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Volumn 287, Issue 2, 2001, Pages 397-401

Intracellular depletion of insulin by oleate is due to an inhibited synthesis and not to an increased secretion

Author keywords

[No Author keywords available]

Indexed keywords

C PEPTIDE; INSULIN; OLEIC ACID; PROINSULIN;

EID: 0035929370     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1006/bbrc.2001.5604     Document Type: Article
Times cited : (8)

References (23)
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  • 5
    • 0040503709 scopus 로고    scopus 로고
    • Enhancing effects of long-term elevated glucose and palmitate on stored and secreted proinsulin-to-insulin ratios in human pancreatic islets
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    • Bjorklund, A.1    Grill, V.2
  • 8
    • 0028268936 scopus 로고
    • Long-term exposure of rat pancreatic islets to fatty acids inhibits glucose-induced insulin secretion and biosynthesis through a glucose fatty acid cycle
    • (1994) J. Clin. Inves.t , vol.93 , pp. 870-876
    • Zhou, Y.P.1    Grill, V.E.2
  • 10
    • 0019311577 scopus 로고
    • Intracellular degradation of insulin stores by rat pancreatic islets in vitro. An alternative pathway for homeostasis of pancreatic insulin content
    • (1980) J. Biol. Chem. , vol.255 , pp. 6003-6006
    • Halban, P.A.1    Wollheim, C.B.2
  • 12
    • 0023990161 scopus 로고
    • The intracellular handling of insulin-related peptides in isolated pancreatic islets. Evidence for differential rates of degradation of insulin and C-peptide
    • (1988) Biochem. J. , vol.251 , pp. 23-30
    • Rhodes, C.J.1    Halban, P.A.2
  • 16
    • 0026468362 scopus 로고
    • What if Minkowski had been ageusic? An alternative angle on diabetes
    • (1992) Science , vol.258 , pp. 766-770
    • McGarry, J.D.1
  • 17
    • 0029151863 scopus 로고
    • Lipotoxicity in the pathogenesis of obesity-dependent NIDDM. Genetic and clinical implications
    • (1995) Diabetes , vol.44 , pp. 863-870
    • Unger, R.H.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.