-
2
-
-
0028843552
-
Chemotherapy in non-small cell lung cancer: A meta-analysis using updated data on individual patients from 52 randomised clinical trials. Non-small cell lung cancer collaborative group
-
Anonymous. Chemotherapy in non-small cell lung cancer: a meta-analysis using updated data on individual patients from 52 randomised clinical trials. Non-small Cell Lung Cancer Collaborative Group. BMJ 1995; 311: 899-909
-
(1995)
BMJ
, vol.311
, pp. 899-909
-
-
-
3
-
-
0001773102
-
Mitomycin, ifosfamide and cisplatin in non-small cell lung cancer: 2. Results of a randomised trial in patients with extensive disease
-
Cullen MH, Woodroffe CM, Billingham L.J, et al. Mitomycin, ifosfamide and cisplatin in non-small cell lung cancer: 2. Results of a randomised trial in patients with extensive disease-Lung Cancer 1997; 18 Suppl. 1: 5
-
(1997)
Lung Cancer
, vol.18
, Issue.SUPPL. 1
, pp. 5
-
-
Cullen, M.H.1
Woodroffe, C.M.2
Billingham, L.J.3
-
4
-
-
0020854087
-
On the receiving end-II. Linear analogue self-assessment (LASA) in evaluation of aspects of the quality of life of cancer patients receiving therapy
-
Coates A, Dillenbeck CF, McNeil DR, et al. On the receiving end-II. Linear analogue self-assessment (LASA) in evaluation of aspects of the quality of life of cancer patients receiving therapy. Eur J Cancer Clin Oncol 1983; 19: 1633-7
-
(1983)
Eur J Cancer Clin Oncol
, vol.19
, pp. 1633-1637
-
-
Coates, A.1
Dillenbeck, C.F.2
McNeil, D.R.3
-
5
-
-
0020699588
-
On the receiving end-patient perception of the side-effects of cancer chemotherapy
-
Coates A, Abraham S, Kaye SB, et al. On the receiving end-patient perception of the side-effects of cancer chemotherapy. Eur J Cancer Clin Oncol 1983; 19: 203-8
-
(1983)
Eur J Cancer Clin Oncol
, vol.19
, pp. 203-208
-
-
Coates, A.1
Abraham, S.2
Kaye, S.B.3
-
6
-
-
0024337159
-
Biochemical effects of Navelbine® on tubulin and associated proteins
-
Fellous A, Ohayon R, Vacassin T, et al. Biochemical effects of Navelbine® on tubulin and associated proteins. Semin Oncol 1989; 16 Suppl. 4:9-14
-
(1989)
Semin Oncol
, vol.16
, Issue.SUPPL. 4
, pp. 9-14
-
-
Fellous, A.1
Ohayon, R.2
Vacassin, T.3
-
7
-
-
0024474775
-
The synthesis of Navelbine® - Prototype of a new series of vinblastine derivatives
-
Potier P. The synthesis of Navelbine® - prototype of a new series of vinblastine derivatives. Semin Oncol 1989; 16 Suppl. 4: 2-4
-
(1989)
Semin Oncol
, vol.16
, Issue.SUPPL. 4
, pp. 2-4
-
-
Potier, P.1
-
8
-
-
0024379852
-
In situ analysis of the action of Navelbine on various types of microtubules using immunofluorescence
-
Binet S, Fellous A, Lataste H, et al. In situ analysis of the action of Navelbine on various types of microtubules using immunofluorescence. Semin Oncol 1989; 16 Suppl. 4: 5-8
-
(1989)
Semin Oncol
, vol.16
, Issue.SUPPL. 4
, pp. 5-8
-
-
Binet, S.1
Fellous, A.2
Lataste, H.3
-
9
-
-
0025160828
-
Immunofluorescence study of the action of navelbine, vincristine and vinblastine on mitotic and axonal microtubules
-
Binet S, Chaineau E, Fellous A, et al. Immunofluorescence study of the action of navelbine, vincristine and vinblastine on mitotic and axonal microtubules. Int J Cancer 1990; 46: 262-6
-
(1990)
Int J Cancer
, vol.46
, pp. 262-266
-
-
Binet, S.1
Chaineau, E.2
Fellous, A.3
-
10
-
-
0024364114
-
Pharmacokinetics and metabolism of Navelbine®
-
Krikorian A, Rahmani R, Bromet M, et al. Pharmacokinetics and metabolism of Navelbine®. Semin Oncol 1989; 16 Suppl. 4:21-5
-
(1989)
Semin Oncol
, vol.16
, Issue.SUPPL. 4
, pp. 21-25
-
-
Krikorian, A.1
Rahmani, R.2
Bromet, M.3
-
11
-
-
0019124123
-
Comparative pharmacokinetics of vindesine, vincristine, and vinblastine in patients with cancer
-
Nelson R, Dyke RW, Root MA. Comparative pharmacokinetics of vindesine, vincristine, and vinblastine in patients with cancer. Cancer Treat Rev 1980; 7 Suppl. 1: 17-24
-
(1980)
Cancer Treat Rev
, vol.7
, Issue.SUPPL. 1
, pp. 17-24
-
-
Nelson, R.1
Dyke, R.W.2
Root, M.A.3
-
12
-
-
0020027577
-
The comparative clinical pharmacology and pharmacokinetics of vindesine, vincristine, and vinblastine in human patients with cancer
-
Nelson R. The comparative clinical pharmacology and pharmacokinetics of vindesine, vincristine, and vinblastine in human patients with cancer. Med Pediatr Oncol 1982; 10: 115-27
-
(1982)
Med Pediatr Oncol
, vol.10
, pp. 115-127
-
-
Nelson, R.1
-
13
-
-
0027435310
-
Pulmonary distribution of vinorelbine in patients with non-small cell lung cancer
-
Leveque D, Quoix E, Dumont P, et al. Pulmonary distribution of vinorelbine in patients with non-small cell lung cancer. Cancer Chemother Pharmacol 1993; 33: 176-8
-
(1993)
Cancer Chemother Pharmacol
, vol.33
, pp. 176-178
-
-
Leveque, D.1
Quoix, E.2
Dumont, P.3
-
14
-
-
0028154069
-
Randomized study of vinorelbine and cisplatin versus vindesinc and cisplatin versus vinorelbine alone in advanced non-small-cell lung cancer: Results of a european multicenter trial including 612 patients
-
Le Chevalier T, Brisgand D, Douillard JY, et al. Randomized study of vinorelbine and cisplatin versus vindesinc and cisplatin versus vinorelbine alone in advanced non-small-cell lung cancer: results of a European multicenter trial including 612 patients. J Clin Oncol 1994; 12: 360-7
-
(1994)
J Clin Oncol
, vol.12
, pp. 360-367
-
-
Le Chevalier, T.1
Brisgand, D.2
Douillard, J.Y.3
-
15
-
-
0343744663
-
Vincaleukoblastine III. Clinical trial with the oral preparation
-
Hodes M, Rohn R, Bond W. Vincaleukoblastine III. Clinical trial with the oral preparation. Cancer Chemother Rep 1961, 14: 129-38
-
(1961)
Cancer Chemother Rep
, vol.14
, pp. 129-138
-
-
Hodes, M.1
Rohn, R.2
Bond, W.3
-
16
-
-
0343744664
-
Oral administration of vinblastine sulfate (NSC-49842) to cancer patients
-
Korst DR, Nixon JC. Oral administration of vinblastine sulfate (NSC-49842) to cancer patients. Cancer Chemother Rep 1965; 45: 53-6
-
(1965)
Cancer Chemother Rep
, vol.45
, pp. 53-56
-
-
Korst, D.R.1
Nixon, J.C.2
-
18
-
-
0014115486
-
The response of Hodgkin's disease to treatment with oral vinblastine sulfate
-
Wilson HE, Louis J. The response of Hodgkin's disease to treatment with oral vinblastine sulfate. Ann Intern Med 1967; 67: 303-8
-
(1967)
Ann Intern Med
, vol.67
, pp. 303-308
-
-
Wilson, H.E.1
Louis, J.2
-
19
-
-
0029843025
-
Clinical pharmacokinetics of vinorelbine
-
Leveque D, Jehl F. Clinical pharmacokinetics of vinorelbine. Clin Pharmacokinet 1996; 31: 184-97
-
(1996)
Clin Pharmacokinet
, vol.31
, pp. 184-197
-
-
Leveque, D.1
Jehl, F.2
-
20
-
-
0025949951
-
Pharmacokinetics of Navelbine after oral administration in cancer patients
-
Zhou XJ, Bore P, Monjanel S, et al. Pharmacokinetics of Navelbine after oral administration in cancer patients. Cancer Chemother Pharmacol 1991; 29: 66-70
-
(1991)
Cancer Chemother Pharmacol
