer Res 1989; 49: 5077-82
    • (1989) Cancer Res , vol.49 , pp. 5077-5082
    • Hsiang, Y.H.1    Lihou, M.G.2    Liu, L.F.3
  • 80
    • 0024316466 scopus 로고
    • DNA topoisomerasc poisons as antitumor drugs
    • Liu L. DNA topoisomerasc poisons as antitumor drugs. Ann Rev Biochem 1989; 58: 351-74
    • (1989) Ann Rev Biochem , vol.58 , pp. 351-374
    • Liu, L.1
  • 82
    • 0027972726 scopus 로고
    • Topoisomerase 1 inhibitors: Lopotecan and irinotecan
    • Creemers GJ, Lund B, Verweij J. Topoisomerase 1 inhibitors: lopotecan and irinotecan. Cancer Treat Rev 1994; 20: 73-96
    • (1994) Cancer Treat Rev , vol.20 , pp. 73-96
    • Creemers, G.J.1    Lund, B.2    Verweij, J.3
  • 83
    • 0028225686 scopus 로고
    • Comparative activity of oral and parenteral topotecan in murine tumor models: Efficacy of oral topotecan
    • McCabe FL, Johnson RK. Comparative activity of oral and parenteral topotecan in murine tumor models: efficacy of oral topotecan. Cancer Invest 1994; 12: 308-13
    • (1994) Cancer Invest , vol.12 , pp. 308-313
    • McCabe, F.L.1    Johnson, R.K.2
  • 84
    • 0031056424 scopus 로고    scopus 로고
    • Phase I and pharmacologic study of oral topotecan administered twice daily for 21 days to adult patients with solid tumors
    • Creemers GJ, Gerrits CJH, Eckardt JR, et al. Phase I and pharmacologic study of oral topotecan administered twice daily for 21 days to adult patients with solid tumors. J Clin Oncol 1997; 15: 1087-93
    • (1997) J Clin Oncol , vol.15 , pp. 1087-1093
    • Creemers, G.J.1    Gerrits, C.J.H.2    Eckardt, J.R.3
  • 85
    • 0024358188 scopus 로고
    • DNA topoisomerase I-targeted chemotherapy of human colon cancer in xenografts
    • Giovanella BC, Stehlin JS, Wall ME, et al. DNA topoisomerase I-targeted chemotherapy of human colon cancer in xenografts. Science 1989; 246: 1046-8
    • (1989) Science , vol.246 , pp. 1046-1048
    • Giovanella, B.C.1    Stehlin, J.S.2    Wall, M.E.3
  • 86
    • 0026468470 scopus 로고
    • Activity of topotecan, a new topoisomerase I inhibitor, against human tumor colony-forming units in vitro
    • Burris HA, Hanauske AR, Johnson RK, et al. Activity of topotecan, a new topoisomerase I inhibitor, against human tumor colony-forming units in vitro. J Natl Cancer Inst 1992; 84: 1816-20
    • (1992) J Natl Cancer Inst , vol.84 , pp. 1816-1820
    • Burris, H.A.1    Hanauske, A.R.2    Johnson, R.K.3
  • 87
    • 0026487210 scopus 로고
    • Evaluation of 9-dimethylaminomethyl-10-hydroxycamptothecin (topotecan) against xenografts derived from adult and childhood tumors
    • Houghton PJ, Cheshire PJ, Myers L, et al. Evaluation of 9-dimethylaminomethyl-10-hydroxycamptothecin (topotecan) against xenografts derived from adult and childhood tumors. Cancer Chemother Pharmacol 1992; 31: 229-39
    • (1992) Cancer Chemother Pharmacol , vol.31 , pp. 229-239
    • Houghton, P.J.1    Cheshire, P.J.2    Myers, L.3
  • 88
    • 0027454410 scopus 로고
    • Phase I and pharmacokinetics study of topotecan, a new topoisomerase I inhibitor
    • Verweij J, Lund B, Beijnen JH, et al. Phase I and pharmacokinetics study of topotecan, a new topoisomerase I inhibitor. Ann Oncol 1993; 4: 673-8
    • (1993) Ann Oncol , vol.4 , pp. 673-678
