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Bioorganic and Medicinal Chemistry Letters

Volumn 11, Issue 2, 2001, Pages 219-222

Design, synthesis, and biological evaluation of HIV/FIV protease inhibitors incorporating a conformationally constrained macrocycle with a small P3′ residue

(5) Mak, Chi Ching a Le, Van Duc a Lin, Ying Chuan a Elder, John H a Wong, Chi Huey a

a SCRIPPS RESEARCH INSTITUTE (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MACROCYCLIC COMPOUND; PROTEINASE INHIBITOR;

ARTICLE; DRUG ACTIVITY; DRUG DESIGN; DRUG SCREENING; DRUG SYNTHESIS; ENZYME INHIBITION; HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS INFECTION;

AMINO ACID MOTIFS; AMINOCAPROIC ACIDS; ANTIVIRAL AGENTS; ASPARTIC ENDOPEPTIDASES; COMBINATORIAL CHEMISTRY TECHNIQUES; DRUG DESIGN; DRUG RESISTANCE; HIV PROTEASE INHIBITORS; IMMUNODEFICIENCY VIRUS, FELINE; INHIBITORY CONCENTRATION 50; MOLECULAR CONFORMATION; MOLECULAR MIMICRY; PEPTIDES, CYCLIC; PROTEASE INHIBITORS; STRUCTURE-ACTIVITY RELATIONSHIP;

FELINE IMMUNODEFICIENCY VIRUS;

EID: 0035931467 PISSN: 0960894X EISSN: None Source Type: Journal
DOI: 10.1016/S0960-894X(00)00641-7 Document Type: Article

Times cited : (15)

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