, vol.29
, pp. 66-70
-
-
Zhou, X.J.1
Bore, P.2
Monjanel, S.3
-
21
-
-
0027987481
-
Pharmacokinetic, bioavailability, and feasibility study of oral vinorelbine in patients with solid tumors
-
Rowinsky EK, Noe DA, Trump DL, et al. Pharmacokinetic, bioavailability, and feasibility study of oral vinorelbine in patients with solid tumors. J Clin Oncol 1994; 12: 1754-63
-
(1994)
J Clin Oncol
, vol.12
, pp. 1754-1763
-
-
Rowinsky, E.K.1
Noe, D.A.2
Trump, D.L.3
-
22
-
-
0024591753
-
Pharmacokinetics of a new anticancer drug, navelbine, in patients
-
Bore P, Rahmani R, Van Cantfort J, et al. Pharmacokinetics of a new anticancer drug, navelbine, in patients. Cancer Chemother Pharmacol 1989; 23: 247-51
-
(1989)
Cancer Chemother Pharmacol
, vol.23
, pp. 247-251
-
-
Bore, P.1
Rahmani, R.2
Van Cantfort, J.3
-
23
-
-
0025904173
-
Pharmacokinetic and preliminary metabolic fate of navelbine in humans as determined by high performance liquid chromatography
-
Jehl F, Quoix E, Leveque D, et al. Pharmacokinetic and preliminary metabolic fate of navelbine in humans as determined by high performance liquid Chromatography. Cancer Res 1991; 51: 2073-6
-
(1991)
Cancer Res
, vol.51
, pp. 2073-2076
-
-
Jehl, F.1
Quoix, E.2
Leveque, D.3
-
24
-
-
0027996614
-
The clinical pharmacokinetics of vinorelbine (navelbine)
-
Wargin WA, Lucas VS. The clinical pharmacokinetics of vinorelbine (navelbine). Semin Oncol 1994; 21 Suppl. 10: 21-7
-
(1994)
Semin Oncol
, vol.21
, Issue.SUPPL. 10
, pp. 21-27
-
-
Wargin, W.A.1
Lucas, V.S.2
-
25
-
-
0007769152
-
Phase I trial of escalating doses of orally administered Navelbine. Pt II. Clinical results
-
Favre R, Delgado M, Besenval M. Phase I trial of escalating doses of orally administered Navelbine. Pt II. Clinical results. Proc Am Soc Clin Oncol 1989; 8: 64A
-
(1989)
Proc Am Soc Clin Oncol
, vol.8
-
-
Favre, R.1
Delgado, M.2
Besenval, M.3
-
26
-
-
0007812281
-
Phase I trial of escalating doses of orally administered Navelbine. Pt I. Pharmacokinetics
-
Rahmani R, Bore P, Cano JP. Phase I trial of escalating doses of orally administered Navelbine. Pt I. Pharmacokinetics. Proc Am Soc Clin Oncol 1989; 8: 74A
-
(1989)
Proc Am Soc Clin Oncol
, vol.8
-
-
Rahmani, R.1
Bore, P.2
Cano, J.P.3
-
27
-
-
0026199875
-
3H]navelbine in patients: Comparative pharmacokinetics using radioactive and radioimmunologic determination methods
-
3H]Navelbine in patients: comparative pharmacokinetics using radioactive and radioimmunologic determination methods. Anticancer Drugs 1991; 2: 405-10
-
(1991)
Anticancer Drugs
, vol.2
, pp. 405-410
-
-
Rahmani, R.1
Zhou, X.J.2
Bore, P.3
-
28
-
-
84912874846
-
Clinical results of a study of the absolute bioavailability and pharmacokinetics of weekly vinorelbine liquid-filled soft gelatin capsules at full therapeutic doses in patients with solid tumors
-
Lucas S, Donehower R, Rowinsky E. Clinical results of a study of the absolute bioavailability and pharmacokinetics of weekly vinorelbine liquid-filled soft gelatin capsules at full therapeutic doses in patients with solid tumors. Proc Am Soc Clin Oncol 1992; 11: 287A
-
(1992)
Proc Am Soc Clin Oncol
, vol.11
-
-
Lucas, S.1
Donehower, R.2
Rowinsky, E.3
-
29
-
-
0028064823
-
Relative bioavailability of two oral formulations of navelbine in cancer patients
-
Zhou XJ, Zhou-Pan XR, Favre R, et al. Relative bioavailability of two oral formulations of navelbine in cancer patients. Biopharm Drug Dispos 1994; 15: 577-86
-
(1994)
Biopharm Drug Dispos
, vol.15
, pp. 577-586
-
-
Zhou, X.J.1
Zhou-Pan, X.R.2
Favre, R.3
-
30
-
-
0028931164
-
Multicenter phase Il study of weekly oral vinorelbine fur stage IV non-small-cell lung cancer
-
Vokes EE, Rosenberg RK, Jahanzeb M, et al. Multicenter phase Il study of weekly oral vinorelbine fur stage IV non-small-cell lung cancer. J Clin Oncol 1995; 13: 637-44
-
(1995)
J Clin Oncol
, vol.13
, pp. 637-644
-
-
Vokes, E.E.1
Rosenberg, R.K.2
Jahanzeb, M.3
-
31
-
-
0025910655
-
A phase II study of Navelbine (vinorelbine) in the treatment of non-small-cell lung cancer
-
Depierre A, Lemarie E, Dabouis G, et al. A Phase II study of Navelbine (vinorelbine) in the treatment of non-small-cell lung cancer. Am J Clin Oncol 1991; 14: 115-9
-
(1991)
Am J Clin Oncol
, vol.14
, pp. 115-119
-
-
Depierre, A.1
Lemarie, E.2
Dabouis, G.3
-
32
-
-
10144246570
-
Randomized trial of vinorelbine compared with fluorouracil plus leucovorin in patients with stage IV non-small-cell lung cancer
-
Crawford J, O'Rourke M, Schiller JH, et al. Randomized trial of vinorelbine compared with fluorouracil plus leucovorin in patients with stage IV non-small-cell lung cancer. J Clin Oncol 1996; 14: 2774-84
-
(1996)
J Clin Oncol
, vol.14
, pp. 2774-2784
-
-
Crawford, J.1
O'Rourke, M.2
Schiller, J.H.3
-
33
-
-
4244097603
-
Oral navelbine in women with previously treated advanced breast cancer: A US multicenler phase II trial
-
Spicer D, McCaskill-Stevens W, Oken M, et al. Oral Navelbine in women with previously treated advanced breast cancer: a US multicenler Phase II trial. Proc Am Soc Clin Oncol 1994; 13: 76A
-
(1994)
Proc Am Soc Clin Oncol
, vol.13
-
-
Spicer, D.1
McCaskill-Stevens, W.2
Oken, M.3
-
34
-
-
4243682012
-
Results of a study of the effect of food on the bioavailability and pharmacokinetics of Navelbine® liquid-filled soft gelatin capsules
-
Lucas S, Rowinsky E, Wargin W. Results of a study of the effect of food on the bioavailability and pharmacokinetics of Navelbine® liquid-filled soft gelatin capsules. Proc Am Soc Clin Oncol 1993; 12: 160A
-
(1993)
Proc Am Soc Clin Oncol
, vol.12
-
-
Lucas, S.1
Rowinsky, E.2
Wargin, W.3
-
35
-
-
0029820708
-
The effects of food and divided dosing on the hioavailahility of oral vinorelbine
-
Rowinsky EK, Lucas VS, Hsieh AL, et al. The effects of food and divided dosing on the hioavailahility of oral vinorelbine. Cancer Chemother Pharmacol 1996; 39: 9-16
-
(1996)
Cancer Chemother Pharmacol
, vol.39
, pp. 9-16
-
-
Rowinsky, E.K.1
Lucas, V.S.2
Hsieh, A.L.3
-
36
-
-
0029048587
-
Oral vinorelbine (navelbine) in the treatment of advanced breast cancer
-
Winer EP, Chu L, Spicer DV. Oral vinorelbine (navelbine) in the treatment of advanced breast cancer. Semin Oncol 1995; 22 Suppl. 5: 72-8
-
(1995)
Semin Oncol
, vol.22
, Issue.SUPPL. 5
, pp. 72-78
-
-
Winer, E.P.1
Chu, L.2
Spicer, D.V.3
-
37
-
-
0343744658
-
Pharmacokinetics of vinorelbine in breast cancer patients with liver metastases
-
Robieux I, Sorio R, Vitali V, et al. Pharmacokinetics of vinorelbine in breast cancer patients with liver metastases. Proc Am Soc Clin Oncol 1995; 14: 458A
-
(1995)
Proc Am Soc Clin Oncol
, vol.14
-
-
Robieux, I.1
Sorio, R.2
Vitali, V.3
-
38
-
-
37049053957
-
Inhibition of cell division in Escherichia coli by electrolysis products from a platinum electrode
-