    • Verweij, J.1    Lund, B.2    Beijnen, J.H.3
  • 89
    • 0028357995 scopus 로고
    • Phase I trial of low-dose continuous topotecan infusion in patients with cancer: An active and well-tolerated regimen
    • Hochster H, Liebes L, Speyer J, et al. Phase I trial of low-dose continuous topotecan infusion in patients with cancer: an active and well-tolerated regimen. J Clin Oncol 1994; 12: 553-9
    • (1994) J Clin Oncol , vol.12 , pp. 553-559
    • Hochster, H.1    Liebes, L.2    Speyer, J.3
  • 90
    • 0023924786 scopus 로고
    • Identification of mammalian DNA topoisomerase I as an intracellular target of the anticancer drug camptothecin
    • Hsiang YH, Liu LF. Identification of mammalian DNA topoisomerase I as an intracellular target of the anticancer drug camptothecin. Cancer Res 1988; 48: 1722-6
    • (1988) Cancer Res , vol.48 , pp. 1722-1726
    • Hsiang, Y.H.1    Liu, L.F.2
  • 91
    • 0011636075 scopus 로고
    • Phase II study of topotecan in refractory and sensitive small cell lung cancer
    • Ardizzoni A, Hansen HH, Dombernowsky P, et al. Phase II study of topotecan in refractory and sensitive small cell lung cancer. Eur J Cancer 1995; 31A Suppl. 5: S19
    • (1995) Eur J Cancer , vol.31 A , Issue.SUPPL. 5
    • Ardizzoni, A.1    Hansen, H.H.2    Dombernowsky, P.3
  • 92
    • 0030482311 scopus 로고    scopus 로고
    • Clinical studies of topotecan
    • Broom C. Clinical studies of topotecan. Ann N Y Acad Sci 1996; 803: 264-71
    • (1996) Ann N Y Acad Sci , vol.803 , pp. 264-271
    • Broom, C.1
  • 93
    • 0026537874 scopus 로고
    • Phase I and pharmacologic study of topotecan: A novel topoisomerase I inhibitor
    • Rowinsky EK, Grochow LB, Hendricks CB, et al. Phase I and pharmacologic study of topotecan: a novel topoisomerase I inhibitor. J Clin Oncol 1992; 10: 647-56
    • (1992) J Clin Oncol , vol.10 , pp. 647-656
    • Rowinsky, E.K.1    Grochow, L.B.2    Hendricks, C.B.3
  • 94
    • 0026697849 scopus 로고
    • A phase I clinical and pharmacokinetic study of the topoisomerase I inhibitor, topotecan (SK&F 104864), given as an intravenous bolus every 21 days
    • Wall JA, Burris HA, Von Hoff DD, et al. A Phase I clinical and pharmacokinetic study of the topoisomerase I inhibitor, topotecan (SK&F 104864), given as an intravenous bolus every 21 days. Anticancer Drugs 1992; 3: 337-45
    • (1992) Anticancer Drugs , vol.3 , pp. 337-345
    • Wall, J.A.1    Burris, H.A.2    Von Hoff, D.D.3
  • 95
    • 0000943872 scopus 로고
    • Phase II study of topotecan in extensive stage small cell lung cancer
    • Schiller JH, Kim K, Johnson, D. Phase II study of topotecan in extensive stage small cell lung cancer. Proc Am Soc Clin Oncol 1994; 13: 330A
    • (1994) Proc Am Soc Clin Oncol , vol.13
    • Schiller, J.H.1    Kim, K.2
  • 96
    • 0007704867 scopus 로고    scopus 로고
    • Topotecan versus cyclophosphamide, doxorubicin and vincristine for the treatment of patients with recurrent small cell lung cancer, a phase II study
    • Schiller J, Von Pawel J, Shepherd F, et al. Topotecan versus cyclophosphamide, doxorubicin and vincristine for the treatment of patients with recurrent small cell lung cancer, a Phase II study. Proc Am Soc Clin Oncol 1998; 17: 456A
