Androgen receptor signalling: Comparative analysis of androgen response elements and implication of heat-shock protein 90 and 14-3-3η

Molecular and Cellular Endocrinology

Volumn 173, Issue 1-2, 2001, Pages 63-73

  Haendler, B ^a   Schuttke I ^a   Schleuning, W D ^a  

^a BAYER PHARMA AG   (Germany)

Author keywords

14 3 3 protein; Androgen receptor; Cysteine rich secretory protein; Heat shock protein 90; Promoter

Indexed keywords

ANDROGEN; ANDROGEN RECEPTOR; CHAPERONE; CYSTEINE RICH SECRETORY PROTEIN 1; CYSTEINE RICH SECRETORY PROTEON 3; GELDANAMYCIN; HEAT SHOCK PROTEIN 90; METRIBOLONE; PROTEIN 14 3 3; RADICICOL; SECRETORY PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL LINE; CONTROLLED STUDY; DNA RESPONSIVE ELEMENT; DOSE RESPONSE; ELECTROPHORESIS; GENE EXPRESSION REGULATION; GENE TRANSFER; HORMONE ACTION; IN VITRO STUDY; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN ANALYSIS; SIGNAL TRANSDUCTION; TRANSACTIVATION;

14-3-3 PROTEINS; BENZOQUINONES; CELL LINE; ENZYME INHIBITORS; GENES, REPORTER; HSP90 HEAT-SHOCK PROTEINS; HUMANS; LACTAMS, MACROCYCLIC; LACTONES; MACROLIDES; MALE; MEMBRANE GLYCOPROTEINS; METRIBOLONE; MOLECULAR SEQUENCE DATA; PROMOTER REGIONS (GENETICS); PROSTATE; QUINONES; RECEPTORS, ANDROGEN; RESPONSE ELEMENTS; SALIVARY PROTEINS; SEMINAL PLASMA PROTEINS; SIGNAL TRANSDUCTION; TESTOSTERONE CONGENERS; TRANS-ACTIVATION (GENETICS); TYROSINE 3-MONOOXYGENASE;

EID: 0035932022     PISSN: 03037207     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0303-7207(00)00434-2     Document Type: Article

References (53)

1. Multiple components of a complex androgen-dependent enhancer
2. The stringency and magnitude of androgen-specific gene activation are combinatorial functions of receptor and nonreceptor binding site sequences
3. Inhibition of mineralocorticoid and glucocorticoid receptor function by the heat shock protein 90-binding agent geldanamycin
4. Mechanism of androgen receptor activation and function
5. Androgen-regulated epididymal secretory proteins associated with post-testicular sperm development
6. Regulation of gene expression by steroid hormones
7. Functional characterization of an androgen response element in the first intron of the C3(1) gene of prostatic binding protein
8. The androgen-specific probasin response element 2 interacts differentially with androgen and glucocorticoid receptors
9. An androgen response element in a far upstream enhancer region is essential for high, androgen-regulated activity of the prostate-specific antigen promoter
10. Recovery from Hemophilia B Leyden: an androgen-responsive element in the factor IX promoter
11. Coregulatory proteins in nuclear hormone receptor action
12. Hsp90 regulates androgen receptor hormone binding affinity in vivo
13. Anatomy of the steroid receptor zinc finger region
14. Mineralocorticoids, glucocorticoids, receptors and response elements
15. Structural organization and regulation of the gene for the androgen-dependent glutathione peroxidase-like protein specific to the mouse epididymis
16. The first exon of the human sc gene contains an androgen responsive unit and an interferon regulatory factor element
17. Transcripts for cysteine-rich secretory protein-1 (CRISP-1; DE/AEG) and the novel related CRISP-3 are expressed under androgen control in the mouse salivary gland
18. Differential androgen regulation of the murine genes for cysteine-rich secretory proteins (CRISP)
19. Expression of transcripts for cysteine-rich secretory proteins (CRISPs) in the murine lacrimal gland
20. cDNA cloning and chromosome assignment of the gene for human brain 14-3-3 protein η chain
21. Androgen receptor and mechanism of androgen action
22. The human cysteine-rich secretory protein (CRISP) family
23. Binding of 14-3-3 proteins and nuclear export control the intracellular localization of the mitotic inducer Cdc25
24. Characterization of an androgen response element within the promoter of the epididymis-specific murine glutathione peroxidase 5 gene
25. Androgen regulation of the cyclin-dependent kinase inhibitor p21 gene through an androgen response element in the proximal promoter
26. Interaction of the 90-kDa heat shock protein with native and in vitro translated androgen receptor and receptor fragments
27. Specificity of simple hormone response elements in androgen regulated genes
28. Cross-talk between nuclear factor-κB and the steroid hormone receptors: mechanisms of mutual antagonism
29. Androgen induction of human prostate-specific kallikrein, hKLK2: characterization of an androgen response element in the 5′ promoter region of the gene
30. Activation of the human androgen receptor through a protein kinase A signaling pathway
31. Association of the 90-kDa heat shock protein does not affect the ligand-binding ability of androgen receptor
32. Extreme position dependence of a canonical hormone response element
33. The Mr 90,000 heat shock protein-free androgen receptor has a high affinity for steroid, in contrast to the glucocorticoid receptor
34. Mutual transcriptional interference between ReIA and androgen receptor
35. Rapid signalling by androgen receptor in prostate cancer cells
36. CRISP-3, a protein with homology to plant defense proteins, is expressed in mouse B cells under the control of Oct2
37. Steroid receptor interactions with heat shock protein and immunophilin chaperones
38. Characterization of two cis-acting DNA elements involved in the androgen regulation of the probasin gene
39. The roles of 14-3-3 proteins in signal transduction
40. The promoter of the prostate-specific antigen gene contains a functional androgen responsive element
41. Nuclear hormone coregulators in action: diversity for shared tasks
42. A consensus DNA-binding site for the androgen receptor
43. Regulation of androgen action
44. Interaction of radicicol with members of the heat shock protein 90 family of molecular chaperones
45. Isolation and characterization of the androgen-dependent mouse cysteine-rich secretory protein-3 (CRISP-3) gene
46. Isolation and characterization of the androgen-dependent mouse cysteine-rich secretory protein-1 (CRISP-1) gene
47. The function of steroid hormone receptors is inhibited by the hsp90-specific compound geldanamycin
48. Cloning and characterization of an androgen-dependent acidic epididymal glycoprotein/CRISP1-like protein from the monkey
49. Crystal structure of an Hsp90-geldanamycin complex: targeting of a protein chaperone by an antitumor agent
50. Hormone-induced dissociation of the androgen receptor-heat shock protein complex: use of a new monoclonal antibody to distinguish transformed from nontransformed receptors
51. Interaction of the ligand-activated glucocorticoid receptor with the 14-3-3η protein
52. Expression of androgen receptor in insect cells. Purification of the receptor and renaturation of its steroid- and DNA-binding functions
53. Nuclear localization of protein kinase U-α is regulated by 14-3-3