Rosenberg B, Van Camp L, Krigas T. Inhibition of cell division in Escherichia coli by electrolysis products from a platinum electrode. Nature 1965; 205: 698-9
-
(1965)
Nature
, vol.205
, pp. 698-699
-
-
Rosenberg, B.1
Van Camp, L.2
Krigas, T.3
-
39
-
-
0014216382
-
The inhibition of growth or cell division in Escherichia coli by different ionic species of platinum (IV) complexes
-
Rosenberg B, Van Camp L, Grimley EB, et al. The inhibition of growth or cell division in Escherichia coli by different ionic species of platinum (IV) complexes. J Biol Chem 1967; 242: 1347-52
-
(1967)
J Biol Chem
, vol.242
, pp. 1347-1352
-
-
Rosenberg, B.1
Van Camp, L.2
Grimley, E.B.3
-
40
-
-
0014691619
-
Platinum compounds: A new class of potent antitumor agents
-
Rosenberg B, Van Camp L, Trosko JE, et al. Platinum compounds: a new class of potent antitumor agents. Nature 1969; 222: 385-6
-
(1969)
Nature
, vol.222
, pp. 385-386
-
-
Rosenberg, B.1
Van Camp, L.2
Trosko, J.E.3
-
41
-
-
0016210403
-
Diammine-dichloroplatinum: A phase I study showing responses in testicular and other tumors
-
Higby DJ, Wallace HJ, Albert DJ, et al. Diammine-dichloroplatinum: a Phase I study showing responses in testicular and other tumors. Cancer 1974; 33: 1219-25
-
(1974)
Cancer
, vol.33
, pp. 1219-1225
-
-
Higby, D.J.1
Wallace, H.J.2
Albert, D.J.3
-
42
-
-
0010458213
-
Antitumor, toxic and biochemical properties of cisplatin and eight other platinum complexes
-
Prestayko AW, editor. New York: Academic Press
-
Harrap KR, Jones M, Wilkinson CR, et al. Antitumor, toxic and biochemical properties of cisplatin and eight other platinum complexes. In: Prestayko AW, editor. Cisplatin: current status and new developments. New York: Academic Press, 1980: 193-212
-
(1980)
Cisplatin: Current Status and New Developments
, pp. 193-212
-
-
Harrap, K.R.1
Jones, M.2
Wilkinson, C.R.3
-
43
-
-
0024553731
-
A phase I clinical and pharmacokinetic study of carhoplatin and autologous bone marrow support
-
Shea TC, Flaherty M, Elias A, et al. A Phase I clinical and pharmacokinetic study of carhoplatin and autologous bone marrow support. J Clin Oncol 1989; 7: 651-61
-
(1989)
J Clin Oncol
, vol.7
, pp. 651-661
-
-
Shea, T.C.1
Flaherty, M.2
Elias, A.3
-
44
-
-
0026045712
-
Platinum coordination complexes which circumvent cisplatin resistance
-
Harrap KR, Kelland LR, Jones M, et al. Platinum coordination complexes which circumvent cisplatin resistance. Adv Enzyme Regul 1991; 31: 31-43
-
(1991)
Adv Enzyme Regul
, vol.31
, pp. 31-43
-
-
Harrap, K.R.1
Kelland, L.R.2
Jones, M.3
-
45
-
-
0005741390
-
A novel class of orally active platinum IV coordination complexes which circumvent cisplatin resistance in vitro
-
Harrap KR, Murrer BA, Giandomenico C, et al. A novel class of orally active platinum IV coordination complexes which circumvent cisplatin resistance in vitro. Proc Am Assoc Cancer Res 1991; 32: 428A
-
(1991)
Proc Am Assoc Cancer Res
, vol.32
-
-
Harrap, K.R.1
Murrer, B.A.2
Giandomenico, C.3
-
46
-
-
0005702667
-
New platinum drugs capable of oral administration
-
Harrap KR, Morgan SE, Murrer BA, et al. New platinum drugs capable of oral administration. Ann Oncol 1992; 3 Suppl. 1: 116A
-
(1992)
Ann Oncol
, vol.3
, Issue.SUPPL. 1
-
-
Harrap, K.R.1
Morgan, S.E.2
Murrer, B.A.3
-
47
-
-
0002684054
-
Synthesis and reactions of a new class of orally active Pt(IV) antitumor complexes
-
Howell SB, editor. New York: Plenum Publishing Corp.
-
Giandomenico CM, Abrams MJ, Murrer BA, et al. Synthesis and reactions of a new class of orally active Pt(IV) antitumor complexes. In: Howell SB, editor. Platinum and other metal coordination compounds in cancer chemotherapy. New York: Plenum Publishing Corp., 1991: 93-100
-
(1991)
Platinum and Other Metal Coordination Compounds in Cancer Chemotherapy
, pp. 93-100
-
-
Giandomenico, C.M.1
Abrams, M.J.2
Murrer, B.A.3
-
48
-
-
0342873980
-
Structure-activity relationships in a series of novel platinum (II) and platinum (IV) ammine/amine complexes evaluated against a panel of human ovarian carcinoma cell lines
-
Kelland LR, Murrer BA, Abel G, et al. Structure-activity relationships in a series of novel platinum (II) and platinum (IV) ammine/amine complexes evaluated against a panel of human ovarian carcinoma cell lines. J Cell Pharmacol 1991; 2: 331-42
-
(1991)
J Cell Pharmacol
, vol.2
, pp. 331-342
-
-
Kelland, L.R.1
Murrer, B.A.2
Abel, G.3
-
49
-
-
0026665349
-
Sensitivity to novel platinum compounds of panels of human lung cancer cell lines with acquired and inherent resistance to cisplatin
-
Twentyman PR, Wright KA, Mistry P, et al. Sensitivity to novel platinum compounds of panels of human lung cancer cell lines with acquired and inherent resistance to cisplatin. Cancer Res 1992; 52: 5674-80
-
(1992)
Cancer Res
, vol.52
, pp. 5674-5680
-
-
Twentyman, P.R.1
Wright, K.A.2
Mistry, P.3
-
50
-
-
24844434234
-
Circumvention of transport-mediated acquired cisplalin resistance in human cancer cell lines by the orally active platinum drug, Bis-acetatoammine dichloro(cyclohexylamine) platinum (IV) (JM216)
-
Kelland LR, Mellish KJ, Abel G, et al. Circumvention of transport-mediated acquired cisplalin resistance in human cancer cell lines by the orally active platinum drug, Bis-acetatoammine dichloro(cyclohexylamine) platinum (IV) (JM216). Proc Am Assoc Cancer Res 1993; 34: 400A
-
(1993)
Proc Am Assoc Cancer Res
, vol.34
-
-
Kelland, L.R.1
Mellish, K.J.2
Abel, G.3
-
51
-
-
0027275229
-
In vitro platinum drug chemosensitivity of human cervical squamous cell carcinoma cell lines with intrinsic and acquired resistance to cisplatin
-
Mellish KJ, Kelland LR, Harrap KR In vitro platinum drug chemosensitivity of human cervical squamous cell carcinoma cell lines with intrinsic and acquired resistance to cisplatin. Br J Cancer 1993; 63: 240-50
-
(1993)
Br J Cancer
, vol.63
, pp. 240-250
-
-
Mellish, K.J.1
Kelland, L.R.2
Harrap, K.R.3
-
52
-
-
0027207136
-
Preclinical antitumor activity of orally administered platinum (IV) complexes
-
Rose WC, Crosswell AR, Schurig JE, et al. Preclinical antitumor activity of orally administered platinum (IV) complexes. Cancer Chermother Pharmacol 1993; 32: 197-203
-
(1993)
Cancer Chermother Pharmacol
, vol.32
, pp. 197-203
-
-
Rose, W.C.1
Crosswell, A.R.2
Schurig, J.E.3
-
53
-
-
0029069670
-
Initiatives with platinum- and quinazoline-hased antitumor molecules - Fourteenth Bruce F. Cain memorial award lecture
-
Harrap KR. Initiatives with platinum- and quinazoline-hased antitumor molecules - Fourteenth Bruce F. Cain Memorial Award Lecture. Cancer Res 1995; 55: 2761-8
-
(1995)
Cancer Res
, vol.55
, pp. 2761-2768
-
-
Harrap, K.R.1
-
55
-
-
0026692952
-
Mechanism-related circumvention of acquired cis-diamminedichloroplatinum(II) resistance using two pairs of human ovarian carcinoma cell lines by ammine/amine platinum(IV) dicarboxylates