    • (1998) Proc Am Soc Clin Oncol , vol.17
    • Schiller, J.1    Von Pawel, J.2    Shepherd, F.3
  • 97
    • 0029973829 scopus 로고    scopus 로고
    • Bioavailability and pharmacokinetics of oral topotecan: A new topoisomerase I inhibitor
    • Schellens JHM, Creemers GJ, Beijnen JH, et al. Bioavailability and pharmacokinetics of oral topotecan: a new topoisomerase I inhibitor. Br J Cancer 1996; 73: 1268-71
    • (1996) Br J Cancer , vol.73 , pp. 1268-1271
    • Schellens, J.H.M.1    Creemers, G.J.2    Beijnen, J.H.3
  • 99
    • 13344250486 scopus 로고    scopus 로고
    • Effects of novel retinoid x receptor-selective ligands on myeloid leukemic differentiation and proliferation in vitro
    • Kizaki M, Dawson MI, Heyman R, et al. Effects of novel retinoid X receptor-selective ligands on myeloid leukemic differentiation and proliferation in vitro. Blood 1996; 87: 1977-84
    • (1996) Blood , vol.87 , pp. 1977-1984
    • Kizaki, M.1    Dawson, M.I.2    Heyman, R.3
  • 100
    • 0028362475 scopus 로고
    • Novel retinoic acid, 9-cis retinoic acid, in combination with all-Irans retinoic acid is an effective inducer of differentiation of retinoic acid-resistant HL-60 cells
    • Kizaki M, Nakajima H, Mori S, et al. Novel retinoic acid, 9-cis retinoic acid, in combination with all-Irans retinoic acid is an effective inducer of differentiation of retinoic acid-resistant HL-60 cells. Blood 1994; 83: 3289-97
    • (1994) Blood , vol.83 , pp. 3289-3297
    • Kizaki, M.1    Nakajima, H.2    Mori, S.3
  • 101
    • 0031024325 scopus 로고    scopus 로고
    • Initial clinical trial of a selective retinoid X receptor ligand, LGD1069
    • Miller VA, Benedetti FM, Rigas JR. et al. Initial clinical trial of a selective retinoid X receptor ligand, LGD1069. J Clin Oncol 1997; 15: 790-5
    • (1997) J Clin Oncol , vol.15 , pp. 790-795
    • Miller, V.A.1    Benedetti, F.M.2    Rigas, J.R.3
  • 102
    • 0028087742 scopus 로고
    • Synthesis and structure-activity relationships of novel retinoid X receptor-selective retinoids
    • Boehm MF, Zhang L, Badea BA, et al. Synthesis and structure-activity relationships of novel retinoid X receptor-selective retinoids. J Med Chem 1994; 37: 2930-41
    • (1994) J Med Chem , vol.37 , pp. 2930-2941
    • Boehm, M.F.1    Zhang, L.2    Badea, B.A.3
  • 103
    • 0029097177 scopus 로고
    • Design and synthesis of potent retinoid X receptor selective ligands that induce apoptosis in leukemia cells
    • Boehm MF, Zhang L, Zhi L, et al. Design and synthesis of potent retinoid X receptor selective ligands that induce apoptosis in leukemia cells. J Med Chem 1995; 38: 3146-55
    • (1995) J Med Chem , vol.38 , pp. 3146-3155
    • Boehm, M.F.1    Zhang, L.2    Zhi, L.3
  • 104
    • 0026536522 scopus 로고
    • Retinoid X receptor is an auxiliary protein for thyroid hormone and retinoic acid receptors
    • Zhang XK, Hoffmann B, Tran PBV, et al. Retinoid X receptor is an auxiliary protein for thyroid hormone and retinoic acid receptors. Nature 1992; 355: 441-6
    • (1992) Nature , vol.355 , pp. 441-446
    • Zhang, X.K.1    Hoffmann, B.2    Tran, P.B.V.3
  • 105
    • 0026705751 scopus 로고
