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Bioorganic and Medicinal Chemistry Letters

Volumn 11, Issue 2, 2001, Pages 227-230

Solid-phase optimisation of achiral amidinobenzyl indoles as potent and selective factor Xa inhibitors

(4) Heinelt, Uwe a Herok, Silke a Matter, Hans a Wildgoose, Peter a

a SANOFI AVENTIS DEUTSCHLAND GMBH (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

AMIDINE; BENZYL DERIVATIVE; BLOOD CLOTTING FACTOR 10A INHIBITOR; INDOLE DERIVATIVE;

ARTICLE; DRUG POTENCY; DRUG SELECTIVITY; DRUG SOLUBILITY; DRUG SYNTHESIS; LIPID SOLUBILITY;

AMIDES; BINDING SITES; COMBINATORIAL CHEMISTRY TECHNIQUES; DRUG DESIGN; ELECTROSTATICS; FACTOR XA; HUMANS; INDOLES; KINETICS; SERINE PROTEINASE INHIBITORS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0035931468 PISSN: 0960894X EISSN: None Source Type: Journal
DOI: 10.1016/S0960-894X(00)00631-4 Document Type: Article

Times cited : (19)

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