-
Kelland LR, Mistry P, Abel G, et al. Mechanism-related circumvention of acquired cis-diamminedichloroplatinum(II) resistance using two pairs of human ovarian carcinoma cell lines by ammine/amine platinum(IV) dicarboxylates. Cancer Res 1992; 52: 3857-64
-
(1992)
Cancer Res
, vol.52
, pp. 3857-3864
-
-
Kelland, L.R.1
Mistry, P.2
Abel, G.3
-
56
-
-
0026504232
-
Ammine/amine platinum(IV) dicarboxylate complexes: A novel class of platinum complex exhibiting selective cytotoxicity to intrinsically cisplatin-resistant human ovarian carcinoma cells lines
-
Kelland LR, Murrer BA, Abel G, et al. Ammine/amine platinum(IV) dicarboxylate complexes: a novel class of platinum complex exhibiting selective cytotoxicity to intrinsically cisplatin-resistant human ovarian carcinoma cells lines. Cancer Res 1992; 52: 822-8
-
(1992)
Cancer Res
, vol.52
, pp. 822-828
-
-
Kelland, L.R.1
Murrer, B.A.2
Abel, G.3
-
57
-
-
0028025381
-
Schedule dependency of orally administered bis-acetato-ammine-dichlorocyclohexytamine-platinum(IV) (JM216) in vivo
-
McKeage MJ, Kelland LR, Boxall FE, et al. Schedule dependency of orally administered bis-acetato-ammine-dichlorocyclohexytamine-platinum(IV) (JM216) in vivo. Cancer Res 1994; 54: 4118-22
-
(1994)
Cancer Res
, vol.54
, pp. 4118-4122
-
-
McKeage, M.J.1
Kelland, L.R.2
Boxall, F.E.3
-
58
-
-
0028345821
-
Preclinical toxicology and tissue platinum distribution of novel oral antitumor platinum complexes: Ammine/amine platinum (IV) dicarboxylates
-
McKeage MJ, Morgan SE, Boxall FE, et al. Preclinical toxicology and tissue platinum distribution of novel oral antitumor platinum complexes: ammine/amine platinum (IV) dicarboxylates. Cancer Chemother Pharmacol 1994; 33: 497-503
-
(1994)
Cancer Chemother Pharmacol
, vol.33
, pp. 497-503
-
-
McKeage, M.J.1
Morgan, S.E.2
Boxall, F.E.3
-
59
-
-
0027215201
-
Lack of nephrotoxicity of oral ammine/amine platinum(IV) dicarboxylate complexes in rodents
-
McKeage MJ, Morgan SE, Boxall FE, et al. Lack of nephrotoxicity of oral ammine/amine platinum(IV) dicarboxylate complexes in rodents. Br J Cancer 1993; 67: 996-1000
-
(1993)
Br J Cancer
, vol.67
, pp. 996-1000
-
-
McKeage, M.J.1
Morgan, S.E.2
Boxall, F.E.3
-
60
-
-
0029758018
-
Metabolism, protein binding and in vivo activity of the oral platinum drug JM216 and its hiotransformation products
-
Raynaud FI, Boxall FE, Goddard P, et al. Metabolism, protein binding and in vivo activity of the oral platinum drug JM216 and its hiotransformation products. Anticancer Res 1996; 16: 1857-62
-
(1996)
Anticancer Res
, vol.16
, pp. 1857-1862
-
-
Raynaud, F.I.1
Boxall, F.E.2
Goddard, P.3
-
61
-
-
0029089517
-
A phase I and pharmacology study of an oral platinum complex, JM216: Dose-dependent pharmacokinetics with single-dose administration
-
McKeage MJ, Mistry P, Ward J, et al. A Phase I and pharmacology study of an oral platinum complex, JM216: dose-dependent pharmacokinetics with single-dose administration. Cancer Chemother Pharmacol 1995; 36: 451-8
-
(1995)
Cancer Chemother Pharmacol
, vol.36
, pp. 451-458
-
-
McKeage, M.J.1
Mistry, P.2
Ward, J.3
-
62
-
-
0030742993
-
Phase 1 and pharmacokinetic study of an oral platinum complex given daily for 5 days in patients with cancer
-
McKeage MJ, Raynaud F, Ward J, et al. Phase 1 and pharmacokinetic study of an oral platinum complex given daily for 5 days in patients with cancer. J Clin Oncol 1997; 15: 2691-700
-
(1997)
J Clin Oncol
, vol.15
, pp. 2691-2700
-
-
McKeage, M.J.1
Raynaud, F.2
Ward, J.3
-
63
-
-
0031159653
-
Phase II trial of the oral platinum complex JM216 in non-small cell lung cancer: An EORTC early clinical studies group investigation
-
Judson I, Cerny T, Epelbaum R, et al. Phase II trial of the oral platinum complex JM216 in non-small cell lung cancer: an EORTC early clinical studies group investigation. Ann Oncol 1997; 8: 604-6
-
(1997)
Ann Oncol
, vol.8
, pp. 604-606
-
-
Judson, I.1
Cerny, T.2
Epelbaum, R.3
-
64
-
-
41549110421
-
Randomized phase II study of oral JM2 16 versus intravenous cisplatin in non-small cell lung cancer: Preliminary results
-
Fokkema E, Lunenberg J, van Putten JWG, et al. Randomized Phase II study of oral JM2 16 versus intravenous cisplatin in non-small cell lung cancer: preliminary results. Proc Am Soc Clin Oncol 1998; 17: 83A
-
(1998)
Proc Am Soc Clin Oncol
, vol.17
-
-
Fokkema, E.1
Lunenberg, J.2
Van Putten, J.W.G.3
-
65
-
-
0010267330
-
A phase II study of oral platinum JM-216 as first-line treatment in small cell lung cancer
-
Groen HJM, Smit EF, Bauer J, A Phase II study of oral platinum JM-216 as first-line treatment in small cell lung cancer. Proc Am Soc Clin Oncol 1996; 15: 378A
-
(1996)
Proc Am Soc Clin Oncol
, vol.15
-
-
Groen, H.J.M.1
Smit, E.F.2
Bauer, J.3
-
66
-
-
0026580034
-
Effects of concomitant eisplatin and radiotherapy on inoperable non-small-cell lung cancer
-
Schaake-Koning C, van den Bogaert W, Dalesio O, et al. Effects of concomitant eisplatin and radiotherapy on inoperable non-small-cell lung cancer. N Engl J Med 1992; 326: 524-30
-
(1992)
N Engl J Med
, vol.326
, pp. 524-530
-
-
Schaake-Koning, C.1
Van Den Bogaert, W.2
Dalesio, O.3
-
67
-
-
0031446578
-
Oral platinum analogue JM216, a radiosensitizer in oxic murine cells
-
van de Vaart PJ, Klaren HM, Hofland I, et al. Oral platinum analogue JM216, a radiosensitizer in oxic murine cells. Int J Radiat Biol 1997; 72: 675-83
-
(1997)
Int J Radiat Biol
, vol.72
, pp. 675-683
-
-
Van De Vaart, P.J.1
Klaren, H.M.2
Hofland, I.3
-
68
-
-
0008062845
-
Oral JM-216 plus concomitant radiotherapy for patients with advanced malignancies of the chest
-
Hoffman P, Mauer A, Haraf D. et al. Oral JM-216 plus concomitant radiotherapy for patients with advanced malignancies of the chest. Proc Am Soc Clin Oncol 1998; 17: 488A
-
(1998)
Proc Am Soc Clin Oncol
, vol.17
-
-
Hoffman, P.1
Mauer, A.2
Haraf D Et, A.3
-
69
-
-
0014895176
-
Preliminary pharmacologic and clinical evaluation of camptothecin sodium (NSC 100880)
-
Gottlieb JA, Guarino AM, Call JB, et al. Preliminary pharmacologic and clinical evaluation of camptothecin sodium (NSC 100880). Cancer Chemother Rep 1970; 54: 461-70
-
(1970)
Cancer Chemother Rep
, vol.54
, pp. 461-470
-
-
Gottlieb, J.A.1
Guarino, A.M.2
Call, J.B.3
-
70
-
-
0015378084
-
Phase I clinical trial of weekly and daily treatment with camptothecin (NSC 100880): Correlation with preclinical studies
-
Muggia FM, Creaven PJ, Hansen HH, et al. Phase I clinical trial of weekly and daily treatment with camptothecin (NSC 100880): correlation with preclinical studies. Cancer Chemother Rep 1972; 56: 515-21
-
(1972)
Cancer Chemother Rep
, vol.56
, pp. 515-521
-
-
Muggia, F.M.1
Creaven, P.J.2
Hansen, H.H.3
-
71
-
-
0029791237
-
New promising anticancer agents in development: What comes next?