    • Convergence of 9-cis retinoic acid and peroxisome proliferator signalling pathways through heterodimer formation of their receptors
    • Kliewer SA, Umesono K, Noonan DJ, et al. Convergence of 9-cis retinoic acid and peroxisome proliferator signalling pathways through heterodimer formation of their receptors. Nature 1992; 358: 771-4
    • (1992) Nature , vol.358 , pp. 771-774
    • Kliewer, S.A.1    Umesono, K.2    Noonan, D.J.3
  • 106
    • 0026742534 scopus 로고
    • Multiplicity generates diversity in the retinoic acid signalling pathways
    • Leid M, Kastner P, Chambon P. Multiplicity generates diversity in the retinoic acid signalling pathways. Trends Biochem Sci 1992; 17: 427-33
    • (1992) Trends Biochem Sci , vol.17 , pp. 427-433
    • Leid, M.1    Kastner, P.2    Chambon, P.3
  • 107
    • 0029063607 scopus 로고
    • Activation of retinoid X receptors induces apoptosis in HL-60 cell lines
    • Nagy L, Thomazy VA, Shipley GL, et al. Activation of retinoid X receptors induces apoptosis in HL-60 cell lines. Mol Cell Biol 1995; 15: 3540-51
    • (1995) Mol Cell Biol , vol.15 , pp. 3540-3551
    • Nagy, L.1    Thomazy, V.A.2    Shipley, G.L.3
  • 109
    • 0018414126 scopus 로고
    • Prolonged remissions of cystic and conglobate acne with 13-cis-retinoic acid
    • Peck GL, Olsen TG, Yoder KW. Prolonged remissions of cystic and conglobate acne with 13-cis-retinoic acid. N Engl J Med 1979; 300: 329-33
    • (1979) N Engl J Med , vol.300 , pp. 329-333
    • Peck, G.L.1    Olsen, T.G.2    Yoder, K.W.3
  • 110
    • 0020086058 scopus 로고
    • Treatment of ichthyosis with isotretinoin
    • Baden HP, Buxman MM, Weinstein GD, et al. Treatment of ichthyosis with isotretinoin. J Am Acad Dermatol 1982; 6 Suppl. 2: 716-20
    • (1982) J Am Acad Dermatol , vol.6 , Issue.SUPPL. 2 , pp. 716-720
    • Baden, H.P.1    Buxman, M.M.2    Weinstein, G.D.3
  • 111
    • 0020035723 scopus 로고
    • Isotretinoid versus placebo in the treatment of cystic acne. A randomized double-blind study
    • Peck GL, Olsen TG, Butkus D, et al. Isotretinoid versus placebo in the treatment of cystic acne. A randomized double-blind study. J Am Acad Dermatol 1982; 6: 735-45
    • (1982) J Am Acad Dermatol , vol.6 , pp. 735-745
    • Peck, G.L.1    Olsen, T.G.2    Butkus, D.3
  • 112
    • 0026583597 scopus 로고
    • 13-cis-Retinoic acid and Interferon α-2a: Effective combination therapy for advanced squamous cell carcinoma of the skin
    • Lippman SM, Parkinson DR, Itri LM. et al. 13-cis-Retinoic acid and Interferon α-2a: effective combination therapy for advanced squamous cell carcinoma of the skin. J Natl Cancer Inst 1992; 84: 235-41
    • (1992) J Natl Cancer Inst , vol.84 , pp. 235-241
    • Lippman, S.M.1    Parkinson, D.R.2    Itri, L.M.3
  • 113
    • 0026600705 scopus 로고
    • 13-cis-Retinoic acid plus interferon α-2a: Highly active systemic therapy for squamous cell carcinoma of the cervix
    • Lippman SM, Kavanagh JJ, Paredes Espinoza M, et al. 13-cis-Retinoic acid plus interferon α-2a: highly active systemic therapy for squamous cell carcinoma of the cervix. J Natl Cancer Inst 1992; 84: 241-5
    • (1992) J Natl Cancer Inst , vol.84 , pp. 241-245
    • Lippman, S.M.1    Kavanagh, J.J.2    Paredes Espinoza, M.3
  • 114
    • 0027518643 scopus 로고
