Novel non-glycerol-based cytofectins with lactic acid-derived head groups

Biochemical and Biophysical Research Communications

Volumn 289, Issue 5, 2001, Pages 1057-1062

  Ananta Laxmi, Ayyagari ^a   Vijayalakshmi, Penumarthy ^a   Balagopala Kaimal, Thengumpillil Narayana ^a   Chaudhuri, Arabinda ^a   Ramadas, Yerramsetti ^b   Rao, Nalam Madhusudhana ^b  

^a INDIAN INSTITUTE OF CHEMICAL TECHNOLOGY   (India)

^b CENTRE FOR CELLULAR AND MOLECULAR BIOLOGY   (India)

Author keywords

Cationic lipids; Cytofectins; Lipid: DNA interactions; Lipofection; Lipoplexes; Non viral gene delivery; Transfection

Indexed keywords

ETHIDIUM BROMIDE; LACTIC ACID; LIPID;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DRUG DESIGN; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS; EMBRYO; GENE INTERACTION; GENE TARGETING; GENETIC TRANSFECTION; MOUSE; NONHUMAN; PRIORITY JOURNAL; STRUCTURE ANALYSIS; TOXICITY TESTING;

EID: 0035930931     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1006/bbrc.2001.6065     Document Type: Article

References (33)

1. Gene therapy: The first decade
2. Gene therapeutics
3. Lipofectin: A highly efficient lipid-mediated DNA transaction procedure
4. A novel cationic liposome reagent for efficient transfection of mammalian cells
5. Efficient gene transfer into mammalian primary endocrine cells with lipopolyamine-coated DNA
6. Detailed analysis of structures and formulations of cationic lipids for efficient gene transfer to the lung
7. Enhanced gene delivery and mechanism studies with a novel series of cationic lipid formulations
8. Synthetic DNA delivery systems
9. Non-viral gene therapy: Promises and challenges
10. Cationic liposomes in gene therapy
11. Mannose receptor-mediated gene transfer into macrophages using novel mannosylated cationic liposomes
12. Novel series of non-glycerol-based cationic transfection lipids for use in liposomal gene delivery
13. Design, synthesis and transfection biology of novel cationic glycolipids for use in liposomal gene delivery
14. Anchor-dependency for non-glycerol based cationic lipofectins: Mixed bag of regular and anomalous transfection profiles
15. A transfection compound series based on a versatile Tris linkage
16. Synthesis and characterization of long chain alkyl acyl carnitine esters. Potentially biodegradable cationic lipids for use in gene delivery
17. Synthesis, activity and structure-activity relationship studies of novel cationic lipids for DNA transfer
18. Reduction-sensitive lipopolyamines as a novel non viral gene delivery system for modulated release of DNA with improved transgene expression
19. Cationic lipid-mediated gene delivery to murine lung: Correlation of lipid hydration with in vivo transfection activity
20. Phospholipids as non-viral vectors for gene therapy
21. Asialoglycoprotein receptor-mediated gene transfer using novel galactosylated cationic liposomes
22. Novel tetraester construct that reduces cationic lipid-associated cytotoxicity. Implications for the onset of cytotoxicity
23. Factors influencing the efficiency of cationic liposome-mediated intravenous gene delivery
24. Improved DNA: Liposome complexes for increased systemic delivery and gene expression
25. Liposome-mediated CFTR gene transfer to the nasal epithelium of patients with cystic fibrosis
26. Potential of cationic liposome-mediated gene delivery by polycations
27. Formation of stable cationic lipid/DNA complexes for gene transfer
28. Novel cationic lipid greatly enhances plasmid DNA delivery and expression in mouse lung
29. A novel series of amphiphilic imidazolinium compounds for in vitro and in vivo gene delivery
30. Cationic liposome-mediated intravenous gene delivery in mice
31. Non-invasive liposome-mediated gene delivery can correct the ion-transport defect in cystic fibrosis mutant mice
32. Interactions of mammalian cells with lipid dispersions containing novel metabolizable cat-ionic amphiphiles