-
Verweij J. New promising anticancer agents in development: what comes next? Cancer Chemother Pharmacol 1996; 38 Suppl.: S3-S10
-
(1996)
Cancer Chemother Pharmacol
, vol.38
, Issue.SUPPL.
-
-
Verweij, J.1
-
72
-
-
0015407723
-
Plasma camptothecin (NSC-100880) levels during a 5-day course of treatment: Relation to dose and toxicity
-
Creaven PJ, Allen LM, Muggia FM. Plasma camptothecin (NSC-100880) levels during a 5-day course of treatment: relation to dose and toxicity. Cancer Chemother Rep 1972; 56: 573-8
-
(1972)
Cancer Chemother Rep
, vol.56
, pp. 573-578
-
-
Creaven, P.J.1
Allen, L.M.2
Muggia, F.M.3
-
73
-
-
0015291595
-
Phase II study of camptothecin (NSC-100880) in the treatment of advanced gastrointestinal cancer
-
Moertel CCG, Schult AJ, Reitemeier RJ, et al. Phase II study of camptothecin (NSC-100880) in the treatment of advanced gastrointestinal cancer. Cancer Chemother Rev 1972; 56: 95-101
-
(1972)
Cancer Chemother Rev
, vol.56
, pp. 95-101
-
-
Moertel, C.C.G.1
Schult, A.J.2
Reitemeier, R.J.3
-
74
-
-
0021506823
-
Characterisation of size variant of type I DNA topoisomerase isolated from calf thymus
-
Schmitt B, Buhre U, Vosberg HP. Characterisation of size variant of type I DNA topoisomerase isolated from calf thymus. Eur J Biochem 1984; 144: 127-34
-
(1984)
Eur J Biochem
, vol.144
, pp. 127-134
-
-
Schmitt, B.1
Buhre, U.2
Vosberg, H.P.3
-
75
-
-
0000482574
-
Human DNA topoisomerase I is encoded by a single-copy gene that maps to chromosome region 20q 12-13.2
-
Juan C, Hwang J, Liu LF, et al. Human DNA topoisomerase I is encoded by a single-copy gene that maps to chromosome region 20q 12-13.2. Proc Natl Acad Sci USA 1988; 85: 8910-3
-
(1988)
Proc Natl Acad Sci USA
, vol.85
, pp. 8910-8913
-
-
Juan, C.1
Hwang, J.2
Liu, L.F.3
-
76
-
-
0015692519
-
Effects of camptothecin on the breakage and repair of DNA during the cell cycle
-
Horwitz SB, Horwitz MS. Effects of camptothecin on the breakage and repair of DNA during the cell cycle. Cancer Res 1973; 33: 2834-6
-
(1973)
Cancer Res
, vol.33
, pp. 2834-2836
-
-
Horwitz, S.B.1
Horwitz, M.S.2
-
77
-
-
0022340594
-
Camptothecin induces protein-limited DNA breaks via mammalian DNA topoisomerase I
-
Hsiang YH, Hertzberg R, Hecht S, et al. Camptothecin induces protein-limited DNA breaks via mammalian DNA topoisomerase I. J Biol Chem 1985; 260: 14873-8
-
(1985)
J Biol Chem
, vol.260
, pp. 14873-14878
-
-
Hsiang, Y.H.1
Hertzberg, R.2
Hecht, S.3
-
78
-
-
0023136543
-
Relationship between the intracellular effects of camptothecin and the inhibition of DNA topoisomerase I in cultured L1210 cells
-
Mattern MR, Mong SM, Bartus HF, et al. Relationship between the intracellular effects of camptothecin and the inhibition of DNA topoisomerase I in cultured L1210 cells. Cancer Res 1987; 47: 1793-8
-
(1987)
Cancer Res
, vol.47
, pp. 1793-1798
-
-
Mattern, M.R.1
Mong, S.M.2
Bartus, H.F.3
-
79
-
-
0024420685
-
Arrest of replication forks by drug stabilized topoisomerase-I-DNA cleavahle complexes as a mechanism of cell killing by camptothecin
-
Hsiang YH, Lihou MG, Liu LF. Arrest of replication forks by drug stabilized topoisomerase-I-DNA cleavahle complexes as a mechanism of cell killing by camptothecin. Cancer Res 1989; 49: 5077-82
-
(1989)
Cancer Res
, vol.49
, pp. 5077-5082
-
-
Hsiang, Y.H.1
Lihou, M.G.2
Liu, L.F.3
-
80
-
-
0024316466
-
DNA topoisomerasc poisons as antitumor drugs
-
Liu L. DNA topoisomerasc poisons as antitumor drugs. Ann Rev Biochem 1989; 58: 351-74
-
(1989)
Ann Rev Biochem
, vol.58
, pp. 351-374
-
-
Liu, L.1
-
82
-
-
0027972726
-
Topoisomerase 1 inhibitors: Lopotecan and irinotecan
-
Creemers GJ, Lund B, Verweij J. Topoisomerase 1 inhibitors: lopotecan and irinotecan. Cancer Treat Rev 1994; 20: 73-96
-
(1994)
Cancer Treat Rev
, vol.20
, pp. 73-96
-
-
Creemers, G.J.1
Lund, B.2
Verweij, J.3
-
83
-
-
0028225686
-
Comparative activity of oral and parenteral topotecan in murine tumor models: Efficacy of oral topotecan
-
McCabe FL, Johnson RK. Comparative activity of oral and parenteral topotecan in murine tumor models: efficacy of oral topotecan. Cancer Invest 1994; 12: 308-13
-
(1994)
Cancer Invest
, vol.12
, pp. 308-313
-
-
McCabe, F.L.1
Johnson, R.K.2
-
84
-
-
0031056424
-
Phase I and pharmacologic study of oral topotecan administered twice daily for 21 days to adult patients with solid tumors
-
Creemers GJ, Gerrits CJH, Eckardt JR, et al. Phase I and pharmacologic study of oral topotecan administered twice daily for 21 days to adult patients with solid tumors. J Clin Oncol 1997; 15: 1087-93
-
(1997)
J Clin Oncol
, vol.15
, pp. 1087-1093
-
-
Creemers, G.J.1
Gerrits, C.J.H.2
Eckardt, J.R.3
-
85
-
-
0024358188
-
DNA topoisomerase I-targeted chemotherapy of human colon cancer in xenografts
-
Giovanella BC, Stehlin JS, Wall ME, et al. DNA topoisomerase I-targeted chemotherapy of human colon cancer in xenografts. Science 1989; 246: 1046-8
-
(1989)
Science
, vol.246
, pp. 1046-1048
-
-
Giovanella, B.C.1
Stehlin, J.S.2
Wall, M.E.3
-
86
-
-
0026468470
-
Activity of topotecan, a new topoisomerase I inhibitor, against human tumor colony-forming units in vitro
-
Burris HA, Hanauske AR, Johnson RK, et al. Activity of topotecan, a new topoisomerase I inhibitor, against human tumor colony-forming units in vitro. J Natl Cancer Inst 1992; 84: 1816-20
-
(1992)
J Natl Cancer Inst
, vol.84
, pp. 1816-1820
-
-
Burris, H.A.1
Hanauske, A.R.2
Johnson, R.K.3
-
87
-
-
0026487210
-
Evaluation of 9-dimethylaminomethyl-10-hydroxycamptothecin (topotecan) against xenografts derived from adult and childhood tumors
-
Houghton PJ, Cheshire PJ, Myers L, et al. Evaluation of 9-dimethylaminomethyl-10-hydroxycamptothecin (topotecan) against xenografts derived from adult and childhood tumors. Cancer Chemother Pharmacol 1992; 31: 229-39
-
(1992)
Cancer Chemother Pharmacol
, vol.31
, pp. 229-239
-
-
Houghton, P.J.1