    • Regression of oral leukoplakia with alpha-tocopherol: A community clinical oncology program chemotherapy study
    • Benner SE, Winn RJ, Lippman SM, et al. Regression of oral leukoplakia with alpha-tocopherol: a community clinical oncology program chemotherapy study. J Natl Cancer Inst 1993; 85: 44-7
    • (1993) J Natl Cancer Inst , vol.85 , pp. 44-47
    • Benner, S.E.1    Winn, R.J.2    Lippman, S.M.3
  • 115
    • 0027938555 scopus 로고
    • Retinoid chemoprevention of second primary tumors
    • Benner SE, Lippman SM, Hong WK. Retinoid chemoprevention of second primary tumors. Semin Hematol 1994; 31 Suppl. 5: 26-30
    • (1994) Semin Hematol , vol.31 , Issue.SUPPL. 5 , pp. 26-30
    • Benner, S.E.1    Lippman, S.M.2    Hong, W.K.3
  • 116
    • 0020506009 scopus 로고
    • Induction of differentiation of human acute myelogenous leukemia cells: Therapeutic implications
    • Koeffler P. Induction of differentiation of human acute myelogenous leukemia cells: therapeutic implications. Blood 1983; 62: 709-21
    • (1983) Blood , vol.62 , pp. 709-721
    • Koeffler, P.1
  • 117
    • 0020076632 scopus 로고
    • Retinoic acid. Inhibition of the clonal growth of human myeloid leukemia cells
    • Douer D, Koeffler P. Retinoic acid. Inhibition of the clonal growth of human myeloid leukemia cells. J Clin Invest 1982; 69: 277-83
    • (1982) J Clin Invest , vol.69 , pp. 277-283
    • Douer, D.1    Koeffler, P.2
  • 118
    • 0025683226 scopus 로고
    • Inhibition of tumor cell growth by relinoids
    • Lotan R, Lotan D, Sacks PG. Inhibition of tumor cell growth by relinoids. Methods Enzymol 1990; 190: 100-10
    • (1990) Methods Enzymol , vol.190 , pp. 100-110
    • Lotan, R.1    Lotan, D.2    Sacks, P.G.3
  • 119
    • 0023752982 scopus 로고
    • Use of all-trans retinoic acid in the treatment of acute promyelocytic leukemia
    • Huang ME, Ye YC, Chen SR, et al. Use of all-trans retinoic acid in the treatment of acute promyelocytic leukemia. Blood 1988; 72: 567-72
    • (1988) Blood , vol.72 , pp. 567-572
    • Huang, M.E.1    Ye, Y.C.2    Chen, S.R.3
  • 120
    • 0025201879 scopus 로고
    • All-trans retinoic acid as a differentiation therapy for acute promyelocytic leukemia. 1. Clinical results
    • Castaigne S, Chomienne C, Daniel MT, et al. All-trans retinoic acid as a differentiation therapy for acute promyelocytic leukemia. 1. Clinical results. Blood 1990; 76: 1704-9
    • (1990) Blood , vol.76 , pp. 1704-1709
    • Castaigne, S.1    Chomienne, C.2    Daniel, M.T.3
  • 121
    • 0026040363 scopus 로고
    • A clinical and experimental study on all-trans retinoic acid-treated acute promyelocytic patients
    • Chen ZX, Xue YQ, Zhang R, et al. A clinical and experimental study on all-trans retinoic acid-treated acute promyelocytic patients. Blood 1991; 78: 1413-9
    • (1991) Blood , vol.78 , pp. 1413-1419
    • Chen, Z.X.1    Xue, Y.Q.2    Zhang, R.3
  • 122
    • 0029050432 scopus 로고
    • 9-cis retinoic acid induces complete remission but does not reverse clinically acquired retinoid resistance in acute promyelocytic leukemia
    • Miller Jr WH, Jakubowski A, Tong WP, et al. 9-cis retinoic acid induces complete remission but does not reverse clinically acquired retinoid resistance in acute promyelocytic leukemia. Blood 1995; 85: 3021-7
    • (1995) Blood , vol.85 , pp. 3021-3027
    • Miller W.H., Jr.1    Jakubowski, A.2    Tong, W.P.3
  • 123
    • 0027332981 scopus 로고
    • N-(4-hydroxyphenyl)retinamide induces apoptosis of malignant hemopoietic cell lines including those unresponsive to retinoic acid
    • Delia D, Aiello A, Lombardi L, et al. N-(4-hydroxyphenyl)retinamide induces apoptosis of malignant hemopoietic cell lines including those unresponsive to retinoic acid. Cancer Res 1993; 53: 6036-41
    • (1993) Cancer Res , vol.53 , pp. 6036-6041
    • Delia, D.1    Aiello, A.2    Lombardi, L.3
  • 124
    • 0030071518 scopus 로고    scopus 로고
    • Activation of retinoid receptors RAR-a and RXR-a induces differentiation and apoptosis, respectively, in HL-60 cells
    • Mehta K, McQueen T, Neamati N. Activation of retinoid receptors RAR-a and RXR-a induces differentiation and apoptosis, respectively, in HL-60 cells. Cell Growth Differ 1996; 7: 179-86
    • (1996) Cell Growth Differ , vol.7 , pp. 179-186
    • Mehta, K.1    McQueen, T.2    Neamati, N.3
  • 125
    • 0030846066 scopus 로고    scopus 로고
    • Oxidative metabolism of a retinoid and rapid phase II metabolite identification by mass spectrometry
    • Shirley MA, Wheelan P, Howell SR, et al. Oxidative metabolism of a retinoid and rapid phase II metabolite identification by mass spectrometry. Drug Metab Dispos 1997; 25: 1144-9
    • (1997) Drug Metab Dispos , vol.25 , pp. 1144-1149
    • Shirley, M.A.1    Wheelan, P.2    Howell, S.R.3
  • 126
    • 0029731340 scopus 로고    scopus 로고
    • Chemoprevention of mammary carcinoma by LGD1069 (Targretin): An RXR-selective ligand
    • Gottardis MM, Bischoff ED, Shirley MA, et al. Chemoprevention of mammary carcinoma by LGD1069 (Targretin): an RXR-selective ligand. Cancer Res 1996; 56: 5566-70
    • (1996) Cancer Res , vol.56 , pp. 5566-5570
    • Gottardis, M.M.1    Bischoff, E.D.2    Shirley, M.A.3
  • 127
    • 0032006028 scopus 로고    scopus 로고
    • Beyond tamoxifen: The retinoid X receptor-selective ligand LGD1069 (Targretin) causes complete regression of mammary carcinoma
    • Bischoff ED, Gottardis MM, Moon TE, et al. Beyond tamoxifen: the retinoid X receptor-selective ligand LGD1069 (Targretin) causes complete regression of mammary carcinoma. Cancer Res 1998; 58: 479-84
    • (1998) Cancer Res , vol.58 , pp. 479-484
    • Bischoff, E.D.1    Gottardis, M.M.2    Moon, T.E.3
  • 128
    • 0019508833 scopus 로고
    • Purification of rabbit bone inhibitor of collagenase
    • Cawston TE, Galloway WA, Mercer E, et al. Purification of rabbit bone inhibitor of collagenase. Biochem J 1981; 195: 159-65
    • (1981) Biochem J , vol.195 , pp. 159-165
    • Cawston, T.E.1    Galloway, W.A.2    Mercer, E.3
  • 129
    • 0021325829 scopus 로고
    • Extracts of human articular cartilage contain an inhibitor of tissue metalloproteinases
    • Dean DD, Woessner Jr JF. Extracts of human articular cartilage contain an inhibitor of tissue metalloproteinases. Biochem J 1984; 218: 277-80
    • (1984) Biochem J , vol.218 , pp. 277-280
    • Dean, D.D.1    Woessner J.F., Jr.2
  • 130
    • 0025317277 scopus 로고