Cheshire, P.J.2
Myers, L.3
-
88
-
-
0027454410
-
Phase I and pharmacokinetics study of topotecan, a new topoisomerase I inhibitor
-
Verweij J, Lund B, Beijnen JH, et al. Phase I and pharmacokinetics study of topotecan, a new topoisomerase I inhibitor. Ann Oncol 1993; 4: 673-8
-
(1993)
Ann Oncol
, vol.4
, pp. 673-678
-
-
Verweij, J.1
Lund, B.2
Beijnen, J.H.3
-
89
-
-
0028357995
-
Phase I trial of low-dose continuous topotecan infusion in patients with cancer: An active and well-tolerated regimen
-
Hochster H, Liebes L, Speyer J, et al. Phase I trial of low-dose continuous topotecan infusion in patients with cancer: an active and well-tolerated regimen. J Clin Oncol 1994; 12: 553-9
-
(1994)
J Clin Oncol
, vol.12
, pp. 553-559
-
-
Hochster, H.1
Liebes, L.2
Speyer, J.3
-
90
-
-
0023924786
-
Identification of mammalian DNA topoisomerase I as an intracellular target of the anticancer drug camptothecin
-
Hsiang YH, Liu LF. Identification of mammalian DNA topoisomerase I as an intracellular target of the anticancer drug camptothecin. Cancer Res 1988; 48: 1722-6
-
(1988)
Cancer Res
, vol.48
, pp. 1722-1726
-
-
Hsiang, Y.H.1
Liu, L.F.2
-
91
-
-
0011636075
-
Phase II study of topotecan in refractory and sensitive small cell lung cancer
-
Ardizzoni A, Hansen HH, Dombernowsky P, et al. Phase II study of topotecan in refractory and sensitive small cell lung cancer. Eur J Cancer 1995; 31A Suppl. 5: S19
-
(1995)
Eur J Cancer
, vol.31 A
, Issue.SUPPL. 5
-
-
Ardizzoni, A.1
Hansen, H.H.2
Dombernowsky, P.3
-
92
-
-
0030482311
-
Clinical studies of topotecan
-
Broom C. Clinical studies of topotecan. Ann N Y Acad Sci 1996; 803: 264-71
-
(1996)
Ann N Y Acad Sci
, vol.803
, pp. 264-271
-
-
Broom, C.1
-
93
-
-
0026537874
-
Phase I and pharmacologic study of topotecan: A novel topoisomerase I inhibitor
-
Rowinsky EK, Grochow LB, Hendricks CB, et al. Phase I and pharmacologic study of topotecan: a novel topoisomerase I inhibitor. J Clin Oncol 1992; 10: 647-56
-
(1992)
J Clin Oncol
, vol.10
, pp. 647-656
-
-
Rowinsky, E.K.1
Grochow, L.B.2
Hendricks, C.B.3
-
94
-
-
0026697849
-
A phase I clinical and pharmacokinetic study of the topoisomerase I inhibitor, topotecan (SK&F 104864), given as an intravenous bolus every 21 days
-
Wall JA, Burris HA, Von Hoff DD, et al. A Phase I clinical and pharmacokinetic study of the topoisomerase I inhibitor, topotecan (SK&F 104864), given as an intravenous bolus every 21 days. Anticancer Drugs 1992; 3: 337-45
-
(1992)
Anticancer Drugs
, vol.3
, pp. 337-345
-
-
Wall, J.A.1
Burris, H.A.2
Von Hoff, D.D.3
-
95
-
-
0000943872
-
Phase II study of topotecan in extensive stage small cell lung cancer
-
Schiller JH, Kim K, Johnson, D. Phase II study of topotecan in extensive stage small cell lung cancer. Proc Am Soc Clin Oncol 1994; 13: 330A
-
(1994)
Proc Am Soc Clin Oncol
, vol.13
-
-
Schiller, J.H.1
Kim, K.2
-
96
-
-
0007704867
-
Topotecan versus cyclophosphamide, doxorubicin and vincristine for the treatment of patients with recurrent small cell lung cancer, a phase II study
-
Schiller J, Von Pawel J, Shepherd F, et al. Topotecan versus cyclophosphamide, doxorubicin and vincristine for the treatment of patients with recurrent small cell lung cancer, a Phase II study. Proc Am Soc Clin Oncol 1998; 17: 456A
-
(1998)
Proc Am Soc Clin Oncol
, vol.17
-
-
Schiller, J.1
Von Pawel, J.2
Shepherd, F.3
-
97
-
-
0029973829
-
Bioavailability and pharmacokinetics of oral topotecan: A new topoisomerase I inhibitor
-
Schellens JHM, Creemers GJ, Beijnen JH, et al. Bioavailability and pharmacokinetics of oral topotecan: a new topoisomerase I inhibitor. Br J Cancer 1996; 73: 1268-71
-
(1996)
Br J Cancer
, vol.73
, pp. 1268-1271
-
-
Schellens, J.H.M.1
Creemers, G.J.2
Beijnen, J.H.3
-
99
-
-
13344250486
-
Effects of novel retinoid x receptor-selective ligands on myeloid leukemic differentiation and proliferation in vitro
-
Kizaki M, Dawson MI, Heyman R, et al. Effects of novel retinoid X receptor-selective ligands on myeloid leukemic differentiation and proliferation in vitro. Blood 1996; 87: 1977-84
-
(1996)
Blood
, vol.87
, pp. 1977-1984
-
-
Kizaki, M.1
Dawson, M.I.2
Heyman, R.3
-
100
-
-
0028362475
-
Novel retinoic acid, 9-cis retinoic acid, in combination with all-Irans retinoic acid is an effective inducer of differentiation of retinoic acid-resistant HL-60 cells
-
Kizaki M, Nakajima H, Mori S, et al. Novel retinoic acid, 9-cis retinoic acid, in combination with all-Irans retinoic acid is an effective inducer of differentiation of retinoic acid-resistant HL-60 cells. Blood 1994; 83: 3289-97
-
(1994)
Blood
, vol.83
, pp. 3289-3297
-
-
Kizaki, M.1
Nakajima, H.2
Mori, S.3
-
101
-
-
0031024325
-
Initial clinical trial of a selective retinoid X receptor ligand, LGD1069
-
Miller VA, Benedetti FM, Rigas JR. et al. Initial clinical trial of a selective retinoid X receptor ligand, LGD1069. J Clin Oncol 1997; 15: 790-5
-
(1997)
J Clin Oncol
, vol.15
, pp. 790-795
-
-
Miller, V.A.1
Benedetti, F.M.2
Rigas, J.R.3
-
102
-
-
0028087742
-
Synthesis and structure-activity relationships of novel retinoid X receptor-selective retinoids
-
Boehm MF, Zhang L, Badea BA, et al. Synthesis and structure-activity relationships of novel retinoid X receptor-selective retinoids. J Med Chem 1994; 37: 2930-41
-
(1994)
J Med Chem
, vol.37
, pp. 2930-2941
-
-
Boehm, M.F.1
Zhang, L.2
Badea, B.A.3
-
103
-
-
0029097177
-
Design and synthesis of potent retinoid X receptor selective ligands that induce apoptosis in leukemia cells
-
Boehm MF, Zhang L, Zhi L, et al. Design and synthesis of potent retinoid X receptor selective ligands that induce apoptosis in leukemia cells. J Med Chem 1995; 38: 3146-55
-
(1995)
J Med Chem
, vol.38
, pp. 3146-3155
-
-
Boehm, M.F.1
Zhang, L.2
Zhi, L.3
-
104
-
-
0026536522
-
Retinoid X receptor is an auxiliary protein for thyroid hormone and retinoic acid receptors
-
Zhang XK, Hoffmann B, Tran PBV, et al. Retinoid X receptor is an auxiliary protein for thyroid hormone and retinoic acid receptors. Nature 1992; 355: 441-6
-
(1992)
Nature
, vol.355
, pp. 441-446
-
-
Zhang, X.K.1
Hoffmann, B.2
Tran, P.B.V.3
-
105
-
-
0026705751
-
Convergence of 9-cis retinoic acid and peroxisome proliferator signalling pathways through heterodimer formation of their receptors
-
Kliewer SA, Umesono K, Noonan DJ, et al. Convergence of 9-cis retinoic acid and peroxisome proliferator signalling pathways through heterodimer formation of their receptors. Nature 1992; 358: 771-4
-
(1992)
Nature
, vol.358
, pp. 771-774
-
-
Kliewer, S.A.1
Umesono, K.2
Noonan, D.J.3
-
106
-
-
0026742534
-
Multiplicity generates diversity in the retinoic acid signalling pathways
-
Leid M, Kastner P, Chambon P. Multiplicity generates diversity in the retinoic acid signalling pathways. Trends Biochem Sci 1992; 17: 427-33
-
(1992)
Trends Biochem Sci
, vol.17
, pp. 427-433
-
-
Leid, M.1
Kastner, P.2
Chambon, P.3
-
107
-
-
0029063607
-
Activation of retinoid X receptors induces apoptosis in HL-60 cell lines
-
Nagy L, Thomazy VA, Shipley GL, et al. Activation of retinoid X receptors induces apoptosis in HL-60 cell lines. Mol Cell Biol 1995; 15: 3540-51
-
(1995)
Mol Cell Biol
, vol.15
, pp. 3540-3551
-
-
Nagy, L.1
Thomazy, V.A.2
Shipley, G.L.3
-
109
-
-
0018414126
-
Prolonged remissions of cystic and conglobate acne with 13-cis-retinoic acid
-
Peck GL, Olsen TG, Yoder KW. Prolonged remissions of cystic and conglobate acne with 13-cis-retinoic acid. N Engl J Med 1979; 300: 329-33
-
(1979)
N Engl J Med
, vol.300
, pp. 329-333
-
-
Peck, G.L.1
Olsen, T.G.2
Yoder, K.W.3
-
111
-
-
0020035723
-
Isotretinoid versus placebo in the treatment of cystic acne. A randomized double-blind study
-
Peck GL, Olsen TG, Butkus D, et al. Isotretinoid versus placebo in the treatment of cystic acne. A randomized double-blind study. J Am Acad Dermatol 1982; 6: 735-45
-
(1982)
J Am Acad Dermatol
, vol.6
, pp. 735-745
-
-
Peck, G.L.1
Olsen, T.G.2
Butkus, D.3
-
112
-
-
0026583597
-
13-cis-Retinoic acid and Interferon α-2a: Effective combination therapy for advanced squamous cell carcinoma of the skin
-
Lippman SM, Parkinson DR, Itri LM. et al. 13-cis-Retinoic acid and Interferon α-2a: effective combination therapy for advanced squamous cell carcinoma of the skin. J Natl Cancer Inst 1992; 84: 235-41
-
(1992)
J Natl Cancer Inst
, vol.84
, pp. 235-241
-
-
Lippman, S.M.1
Parkinson, D.R.2
Itri, L.M.3
-
113
-
-
0026600705
-
13-cis-Retinoic acid plus interferon α-2a: Highly active systemic therapy for squamous cell carcinoma of the cervix
-
Lippman SM, Kavanagh JJ, Paredes Espinoza M, et al. 13-cis-Retinoic acid plus interferon α-2a: highly active systemic therapy for squamous cell carcinoma of the cervix. J Natl Cancer Inst 1992; 84: 241-5
-
(1992)
J Natl Cancer Inst
, vol.84
, pp. 241-245
-
-
Lippman, S.M.1
Kavanagh, J.J.2
Paredes Espinoza, M.3
-
114
-
-
0027518643
-
Regression of oral leukoplakia with alpha-tocopherol: A community clinical oncology program chemotherapy study
-
Benner SE, Winn RJ, Lippman SM, et al. Regression of oral leukoplakia with alpha-tocopherol: a community clinical oncology program chemotherapy study. J Natl Cancer Inst 1993; 85: 44-7
-
(1993)
J Natl Cancer Inst
, vol.85
, pp. 44-47
-
-
Benner, S.E.1
Winn, R.J.2
Lippman, S.M.3
-
115
-
-
0027938555
-
Retinoid chemoprevention of second primary tumors
-
Benner SE, Lippman SM, Hong WK. Retinoid chemoprevention of second primary tumors. Semin Hematol 1994; 31 Suppl. 5: 26-30
-
(1994)
Semin Hematol
, vol.31
, Issue.SUPPL. 5
, pp. 26-30
-
-
Benner, S.E.1
Lippman, S.M.2
Hong, W.K.3
-
116
-
-
0020506009
-
Induction of differentiation of human acute myelogenous leukemia cells: Therapeutic implications
-
Koeffler P. Induction of differentiation of human acute myelogenous leukemia cells: therapeutic implications. Blood 1983; 62: 709-21
-
(1983)
Blood
, vol.62
, pp. 709-721
-
-
Koeffler, P.1
-
117
-
-
0020076632
-
Retinoic acid. Inhibition of the clonal growth of human myeloid leukemia cells
-
Douer D, Koeffler P. Retinoic acid. Inhibition of the clonal growth of human myeloid leukemia cells. J Clin Invest 1982; 69: 277-83
-
(1982)
J Clin Invest
, vol.69
, pp. 277-283
-
-
Douer, D.1
Koeffler, P.2
-
118
-
-
0025683226
-
Inhibition of tumor cell growth by relinoids
-
Lotan R, Lotan D, Sacks PG. Inhibition of tumor cell growth by relinoids. Methods Enzymol 1990; 190: 100-10
-
(1990)
Methods Enzymol
, vol.190
, pp. 100-110
-
-
Lotan, R.1
Lotan, D.2
Sacks, P.G.3
-
119
-
-
0023752982
-
Use of all-trans retinoic acid in the treatment of acute promyelocytic leukemia
-
Huang ME, Ye YC, Chen SR, et al. Use of all-trans retinoic acid in the treatment of acute promyelocytic leukemia. Blood 1988; 72: 567-72
-
(1988)
Blood
, vol.72
, pp. 567-572
-
-
Huang, M.E.1
Ye, Y.C.2
Chen, S.R.3
-
120
-
-
0025201879
-
All-trans retinoic acid as a differentiation therapy for acute promyelocytic leukemia. 1. Clinical results
-
Castaigne S, Chomienne C, Daniel MT, et al. All-trans retinoic acid as a differentiation therapy for acute promyelocytic leukemia. 1. Clinical results. Blood 1990; 76: 1704-9
-
(1990)
Blood
, vol.76
, pp. 1704-1709
-
-
Castaigne, S.1
Chomienne, C.2
Daniel, M.T.3
-
121
-
-
0026040363
-
A clinical and experimental study on all-trans retinoic acid-treated acute promyelocytic patients
-
Chen ZX, Xue YQ, Zhang R, et al. A clinical and experimental study on all-trans retinoic acid-treated acute promyelocytic patients. Blood 1991; 78: 1413-9
-
(1991)
Blood
, vol.78
, pp. 1413-1419
-
-
Chen, Z.X.1
Xue, Y.Q.2
Zhang, R.3
-
122
-
-
0029050432
-
9-cis retinoic acid induces complete remission but does not reverse clinically acquired retinoid resistance in acute promyelocytic leukemia
-