    • The role of stromelysin in the cartilage destruction that accompanies inflammatory arthritis
    • Hasty KA, Reife RA, Kang AH, et al. The role of stromelysin in the cartilage destruction that accompanies inflammatory arthritis. Arthritis Rheum 1990; 33: 388-97
    • (1990) Arthritis Rheum , vol.33 , pp. 388-397
    • Hasty, K.A.1    Reife, R.A.2    Kang, A.H.3
  • 131
    • 0000278013 scopus 로고
    • Matrix inetalloproteinase inhibitors: A new class of anticancer agent
    • Brown PD. Matrix inetalloproteinase inhibitors: a new class of anticancer agent. Curr Opin Invest Drugs 1993; 2: 617-26
    • (1993) Curr Opin Invest Drugs , vol.2 , pp. 617-626
    • Brown, P.D.1
  • 132
    • 0001419988 scopus 로고    scopus 로고
    • Bay 12-9566, a novel, biphenyl matrix metalloproteinase inhibitor, demonstrates anti-invasive and anti-angiogenic properties
    • Hibner B, Card A, Flynn C, et al. Bay 12-9566, a novel, biphenyl matrix metalloproteinase inhibitor, demonstrates anti-invasive and anti-angiogenic properties. Proc Am Assoc Cancer Res 1998; 39: 302A
    • (1998) Proc Am Assoc Cancer Res , vol.39
    • Hibner, B.1    Card, A.2    Flynn, C.3
  • 133
    • 0001419989 scopus 로고    scopus 로고
    • Activity of the biphenyl matrix metalloproteinase inhibitor BAY 12-9566 in murine in vivo models
    • Bull C, Flynn C, Eberwein D, et al. Activity of the biphenyl matrix metalloproteinase inhibitor BAY 12-9566 in murine in vivo models. Proc Am Assoc Cancer Res 1998; 39: 302A
    • (1998) Proc Am Assoc Cancer Res , vol.39
    • Bull, C.1    Flynn, C.2    Eberwein, D.3
  • 134
    • 0000823543 scopus 로고    scopus 로고
    • Anti-metastatic activity of BAY 12-9566 in a human colon carcinoma HCT 116 orthotopic model
    • Flynn C, Bull C, Eberwein D, et al. Anti-metastatic activity of BAY 12-9566 in a human colon carcinoma HCT 116 orthotopic model. Proc Am Assoc Cancer Res 1998; 39: 301A
    • (1998) Proc Am Assoc Cancer Res , vol.39
    • Flynn, C.1    Bull, C.2    Eberwein, D.3
  • 135
    • 0001719456 scopus 로고    scopus 로고
    • Comparative pharmacokinetics of BAY 12-9566, a metalloproteinase inhibitor, in healthy volunteers and cancer patients
    • Shah A, Sundaresan P, Humphrey R, et al. Comparative pharmacokinetics of BAY 12-9566, a metalloproteinase inhibitor, in healthy volunteers and cancer patients. Proc Am Assoc Cancer Res 1998; 39: 521A
    • (1998) Proc Am Assoc Cancer Res , vol.39
    • Shah, A.1    Sundaresan, P.2    Humphrey, R.3
  • 136
    • 0000550788 scopus 로고    scopus 로고
    • Pharmacokinetics of BAY12-9566: Early results of a Canadian phase I dose escalation study in cancer patients
    • Hirte H, Goel R, Major P, et al. Pharmacokinetics of BAY12-9566: early results of a Canadian Phase I dose escalation study in cancer patients. Proc Am Assoc Cancer Res 1998; 39: 364A
    • (1998) Proc Am Assoc Cancer Res , vol.39
    • Hirte, H.1    Goel, R.2    Major, P.3
  • 137
    • 0033512761 scopus 로고    scopus 로고
    • The role of tegafur.uracil in pulmonary malignancy
    • Langer CJ. The role of tegafur.uracil in pulmonary malignancy. Drugs 1999; 58 Suppl. 3: 71-5
    • (1999) Drugs , vol.58 , Issue.SUPPL. 3 , pp. 71-75
    • Langer, C.J.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.