Miller Jr WH, Jakubowski A, Tong WP, et al. 9-cis retinoic acid induces complete remission but does not reverse clinically acquired retinoid resistance in acute promyelocytic leukemia. Blood 1995; 85: 3021-7
-
(1995)
Blood
, vol.85
, pp. 3021-3027
-
-
Miller W.H., Jr.1
Jakubowski, A.2
Tong, W.P.3
-
123
-
-
0027332981
-
N-(4-hydroxyphenyl)retinamide induces apoptosis of malignant hemopoietic cell lines including those unresponsive to retinoic acid
-
Delia D, Aiello A, Lombardi L, et al. N-(4-hydroxyphenyl)retinamide induces apoptosis of malignant hemopoietic cell lines including those unresponsive to retinoic acid. Cancer Res 1993; 53: 6036-41
-
(1993)
Cancer Res
, vol.53
, pp. 6036-6041
-
-
Delia, D.1
Aiello, A.2
Lombardi, L.3
-
124
-
-
0030071518
-
Activation of retinoid receptors RAR-a and RXR-a induces differentiation and apoptosis, respectively, in HL-60 cells
-
Mehta K, McQueen T, Neamati N. Activation of retinoid receptors RAR-a and RXR-a induces differentiation and apoptosis, respectively, in HL-60 cells. Cell Growth Differ 1996; 7: 179-86
-
(1996)
Cell Growth Differ
, vol.7
, pp. 179-186
-
-
Mehta, K.1
McQueen, T.2
Neamati, N.3
-
125
-
-
0030846066
-
Oxidative metabolism of a retinoid and rapid phase II metabolite identification by mass spectrometry
-
Shirley MA, Wheelan P, Howell SR, et al. Oxidative metabolism of a retinoid and rapid phase II metabolite identification by mass spectrometry. Drug Metab Dispos 1997; 25: 1144-9
-
(1997)
Drug Metab Dispos
, vol.25
, pp. 1144-1149
-
-
Shirley, M.A.1
Wheelan, P.2
Howell, S.R.3
-
126
-
-
0029731340
-
Chemoprevention of mammary carcinoma by LGD1069 (Targretin): An RXR-selective ligand
-
Gottardis MM, Bischoff ED, Shirley MA, et al. Chemoprevention of mammary carcinoma by LGD1069 (Targretin): an RXR-selective ligand. Cancer Res 1996; 56: 5566-70
-
(1996)
Cancer Res
, vol.56
, pp. 5566-5570
-
-
Gottardis, M.M.1
Bischoff, E.D.2
Shirley, M.A.3
-
127
-
-
0032006028
-
Beyond tamoxifen: The retinoid X receptor-selective ligand LGD1069 (Targretin) causes complete regression of mammary carcinoma
-
Bischoff ED, Gottardis MM, Moon TE, et al. Beyond tamoxifen: the retinoid X receptor-selective ligand LGD1069 (Targretin) causes complete regression of mammary carcinoma. Cancer Res 1998; 58: 479-84
-
(1998)
Cancer Res
, vol.58
, pp. 479-484
-
-
Bischoff, E.D.1
Gottardis, M.M.2
Moon, T.E.3
-
128
-
-
0019508833
-
Purification of rabbit bone inhibitor of collagenase
-
Cawston TE, Galloway WA, Mercer E, et al. Purification of rabbit bone inhibitor of collagenase. Biochem J 1981; 195: 159-65
-
(1981)
Biochem J
, vol.195
, pp. 159-165
-
-
Cawston, T.E.1
Galloway, W.A.2
Mercer, E.3
-
129
-
-
0021325829
-
Extracts of human articular cartilage contain an inhibitor of tissue metalloproteinases
-
Dean DD, Woessner Jr JF. Extracts of human articular cartilage contain an inhibitor of tissue metalloproteinases. Biochem J 1984; 218: 277-80
-
(1984)
Biochem J
, vol.218
, pp. 277-280
-
-
Dean, D.D.1
Woessner J.F., Jr.2
-
130
-
-
0025317277
-
The role of stromelysin in the cartilage destruction that accompanies inflammatory arthritis
-
Hasty KA, Reife RA, Kang AH, et al. The role of stromelysin in the cartilage destruction that accompanies inflammatory arthritis. Arthritis Rheum 1990; 33: 388-97
-
(1990)
Arthritis Rheum
, vol.33
, pp. 388-397
-
-
Hasty, K.A.1
Reife, R.A.2
Kang, A.H.3
-
131
-
-
0000278013
-
Matrix inetalloproteinase inhibitors: A new class of anticancer agent
-
Brown PD. Matrix inetalloproteinase inhibitors: a new class of anticancer agent. Curr Opin Invest Drugs 1993; 2: 617-26
-
(1993)
Curr Opin Invest Drugs
, vol.2
, pp. 617-626
-
-
Brown, P.D.1
-
132
-
-
0001419988
-
Bay 12-9566, a novel, biphenyl matrix metalloproteinase inhibitor, demonstrates anti-invasive and anti-angiogenic properties
-
Hibner B, Card A, Flynn C, et al. Bay 12-9566, a novel, biphenyl matrix metalloproteinase inhibitor, demonstrates anti-invasive and anti-angiogenic properties. Proc Am Assoc Cancer Res 1998; 39: 302A
-
(1998)
Proc Am Assoc Cancer Res
, vol.39
-
-
Hibner, B.1
Card, A.2
Flynn, C.3
-
133
-
-
0001419989
-
Activity of the biphenyl matrix metalloproteinase inhibitor BAY 12-9566 in murine in vivo models
-
Bull C, Flynn C, Eberwein D, et al. Activity of the biphenyl matrix metalloproteinase inhibitor BAY 12-9566 in murine in vivo models. Proc Am Assoc Cancer Res 1998; 39: 302A
-
(1998)
Proc Am Assoc Cancer Res
, vol.39
-
-
Bull, C.1
Flynn, C.2
Eberwein, D.3
-
134
-
-
0000823543
-
Anti-metastatic activity of BAY 12-9566 in a human colon carcinoma HCT 116 orthotopic model
-
Flynn C, Bull C, Eberwein D, et al. Anti-metastatic activity of BAY 12-9566 in a human colon carcinoma HCT 116 orthotopic model. Proc Am Assoc Cancer Res 1998; 39: 301A
-
(1998)
Proc Am Assoc Cancer Res
, vol.39
-
-
Flynn, C.1
Bull, C.2
Eberwein, D.3
-
135
-
-
0001719456
-
Comparative pharmacokinetics of BAY 12-9566, a metalloproteinase inhibitor, in healthy volunteers and cancer patients
-
Shah A, Sundaresan P, Humphrey R, et al. Comparative pharmacokinetics of BAY 12-9566, a metalloproteinase inhibitor, in healthy volunteers and cancer patients. Proc Am Assoc Cancer Res 1998; 39: 521A
-
(1998)
Proc Am Assoc Cancer Res
, vol.39
-
-
Shah, A.1
Sundaresan, P.2
Humphrey, R.3
-
136
-
-
0000550788
-
Pharmacokinetics of BAY12-9566: Early results of a Canadian phase I dose escalation study in cancer patients
-
Hirte H, Goel R, Major P, et al. Pharmacokinetics of BAY12-9566: early results of a Canadian Phase I dose escalation study in cancer patients. Proc Am Assoc Cancer Res 1998; 39: 364A
-
(1998)
Proc Am Assoc Cancer Res
, vol.39
-
-
Hirte, H.1
Goel, R.2
Major, P.3
-
137
-
-
0033512761
-
The role of tegafur.uracil in pulmonary malignancy
-
Langer CJ. The role of tegafur.uracil in pulmonary malignancy. Drugs 1999; 58 Suppl. 3: 71-5
-
(1999)
Drugs
, vol.58
, Issue.SUPPL. 3
, pp. 71-75
-
-
Langer, C.J.1
|